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公开(公告)号：BR112021011564A2
公开(公告)日：2021-08-31
申请号：BR112021011564
申请日：2019-12-17
Applicant: VERTEX PHARMA
Inventor： MEDEK ALES , FORTIER ANNE , LEDFORD BRIAN , SAYEGH CAMIL , ELAINE B KRUEGER , WITKOS FAITH , DENIS FRANCOIS , CAO JINGRONG , JON H COME , HU KAN-NIAN , GAGNON KEVIN , LESLIE A DAKIN , HAMEL MARTINE , BRODNEY MICHAEL , SHRESTHA MUNA , NICOLAS OLIVIER , ROSE PETER , SUGANTHINI S NANTHAKUMAR , WANG TIANSHENG , TIMOTHY J SENTER , WARREN A DORSCH , SHI YI
IPC: C07D403/12 , A61K31/4025 , A61P13/12
Abstract: inibidores de apol1 e métodos de uso dos mesmos. trata-se de pelo menos uma entidade escolhida dentre os compostos de fórmula (i), formas de estado sólido dos mesmos, composições que compreendem os mesmos e métodos para usar os mesmos, incluindo o uso no tratamento de glomeruloesclerose segmentar focal (gesf) e/ou doença renal não diabética (ndkd).
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公开(公告)号：JOP20210130A1
公开(公告)日：2023-01-30
申请号：JOP20210130
申请日：2019-12-17
Applicant: VERTEX PHARMA
Inventor： SHI YI , MEDEK ALES , BRODNEY MICHAEL , DAKIN LESLIE A , DORSCH WARREN A , DENIS FRANCOIS , ROSE PETER , SENTER TIMOTHY J , SHRESTHA MUNA , SAYEGH CAMIL , GAGNON KEVIN , FORTIER ANNE , CAO JINGRONG , KRUEGER ELAINE B , COME JON H , LEDFORD BRIAN , NANTHAKUMAR SUGANTHINI S , NICOLAS OLIVIER , HAMEL MARTINE , HU KAN-NIAN , WANG TIANSHENG , WITKOS FAITH
Abstract: غيرمتوفر
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公开(公告)号：CR20210383A
公开(公告)日：2021-09-22
申请号：CR20210383
申请日：2019-12-17
Applicant: VERTEX PHARMA
Inventor： NANTHAKUMAR SUGANTHINI S , GAGNON KEVIN , DAKIN LESLIE A , HU KAN-NIAN , MEDEK ALES , SHI YI , SHRESTHA MUNA , DENIS FRANCOIS , KRUEGER ELAINE B , WITKOS FAITH , CAO JINGRONG , HAMEL MARTINE , LEDFORD BRIAN , NICOLAS OLIVIER , COME JON H , DORSCH WARREN A , FORTIER ANNE , ROSE PETER , SAYEGH CAMIL , WANG TIANSHENG , BRODNEY MICHAEL , SENTER TIMOTHY J
IPC: A61K31/4025 , A61P13/12 , C07D403/12
Abstract: La descripción proporciona al menos una entidad seleccionada de compuestos de la fórmula ( I ), formas en estado sólido de ellos, composiciones que los comprenden y métodos que los usan, incluyendo el uso en el tratamiento de glomeruloesclerosis segmentaria focal (FSGS) y/o enfermedad renal no diabética (NDKD).
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公开(公告)号：MA54538A
公开(公告)日：2021-10-27
申请号：MA54538
申请日：2019-12-17
Applicant: VERTEX PHARMA
Inventor： BRODNEY MICHAEL , CAO JINGRONG , COME JON H , DAKIN LESLIE A , DENIS FRANCOIS , DORSCH WARREN A , FORTIER ANNE , GAGNON KEVIN , HAMEL MARTINE , HU KAN-NIAN , KRUEGER ELAINE B , LEDFORD BRIAN , MEDEK ALES , NANTHAKUMAR SUGANTHINI S , NICOLAS OLIVIER , ROSE PETER , SAYEGH CAMIL , SENTER TIMOTHY J , SHI YI , SHRESTHA MUNA , WANG TIANSHENG , WITKOS FAITH
IPC: A61K31/4025 , A61P13/12 , C07D403/12
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公开(公告)号：UY38514A
公开(公告)日：2020-07-31
申请号：UY38514
申请日：2019-12-17
Applicant: VERTEX PHARMA
Inventor： SHI YI , SHRESTHA MUNA , BRODNEY MICHAEL , CAO JINGRONG , JON H COME , LESLIE A DAKIN , DENIS FRANCOIS , WARREN A DORSCH , FORTIER ANNE , GAGNON KEVIN , HAMEL MARTINE , KAN-NIAN HU , ELAINE B KRUEGER , LEDFORD BRIAN , MEDEK ALES , SUGANTHINI S NANTHAKUMAR , NICOLAS OLIVIER , ROSE PETER , SAYEGH CAMIL , TIMOTHY J SENTER , WANG TIANSHENG , WITKOS FAITH
IPC: A61P13/12 , A61K31/404 , C07D403/12 , C07D405/14
Abstract: La descripción proporciona al menos una entidad seleccionada de compuestos de la fórmula (I), formas en estado sólido de ellos, composiciones que los comprenden y métodos que los usan, incluyendo el uso en el tratamiento de glomeruloesclerosis segmentaria focal (FSGS) y/o enfermedad renal no diabética (NDKD).
