Non-Invasive System and Method for Measuring an Analyte in the Body
    121.
    发明申请
    Non-Invasive System and Method for Measuring an Analyte in the Body 有权
    非侵入性体系和体内分析物测定方法

    公开(公告)号:US20090062632A1

    公开(公告)日:2009-03-05

    申请号:US11918537

    申请日:2006-04-13

    Inventor: Mihailo V. Rebec

    Abstract: A system for determining an analyte concentration in a fluid sample (e.g., glucose) comprises a light source, a detector, and a central processing unit. The detector is adapted to receive spectral information corresponding to light returned from the fluid sample being analyzed and to convert the received spectral information into an electrical signal indicative of the received spectral information. The central processing unit is adapted to compare the electrical signal to an algorithm built upon correlation with the analyte in body fluid. The algorithm is adapted to convert the received spectral information into the analyte concentration in body fluid. Spectral information is delivered from the central processing unit to the light source and used to vary the intensity and timing of the light to improve the accuracy of conversion into analyte concentration.

    Abstract translation: 用于确定流体样品(例如葡萄糖)中的分析物浓度的系统包括光源,检测器和中央处理单元。 检测器适于接收对应于正在分析的流体样品返回的光的光谱信息,并将接收到的光谱信息转换为指示所接收的光谱信息的电信号。 中央处理单元适于将电信号与建立在体液中分析物相关的算法进行比较。 该算法适用于将接收到的光谱信息转换成体液中的分析物浓度。 光谱信息从中央处理单元传送到光源,并用于改变光的强度和时间,以提高转换成分析物浓度的准确度。

    Device for controlling light radiation
    122.
    发明申请
    Device for controlling light radiation 审中-公开
    用于控制光辐射的装置

    公开(公告)号:US20080088907A1

    公开(公告)日:2008-04-17

    申请号:US11998418

    申请日:2007-11-30

    Abstract: Device for controlling light radiation, which is excited in a specimen and/or which is backscattered and/or reflected and which contains one or more wavelengths, at a plurality of light outlets, wherein a separation of the light radiation into differently polarized components is carried out; and the components of the excitation radiation and/or detection radiation are affected in their polarization by means of a preferably birefringent, preferably acousto-optic or electro-optic medium, which changes the ordinary and extraordinary refractive index.

    Abstract translation: 用于控制在多个光出口处在样本中激发并且/或背散射和/或反射并且包含一个或多个波长的光辐射的装置,其中将光辐射分离成不同偏振的分量 出来 并且激发辐射和/或检测辐射的分量通过改变普通和非凡折射率的优选双折射,优选声光或电光介质在它们的极化中受到影响。

    Multi-channel dual phase lock-in optical spectrometer
    123.
    发明授权
    Multi-channel dual phase lock-in optical spectrometer 失效
    多通道双相锁相光谱仪

    公开(公告)号:US07336357B2

    公开(公告)日:2008-02-26

    申请号:US11202211

    申请日:2005-08-12

    Applicant: Jeremy Levy

    Inventor: Jeremy Levy

    Abstract: The development of a multiple-channel dual phase lock-in optical spectrometer (LIOS) is presented, which enables parallel phase-sensitive detection at the output of an optical spectrometer. The light intensity from a spectrally broad source is modulated at the reference frequency, and focused into a high-resolution imaging spectrometer. The height at which the light enters the spectrometer is controlled by an acousto-optic deflector, and the height information is preserved at the output focal plane. A two-dimensional InGaAs focal plane array collects light that has been dispersed in wavelength along the horizontal direction, and in time along the vertical direction. The data is demodulated using a high performance computer-based digital signal processor. This parallel approach greatly enhances (by more than 100×) the speed at which spectrally resolved lock-in data can be acquired.

    Abstract translation: 提出了一种多通道双相锁相光谱仪(LIOS)的开发,可在光谱仪的输出端进行并行相敏检测。 来自光谱宽源的光强度以参考频率调制,并且聚焦成高分辨率成像光谱仪。 光进入光谱仪的高度由声光偏转器控制,高度信息保留在输出焦平面。 二维InGaAs焦平面阵列沿着水平方向并沿着垂直方向在时间上收集沿波长分散的光。 使用基于高性能计算机的数字信号处理器对数据进行解调。 这种并行方法极大地提高了可以获取光谱解析的锁定数据的速度(超过100倍)。

    Imaging apparatus and light source estimating device for the imaging apparatus
    125.
    发明申请
    Imaging apparatus and light source estimating device for the imaging apparatus 有权
    用于成像装置的成像装置和光源估计装置

    公开(公告)号:US20080001063A1

    公开(公告)日:2008-01-03

    申请号:US11798069

    申请日:2007-05-10

    CPC classification number: G01J3/44 G01J3/1256 G01J3/2823 G01J2003/1213

    Abstract: A light source estimating device includes: a distribution holding section holding a spectral energy distribution of a specific light source as a specular reflection component; a set generating section generating a set determined by the specular reflection component and pixel data of the input image in a predetermined space, with respect to each pixel data of the input image; a detecting section detecting, with respect to each pixel data of the input image, another pixel data neighboring the pixel data and included in the set; and a determining section determining whether or not the specific light source corresponds to the light source used during capture, by setting a likelihood that the specific light source corresponds to the light source used during capture high if the other pixel data exists, and setting a likelihood that the specific light source corresponds to the light source used during capture low if the other pixel data does not exist.

