公开(公告)号：US08525114B2

公开(公告)日：2013-09-03

申请号：US11985275

申请日：2007-11-13

Applicant: John F. Schabron

Inventor： John F. Schabron

IPC: G01J3/427

CPC classification number: G01J3/427 ,  G01N21/3504 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/359 ,  G01N2021/399

Abstract: The present invention may include methods and apparatus for the detection of explosives using near infrared or infrared spectroscopy to detect nitro or even carbonyl groups. Embodiments may include, at least one radiation emitter may emit at least one wavelength towards a target. At least one reflected wavelength may be generated after the wavelength collides with the target. A reflected wavelength may then be detected by at least one detector and analyzed with an analyzer.

Abstract translation: 本发明可以包括使用近红外或红外光谱检测炸药以检测硝基或甚至羰基的方法和装置。 实施例可以包括，至少一个辐射发射器可朝向目标发射至少一个波长。 在波长与目标物体碰撞之后，可能会产生至少一个反射波长。 然后可以由至少一个检测器检测反射波长，并用分析仪进行分析。

公开(公告)号：US08137992B2

公开(公告)日：2012-03-20

申请号：US12931859

申请日：2011-02-11

Applicant: Anthony H. Cincotta

Inventor： Anthony H. Cincotta

IPC: G01N33/53 ,  C12Q1/00 ,  A01N61/00 ,  A01N43/58 ,  A01N43/60 ,  A61K31/00 ,  A61K31/50 ,  A61K31/495 ,  G01J3/42 ,  G01J3/427 ,  G01N13/00 ,  G01N30/84

CPC classification number: A61K31/498 ,  G01N33/6896 ,  Y10S436/815 ,  Y10T436/145555 ,  Y10T436/173845

Abstract: The present invention is directed to a method of identifying patients to be treated by dopamine agonist therapy comprising the step of analyzing a plasma or urine sample from said patient for concentrations of norepinephrine (NE), norepinephrine metabolites (NE metabolites), dopamine, dopamine metabolites, serotonin, serotonin metabolites, or fasting triglycerides, wherein one or more of: (a) NE metabolites, (b) NE/NE metabolites:dopamine/dopamine metabolites, (c) NE and serotonin, (d) NE/NE metabolites and serotonin, (e) NE and serotonin metabolites, (f) NE/NE metabolites and serotonin metabolites, or (g) NE is/are greater than about 30% over normal level; or dopamine/dopamine metabolites are less than about 30% below normal; or fasting triglycerides are greater than about 150 mg/dl and/or said patient has blood pressure of greater than about 135/85 mm Hg. The present invention is also directed to treating identified patients with dopamine agonist therapy.

Abstract translation: 本发明涉及一种通过多巴胺激动剂治疗来鉴定待治疗患者的方法，包括以下步骤：从去甲肾上腺素（NE），去甲肾上腺素代谢物（NE代谢物），多巴胺，多巴胺代谢物的浓度分析来自所述患者的血浆或尿样品 （a）NE代谢产物，（b）NE / NE代谢产物：多巴胺/多巴胺代谢产物，（c）NE和5-羟色胺，（d）NE / NE代谢产物和 5-羟色胺，（e）NE和5-羟色胺代谢物，（f）NE / NE代谢物和5-羟色胺代谢物，或（g）NE比正常水平高大约30％ 或多巴胺/多巴胺代谢物低于正常值的约30％ 或空腹甘油三酸酯大于约150mg / dl，和/或所述患者具有大于约135/85mm Hg的血压。 本发明还涉及治疗多巴胺激动剂治疗的鉴定患者。

公开(公告)号：US20120011918A1

公开(公告)日：2012-01-19

申请号：US12838204

申请日：2010-07-16

Applicant: Fernando Bacal ,  Fabiana Goulart Marcondes Braga ,  Ivano Gebhardt Rolf Gutz ,  Guilherme Lopes Batista

Inventor： Fernando Bacal ,  Fabiana Goulart Marcondes Braga ,  Ivano Gebhardt Rolf Gutz ,  Guilherme Lopes Batista

