公开(公告)号：US20040076548A1

公开(公告)日：2004-04-22

申请号：US10682322

申请日：2003-10-09

Inventor： Jurgen Wulf

IPC: G01N021/64

CPC classification number: G01N21/643 ,  G01N21/6428 ,  G01N21/6452 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/6469 ,  G01N2201/065

Abstract: The present invention relates to a device for the detection of a fluorescent dye in a sample, comprising a radiation source means with the aid of which light for exciting the fluorescent dye to be detected can be transmitted into the sample applied to a carrier, and a detecting means for detecting fluorescent light which has been emitted by the fluorescent dye to be detected. The present invention is characterized by a hollow space having an internal high-reflectance surface, a first aperture directed towards the sample, and a second aperture located opposite the detecting means.

Abstract translation: 本发明涉及一种用于检测样品中的荧光染料的装置，其包括用于激发要检测的荧光染料的光的辐射源装置可以传输到施加到载体的样品中，并且 用于检测由待检测的荧光染料发射的荧光的检测装置。 本发明的特征在于具有内部高反射率表面，朝向样品的第一孔和与检测装置相对的第二孔的中空空间。

公开(公告)号：US06721048B2

公开(公告)日：2004-04-13

申请号：US09922845

申请日：2001-08-07

Applicant: Kazumi Yokota ,  Kaori Kinoshita

Inventor： Kazumi Yokota ,  Kaori Kinoshita

IPC: G01J342

CPC classification number: G01J3/36 ,  G01J1/04 ,  G01J3/0254 ,  G01N2201/065

Abstract: In a detector for spectrometry attached to an integrating sphere, a plurality of detection elements having different spectral sensitivity characteristics is arranged side by side in the same plane on a base, and a side cover is provided such that the detection elements receive light. Thus, the measurement light is directly irradiated to the respective detection elements. Accordingly, the detector for spectrometry has a fast response speed and is excellent in the sensitivity characteristics in a wide wavelength region in the near-infrared area.

Abstract translation: 在附着于积分球的光谱测定装置中，具有不同光谱灵敏度特性的多个检测元件并排设置在基座的同一平面上，并且设置侧盖，使得检测元件接收光。 因此，测量光直接照射到各个检测元件。 因此，用于光谱测定的检测器具有快速的响应速度，并且在近红外区域的宽波长区域中的灵敏度特性优异。

公开(公告)号：US20040000015A1

公开(公告)日：2004-01-01

申请号：US10345249

申请日：2003-01-16

Applicant: SEETHROUGH Ltd.

Inventor： Israel Grossinger ,  Avigdor Schertz ,  Michel Mercier ,  Eli Benny

IPC: A61K007/13

CPC classification number: A45D44/005 ,  A45D2019/0066 ,  A45D2044/007 ,  A61B5/103 ,  A61B5/417 ,  A61B5/448 ,  A61B5/6803 ,  G01J3/0251 ,  G01J3/46 ,  G01J3/463 ,  G01J3/50 ,  G01N21/251 ,  G01N21/84 ,  G01N2021/8444 ,  G01N2201/065

Abstract: A method to change the color of hair. The method includes measuring an initial reflectance spectrum of a sample of the hair and analyzing a contribution of a plurality of natural hair factors to the initial reflectance spectrum. The method also includes calculating a hair treatment based on another reflectance spectrum. A system to measure a reflectance spectrum of a sample includes an integrating sphere having a sampling port and an inner surface and a window disposed near to the sampling port. The window is configured for being placed in close contact with the sample. The system also includes a light source configured to project light onto the sample via the window and a light detector configured to analyze light reflected from the inner surface to produce the reflectance spectrum of the sample.

