Microparticle analysis device and microparticle analysis method
    112.
    发明授权
    Microparticle analysis device and microparticle analysis method 有权
    微粒分析装置及微粒分析方法

    公开(公告)号:US08350232B2

    公开(公告)日:2013-01-08

    申请号:US13017554

    申请日:2011-01-31

    Abstract: Disclosed herein is a microparticle analysis device including: a light source configured to irradiate a microparticle with light; an acousto-optic modulator configured to diffract fluorescence generated from the microparticle due to the light irradiation; a slit configured to allow transmission of only diffracted light in a diffraction center wavelength region among diffracted light beams from the acousto-optic modulator; and a detector configured to detect the diffracted light in the diffraction center wavelength region transmitted through the slit.

    Abstract translation: 本发明公开了一种微粒分析装置,其特征在于,包括:被配置为用光照射微粒的光源; 配置为衍射由于光照射而从微粒产生的荧光的声光调制器; 狭缝,被配置为允许在来自声光调制器的衍射光束中的衍射中心波长区域中仅衍射衍射光; 以及检测器,被配置为检测通过狭缝透射的衍射中心波长区域中的衍射光。

    Coherency Reduction for Bandwidth Measurement
    113.
    发明申请
    Coherency Reduction for Bandwidth Measurement 审中-公开
    一致性降低带宽测量

    公开(公告)号:US20120162657A1

    公开(公告)日:2012-06-28

    申请号:US13411600

    申请日:2012-03-04

    Abstract: A method includes directing a portion of a laser beam output from a laser along a secondary beam path toward a detector, the secondary beam path being distinct from a main beam path of the laser beam; generating a bandwidth selective interference pattern of the laser beam on the detector; detecting, at the detector, a width of a fringe within the interference pattern to thereby measure measuring a bandwidth of the laser beam; and homogenizing the laser beam traveling along the secondary beam path prior to generation of the bandwidth selective interference pattern. The homogenizing includes diffusing the laser beam; and introducing a time dependent, position dependent, or both time and position dependent random modulation to the wavefront of the laser beam to reduce fluctuations in the detected fringe width and to reduce the influence of spatial coherence of the laser beam on the detected interference pattern.

    Abstract translation: 一种方法包括将从激光器输出的激光束的一部分沿着次级光束路径引向检测器,次级光束路径与激光束的主光束路径不同; 在检测器上产生激光束的带宽选择性干涉图案; 在检测器处检测干涉图案内的边缘的宽度,从而测量测量激光束的带宽; 并且在产生带宽选择干涉图案之前均匀化沿着次级光束路径行进的激光束。 均质化包括扩散激光束; 并且将与时间有关的位置依赖性或时间和位置相关随机调制引入到激光束的波前以减少检测到的条纹宽度的波动并减少激光束的空间相干性对检测到的干涉图案的影响。

    AOTF-BASED IMAGING SYSTEM AND METHOD FOR HYPERSPECTRAL AND MULTISPECTRAL IMAGING OF SPECIMENS INCLUDING MEDICAL TISSUE
    115.
    发明申请
    AOTF-BASED IMAGING SYSTEM AND METHOD FOR HYPERSPECTRAL AND MULTISPECTRAL IMAGING OF SPECIMENS INCLUDING MEDICAL TISSUE 有权
    基于AOTF的成像系统和方法,用于包括医疗组织的样本的高分辨和多重图像成像

    公开(公告)号:US20100246907A1

    公开(公告)日:2010-09-30

    申请号:US12675677

    申请日:2008-09-02

    Abstract: An imaging system includes a platform for placement of a sample or an animal to be imaged, and at least one excitation light source for irradiating the sample or animal to stimulate an emission at a plurality of different center wavelengths. An acousto-optic tunable filter (AOTF) is provided that includes a piezoelectric transducer crystal for emitting an acoustic wave having a ground electrode disposed on one side of the piezoelectric crystal. A patterned electrode layer is disposed on a side of the piezoelectric crystal opposite the ground electrode. The patterned electrode layer includes a continuous region proximate to its center and a discontinuous region, a pattern in the discontinuous region comprising a plurality of spaced apart features electrically connected to the continuous region, and an AO interaction crystal receiving the acoustic wave attached to the ground electrode or the patterned electrode layer.

    Abstract translation: 成像系统包括用于放置待成像的样品或动物的平台,以及用于照射样品或动物以刺激多个不同中心波长的发射的至少一个激发光源。 提供了一种声光可调滤波器(AOTF),其包括用于发射声波的压电换能器晶体,该声波具有设置在压电晶体一侧的接地电极。 图案化电极层设置在与接地电极相对的压电晶体的一侧。 图案化电极层包括靠近其中心的连续区域和不连续区域,不连续区域中的图案包括电连接到连续区域的多个间隔的特征,以及接收附着于地面的声波的AO相互作用晶体 电极或图案化电极层。

    NONINVASIVE DETECTION OF ELEMENTS AND/OR CHEMICALS IN BIOLOGICAL MATTER
    116.
    发明申请
    NONINVASIVE DETECTION OF ELEMENTS AND/OR CHEMICALS IN BIOLOGICAL MATTER 有权
    在生物学中非元素检测元素和/或化学物质

    公开(公告)号:US20100185067A1

    公开(公告)日:2010-07-22

    申请号:US12687469

    申请日:2010-01-14

    Applicant: Neelam Gupta

    Inventor: Neelam Gupta

    Abstract: A method of detecting oxygen and/or chemical content in a subject, comprising generating at least one spectral image of the subject; generating at least one spectral image of a reference object; comparing spectrum from the subject image to the reference image to thereby reveal the relative oxygen content of the subject. A system for determining the level of oxygenation of the blood of a subject body part comprising: a hyperspectral image generator for generating a plurality of spectral images; an image capture device for capturing the spectral images; a processor for generating hyperspectral image cubes such that the spectrum of the body part is extracted and normalized using the spectrum from the reference object to cancel out the spectral response of the light source and the imager; said processor comparing spectral from a subject image to reference images to thereby reveal the relative oxygen content of the subject.

