公开(公告)号：US07190452B2

公开(公告)日：2007-03-13

申请号：US11058045

申请日：2005-02-14

Applicant: Haishan Zeng ,  Stephen Lam ,  Branko Mihael Palcic

Inventor： Haishan Zeng ,  Stephen Lam ,  Branko Mihael Palcic

IPC: G01J3/28

CPC classification number: G01J3/02 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0235 ,  G01J3/0243 ,  G01J3/0289 ,  G01J3/10 ,  G01J3/36 ,  G01N23/223 ,  G01N2223/076

Abstract: Optical systems that provide for simultaneous images and spectra from an object, such as a tissue sample, an industrial object such as a computer chip, or any other object that can be viewed with an optical system such as a microscope, endoscope, telescope or camera. In some embodiments, the systems provide multiple images corresponding to various desired wavelength ranges within an original image of the object, as well as, if desired, directional pointer(s) that can provide both an identification of the precise location from which a spectrum is being obtained, as well as enhancing the ability to point the device.

Abstract translation: 提供来自物体的同时图像和光谱的光学系统，例如组织样本，诸如计算机芯片的工业对象或可以用诸如显微镜，内窥镜，望远镜或照相机的光学系统观察的任何其它物体 。 在一些实施例中，系统提供对应于对象的原始图像内的各种期望波长范围的多个图像，以及如果需要的方向指针，其可以提供频谱的精确位置的识别 获得，以及增强指向设备的能力。

公开(公告)号：US20060268271A1

公开(公告)日：2006-11-30

申请号：US11085450

申请日：2005-03-22

Applicant: Martin Liphardt ,  Ping He

Inventor： Martin Liphardt ,  Ping He

IPC: G01J4/00

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0229 ,  G01J3/0243 ,  G01J4/00 ,  G01N21/211 ,  G02B17/008

Abstract: Low aberration relay systems modified to perform as spatial filters in reflectometer, spectrophotometer, ellipsometer, polarimeter and the like systems.

Abstract translation: 改进的低像差继电器系统作为反射计，分光光度计，椭偏仪，偏振计等系统中的空间滤波器。

公开(公告)号：US20060170919A1

公开(公告)日：2006-08-03

申请号：US11338276

申请日：2006-01-24

Applicant: Yoshifumi Takahashi ,  Takanori Saitoh ,  Kenichi Nakamura

Inventor： Yoshifumi Takahashi ,  Takanori Saitoh ,  Kenichi Nakamura

IPC: G01J3/28

CPC classification number: G01J3/28 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/021 ,  G01J3/0243 ,  G01J3/1804 ,  G01J2003/2866

Abstract: An optical spectrum analyzer measures to-be-measured light while carrying out calibration processing for correcting wavelength information of spectrum data of the to-be-measured light by a wavelength information correction device through a storage device based on the spectrum data of reference light that is obtained by causing the reference light whose wavelength is known to be incident on a tunable wavelength filter from light incident devices at all times together with the to-be-measured light. Since the optical spectrum analyzer can continuously measure the to-be-measured light in a wide wavelength range at high speed while maintaining high wavelength accuracy, it can continuously obtain the spectrum data of the to-be-measured light with high wavelength accuracy even if it is installed in a place in which an environment intensely changes.

Abstract translation: 光谱分析仪在进行基于参考光的频谱数据的基于光的参考光的频谱数据的波长信息校正装置进行用于校正待测光的光谱数据的波长信息的校准处理时， 通过使波长已知的参考光与待测光一起入射到可调谐波长滤光器上，并从光入射装置始终进入。 由于光谱分析仪可以在保持高波长精度的同时高速连续地测量宽波长范围内的被测光，所以即使在高频波长精度的情况下也可以连续获得待测光的光谱数据 它安装在环境剧烈变化的地方。

