公开(公告)号：US20120033213A1

公开(公告)日：2012-02-09

申请号：US12853222

申请日：2010-08-09

Applicant: Wei YANG ,  Ming Chai ,  Charlie Zhang ,  Patrick Yang

Inventor： Wei YANG ,  Ming Chai ,  Charlie Zhang ,  Patrick Yang

IPC: G01J3/28

CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0235 ,  G01J3/0291 ,  G01J3/1804

Abstract: A spectrograph having multiple excitation wavelength ranges is disclosed. The spectrograph can include a wavelength switching mechanism to switch between different wavelength ranges in accordance with the wavelength of an incoming light signal. The wavelength switching mechanism can include multiple optical assemblies (or elements) corresponding to the different wavelength ranges for processing the incoming light signal. The mechanism can also include a switching component for switching the optical assemblies to align the appropriate assembly with the incoming light signal. Each optical assembly can include one or more transmission gratings to disperse the incoming light signal into multiple wavelengths within a particular wavelength range and a reflecting mirror proximate to the grating(s) to reflect the wavelengths of light back through the grating(s) to photodetectors for measuring to wavelengths to generate a light spectrum. The spectrograph can be used in Raman spectroscopy.

Abstract translation: 公开了具有多个激发波长范围的光谱仪。 光谱仪可以包括根据入射光信号的波长在不同波长范围之间切换的波长切换机构。 波长切换机构可以包括对应于用于处理入射光信号的不同波长范围的多个光学组件（或元件）。 该机构还可以包括用于切换光学组件以将适当的组件与入射光信号对准的切换部件。 每个光学组件可以包括一个或多个透射光栅以将入射光信号分散在特定波长范围内的多个波长和靠近光栅的反射镜，以将光的波长反射回光栅到光电检测器 用于测量波长以产生光谱。 该光谱仪可用于拉曼光谱。

公开(公告)号：US08098373B2

公开(公告)日：2012-01-17

申请号：US12759082

申请日：2010-04-13

Applicant: Matthew Nelson ,  Patrick Treado ,  Ryan Priore

Inventor： Matthew Nelson ,  Patrick Treado ,  Ryan Priore

IPC: G01J3/28

CPC classification number: G01J3/36 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/027 ,  G01J3/0289 ,  G01J3/0291 ,  G01J3/2823 ,  G01N21/31 ,  G01N2201/0833 ,  G01N2201/0846

Abstract: System and method for spatially and spectrally parallelized FAST. A sample is illuminated to thereby produce interacted photons. The photons are passed through a filter and received at a two-dimensional end of a FAST device wherein said FAST device comprises a two-dimensional array of optical fibers drawn into a one-dimensional fiber stack so as to effectively convert a two-dimensional array of optical fibers into a curvilinear field of view, and wherein said two-dimensional array of optical fibers is configured to receive said photons and transfer said photons out of said fiber array spectral translator device and to a spectrograph through said one-dimensional fiber stack wherein said one-dimensional fiber stack comprises at least two columns of fibers spatially offset in parallel at the entrance slit of said spectrograph. The photons are then detected at a detector to thereby obtain a spectroscopic data set representative of the sample.

Abstract translation: 用于空间和光谱平行化FAST的系统和方法。 照射样品从而产生相互作用的光子。 光子通过过滤器并在FAST装置的二维端接收，其中所述FAST装置包括被拉入一维纤维堆叠的二维光纤阵列，以有效地将二维阵列 的光纤变成曲线视场，并且其中所述二维光纤阵列被配置为接收所述光子并将所述光子从所述光纤阵列光谱转换器装置传送到通过所述一维光纤堆的光谱仪，其中 所述一维纤维堆叠包括在所述光谱仪的入口狭缝处空间上平行偏移的至少两列纤维。 然后在检测器处检测光子，从而获得代表样品的光谱数据集。

公开(公告)号：US08094303B2

公开(公告)日：2012-01-10

申请号：US12986897

申请日：2011-01-07

Applicant: Paul E. Denney ,  Jay R. Eastman ,  Ta-Chieh Huang

Inventor： Paul E. Denney ,  Jay R. Eastman ,  Ta-Chieh Huang

IPC: G01J3/30

CPC classification number: B23K26/032 ,  B23K26/03 ,  B23K26/034 ,  B23K26/043 ,  B23K26/12 ,  B23K26/123 ,  B23K26/128 ,  B23K26/142 ,  B23K26/16 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/0291 ,  G01J3/28

Abstract: A detection system is used during irradiation of an interaction region of a structure with laser light. The structure includes embedded material. The detection system includes means for receiving light emitted from the interaction region. The detection system further includes means for separating the received light into a spectrum of wavelengths. The detection system further includes means for analyzing at least a portion of the spectrum for indications of embedded material within the interaction region.