Abstract translation: 改变头发颜色的方法。 该方法包括测量毛发样品的初始反射光谱并分析多种天然毛发因子对初始反射光谱的贡献。 该方法还包括基于另一反射光谱计算毛发处理。 用于测量样品的反射光谱的系统包括具有采样端口和内表面的积分球和靠近采样端口设置的窗口。 窗口配置为与样品紧密接触。 该系统还包括被配置为经由窗口将光投射到样品上的光源和被配置为分析从内表面反射的光以产生样品的反射光谱的光检测器。

公开(公告)号：US06626052B1

公开(公告)日：2003-09-30

申请号：US09180079

申请日：1999-08-02

Applicant: Jonathan Martin ,  Joannie Chin

Inventor： Jonathan Martin ,  Joannie Chin

IPC: G01N1700

CPC classification number: G01N17/004 ,  G01N21/474 ,  G01N2201/065

Abstract: A method and apparatus for irradiating a specimen with a beam of radiation are provided. The method comprises the steps of providing an integrating sphere, a radiation source radiatively communicating with the sphere, and a specimen, the integrating sphere radiatively communicating with the specimen through an aperture in the sphere. The apparatus comprises a radiation source, an integrating sphere in radiative communication with the radiation source, and a specimen holder in radiative communication with the integrating sphere. The disclosed apparatus and method allow the irradiance of a beam of radiation impinging on the specimen to be maintained at a uniform level across the width of the beam to allow quantitative specimen evaluation.

Abstract translation: 提供了用辐射束照射样本的方法和装置。 该方法包括以下步骤：提供积分球，与球体辐射连通的辐射源以及通过球体中的孔与样本辐射连通的样本。 该装置包括辐射源，与辐射源辐射连通的积分球和与积分球辐射连通的样本保持器。 所公开的装置和方法允许辐射入射到试样上的辐射束在光束的宽度上保持在均匀的水平，以允许定量试样评价。

公开(公告)号：US06603555B1

公开(公告)日：2003-08-05

申请号：US09478828

申请日：2000-01-06

Applicant: Masaya Nanami ,  Toshiyuki Suzuki ,  Takeshi Tsukamoto

Inventor： Masaya Nanami ,  Toshiyuki Suzuki ,  Takeshi Tsukamoto

IPC: G01N2161

CPC classification number: G01N21/39 ,  G01N2201/065

Abstract: A gas detecting apparatus includes a gas cell, a laser source, a light diffuser and a photodetector. The gas cell has a gas inlet hole for letting the target gas come inside and a gas discharge hole for discharging the target gas, and retains a target gas to be detected. The laser source emits coherent light into the gas cell in order to detect a concentration of the target gas. The light diffuser is disposed in the optical path of the coherent light output from the laser source to diffuse the coherent light, thereby eliminating coherence of the coherent light. The photodetector receives light diffused by the light diffuser.

Abstract translation: 气体检测装置包括气体单元，激光源，光扩散器和光电检测器。 气室具有用于使目标气体进入的气体入口孔和用于排出目标气体的气体排出孔，并且保留待检测的目标气体。 激光源将相干光发射到气室中，以便检测目标气体的浓度。 光扩散器设置在从激光源输出的相干光的光路中，以漫射相干光，从而消除相干光的相干性。 光电检测器接收由光扩散器扩散的光。

公开(公告)号：US20020193671A1

公开(公告)日：2002-12-19

申请号：US09932185

申请日：2001-08-17

Inventor： Emil W. Ciurczak ,  Kevin P. Bynum ,  Howard Mark

IPC: A61B005/00

CPC classification number: G01J3/28 ,  A61B5/14532 ,  A61B5/1455 ,  A61B5/1495 ,  G01J3/02 ,  G01J3/0232 ,  G01J3/0235 ,  G01J3/0237 ,  G01J3/0254 ,  G01J3/0289 ,  G01J3/10 ,  G01J3/12 ,  G01J2003/1213 ,  G01J2003/1828 ,  G01J2003/2866 ,  G01N21/359 ,  G01N2201/065

Abstract: An individualized modeling equation for predicting a patient's blood glucose values is generated as a function of non-invasive spectral scans of a body part and an analysis of blood samples from the patient, and is stored on a central computer. The central computer predicts a blood glucose value for the patient as a function of the individualized modeling equation and a non-invasive spectral scan generated by a remote spectral device. If the spectral scan falls within the range of the modeling equation, the predicted blood glucose level is output to the patient. If the spectral scan falls outside the range of the modeling equation, regeneration of the model is required, and the patient takes a number of noninvasive scans and an invasive blood glucose level determination. The computer regenerates the individualized modeling equation as a function of the set of spectral scans and corresponding blood glucose values.