    Abstract translation: 光源估计装置包括:保持特定光源的光谱能量分布作为镜面反射分量的分布保持部; 相对于输入图像的每个像素数据产生由预测空间中的输入图像的镜面反射分量和像素数据确定的集合的集合生成部分; 检测部,相对于所述输入图像的每个像素数据检测与所述集合中包含的像素数据相邻的另一像素数据; 以及确定部分,通过将特定光源对应于捕获期间使用的光源的可能性设置为高,如果存在其他像素数据,则确定特定光源是否对应于捕获期间使用的光源,并且设置似然 如果其他像素数据不存在,则特定光源对应于捕获期间使用的光源低。

    Optical spectrum analyzer
    126.
    发明申请
    Optical spectrum analyzer 审中-公开
    光谱分析仪

    公开(公告)号:US20070177141A1

    公开(公告)日:2007-08-02

    申请号:US11699463

    申请日:2007-01-30

    Abstract: An optical spectrum analyzer includes an optical section 130 for executing light dispersion into a spectrum and wavelength sweep for input measured light, converting the measured light into an electric signal, and outputting the electric signal, a control section 101 for controlling the wavelength sweep of the optical section and outputting a sampling clock of a period shifting from a cycle period of the measured light for each wavelength of the wavelength sweep, and a measurement section 140 for executing sequential sampling of the electric signal from the optical section for each sampling clock.

    Abstract translation: 光谱分析仪包括用于对输入测量光进行光谱分散和波长扫描的光学部分130,将测量的光转换成电信号并输出​​电信号;控制部分101,用于控制波长扫描 并且输出从波长扫描的每个波长的测量光的周期周期移位的周期的采样时钟,以及用于对每个采样时钟执行来自光学部分的电信号的顺序采样的测量部分140。

    Hyperspectral sensor using tunable filter
    127.
    发明申请
    Hyperspectral sensor using tunable filter 审中-公开
    高光谱传感器采用可调滤波器

    公开(公告)号:US20070045545A1

    公开(公告)日:2007-03-01

    申请号:US11215204

    申请日:2005-08-26

    Abstract: A target-seeking-and-tracking system featuring hyperspectral sensing performed by a tunable filter and an infrared focal plane array is programmable to collect and process several hyperspectral bands of infrared radiation emanating from a target scenery. The programming is done by tuning the filter from time to time to collect several hyperspectral bands containing image data corresponding to several objects of interest in the scenery. The image data is further processed in the target recognition unit to identify the objects and aid in the selection and tracking of a particular target object for the ultimate goal of accurate destruction of the object. The programmability of hyperspectral sensing provides a degree of countermeasures immunity by allowing several bands to be combined to achieve the best signal-to-clutter ratio.

    Abstract translation: 由可调滤波器和红外焦平面阵列执行的具有高光谱感测的寻靶跟踪系统是可编程的,用于收集和处理从目标风景发出的红外辐射的多个高光谱带。 编程是通过不时地调整滤波器来收集几个包含与风景中感兴趣的几个对象相对应的图像数据的高光谱带。 图像数据在目标识别单元中被进一步处理以识别对象,并帮助特定目标对象的选择和跟踪,以达到准确地破坏对象的最终目的。 高光谱传感器的可编程性通过允许多个频带组合以实现最佳的信噪比提供了一定程度的对策抗扰度。

    Portable acousto-optical spectrometers
    128.
    发明申请
    Portable acousto-optical spectrometers 有权
    便携式声光谱仪

    公开(公告)号:US20070041075A1

    公开(公告)日:2007-02-22

    申请号:US11208123

    申请日:2005-08-18

    Abstract: A portable acousto-optical (AO) spectrometer system comprised of at least one AO crystal cell device specially designed for cancellation of side-lobe noise at a desired tuned wavelength of operation. Each AO crystal cell device has a transducer attached and forms an AO tunable filter (AOTF) and forms part of a photo-head assembly. The system can include an optical fiber link between the AO spectrometer photo-head assembly and additional features such as an optical alignment coupling attachment that couple an excitation source such as a laser that operates in either pulse or continuous mode, a probing fiber that provides a hand-held member that can emit a source radiation and in turn observe radiation reflected from an observed sample. There are two embodiment of the AO crystal cell device. Either embodiment of the AO crystal cell design can be used in the system, providing a vibration-insensitive AO spectrometer instrument having high sensitivity, accuracy and resolution capabilities. The types of spectroscopic measurements that can be performed using the invention include fluorescence, Raman, absorption and emission.

