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公开(公告)号：HRP20241695T1
公开(公告)日：2025-02-14
申请号：HRP20241695
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
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公开(公告)号：PL4069691T3
公开(公告)日：2025-01-27
申请号：PL20825397
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
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公开(公告)号：CO2024015816A2
公开(公告)日：2024-11-28
申请号：CO2024015816
申请日：2024-11-21
Applicant: VERTEX PHARMA
Inventor： HADIDA RUAH SARA SABINA , MCCARTNEY JASON , MILLER MARK THOMAS , ZHOU JINGLAN , PATEL URVI , CHUDYK EWA IWONA , HURLEY DENNIS JAMES , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , DEMORET ROBERT MARTIN , VALIULIN ROMAN ASKATOVICH , KINTZER ALEXANDER FREDERIK , SLOCHOWER DAVID ROBERT , AERTGEERTS KATHLEEN , BECK ELIZABETH MARY , KNEGTEL RONALD MARCELLUS ALPHONSUS , NESAN SAVARIAR ELAMPRAKASH , WEBB PETER , GULEVICH ANTON V , ISHIHARA YOSHIHIRO , TRAN JOE A , SCHARF ADAM
IPC: A61P9/06 , A61K31/4375 , A61K31/47 , A61P25/02 , A61P29/00 , C07D215/233 , C07D401/04 , C07D471/04 , C07D519/00
Abstract: Se proporcionan compuestos, y sales farmacéuticamente aceptables de estos, útiles como inhibidores de canales de sodio. También se proporcionan composiciones farmacéuticas que comprenden los compuestos o sales farmacéuticamente aceptables y métodos de uso de los compuestos, sales farmacéuticamente aceptables y composiciones farmacéuticas en el tratamiento de diversos trastornos, incluido el dolor.
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公开(公告)号：SI4069691T1
公开(公告)日：2025-02-28
申请号：SI202030535
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
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公开(公告)号：MD4069691T2
公开(公告)日：2025-03-31
申请号：MDE20221109
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
Abstract: Sunt furnizaţi compuşi şi săruri acceptabile farmaceutic ale acestora, utile ca inhibitori ai canalelor de sodiu. Sunt de asemenea furnizate compoziţii farmaceutice care cuprind compuşii sau sărurile acceptabile farmaceutic şi metode de utilizare a compuşilor, sărurilor acceptabile farmaceutic şi compoziţiilor farmaceutice ȋn tratarea a diferite tulburări, incluzând durere.
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Patent Agency Ranking
公开(公告)号：RS66307B1
公开(公告)日：2025-01-31
申请号：RSP20241330
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
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公开(公告)号：SMT202400488T1
公开(公告)日：2025-01-14
申请号：SMT202400488
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： HADIDA RUAH SARA S , DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
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公开(公告)号：IL316462A
公开(公告)日：2024-12-01
申请号：IL31646224
申请日：2024-10-21
Applicant: VERTEX PHARMA , MILLER MARK THOMAS , HURLEY DENNIS JAMES , NEUBERT TIMOTHY DONALD , ARUMUGAM VIJAYALAKSMI , HADIDA RUAH SARA SABINA , MCCARTNEY JASON , ZHOU JINGLAN , CHAU JACLYN , DEMORET ROBERT MARTIN , GHIRMAI SENAIT G , VALIULIN ROMAN ASKATOVICH , KINTZER ALEXANDER FREDERIK , SLOCHOWER DAVID ROBERT , AERTGEERTS KATHLEEN , BECK ELIZABETH MARY , MUI JAMES JUN BON , WRIGHT MIRANDA ADELE , KNEGTEL RONALD MARCELLUS ALPHONSUS , CHUDYK EWA IWONA , PINDER JOANNE LOUISE , DODD JAMES , SIMPSON IAIN
Inventor： MILLER MARK THOMAS , HURLEY DENNIS JAMES , NEUBERT TIMOTHY DONALD , ARUMUGAM VIJAYALAKSMI , HADIDA RUAH SARA SABINA , MCCARTNEY JASON , ZHOU JINGLAN , CHAU JACLYN , DEMORET ROBERT MARTIN , GHIRMAI SENAIT G , VALIULIN ROMAN ASKATOVICH , KINTZER ALEXANDER FREDERIK , SLOCHOWER DAVID ROBERT , AERTGEERTS KATHLEEN , BECK ELIZABETH MARY , MUI JAMES JUN BON , WRIGHT MIRANDA ADELE , KNEGTEL RONALD MARCELLUS ALPHONSUS , CHUDYK EWA IWONA , PINDER JOANNE LOUISE , DODD JAMES , SIMPSON IAIN
Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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公开(公告)号：IL316422A
公开(公告)日：2024-12-01
申请号：IL31642224
申请日：2024-10-16
Applicant: VERTEX PHARMA , MILLER MARK THOMAS , HURLEY DENNIS JAMES , NEUBERT TIMOTHY DONALD , NESAN SAVARIAR ELAMPRAKASH , PATEL URVI , HADIDA RUAH SARA SABINA , MCCARTNEY JASON , ZHOU JINGLAN , DEMORET ROBERT MARTIN , VALIULIN ROMAN ASKATOVICH , KINTZER ALEXANDER FREDERIK , WEBB PETER , SLOCHOWER DAVID ROBERT , AERTGEERTS KATHLEEN , BECK ELIZABETH MARY , KNEGTEL RONALD MARCELLUS ALPHONSUS , CHUDYK EWA IWONA , PINDER JOANNE LOUISE , GULEVICH ANTON V , ISHIHARA YOSHIHIRO , TRAN JOE A , SCHARF ADAM
Inventor： MILLER MARK THOMAS , HURLEY DENNIS JAMES , NEUBERT TIMOTHY DONALD , NESAN SAVARIAR ELAMPRAKASH , PATEL URVI , HADIDA RUAH SARA SABINA , MCCARTNEY JASON , ZHOU JINGLAN , DEMORET ROBERT MARTIN , VALIULIN ROMAN ASKATOVICH , KINTZER ALEXANDER FREDERIK , WEBB PETER , SLOCHOWER DAVID ROBERT , AERTGEERTS KATHLEEN , BECK ELIZABETH MARY , KNEGTEL RONALD MARCELLUS ALPHONSUS , CHUDYK EWA IWONA , PINDER JOANNE LOUISE , GULEVICH ANTON V , ISHIHARA YOSHIHIRO , TRAN JOE A , SCHARF ADAM
Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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公开(公告)号：AU2020397059A1
公开(公告)日：2022-07-21
申请号：AU2020397059
申请日：2020-12-04
Applicant: VERTEX PHARMA
Inventor： DURRANT STEVEN JOHN , AHMAD NADIA , BECK ELIZABETH MARY , CARVALHO MEIRELES LIDIO , CHUDYK EWA IWONA , ETXEBARRIA JARDI GORKA , GALAN BHAIRAVI , HADIDA RUAH SARA S , HURLEY DENNIS JAMES , KNEGTEL RONALD MARCELLUS , NEUBERT TIMOTHY DONALD , PINDER JOANNE LOUISE , PONTILLO JOSEPH , PULLIN ROBERT , SCHMIDT YVONNE , SHAW DAVID MATTHEW , SKERRATT SARAH , STAMOS DEAN , THOMSON STEPHEN ANDREW , VIRANI ANISA NIZARALI , WRAY CHRISTOPHER
IPC: C07D405/12 , A61K31/443 , A61P29/00 , C07D405/14
Abstract: Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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