公开(公告)号：US20060001739A1

公开(公告)日：2006-01-05

申请号：US11154520

申请日：2005-06-17

Applicant: Noam Babayoff

Inventor： Noam Babayoff

IPC: H04N13/02 ,  H04N15/00

CPC classification number: H04N13/15 ,  A61B1/00009 ,  A61B1/00096 ,  A61B1/0615 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/0676 ,  A61B1/0684 ,  A61B1/24 ,  A61B1/247 ,  A61B5/0068 ,  A61B5/0088 ,  A61B5/1077 ,  A61B5/1079 ,  A61C9/0053 ,  A61C9/0066 ,  A61C19/04 ,  G01B11/24 ,  G01B11/25 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0218 ,  G01J3/0224 ,  G01J3/0243 ,  G01J3/0256 ,  G01J3/10 ,  G01J3/462 ,  G01J3/50 ,  G01J3/501 ,  G01J3/508 ,  G01J3/51 ,  G01N21/255 ,  G06F19/00 ,  G06T7/0012 ,  G06T7/12 ,  G06T7/90 ,  G06T2207/10024 ,  G06T2207/10028 ,  G06T2207/30036 ,  H01L27/14868 ,  H04N13/207 ,  H04N13/257 ,  H04N13/271 ,  H04N13/296

Abstract: A device for determining the surface topology and associated color of a structure, such as a teeth segment, includes a scanner for providing depth data for points along a two-dimensional array substantially orthogonal to the depth direction, and an image acquisition means for providing color data for each of the points of the array, while the spatial disposition of the device with respect to the structure is maintained substantially unchanged. A processor combines the color data and depth data for each point in the array, thereby providing a three-dimensional color virtual model of the surface of the structure. A corresponding method for determining the surface topology and associated color of a structure is also provided.

公开(公告)号：US20050203421A1

公开(公告)日：2005-09-15

申请号：US11053263

申请日：2005-02-07

Applicant: Haishan Zeng ,  Stephen Lam ,  Branko Palcic

Inventor： Haishan Zeng ,  Stephen Lam ,  Branko Palcic

IPC: G01N21/64 ,  A61B1/00 ,  A61B1/04 ,  G01J3/02 ,  G01J3/10 ,  G01J3/36 ,  G01N23/223 ,  G01N23/00 ,  A61B6/00 ,  G21K1/12 ,  H05G1/60

CPC classification number: G01J3/02 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/0235 ,  G01J3/0243 ,  G01J3/0289 ,  G01J3/10 ,  G01J3/36 ,  G01N23/223 ,  G01N2223/076

Abstract: Optical systems that provide for simultaneous images and spectra from an object, such as a tissue sample, an industrial object such as a computer chip, or any other object that can be viewed with an optical system such as a microscope, endoscope, telescope or camera. In some embodiments, the systems provide multiple images corresponding to various desired wavelength ranges within an original image of the object, as well as, if desired, directional pointer(s) that can provide both an identification of the precise location from which a spectrum is being obtained, as well as enhancing the ability to point the device.

Abstract translation: 提供来自物体的同时图像和光谱的光学系统，例如组织样本，诸如计算机芯片的工业对象或可以用诸如显微镜，内窥镜，望远镜或照相机的光学系统观察的任何其它物体 。 在一些实施例中，系统提供对应于对象的原始图像内的各种期望波长范围的多个图像，以及如果需要的方向指针，其可以提供频谱的精确位置的识别 获得，以及增强指向设备的能力。

公开(公告)号：US06885445B2

公开(公告)日：2005-04-26

申请号：US10211558

申请日：2002-08-05

Applicant: Robert Bennett ,  Andrew Mark Woolfrey ,  John Charles Clifford Day ,  Angus Bewick

Inventor： Robert Bennett ,  Andrew Mark Woolfrey ,  John Charles Clifford Day ,  Angus Bewick