IPC: G01J3/427 ,  G01J3/00 ,  B01D59/44 ,  C07C49/08 ,  G01N30/02

CPC classification number: A61B5/097 ,  A61B5/082 ,  A61B5/091 ,  A61B5/411 ,  A61B5/413

Abstract: The invention application presents a fast, efficient, reproductive alternative of a non-invasive method for diagnosing the severity of heart failure based on a specific biomarker. An additional object of the present invention is a collector device for the biomarker from exhaled breath that is portable, simple, low cost and does not need to run on electric power. This invention advantageously permits the replacement of invasive diagnosis methods, favoring the patient's comfort in addition to the agility and speed of medical attention at hospitals, and may become a standard method for all suspected cases of circulatory disease and heart failure and, more specifically, decompensated heart failure.

Abstract translation: 本发明应用提供了一种用于基于特定生物标志物诊断心力衰竭严重程度的非侵入性方法的快速，有效，生殖的替代方案。 本发明的另一个目的是一种用于呼出呼吸的生物标志物的收集器装置，其便携式，简单，低成本并且不需要在电力上运行。 本发明有利地允许替代侵入性诊断方法，除了医院的敏捷性和医疗护理速度之外，有利于患者的舒适度，并且可以成为所有疑似循环系统疾病和心力衰竭病例的标准方法，更具体而言，代偿失调 心脏衰竭。

公开(公告)号：US07903260B1

公开(公告)日：2011-03-08

申请号：US12699816

申请日：2010-02-03

Applicant: Gary R. Janik

Inventor： Gary R. Janik

IPC: G01B11/30 ,  G01B11/14 ,  G01J3/44 ,  G01J3/427 ,  G01J3/28

CPC classification number: G01B11/0616 ,  G01N21/65 ,  G01N2021/653

Abstract: A system for characterizing material properties in miniature semiconductor structures performs a scatterometry analysis on inelastically scattered light. The system can include a narrowband probe beam generator and a detector. A single wavelength probe beam from the narrowband probe beam generator produces scattered light from a measurement pattern on a test sample. The scattered light is measured by the detector, and the measurement data (e.g., Raman spectrum) is used in a scatterometry analysis to determine material properties for the measurement pattern. The detector can measure either incoherent inelastically scattered light (e.g., using a spectrometer) or coherent inelastically scattered light (e.g., using an array detector). If the measurement pattern dimensions are substantially similar to actual device dimensions, the material property distributions determined for the measurement pattern can be applied to the actual devices on the test sample.

Abstract translation: 用于表征微型半导体结构中的材料性质的系统对非弹性散射光进行散射分析。 该系统可以包括窄带探测光束发生器和检测器。 来自窄带探测光束发生器的单个波长探测光束从测试样品上的测量图形产生散射光。 通过检测器测量散射光，并且在散射分析中使用测量数据（例如，拉曼光谱）来确定测量图案的材料特性。 检测器可以测量非相干非弹性散射光（例如，使用光谱仪）或相干非弹性散射光（例如，使用阵列检测器）。 如果测量图形尺寸基本上类似于实际的装置尺寸，则可以将测量图案确定的材料特性分布应用于测试样品上的实际装置。

公开(公告)号：US20100290031A1

公开(公告)日：2010-11-18

申请号：US12297014

申请日：2007-04-13

Applicant: Wilhelm Luedeker

Inventor： Wilhelm Luedeker

IPC: G01J3/36 ,  G01N21/31 ,  G01J3/427

CPC classification number: G01N21/31 ,  G01J3/32 ,  G01J3/36 ,  G01J3/42 ,  G01J2003/1213 ,  G01N21/314

Abstract: The invention relates to a method and a device for determining a predefined spectral range, particularly the spectral range around the red edge. In said method, the analysis of the spectral range is carried out by means of two overlapping spectral value functions. The invention also relates to a method and a system for characterizing existent vegetation.

