公开(公告)号：CA2005741A1

公开(公告)日：1990-06-26

申请号：CA2005741

申请日：1989-12-15

Applicant: HIDAKA HIROYOSHI ,  ISHIKAWA TOMOHIKO ,  HAGIWARA MASATOSHI ,  INOUE TSUTOMU ,  NAITOH KENJI ,  SAKUMA OSAMU ,  YUASA MASAYUKI ,  MORITA TADASHI ,  TOSHIOKA TADASHI ,  UMEZAWA ISAO ,  INABA TAKASHI

Inventor： HIDAKA HIROYOSHI ,  ISHIKAWA TOMOHIKO ,  HAGIWARA MASATOSHI ,  INOUE TSUTOMU ,  NAITOH KENJI ,  SAKUMA OSAMU ,  YUASA MASAYUKI ,  MORITA TADASHI ,  TOSHIOKA TADASHI ,  UMEZAWA ISAO ,  INABA TAKASHI

IPC: C07C311/16 ,  C07D217/02 ,  C07D217/10 ,  C07D401/12 ,  C07D401/14 ,  C07D405/12 ,  C07D409/12 ,  C07D491/10 ,  C07D401/00 ,  C07D413/00

Abstract: Novel quinoline sulfonamino derivatives having a vessel smooth muscle relaxation activity as well as a platelet agglutination inhibitory activity and inhibitory activity to protein kinase A, myosin light chain kinase, proteinkinase C, and calmodulindependent proteinkinase II, but having little action or cardio function; a process for the production of the derivatives, and a pharmaceutical composition containing the derivative.

公开(公告)号：CA2013432A1

公开(公告)日：1990-10-10

申请号：CA2013432

申请日：1990-03-29

Applicant: KIMURA MASAYASU ,  NAITO KENJI ,  SAKUMA OSAMU ,  MORITA TADASHI

Inventor： KIMURA MASAYASU ,  NAITO KENJI ,  SAKUMA OSAMU ,  MORITA TADASHI

IPC: A61K31/14 ,  A61K31/215 ,  A61P21/02 ,  C07C43/174 ,  C07C45/41 ,  C07C57/34 ,  C07C57/40 ,  C07C69/612 ,  C07C69/618 ,  C07C205/11 ,  C07C209/12 ,  C07C211/27 ,  C07C211/28 ,  C07C211/29 ,  C07C211/30 ,  C07C211/49 ,  C07C211/63 ,  C07C215/18 ,  C07C215/30 ,  C07C215/40 ,  C07C217/10 ,  C07C217/20 ,  C07C219/22 ,  C07C225/06 ,  C07C225/16 ,  C07C227/18 ,  C07C229/34 ,  C07C229/38 ,  C07C231/12 ,  C07C233/43 ,  C07C317/28 ,  C07C323/25 ,  C07C323/62 ,  C07D213/06 ,  C07D213/16 ,  C07D295/02 ,  C07D295/135 ,  C07D309/12 ,  C07D339/08 ,  A61K31/245 ,  C07C323/32 ,  C07C217/48 ,  C07C323/63

Abstract: A guaternary ammonium compound having a muscle relaxation activity represented by the formula (I): wherein R1 represents a methylene, a lower alkylenoxy, a lower alkenylene, a lower alkynylene, -CO-, -COO-, a lower alkylene carbonyloxy, -CH(OR5)-, a lower alkylenecarbonyl, a hydroxy lower alkylene, -O-, -S-, -SO-, or -SO2-; R2 represents a hydrogen atom, a hydroxy lower alkyl, an aldehyde, a lower alkyl carbonyl, -NO2 , or -NHR6; R3 represents a hydrogen atom of a group -R1,(CH2)a-¢CH(CH2A)-CH2!b-A; R4 represents an anion; R5 and R6 represent a hydrogen atom or a acetyl; A represents a quaternary ammonium group; a represents an integer of 1 to 8; b represents 0 or 1; m represents an integer of 1 to 4; and (Z) represents a trivalent benzene ring, a trivalent naphthalene ring, a trivalent diphenyl or a trivalent ethane radical.

公开(公告)号：JPH10333809A

公开(公告)日：1998-12-18

申请号：JP13827797

申请日：1997-05-28

Applicant: SAKUMA OSAMU

Inventor： SAKUMA OSAMU

IPC: G09B21/00 ,  G06F3/02 ,  G06F3/16 ,  G10L13/04 ,  H04M11/00 ,  G10L5/02

Abstract: PROBLEM TO BE SOLVED: To provide a character inputting and voice converting device that can perform voice conversation with a communicating party only by a key operation without the generation of any noise sound in the surroundings, and a portable telephone equipped with the device. SOLUTION: This converting device is provided with less than 20 keys for transmitting vowels (A, I, U, E, O), the basic articulation of KA-line, SA-line, TA-line, NA-line, HA-line, MA-line, YA-line, RA-line, WA-line, BA-line, DA-line, GA-line, PA-line, and ZA-lione, and the composite basic articulation of KYA-line, GYA-line, BYA-line, PYA-line, NYA-line, HYA-line, MYA-line, RYA-line, JYA- line, CHA-line, and SYA-line by the inputting operation of alphanumeric character keys from one time to three times. Moreover, this device is provided with a voice converting means for transmitting a long vowel and a consonant by the key operation.

公开(公告)号：JPH117222A

公开(公告)日：1999-01-12

申请号：JP19471497

申请日：1997-06-16

Applicant: SAKUMA OSAMU

Inventor： SAKUMA OSAMU

IPC: G03G21/00

Abstract: PROBLEM TO BE SOLVED: To confirm a copied result in advance which was unable to predicted by a conventional copying machine through an external monitor by utilizing a CCD. SOLUTION: An original is irradiated with light and the image thereof is transmitted to the CCD through a lens. The image of an electric signal converted by the CCD is received by the monitor installed outside the copying machine. Thus, the position of the original can be adjusted and magnification can be changed. Besides, a copying paper and toner are prevented from being wastefully consumed.