公开(公告)号：US20230296508A1

公开(公告)日：2023-09-21

申请号：US18184019

申请日：2023-03-15

Applicant: KineoLabs

Inventor： Walid A. Atia ,  Dale C. Flanders

IPC: G01N21/39 ,  G01B9/02091

CPC classification number: G01N21/39 ,  G01B9/02091 ,  G01N2201/0633 ,  G01N2201/105 ,  G01N2201/06113

Abstract: A line field optical coherence tomography (OCT) system and an absorption spectrometer system employing a tunable or swept laser architecture. The laser is a cat's-eye configuration with a preferably transmissive tilt tuned interference thin film filter.

公开(公告)号：US11762180B2

公开(公告)日：2023-09-19

申请号：US16622542

申请日：2018-06-15

Applicant: UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS

Inventor： Kishan Dholakia

IPC: G02B21/00 ,  G01N21/64

CPC classification number: G02B21/0032 ,  G01N21/6458 ,  G01N21/6486 ,  G02B21/0076 ,  G01N2201/0633 ,  G01N2201/0634 ,  G01N2201/06113 ,  G01N2201/08 ,  G02B2207/114

Abstract: A light sheet imaging system, such as a light sheet microscope, comprises an illumination arrangement for generating a light sheet for three-photon excitation of a fluorescent sample, and a fluorescence collection arrangement for collecting fluorescence generated in the sample as a result of three-photon excitation by the light sheet. The light sheet may be a non-diffractive, propagation-invariant light sheet. The light sheet may be formed from and/or comprise a Bessel beam. A method of light sheet imaging comprises using a light sheet for three-photon excitation of a fluorescent sample, and collecting fluorescence generated in the sample as a result of three-photon excitation of the sample by the light sheet. Such a method may be used for light sheet microscopy.

公开(公告)号：US11662309B2

公开(公告)日：2023-05-30

申请号：US17396556

申请日：2021-08-06

Applicant: Opsolution GMBH

Inventor： Bjoern Magnussen ,  Claudius Stern ,  Wolfgang Koecher

IPC: G01N21/49 ,  A61B5/1455 ,  G01N21/47 ,  A61B5/145 ,  G01N21/17

CPC classification number: G01N21/49 ,  A61B5/1455 ,  A61B5/14546 ,  G01N21/474 ,  G01N21/4795 ,  A61B5/14532 ,  A61B2560/0223 ,  A61B2562/046 ,  G01N2021/1782 ,  G01N2021/4752 ,  G01N2201/066 ,  G01N2201/0621 ,  G01N2201/0626 ,  G01N2201/0633 ,  G01N2201/06153 ,  G01N2201/1211 ,  G01N2201/1214

Abstract: A device for optical detection of analytes in a sample includes at least two optoelectronic components. The optoelectronic components include at least one optical detector configured to receive a photon and at least one optical emitter configured to emit a photon. The at least one optical emitter includes at least three optical emitters disposed in a flat, non-linear arrangement, and the at least one optical detector includes at least three optical detectors disposed in a flat, non-linear arrangement. The at least three optical emitters and the at least three optical detectors include at least three different wavelength characteristics.

公开(公告)号：US20230152213A1

公开(公告)日：2023-05-18

申请号：US17967228

申请日：2022-10-17

Applicant: Samsung Electronics Co., Ltd.

Inventor： Yasuhiro HIDAKA

IPC: G01N21/21 ,  G02B5/30 ,  H01L21/67

CPC classification number: G01N21/211 ,  G02B5/3066 ,  G02B5/3083 ,  H01L21/67253 ,  G01N2201/0633

Abstract: An ellipsometer capable of improving a throughput calculating ellipsometry coefficients (ψ, Δ) even when performing measurement with a combination of a light source having a wide wavelength band and a spectrometer, and an apparatus for inspecting a semiconductor device is e hid g the ellipsometer may be provided. The ellipsometer includes a polarizing optical element unit for separating reflected light into two polarization components having polarization directions that are orthogonal to each other in a radial direction with respect to an optical axis of an optical system of the reflected light, an analyzer unit for transmitting components of a direction different from the polarization directions of the two polarization components to make the two polarization components interfere with each other, and to form an interference fringe in a form of a concentric circle, an image detector for detecting the interference fringe, and processing circuitry for calculating ellipsometry coefficients from the interference fringe.

