公开(公告)号：WO2013054472A3

公开(公告)日：2013-07-18

申请号：PCT/JP2012005937

申请日：2012-09-18

Applicant: SONY CORP ,  WADA SEIJI ,  NAKAMURA MITSUHIRO ,  KIMURA NATSUKI ,  SOMA HARUHIKO ,  NAKASHIMA YUSAKU ,  YAMAMOTO TAKURO ,  TOMITA TAKASHI

Inventor： WADA SEIJI ,  NAKAMURA MITSUHIRO ,  KIMURA NATSUKI ,  SOMA HARUHIKO ,  NAKASHIMA YUSAKU ,  YAMAMOTO TAKURO ,  TOMITA TAKASHI

IPC: A61B5/0478

CPC classification number: A61B5/6803 ,  A61B5/0478 ,  A61B5/08 ,  A61B5/14542 ,  A61B2560/045 ,  A61B2562/12

Abstract: To provide a headband capable of correctly placing an electrode on a head of a user, a headband apparatus includes a plurality of headband portions integrally connected and configured to be positioned about a head of a user, wherein at least two headband portions are each configured to be positioned behind an ear.

Abstract translation: 为了提供一种能够将电极正确地放置在用户头部上的头带，一种头带装置包括多个头带部分，所述多个头带部分整体连接并且被配置为定位在用户的头部周围，其中至少两个头带部分均被配置为 置于耳后。

公开(公告)号：DE60329384D1

公开(公告)日：2009-11-05

申请号：DE60329384

申请日：2003-05-21

Applicant: SONY CORP

Inventor： MAMINE TAKAYOSHI ,  YAMAMOTO TAKURO

IPC: G01N33/53 ,  C12Q1/68 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14 ,  G01N33/543 ,  G01N37/00

Abstract: Disclosed is a bioassay method in which, by controlling the electric field formation in the reaction region where an interaction between substances, such as a hybridization, is performed, the efficiency of the interaction can be improved. Also disclosed is a bioassay apparatus in which the method can be favorably carried out. In the method, an interaction between substances is detected by a detecting element 1 (10), the detecting element including at least a detection surface S (S') which is surface-treated for immobilizing a detecting substance D, a reaction region R (R') which provides a field for interaction between the detecting substance D immobilized on the detection surface S (S') and a target substance T, and an electric field-forming means E which forms an electric field in the reaction region R (R') by applying a potential difference in the reaction region R (R'), and the method includes at least a step of turning on/off the electric field formation by the electric field-forming means E at a predetermined timing.

公开(公告)号：DE602008000125D1

公开(公告)日：2009-10-15

申请号：DE602008000125

申请日：2008-02-01

Applicant: SONY CORP

Inventor： YAMAMOTO TAKURO ,  ABE TOMOTERU ,  NAKAGAWA KAZUHIRO ,  YAMASHITA SHIKO ,  SOMA HARUHIKO ,  KISHII NORIYUKI

IPC: A61B10/02 ,  A45D26/00 ,  A61B10/00 ,  A61B17/00 ,  A61B19/00

公开(公告)号：AU2003235387A1

公开(公告)日：2003-12-02

申请号：AU2003235387

申请日：2003-05-21

Applicant: SONY CORP

Inventor： MAMINE TAKAYOSHI ,  YAMAMOTO TAKURO

IPC: C12Q1/68 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14 ,  G01N33/543 ,  G01N33/53 ,  G01N37/00

Abstract: Disclosed is a bioassay method in which, by controlling the electric field formation in the reaction region where an interaction between substances, such as a hybridization, is performed, the efficiency of the interaction can be improved. Also disclosed is a bioassay apparatus in which the method can be favorably carried out. In the method, an interaction between substances is detected by a detecting element 1 (10), the detecting element including at least a detection surface S (S') which is surface-treated for immobilizing a detecting substance D, a reaction region R (R') which provides a field for interaction between the detecting substance D immobilized on the detection surface S (S') and a target substance T, and an electric field-forming means E which forms an electric field in the reaction region R (R') by applying a potential difference in the reaction region R (R'), and the method includes at least a step of turning on/off the electric field formation by the electric field-forming means E at a predetermined timing.

公开(公告)号：EP2172925A4

公开(公告)日：2010-09-22

申请号：EP08791817

申请日：2008-07-29

Applicant: SONY CORP

Inventor： YAMAMOTO TAKURO ,  YAMASHITA SHIKO ,  YASUDA AKIO ,  SHIONO MAYUMI ,  KISHII NORIYUKI ,  NAKAGAWA KAZUHIRO ,  HAYAKAWA TOMOHIRO

IPC: G09G5/02 ,  G02F1/13 ,  G09F9/00 ,  G09G3/20 ,  G09G3/30 ,  G09G3/32 ,  G09G3/34 ,  G09G5/14 ,  H01L51/50

CPC classification number: G09G3/3413 ,  G02F1/1336 ,  G09G3/3208 ,  G09G5/14 ,  G09G2320/0666 ,  G09G2320/0686

公开(公告)号：EP1507146A4

公开(公告)日：2005-08-24

申请号：EP03752936

申请日：2003-05-21

Applicant: SONY CORP

Inventor： MAMINE TAKAYOSHI ,  YAMAMOTO TAKURO

IPC: C12Q1/68 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14 ,  G01N33/543 ,  G01N33/53 ,  G01N37/00