Abstract translation: 产生用于预测患者血糖值的个性化建模方程作为身体部位的非侵入性光谱扫描和来自患者的血液样本的分析的函数，并且存储在中央计算机上。 中央计算机根据个性化建模方程和由远程光谱装置产生的非侵入式光谱扫描来预测患者的血糖值。 如果光谱扫描落在建模方程的范围内，则将预测的血糖水平输出给患者。 如果光谱扫描超出建模方程的范围，则需要再生模型，并且患者进行多次无创扫描和侵入性血糖水平测定。 计算机根据光谱扫描集和对应的血糖值重新生成个性化建模方程。

公开(公告)号：US6088117A

公开(公告)日：2000-07-11

申请号：US141727

申请日：1998-08-27

Applicant: Kenji Imura ,  Masayuki Makino ,  Wataru Yamaguchi ,  Hiroshi Kohsaka ,  Naoki Sagisaka

Inventor： Kenji Imura ,  Masayuki Makino ,  Wataru Yamaguchi ,  Hiroshi Kohsaka ,  Naoki Sagisaka

IPC: G01J3/50 ,  G01J1/00 ,  G01J1/42 ,  G01N21/25

CPC classification number: G01N21/255 ,  G01J3/0254 ,  G01N21/474 ,  G01N2201/065

Abstract: A reflection characteristic of a sample is measured using an integrating sphere by: measuring an apparent reflectance of a reference sample by using integrating sphere, the reference sample having a known true reflectance under a given illumination condition; calculating coefficients for rendering a linear combination of a measured apparent reflectance of the reference sample and N-th power (N is 2 or more integer) of the measured apparent reflectance closer to the known true reflectance of the reference sample; storing calculated coefficients in a storage medium as coefficients for the given illumination condition; measuring an apparent reflectance of a desired sample by using the integrating sphere; calculating a true reflectance of the desired sample under the given illumination condition by multiplying the terms of the linear combination of an measured apparent reflectance of the desired sample and N-th power of the measured apparent reflectance of the desired sample by the coefficients stored in the storage medium, respectively.

Abstract translation: 使用积分球来测量样品的反射特性：通过使用积分球来测量参考样品的表观反射率，参考样品在给定照明条件下具有已知的真实反射率; 计算用于渲染参考样本的测量的表观反射率和近似于参考样品的已知真实反射率的测量的表观反射率的N次方（N是2或更大整数）的线性组合的系数; 将计算的系数存储在存储介质中作为给定照明条件的系数; 使用积分球测量所需样品的表观反射率; 通过将所需样品的测量的表观反射率和所需样品的测量的表观反射率的N次方的线性组合的项乘以存储在所需样品中的系数，将所需样品的真实反射率乘以给定照明条件 存储介质。

公开(公告)号：US5838429A

公开(公告)日：1998-11-17

申请号：US855918

申请日：1997-05-14

Applicant: Andreas Hahn

Inventor： Andreas Hahn

IPC: G01N21/25 ,  G01N21/31 ,  G01N33/48 ,  G01J1/04

CPC classification number: G01N21/255 ,  G01N21/3151 ,  G01N2021/3144 ,  G01N2201/0224 ,  G01N2201/0612 ,  G01N2201/064 ,  G01N2201/065

Abstract: The invention relates to an apparatus for measuring physiological parameters of blood conveyed within an extracorporeal circulatory system. Two light sources (1a, 1b) emit light of varying wavelength into a spherical cavity (3) that comprises a reflective inner surface (3a). Light sensor means (2) receives part of the light propagating within the cavity (3). A tube portion of the extracorporeal circulation can be inserted into a second cavity (4) such that the light (La, Lb) emitted by the light sources encounters the boundary surface between the blood and an inner wall of the tube. The light returns to the cavity (3) at least to an extent by means of reflection and/or transmission.