公开(公告)号：US11644418B2

公开(公告)日：2023-05-09

申请号：US17409122

申请日：2021-08-23

Applicant: Hitachi High-Tech Corporation

Inventor： Kei Shimura ,  Mizuki Mohara ,  Kenji Aiko

IPC: G01N21/3581

CPC classification number: G01N21/3581 ,  G01N2201/064 ,  G01N2201/0633 ,  G01N2201/0636 ,  G01N2201/0638 ,  G01N2201/06113

Abstract: The present invention provides a far-infrared light source capable of reducing the shift in the location irradiated with far-infrared light even when the frequency of the far-infrared light changes. A far-infrared light source according to the present invention is configured so that the variation in the emission angle of far-infrared light in a nonlinear optical crystal when the frequency of the far-infrared light changes is substantially offset by the variation in the refractive angle of the far-infrared light at the interface between the nonlinear optical crystal and a prism when the frequency of the far-infrared light changes (see FIG. 8).

公开(公告)号：US20180364154A1

公开(公告)日：2018-12-20

申请号：US15625899

申请日：2017-06-16

Applicant: CANON USA INC. ,  THE GENERAL HOSPITAL CORPORATION

Inventor： Tzu-Yu Wu ,  Mitsuhiro Ikuta ,  Dongkyun Kang ,  Guillermo J. Tearney

IPC: G01N21/31 ,  G02B23/24 ,  G02B23/26

CPC classification number: G01N21/31 ,  A61B1/00096 ,  A61B1/00172 ,  A61B1/00186 ,  A61B1/063 ,  A61B1/0638 ,  A61B1/0646 ,  G01J3/0218 ,  G01J3/06 ,  G01J3/2823 ,  G01N2201/0633 ,  G01N2201/08 ,  G02B3/0087 ,  G02B6/00 ,  G02B23/2469 ,  G02B23/26 ,  G02B26/106 ,  G02B26/108

Abstract: An apparatus for spectrally encoded endoscopy (SEE) comprising an illumination element, a detection light guiding element, a rotary element, and a two-dimensional sensor. The illumination element is configured to direct an illumination light beam towards a sample. The detection light guiding element is configured to collect a reflected light beam from the sample. At least one of the illumination element and the detection light guiding element is configured to spectrally dispersed the illumination light beam or the reflected light beam, respectively. The rotary element is configured to rotate or oscillate the reflected light beam. The reflected light beam is guided from the rotary element to the two-dimensional sensor.

公开(公告)号：US20180348142A1

公开(公告)日：2018-12-06

申请号：US16054681

申请日：2018-08-03

Applicant: SamanTree Medical SA

Inventor： Bastien Rachet ,  Davor Kosanic ,  Etienne Shaffer

IPC: G01N21/77 ,  G02B21/36 ,  G01N21/64 ,  G02B21/26 ,  G02B21/34 ,  G01N33/483 ,  G02B21/00 ,  G02B21/16 ,  G02B21/24

CPC classification number: G01N21/77 ,  G01N21/6428 ,  G01N21/6458 ,  G01N33/4833 ,  G01N2021/6439 ,  G01N2021/6463 ,  G01N2021/7786 ,  G01N2201/0633 ,  G01N2201/068 ,  G02B21/0012 ,  G02B21/0032 ,  G02B21/004 ,  G02B21/0044 ,  G02B21/0076 ,  G02B21/0088 ,  G02B21/16 ,  G02B21/24 ,  G02B21/26 ,  G02B21/34 ,  G02B21/361