    Abstract translation: 一种便携式声光(AO)光谱仪系统,包括至少一个专门设计用于消除所需调谐波长工作波长的旁瓣噪声的AO晶体元件。 每个AO晶体元件都安装有传感器,并形成一个AO可调谐滤波器(AOTF),并形成光头组件的一部分。 该系统可以包括在AO光谱仪光头组件和附加特征之间的光纤链路,例如耦合诸如以脉冲或连续模式操作的激光器的激发源的光学对准耦合附件,提供 可以发射源辐射的手持构件,然后观察从观察到的样品反射的辐射。 AO晶体元件的两个实施例。 可以在系统中使用AO晶体设计的任一实施例,提供具有高灵敏度,精确度和分辨率能力的不振动的AO光谱仪器。 可以使用本发明进行的光谱测量的类型包括荧光,拉曼,吸收和发射。

    System for obtaining images in bright field and crossed polarization modes and chemical images in Raman, luminescence and absorption modes
    129.
    发明申请
    System for obtaining images in bright field and crossed polarization modes and chemical images in Raman, luminescence and absorption modes 有权
    用于在拉曼,发光和吸收模式下在明场和交叉极化模式和化学图像中获得图像的系统

    公开(公告)号:US20060170907A1

    公开(公告)日:2006-08-03

    申请号:US11393395

    申请日:2006-03-30

    Applicant: David Tuschel

    Inventor: David Tuschel

    Abstract: An integrated system including one or more light sources, at least one processor, an optical lens, a two-dimensional tunable filter, one or more two-dimensional array of detection elements and instructions and a method using the integrated system. The system includes a plurality of modes: a Raman mode, an absorption mode, a luminescence mode, a crossed polarization mode, a crossed polarization absorption mode, bright field transmission or reflectance modes and a birefringence mode. The system includes instructions, executable by Sequential outputs from the two-dimensional array of detection elements is combined to generate a chemical image of the sample, wherein each of the sequential outputs from the first two-dimensional array of detection elements corresponds to spatially accurate wavelength-resolved images. The system is also used to detect dynamic changes in a sample over time by monitoring the sample using one or more of the modes.

    Abstract translation: 包括一个或多个光源的集成系统,至少一个处理器,光学透镜,二维可调滤波器,检测元件和指令的一个或多个二维阵列以及使用该集成系统的方法。 该系统包括多种模式:拉曼模式,吸收模式,发光模式,交叉偏振模式,交叉偏振吸收模式,亮场透射或反射模式和双折射模式。 该系统包括可由来自检测元件的二维阵列的顺序输出执行的指令,以组合以产生样本的化学图像,其中来自检测元件的第一二维阵列的每个顺序输出对应于空间上准确的波长 解决的图像。 该系统还用于通过使用一种或多种模式监测样品来随时间检测样品中的动态变化。

    Sensor and methods for measuring select components in sheetmaking systems
    130.
    发明申请
    Sensor and methods for measuring select components in sheetmaking systems 有权
    用于测量制片系统中选择组件的传感器和方法

    公开(公告)号:US20060132796A1

    公开(公告)日:2006-06-22

    申请号:US11018167

    申请日:2004-12-20

    Applicant: Frank Haran

    Inventor: Frank Haran

    Abstract: An efficient and versatile spectrometric sensor can be configured with an acousto-optic tunable filter. With this diverse spectral filter, the central wavelength and bandwidth of the filter can be quickly tuned to the desired wavelength. A sensor, for measuring at least selected component in a composition, can include: (a) a broadband light source, (b) an acousto-optic tunable filter (AOTF), (c) means for generating a beam of light from the light source and directing the beam of light at the AOTF wherein the AOTF is tuned to pass detection light having a desired wavelength range to detect the presence of the at least one component in the composition, (d) means for directing the detection light of known wavelength to the composition, (e) detection means for receiving light that emerges from the composition, and (f) a program structure that is coupled to the AOTF, the program structure capable of providing the AOTF with at least one desired wavelength range that is characteristic of the least one component in the composition. In addition, the device can be configured so that the AOTF is on the detection side of the sensor. The sensors can be used to measure the thickness of optically transparent films.

    Abstract translation: 一个高效和通用的光谱测量传感器可配置一个声光可调滤波器。 利用这种不同的光谱滤波器,可以将滤波器的中心波长和带宽快速调谐到所需的波长。 用于测量组合物中的至少所选组分的传感器可以包括:(a)宽带光源,(b)声光可调滤波器(AOTF),(c)用于产生来自所述光的光束的装置 源极和引导在AOTF处的光束,其中AOTF被调谐以通过具有期望波长范围的检测光,以检测组合物中至少一个成分的存在,(d)用于引导已知波长的检测光的装置 (e)用于接收从组合物出射的光的检测装置,以及(f)耦合到AOTF的程序结构,能够向AOTF提供至少一个期望的波长范围的程序结构,该期望波长范围是特征 的组合物中的至少一种组分。 另外,该装置可以被配置成使AOTF位于传感器的检测侧。 传感器可用于测量光学透明膜的厚度。

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