Abstract translation: 本发明涉及一种用于测量在体外循环系统内输送的血液的生理参数的装置。 两个光源（1a，1b）将变化波长的光发射到包括反射内表面（3a）的球形腔（3）中。 光传感器装置（2）接收在空腔（3）内传播的一部分光。 体外循环的管部分可以插入第二腔（4）中，使得由光源发射的光（La，Lb）遇到血液和管的内壁之间的边界面。 光通过反射和/或透射至少在一定程度上返回到空腔（3）。

公开(公告)号：US5748304A

公开(公告)日：1998-05-05

申请号：US687463

申请日：1996-11-04

Applicant: Aimo Heinonen

Inventor： Aimo Heinonen

IPC: G01N21/89 ,  G01J1/02 ,  G01N21/33 ,  G01N21/47 ,  G01N21/88 ,  G01N21/892 ,  G01N21/93 ,  G01N21/00

CPC classification number: G01N21/474 ,  G01N2021/1748 ,  G01N21/33 ,  G01N2201/065

Abstract: A measuring instrument for reflectometric measurements, comprising a spherical measuring chamber (1) provided with a light source (2) and with a specimen aperture (3); a measuring channel (4) which has been provided with optics (5), with a photometer (6), with an optional stop (7) and with an optional filter (8); a reference channel (14) provided with optics (15), with a photometer (16), with an optional stop (17) and with an optional filter (18); and a signal processing and calculating device (20.sub.s, 20.sub.c) for processing and comparing with each other the light intensity values observed by means of the photometers in the measuring and reference channels. As taught by the invention, the measuring instrument comprises at least one visible light light source (2.sub.s) which emits substantially light having a wavelength mainly over about 380 nm, and a UV light source (2.sub.u) which emits substantially light in the UV range having a wavelength mainly under about 380 nm, advantageously 300 to 380 nm.

Abstract translation: PCT No.PCT / FI95 / 00044 Sec。 371日期：1996年11月4日 102（e）日期1996年11月4日PCT 1995年1月30日PCT PCT。 WO95 / 20758 PCT公开号 日期1995年8月3日一种用于反射测量的测量仪器，包括设置有光源（2）和具有试样孔（3）的球形测量室（1）。 具有光学器件（5）的测量通道（4），具有光度计（6），可选的止动件（7）和可选的过滤器（8）; 具有光学器件（15）的参考通道（14），具有光度计（16），具有可选的止动件（17）和可选的过滤器（18）; 以及用于在测量和参考通道中通过光度计观察到的光强度值进行处理和比较的信号处理和计算装置（20s，20c）。 如本发明所教导的，测量仪器包括至少一个可发射基本上具有波长主要在约380nm波长的光的可见光光源（2s），以及在UV范围内基本上发光的UV光源（2u） 主要在约380nm，有利地为300至380nm的波长。

公开(公告)号：US5650843A

公开(公告)日：1997-07-22

申请号：US655654

申请日：1996-05-30

Applicant: Gregory Oscar Moberg ,  Allen Davenport Bellinger ,  Jeffrey George Weber

Inventor： Gregory Oscar Moberg ,  Allen Davenport Bellinger ,  Jeffrey George Weber

IPC: H04N1/028 ,  G01J1/42

CPC classification number: H04N1/0284 ,  H04N1/02815 ,  H04N1/02885 ,  G01N2201/065

Abstract: Feedback control of a spatially distributed light source for a light integrating cavity in which the light acceptance angle of the light feedback device is expanded by means of a light diffuser at the feedback port so as to better average the localized light intensity variations on the internal surface area of the cavity caused by arc wander in the spatially distributed light source.

Abstract translation: 用于光积分腔的空间分布式光源的反馈控制，其中光反馈装置的光接收角通过反射端口处的光扩散器扩展，以便更好地平均内表面上的局部光强度变化 在空间分布的光源中由弧漂移引起的空腔面积。