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公开(公告)号：HRP20241695T1
公开(公告)日：2025-02-14
申请号：HRP20241695
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
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公开(公告)号：PL4069691T3
公开(公告)日：2025-01-27
申请号：PL20825397
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
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公开(公告)号：SI4069691T1
公开(公告)日：2025-02-28
申请号：SI202030535
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
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Patent Agency Ranking
公开(公告)号：CO2022008969A2
公开(公告)日：2022-09-09
申请号：CO2022008969
申请日：2022-06-28
Applicant: VERTEX PHARMA
Inventor： AHMAD NADIA , SCHMIDT YVONNE , THOMSON STEPHEN ANDREW , DURRANT STEVEN JOHN , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
Abstract: Se proporcionan compuestos y sus sales farmacéuticamente aceptables, de utilidad como inhibidores de canales de sodio. También se proporcionan composiciones farmacéuticas que comprenden los compuestos o sales farmacéuticamente aceptables y métodos de uso de los compuestos, sales farmacéuticamente aceptables y composiciones farmacéuticas en el tratamiento de diversos trastornos, incluyendo el dolor.
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公开(公告)号：MD4069691T2
公开(公告)日：2025-03-31
申请号：MDE20221109
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
Abstract: Sunt furnizaţi compuşi şi săruri acceptabile farmaceutic ale acestora, utile ca inhibitori ai canalelor de sodiu. Sunt de asemenea furnizate compoziţii farmaceutice care cuprind compuşii sau sărurile acceptabile farmaceutic şi metode de utilizare a compuşilor, sărurilor acceptabile farmaceutic şi compoziţiilor farmaceutice ȋn tratarea a diferite tulburări, incluzând durere.
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公开(公告)号：RS66307B1
公开(公告)日：2025-01-31
申请号：RSP20241330
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
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公开(公告)号：SMT202400488T1
公开(公告)日：2025-01-14
申请号：SMT202400488
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： HADIDA RUAH SARA S , DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
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公开(公告)号：AU2020397059A1
公开(公告)日：2022-07-21
申请号：AU2020397059
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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