CPC classification number: G01N33/543 ,  B01J2219/0036 ,  B01J2219/00362 ,  B01J2219/00378 ,  B01J2219/00527 ,  B01J2219/00536 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00653 ,  B01J2219/00659 ,  B01J2219/00677 ,  B01J2219/00722 ,  B01J2219/00725 ,  C40B40/06 ,  C40B40/10 ,  C40B60/14 ,  G01N33/54366 ,  G01N33/54373 ,  G01N33/54393

Abstract: A bioassay method in which the efficiency of an interaction between substances such as hybridization is enhanced by controlling the production of an electric field in a reaction region where the interaction occurs, and a bioassay device for preferably implementing the method are disclosed. The method is conducted to detect an interaction between substances by using a detector (1(10)) at least having a detection surface (S(S')) subjected to a surface treatment for fixing a substance D for detection, a reaction region (R(R')) for providing a field where an interaction between the detection substance D fixed to the detection surface (S(S')) and an added target substance T occurs, and electric field producing means (E) for producing an electric field in the reaction region (R(R')) by causing a potential difference in the reaction region (R(R')). The method comprises a procedure of turning on/off the electric field producing means (E) at a predetermined timing so as to produce/extinguish an electric field.

公开(公告)号：EP2767235A4

公开(公告)日：2015-07-08

申请号：EP12839788

申请日：2012-09-26

Applicant: SONY CORP

Inventor： WADA SEIJI ,  YAMAMOTO TAKURO ,  SOMA HARUHIKO ,  NAKASHIMA YUSAKU ,  TOMITA TAKASHI ,  NAKAMURA MITSUHIRO ,  KIMURA NATSUKI

IPC: A61B5/16 ,  A61B5/0402 ,  A61B5/0408 ,  A61B5/0476 ,  A61B5/0478 ,  A61B5/0488 ,  A61B5/087 ,  A61B5/11 ,  A61B5/113 ,  A61B5/1455

CPC classification number: A61B5/0006 ,  A61B5/0205 ,  A61B5/04012 ,  A61B5/0402 ,  A61B5/0408 ,  A61B5/0478 ,  A61B5/0496 ,  A61B5/087 ,  A61B5/1135 ,  A61B5/14542 ,  A61B5/4806 ,  A61B5/4812 ,  A61B5/4818 ,  A61B5/6803 ,  A61B2562/06

公开(公告)号：EP1864997A4

公开(公告)日：2009-02-25

申请号：EP06730113

申请日：2006-03-27

Applicant: SONY CORP

Inventor： YAMAMOTO TAKURO ,  MAMINE TAKAYOSHI ,  TAKUMI TORU ,  AKASHI MAKOTO

IPC: C07K14/47 ,  A61K31/7088 ,  A61K31/7105 ,  A61K39/395 ,  A61K45/00 ,  A61K48/00 ,  A61P25/00 ,  A61P25/20 ,  A61P35/00 ,  C12M1/00 ,  C12N15/09 ,  C12Q1/02 ,  G01N33/15 ,  G01N33/50 ,  G01N33/53 ,  G01N33/566

CPC classification number: A61K31/7105 ,  A61K31/7088 ,  C07K14/4702 ,  C07K14/70567 ,  G01N33/743 ,  G01N2333/70567 ,  G01N2500/00

Abstract: It is intended to clarify the undisclosed part of the mechanism controlling the circadian rhythm. It is newly found out that RORa (retinoic acid binding-receptor alpha, the same applies hereinafter) promotes the induction of Bmal1 expression and that the induction of Bmal1 expression is promoted under hypoxic conditions. These facts strongly suggest the presence of the mechanism controlling the circadian rhythm wherein, when RORa expression is promoted under hypoxic conditions etc., the induction of Bmal1 expression is promoted and the promotion of the induction of Bmal1 expression promotes the binding of BMAL1 to CLOCK to thereby promote the induction of the expression of the Per gene or the Cry gene. Accordingly, the above findings are likely applicable to agents for regulating jet lag and anticancer drugs.

公开(公告)号：EP2175035A4

公开(公告)日：2010-11-17

申请号：EP08791203

申请日：2008-07-16

Applicant: SONY CORP

Inventor： YAMAMOTO TAKURO ,  AKASHI MAKOTO ,  YAMASHITA SHIKO ,  ABE TOMOTERU ,  NAKAGAWA KAZUHIRO ,  SOMA HARUHIKO ,  NODE KOICHI ,  KISHII NORIYUKI ,  HAYAKAWA TOMOHIRO

IPC: C12Q1/68 ,  C12N15/09

CPC classification number: C12Q1/6881 ,  C12Q1/6876 ,  C12Q2600/158

公开(公告)号：EP1908849A4

公开(公告)日：2009-03-04

申请号：EP06781776

申请日：2006-07-27

Applicant: SONY CORP

Inventor： NAKAMURA RYOTA ,  KISHII NORIYUKI ,  ABE TOMOTERU ,  YAMAMOTO TAKURO ,  YAMASHITA SHIKO ,  SEGAWA YUJI ,  OMORI SHINJI

IPC: C12Q1/68 ,  C12N15/09

CPC classification number: C12Q1/6832 ,  C12Q1/6837 ,  C12Q2563/173 ,  C12Q2527/101 ,  C12Q2521/307 ,  C12Q2527/107 ,  C12Q2523/307

Abstract: The object is to increase the S/N ratio in the detection of the occurrence of hybridization to increase the detection accuracy. Disclosed is a hybridization detection method, in which the hybridization between a probe nucleic acid chain with a target nucleic acid chain is allowed to proceed in a reaction system, and then the temperature of the reaction system where the hybridization proceeds is raised to a temperature higher than a predetermined temperature, thereby increasing the S/N ratio in the detection of the hybridization.