IPC: G01J3/02 ,  G01J3/44 ,  G01Q20/02 ,  G01Q60/00 ,  H01J37/22 ,  H01J37/256 ,  G01J3/28 ,  H01J37/30

CPC classification number: H01J37/228 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/0216 ,  G01J3/0243 ,  G01J3/44 ,  H01J37/256 ,  H01J2237/2445 ,  H01J2237/2808

Abstract: An electron microscope 10 is adapted to enable spectroscopic analysis of a sample 16. A parabolic mirror 18 has a central aperture 20 through which the electron beam can pass. The mirror 18 focuses laser illumination from a transverse optical path 24 onto the sample, and collects Raman and/or other scattered light, passing it back to an optical system 30. The mirror 18 is retractable (within the vacuum of the electron microscope) by a sliding arm assembly 22.

Abstract translation: 电子显微镜10适于使得能够对样品16进行光谱分析。 抛物面反射镜18具有中心孔20，电子束可以穿过中心孔20。 反射镜18将来自横向光路24的激光照明聚焦到样品上，并收集拉曼和/或其他散射光，将其返回到光学系统30。 镜子18可以通过滑动臂组件22缩回（在电子显微镜的真空中）。

公开(公告)号：US20050043597A1

公开(公告)日：2005-02-24

申请号：US10723042

申请日：2003-11-26

Applicant: Jinchun Xie

Inventor： Jinchun Xie

IPC: A61B5/00 ,  C12Q20060101 ,  G01N21/65

CPC classification number: A61B5/6826 ,  A61B5/0066 ,  A61B5/14532 ,  A61B5/14546 ,  A61B5/1455 ,  A61B5/6838 ,  G01J3/0243 ,  G01N21/65

Abstract: Method and systems are provided for in vivo, non-invasive detection of blood analytes. A portion of the sterile matrix located beneath a nail is illuminated by passing radiation from an optical source through the nail into the sterile matrix. Scattered, refracted, or reflected radiation emitted within the sampled volume is collected and analyzed to identify and quantify one or more selected analytes.

Abstract translation: 提供了用于体内，非侵入性检测血液分析物的方法和系统。 位于指甲下方的无菌基质的一部分通过从光源通过指甲将辐射通过无菌基质来照射。 收集和分析在采样体积内发射的散射，折射或反射的辐射，以鉴定和量化一种或多种选择的分析物。

公开(公告)号：US20040057049A1

公开(公告)日：2004-03-25

申请号：US10668025

申请日：2003-09-19

Applicant: Applied Photonics Worldwide, Inc.

Inventor： Reinhard Bruch ,  Uwe Fritzsch ,  Thomas Gessner ,  Thomas Otto ,  Volker Stock

IPC: G01J003/28

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0243 ,  G01J3/0256 ,  G01J3/0294 ,  G01J3/04 ,  G01J3/18 ,  G01J2003/045

Abstract: The present invention relates to different types of micromirror spectrometers using MEMS (Micro Electro Mechanical Systems) for various applications in the UV, VIS, NIR and MIR wavelength regions. The invention enables a wavelength selection using micro scanning mirror and integrated grating on a much smaller scale than previously encountered conventional diffraction grating monochromators. Especially small designs are obtained via simultaneous usage of collimation optics for both spatial filters, by using entrance and exit slit apertures, which are located very close together. Until now, the spatial filters themselves are not part of the miniaturization. The utilization of the precision from this technology allows for reproducible slits with defined geometries and surface roughness and accurate spatial classification towards the rotation axis of the diffraction grating. Therefore the assembly and adjustment effort of the monochromator is reduced. Due to the option of additional slit apertures, several independent monochromator channels with crossed beam paths can be created; whereas all remaining optical elements (diffraction grating and collimator optic) are utilized together. Such additional channels can serve, for example, as reference measurements of a radiation source, or enable the direct optical control of the grating torsion angle as a monitoring channel. The goal of the invention is to define a simple design and arrangement for monochromators based upon micromechanical elements, which avoids all disadvantages described above.