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Patent Agency Ranking
公开(公告)号：CA3121910A1
公开(公告)日：2020-06-25
申请号：CA3121910
申请日：2019-12-17
Applicant: VERTEX PHARMA
Inventor： BRODNEY MICHAEL , GAGNON KEVIN , HU KAN-NIAN , MEDEK ALES , ROSE PETER , SHI YI , SHRESTHA MUNA , WITKOS FAITH , CAO JINGRONG , COME JON H , DAKIN LESLIE A , DENIS FRANCOIS , DORSCH WARREN A , FORTIER ANNE , HAMEL MARTINE , KRUEGER ELAINE B , LEDFORD BRIAN , NANTHAKUMAR SUGANTHINI S , NICOLAS OLIVIER , SAYEGH CAMIL , SENTER TIMOTHY J , WANG TIANSHENG
IPC: A61K31/405 , A61P13/12 , C07D403/12
Abstract: The disclosure provides at least one entity chosen from compounds of formula (I), solid state forms of the same, compositions comprising the same, and methods of using the same, including use in treating focal segmental glomerulosclerosis (FSGS) and/or non-diabetic kidney disease (NDKD).
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公开(公告)号：UA128375C2
公开(公告)日：2024-06-26
申请号：UAA202104153
申请日：2019-12-17
Applicant: VERTEX PHARMA
Inventor： BRODNEY MICHAEL , GAGNON KEVIN , HU KAN-NIAN , MEDEK ALES , ROSE PETER , SHI YI , SHRESTHA MUNA , WITKOS FAITH , CAO JINGRONG , COME JON H , DAKIN LESLIE A , DENIS FRANCOIS , DORSCH WARREN A , FORTIER ANNE , HAMEL MARTINE , KRUEGER ELAINE B , LEDFORD BRIAN , NANTHAKUMAR SUGANTHINI S , NICOLAS OLIVIER , SAYEGH CAMIL , SENTER TIMOTHY J , WANG TIANSHENG
Abstract: Увинаходізапропонованащонайменшеоднасполука, вибраназісполукформули (I), їїтвердофазніформи, щомістятьїїкомпозиціїтаспособиїїзастосування, втомучисліприлікуванніфокально-сегментарногогломерулосклерозу (ФСГС) і/абонедіабетичногозахворюваннянирок (НДЗН). 323
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公开(公告)号：JOP20210129A1
公开(公告)日：2023-01-30
申请号：JOP20210129
申请日：2019-12-17
Applicant: VERTEX PHARMA
Inventor： SHI YI , MEDEK ALES , BRODNEY MICHAEL , DAKIN LESLIE A , DORSCH WARREN A , DENIS FRANCOIS , ROSE PETER , SENTER TIMOTHY J , SHRESTHA MUNA , SAYEGH CAMIL , GAGNON KEVIN , FORTIER ANNE , CAO JINGRONG , KRUEGER ELAINE B , COME JON H , LEDFORD BRIAN , NANTHAKUMAR SUGANTHINI S , NICOLAS OLIVIER , HAMEL MARTINE , HU KAN-NIAN , WANG TIANSHENG , WITKOS FAITH
Abstract: غيرمتوفر
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公开(公告)号：AU2021213758A1
公开(公告)日：2022-09-01
申请号：AU2021213758
申请日：2021-01-28
Applicant: VERTEX PHARMA
Inventor： CAO JINGRONG , COME JON H , DAKIN LESLIE A , DENIS FRANCOIS , DORSCH WARREN A , FORTIER ANNE , HAMEL MARTINE , KRUEGER ELAINE B , LEDFORD BRIAN , MALTAIS FRANCOIS , NANTHAKUMAR SUGANTHINI S , NICOLAS OLIVIER , SAYEGH CAMIL E , SENTER TIMOTHY J , WANG TIANSHENG
IPC: C07D209/12 , A61K31/404 , A61P13/12 , C07D209/18 , C07D401/12 , C07D403/12 , C07D407/12 , C07D413/12
Abstract: The disclosure provides at least one entity chosen from compounds of Formula (I) pharmaceutically acceptable salts thereof, solvates of any of the foregoing, and deuterated derivatives of any of the foregoing, compositions comprising the same, and methods of using the same, including use in treating APOL1 mediated kidney disease.
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公开(公告)号：MX2021007152A
公开(公告)日：2021-11-03
申请号：MX2021007152
申请日：2019-12-17
Applicant: VERTEX PHARMA
Inventor： LEDFORD BRIAN , WANG TIANSHENG , SHI YI , COME JON H , MEDEK ALES , SHRESTHA MUNA , BRODNEY MICHAEL , GAGNON KEVIN , HU KAN - NIAN , ROSE PETER , WITKOS FAITH , CAO JINGRONG , DAKIN LESLIE A , DENIS FRANCOIS , DORSCH WARREN A , FORTIER ANNE , HAMEL MARTINE , KRUEGER ELAINE B , NANTHAKUMAR SUGANTHINI S , NICOLAS OLIVIER , SAYEGH CAMIL , SENTER TIMOTHY J
IPC: A61P13/12 , A61K31/4025 , C07D403/12
Abstract: La descripción proporciona al menos una entidad seleccionada de compuestos de la fórmula (I), formas en estado sólido de ellos, composiciones que los comprenden y métodos que los usan, incluyendo el uso en el tratamiento de glomeruloesclerosis segmentaria focal (FSGS) y/o enfermedad renal no diabética (NDKD).
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