Abstract translation: 本发明涉及一种用于确定预定光谱范围的方法和装置，特别是围绕红色边缘的光谱范围。 在所述方法中，通过两个重叠的光谱值函数来进行光谱范围的分析。 本发明还涉及用于表征现有植被的方法和系统。

公开(公告)号：US07692784B2

公开(公告)日：2010-04-06

申请号：US10952374

申请日：2004-09-27

Applicant: Nicholas B. MacKinnon ,  Ulrich Stange

Inventor： Nicholas B. MacKinnon ,  Ulrich Stange

IPC: G01J3/00 ,  G01J3/42 ,  G01J3/427 ,  G01J3/28

CPC classification number: G01J1/32 ,  G01J3/027 ,  G01J3/0286 ,  G01J3/10 ,  G01J3/12 ,  G01J3/26 ,  G01J3/2803 ,  G01J3/42 ,  G01J3/4406 ,  G01J2003/1282 ,  G01J2003/1286 ,  G01N21/31 ,  G01N21/39 ,  G01N2021/3155

Abstract: The apparatus and methods herein provide light sources and spectral measurement systems that can improve the quality of images and the ability of users to distinguish desired features when making spectroscopy measurements by providing methods and apparatus that can improve the dynamic range of data from spectral measurement systems.

Abstract translation: 本文提供的装置和方法提供光源和光谱测量系统，其可以通过提供可以改进来自光谱测量系统的数据的动态范围的方法和装置来提高图像的质量和用户区分所需特征的能力。

公开(公告)号：US07483133B2

公开(公告)日：2009-01-27

申请号：US11078572

申请日：2005-03-11

Applicant: Noah Bareket ,  Haiming Wang

Inventor： Noah Bareket ,  Haiming Wang

IPC: G01J3/28 ,  G01J3/42 ,  G01J3/427 ,  G01B11/14 ,  G01B11/04 ,  G01B11/08

CPC classification number: G01B11/0641 ,  G01N21/211 ,  G01N21/956

Abstract: Techniques for optimizing the sensitivity of spectroscopic measurement techniques with respect to certain profile variables by selecting desired measurement angles since the measurement sensitivity to each variable depends, at least in part, on the measurement angles of an incident beam. The selected desired set of measurement angles includes both an azimuth angle and a polar angle. Optimizing the sensitivity of spectroscopic measurement techniques can also reduce or eliminates measurement correlation among variable to be measured.

Abstract translation: 由于对每个变量的测量灵敏度，因此通过选择所需的测量角度来优化光谱测量技术对某些分布变量的灵敏度的技术，至少部分取决于入射光束的测量角度。 所选择的所需的测量角度集合包括方位角和极角。 优化光谱测量技术的灵敏度也可以减少或消除待测量的变量之间的测量相关性。

公开(公告)号：US20080123094A1

公开(公告)日：2008-05-29

申请号：US11792097

申请日：2005-12-01

Applicant: Henrik Vilstrup Juhl

Inventor： Henrik Vilstrup Juhl

IPC: G01J3/427

CPC classification number: G01N21/0303 ,  G01N21/31 ,  G01N2021/036 ,  G01N2201/066 ,  G01N2201/0662 ,  G01N2201/1293

Abstract: A spectrophotometer (2) comprising a source of radiation (6), preferably optical radiation, disposed to emit radiation at a plurality of wavelengths towards a sample in a sample holder (4) and a detection arrangement 8 for detecting the radiation after its interaction with the sample. The sample holder (4) is adapted to present a plurality of different path lengths for the emitted radiation through the sample. An arithmetic unit (10;10b) is operably connected to receive an intensity dependent output from the detection arrangement (8) and is adapted to store an intensity value of the detected emitted radiation indexed to its wavelength at two or more path lengths of the plurality of different path lengths and to calculate a value dependent on the ratio of the indexed intensity values at each of two path lengths by which an indication of the presence of a substance of interest withiA spectrophotometer (2) comprise a source of radiation (6), preferably optical radiation, disposed to emit radiation at a plurality of wavelengths towards a sample in a sample holder (4) and a detection arrangement 8 for detecting the radiation after its interaction with the sample. The sample holder (4) is adapted to present a plurality of different path lengths for the emitted radiation through the sample. An arithmetic unit (10;10b) is operably connected to receive an intensity dependent output from the detection arrangement (8) and is adapted to store an intensity value of the detected emitted radiation indexed to its wavelength at two or more path lengths of the plurality of different path lengths and to calculate a value dependent on the ratio of the indexed intensity values at each of two path lengths by which an indication of the presence of a substance of interest within the retained sample can be obtained.