Abstract: The disclosed technology brings histopathology into the operating theatre, to enable real-time intra-operative digital pathology. The disclosed technology utilizes confocal imaging devices image, in the operating theatre, “optical slices” of fresh tissue—without the need to physically slice and otherwise process the resected tissue as required by frozen section analysis (FSA). The disclosed technology, in certain embodiments, includes a simple, operating-table-side digital histology scanner, with the capability of rapidly scanning all outer margins of a tissue sample (e.g., resection lump, removed tissue mass). Using point-scanning microscopy technology, the disclosed technology, in certain embodiments, precisely scans a thin “optical section” of the resected tissue, and sends the digital image to a pathologist rather than the real tissue, thereby providing the pathologist with the opportunity to analyze the tissue intra-operatively. Thus, the disclosed technology provides digital images with similar information content as FSA, but faster and without destroying the tissue sample itself.

公开(公告)号：US20180202926A1

公开(公告)日：2018-07-19

申请号：US15581153

申请日：2017-04-28

Applicant: CASCADE TECHNOLOGIES HOLDINGS LIMITED

Inventor： Paul BLACK ,  Ruth LINDLEY ,  Ian HOWIESON ,  Stephen WALDRON

IPC: G01N21/39 ,  G01N21/31

CPC classification number: G01N21/39 ,  G01N21/031 ,  G01N21/3151 ,  G01N21/3504 ,  G01N2021/399 ,  G01N2201/0612 ,  G01N2201/0633

Abstract: A laser detection system comprises a sample chamber configured to receive and contain a volume of sample gas, one or more lasers within at least one laser housing, wherein each laser is configured to produce a respective laser beam for excitation of one or more different materials in the sample gas and the one or more lasers are outside the sample chamber, a detector apparatus for detecting light output from the sample chamber, a first optical interface to the sample chamber having at least one window that is at least partially transparent to the laser beams from the one or more lasers, wherein the at least one laser housing is positioned in a close-coupling arrangement relative to the at least one window of the first optical interface such that, in use, the laser beams are substantially unmodified by passage between the laser housing and the at least one window.

公开(公告)号：US09989461B2

公开(公告)日：2018-06-05

申请号：US15200286

申请日：2016-07-01

Applicant: FUJI XEROX CO., LTD.

Inventor： Hiroyuki Hotta

IPC: G01D5/34 ,  G01N21/47

CPC classification number: G01N21/4785 ,  G01N21/4738 ,  G01N2021/4716 ,  G01N2201/0633 ,  G01N2201/0636 ,  G01N2201/0638

Abstract: A measuring device includes a light-emitting unit that radiates light onto an object, a first lens that changes a divergence degree of the light, a diaphragm having an aperture that reduces a diameter of the light, a second lens that converges and radiates the light onto the object, a light-receiving unit that receives at least part of the light that has been reflected by the object and that has passed through the second lens, a measuring unit that measures the object by using results related to the light-receiving unit, a reflector whose angle with respect to the light is adjustable, and a correction unit that varies a light-receiving position on the light-receiving unit by varying the reflector's angle and corrects a light amount of the light-emitting unit and a sensitivity of the light-receiving unit by using results obtained at each light-receiving position.

公开(公告)号：US09983125B2

公开(公告)日：2018-05-29

申请号：US14915473

申请日：2014-08-29

Applicant: Danmarks Tekniske Universitet

Inventor： Krzysztof Iwaszczuk ,  Peter Uhd Jepsen

IPC: G01J3/28 ,  G01N21/35 ,  H01L31/0232 ,  G01N21/3581

CPC classification number: G01N21/3581 ,  G01J3/28 ,  G01N2201/0633 ,  H01L31/0232

Abstract: The present invention relates to a system for detecting terahertz radiation, a camera device, and a method for detecting terahertz radiation.