    Abstract translation: 一种检测受试者中氧和/或化学含量的方法,包括产生所述受试者的至少一个光谱图像; 生成参考对象的至少一个光谱图像; 将来自对象图像的光谱与参考图像进行比较,从而显示对象的相对氧含量。 一种用于确定被摄体体部分的血液氧合水平的系统,包括:用于产生多个光谱图像的高光谱图像发生器; 用于捕获光谱图像的图像捕获装置; 用于产生高光谱图像立方体的处理器,使得使用来自参考对象的光谱提取和归一化身体部分的光谱,以抵消光源和成像器的光谱响应; 所述处理器将来自对象图像的光谱与参考图像进行比较,从而显示对象的相对氧含量。

    Hyperspectral scene projection/generation systems and methods
    117.
    发明授权
    Hyperspectral scene projection/generation systems and methods 有权
    高光谱场景投影/生成系统和方法

    公开(公告)号:US07733484B1

    公开(公告)日:2010-06-08

    申请号:US11239460

    申请日:2005-09-26

    CPC classification number: G01J3/1256 G01J3/0208 G01J3/10 G01J3/2823

    Abstract: Embodiments of hyperspectral scene projection/generation systems and methods are disclosed. One method embodiment, among others, comprises dispersing a beam of light at one of a plurality of selectable wavelengths, the beam of light corresponding to a scene, and displaying a spectral image of the scene corresponding to the dispersed beam of light at one of the plurality of selectable wavelengths.

    Abstract translation: 公开了高光谱场景投影/生成系统和方法的实施例。 一个方法实施例,其中包括将光束分散在多个可选择波长中的一个,对应于场景的光束,以及与分散的光束对应的场景的光谱图像显示在 多个可选择的波长。

    Optical spectrum analyzer
    119.
    发明授权
    Optical spectrum analyzer 有权
    光谱分析仪

    公开(公告)号:US07609383B2

    公开(公告)日:2009-10-27

    申请号:US12165721

    申请日:2008-07-01

    CPC classification number: G01J3/1256 G01J3/02 G01J3/0256 G01J9/0246 G01J9/04

    Abstract: An optical spectrum analyzer detects a light output that is dependent on the frequency of light in a wavelength range of light to be measured. The optical spectrum analyzer includes a waveguide acousto-optic tunable filter including a piezoelectric substrate, optical waveguides, and an IDT, a light source for providing, to the waveguide acousto-optic tunable filter, reference light having a particular wavelength outside the wavelength range, a driving circuit for providing, to the waveguide acousto-optic tunable filter, a high frequency signal for exciting an IDT, and an arithmetic device that, on the basis of the wavelength of selected light when reference light is incident, and an exciting frequency, corrects the wavelength of the selected light, which is obtained from the light to be measured.

    Abstract translation: 光谱分析仪检测取决于待测光的波长范围内的光的频率的光输出。 光谱分析仪包括波导声光可调谐滤波器,其包括压电基片,光波导和IDT,用于向波导声光可调谐滤波器提供在波长范围外具有特定波长的参考光的光源, 用于向波导声光可调滤波器提供用于激励IDT的高频信号的驱动电路,以及基于参考光入射时所选择的光的波长和激励频率的运算器件, 校正从被测光获得的所选择的光的波长。

    Wide concentration range gas detection
    120.
    发明授权
    Wide concentration range gas detection 有权
    浓度范围广泛的气体检测

    公开(公告)号:US07592595B1

    公开(公告)日:2009-09-22

    申请号:US11545004

    申请日:2006-10-06

    Abstract: A method and apparatus in which a first absorption measurement is made over a first frequency interval or set of frequency intervals including one or more absorptions from a spectral band of interest. The first absorption measurement is ideally selected to be near the frequency of a peak in the absorption spectrum, providing high sensitivity at low gas concentrations. A second absorption measurement is made over a second frequency interval. The second absorption measurement is made to include a contribution from the broadening of the absorption spectrum at higher concentrations. The second absorption measurement provides sensitivity at higher concentrations. The two absorption measurements are then combined to deduce the target sample concentration as the absorption line spectrum changes shape with concentration.

    Abstract translation: 一种方法和装置,其中在包括来自感兴趣的光谱带的一个或多个吸收的第一频率间隔或频率间隔的集合上进行第一吸收测量。 理想地,第一吸收测量被选择为接近吸收光谱峰值的频率,在低气体浓度下提供高灵敏度。 在第二频率间隔上进行第二吸收测量。 进行第二吸收测量包括在较高浓度下扩大吸收光谱的贡献。 第二次吸收测量在较高浓度下提供灵敏度。 然后将两个吸收测量结合起来,以随着吸收谱线的浓度变化而推导出目标样品浓度。

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