Abstract translation: 一种分光光度计（2），包括辐射源（6），优选光辐射，被设置成朝向样品保持器（4）中的样品发射多个波长的辐射;以及检测装置8，用于在与 例子。 样品保持器（4）适于对通过样品的发射辐射呈现多个不同的路径长度。 算术单元（10; 10b）可操作地连接以接收来自检测装置（8）的强度相关输出，并且适于将检测到的发射的辐射的强度值存储在其波长的两个或更多个路径长度上 多个不同的路径长度并且计算取决于两个路径长度中的每一个处的索引强度值的比率的值，通过该值，用分光光度计（2）存在感兴趣的物质的指示包括辐射源（6） 优选地，光辐射被设置为发射多个波长的辐射朝向样本保持器（4）中的样本;以及检测装置8，用于在与样本相互作用之后检测辐射。 样品保持器（4）适于对通过样品的发射辐射呈现多个不同的路径长度。 算术单元（10; 10b）可操作地连接以接收来自检测装置（8）的强度相关输出，并且适于将检测到的发射的辐射的强度值存储在其波长的两个或更多个路径长度上 多个不同的路径长度，并且计算取决于两个路径长度中的每一个处的索引强度值的比率的值，由此可以获得在保留的样本内存在感兴趣的物质的指示。

公开(公告)号：US20080094625A1

公开(公告)日：2008-04-24

申请号：US11902347

申请日：2007-09-20

Applicant: Seetharama Deevi ,  Edward Carmines

Inventor： Seetharama Deevi ,  Edward Carmines

IPC: G01J3/42 ,  G01J3/427

CPC classification number: G01N21/3563 ,  G01N21/359 ,  G01N2021/8466 ,  G01N2201/0221

Abstract: A system for detecting nitrates in a tobacco sample having a light source, and a detection device. The light source provides a beam of light incident to a tobacco sample, which is reflected from the tobacco sample to the detection device. A computing device computes the amount of nitrates within the tobacco sample based on data received from the detection device to correlate the amount of tobacco-specific nitrosamines within the tobacco sample.

Abstract translation: 一种用于检测具有光源的烟草样品中的硝酸盐的系统和检测装置。 光源提供入射到烟草样品的光束，烟丝样品从烟草样品反射到检测装置。 计算设备基于从检测装置接收的数据来计算烟草样品中的硝酸盐的量，以使烟草样品中烟草特异性亚硝胺的量相关。

公开(公告)号：US07202949B2

公开(公告)日：2007-04-10

申请号：US10954388

申请日：2004-09-30

Applicant: Erin M. Weeks ,  Kenneth Brecher

Inventor： Erin M. Weeks ,  Kenneth Brecher

IPC: G01J3/28 ,  G01J3/42 ,  G01J3/427

CPC classification number: G01J3/04 ,  G01J3/0272 ,  G01J3/0291 ,  G01J3/1838 ,  G01J3/30

Abstract: A direct-view handheld binocular spectrometer for use in a variety of educational settings. The device comprises a holographic transmission diffraction grating and a uniquely curved quantitative wavelength scale for viewing visible-wavelength spectra with both eyes simultaneously. A variable width entrance slit, adjustable illumination for the wavelength scale, and attachable corrective lenses enhance the ease of use and efficiency as compared to traditional monocular spectrometers.

Abstract translation: 一种用于各种教育环境的直视手持式双目光谱仪。 该装置包括全息透射衍射光栅和唯一弯曲的定量波长标度，用于同时用双眼观察可见光波长光谱。 与传统的单目光谱仪相比，可变宽度入口狭缝，可调节的波长标度照明和可连接的矫正镜片增强了使用和效率的便利性。