Abstract translation: 本发明涉及使用MEMS（微机电系统）的不同类型的微镜光谱仪，用于UV，VIS，NIR和MIR波长区域中的各种应用。 本发明使得能够以比先前遇到的常规衍射光栅单色仪小得多的尺寸使用微扫描镜和集成光栅进行波长选择。 通过使用位于非常靠近的入口和出口狭缝孔，通过同时使用用于两个空间滤光器的准直光学器件来获得特别小的设计。 到目前为止，空间滤波器本身不是小型化的一部分。 利用这种技术的精度，允许具有确定的几何形状和表面粗糙度的可重复切割以及对于衍射光栅的旋转轴的准确的空间分类。 因此，单色仪的组装和调整工作减少了。 由于可选择附加的狭缝孔，可以产生具有交叉光束路径的几个独立的单色仪通道; 而所有剩余的光学元件（衍射光栅和准直器光学元件）被一起使用。 这样的附加通道可以例如用作辐射源的参考测量，或者可以将光栅扭转角的直接光学控制作为监视通道。 本发明的目标是基于微机械元件来定义用于单色仪的简单设计和布置，这避免了上述的所有缺点。

公开(公告)号：US06667805B2

公开(公告)日：2003-12-23

申请号：US09932548

申请日：2001-08-17

Applicant: Adam E. Norton ,  Kenneth C. Johnson ,  Fred E. Stanke

Inventor： Adam E. Norton ,  Kenneth C. Johnson ,  Fred E. Stanke

IPC: G01J328

CPC classification number: G01N21/31 ,  G01J3/02 ,  G01J3/0224 ,  G01J3/0243 ,  G01J3/28 ,  G01N21/956 ,  G02B5/3083 ,  G02B27/28

Abstract: A small-spot imaging, spectrometry instrument for measuring properties of a sample has a polarization-scrambling element, such as a Lyot depolarizer, incorporated between the polarization-introducing components of the system, such as the beamsplitter, and the microscope objective of the system. The Lyot depolarizer varies polarization with wavelength. Sinusoidal perturbation in the resulting measured spectrum can be removed by data processing techniques or, if the depolarizer is thick or highly birefringent, may be narrower than the wavelength resolution of the instrument.

公开(公告)号：US06534768B1

公开(公告)日：2003-03-18

申请号：US09699702

申请日：2000-10-30

Applicant: Emil W. Ciurczak ,  Kevin C. Bynum

Inventor： Emil W. Ciurczak ,  Kevin C. Bynum

IPC: G01J528

CPC classification number: G01N21/35 ,  G01J1/0455 ,  G01J1/4228 ,  G01J3/0243 ,  G01J3/10 ,  G01J3/12 ,  G01J3/1256 ,  G01J3/2803 ,  G01J2003/123 ,  G01J2003/1243 ,  G01J2003/1828 ,  G01J2003/2866 ,  G01N21/359 ,  G01N21/59

Abstract: A hemispherical detector comprising a plurality of photodetectors arranged in a substantially contiguous array, the array being substantially in the shape of a half-sphere, the half-sphere defining a closed end and an open end, the open end defining a substantially circular face. Also provided is a method for constructing a hemispherical detector comprising the steps of making a press mold of the desired shape of the hemispherical detector, pouring a material into the press mold to form a cast, finishing the cast to remove any defects, coating the cast with a coating material, and attaching a plurality of photodetectors to the cast.

Abstract translation: 一种半球形检测器，包括以基本上邻接的阵列布置的多个光电检测器，所述阵列基本上为半球形，所述半球限定封闭端和开口端，所述开口端限定基本圆形的面。 还提供了一种用于构造半球形检测器的方法，包括以下步骤：制造半球形检测器所需形状的压模，将材料注入压模中以形成铸件，精加工铸件以除去任何缺陷，涂覆铸件 涂覆材料，并将多个光电检测器附接到铸件上。