Abstract translation: 在具有激光的结构的相互作用区域的照射期间使用检测系统。 该结构包括嵌入材料。 检测系统包括用于接收从交互区域发射的光的装置。 检测系统还包括用于将接收的光分离成波长范围的装置。 检测系统还包括用于分析光谱的至少一部分以用于交互区域内的嵌入材料的指示的装置。

公开(公告)号：US08089626B2

公开(公告)日：2012-01-03

申请号：US12226931

申请日：2007-05-01

Applicant: Gavriel J. Iddan

Inventor： Gavriel J. Iddan

IPC: G01J3/28

CPC classification number: G01J3/2803 ,  G01J3/02 ,  G01J3/0259 ,  G01J3/0291 ,  G01J3/12

Abstract: A device and a method for implementing a photo-spectrometer unit (20), or PSU (20), for use with a spectrometry system (100) having optical means (12), and electronic means (13) is disclosed. The PSU is formed in a two-step manufacturing process to form a chip having a monolithic structure. The chip has a first surface and second surface. During the first manufacturing process step, optical means are integrally formed on the first surface (301), and during the second manufacturing process step, electronic means are formed on the second surface (302). The chip is transparent to electromagnetic radiations, and the PSU has at least one optical deflecting element (32) for guiding received radiations through the chip, for establishing direct optical path coupling between an optical element formed on the first surface and an electronic element formed on the second surface.

Abstract translation: 公开了一种用于实现光谱仪单元（20）或PSU（20）的装置和方法，用于具有光学装置（12）和电子装置（13）的光谱测量系统（100）。 PSU以两步制造工艺形成以形成具有整体结构的芯片。 该芯片具有第一表面和第二表面。 在第一制造工艺步骤中，光学装置一体地形成在第一表面（301）上，并且在第二制造工艺步骤期间，电子装置形成在第二表面（302）上。 芯片对于电磁辐射是透明的，并且PSU具有至少一个用于引导接收的辐射通过芯片的光学偏转元件（32），用于在形成在第一表面上的光学元件和形成在第一表面上的电子元件之间建立直接光路耦合 第二个表面。

公开(公告)号：US08068258B2

公开(公告)日：2011-11-29

申请号：US11788929

申请日：2007-04-23

Applicant: Douglas V. Baker ,  John Calow

Inventor： Douglas V. Baker ,  John Calow

IPC: H04N1/21

CPC classification number: G01J3/50 ,  B41J2/2142 ,  G01J3/02 ,  G01J3/0262 ,  G01J3/0264 ,  G01J3/0291 ,  G01J3/52 ,  G01J3/524 ,  G01N21/25 ,  G01N21/276

Abstract: Systems and methods are disclosed for positioning or storing an electro-optical instrument (e.g., spectrophotometer) within a printing device to facilitate calibration or maintenance of the instrument. In various embodiments, the electro-optical instrument may be pivoted or moved to an inclined position to facilitate calibration of the instrument relative to one or more calibration references. The electro-optical instrument may also be moved or inclined along a travel path in the printing device to a position or positions adjacent to various calibration references.

Abstract translation: 公开了用于将电光仪器（例如，分光光度计）定位或存储在打印装置内以便于校准或维护仪器的系统和方法。 在各种实施例中，电光学仪器可以枢转或移动到倾斜位置，以便于相对于一个或多个校准基准来校准仪器。 电光学仪器也可以沿着打印设备中的行进路径移动或倾斜到与各种校准参考相邻的位置或位置。

公开(公告)号：US20110261354A1

公开(公告)日：2011-10-27

申请号：US12668844

申请日：2008-07-14

Applicant: Joseph V. Sinfield ,  Oliver Colic

Inventor： Joseph V. Sinfield ,  Oliver Colic

IPC: G01J3/44

CPC classification number: G01J3/44 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/027 ,  G01J3/0291 ,  G01N21/64 ,  G01N21/65

Abstract: System, method, and apparatus for determining the composition of a sample of material. In one embodiment, the method pertains to the counting of photons that were inelastically scattered by the sample, and for minimizing the effects of fluorescent or phosphorescent photons. In yet another embodiment of the invention, a sample is illuminated by a repetitive pulse of monochromatic light, and the resultant scattered photons from the samples are collected and counted during a predetermined integration period. Yet other embodiments pertain to a low-cost, computer-controlled system for repetitively counting inelastically scattered photons so as to create a Raman histogram and a Raman spectrogram of the photons.

Abstract translation: 用于确定材料样品的组成的系统，方法和装置。 在一个实施方案中，该方法涉及由样品非弹性散射的光子的计数，并且用于使荧光或磷光光子的影响最小化。 在本发明的另一个实施例中，通过单色光的重复脉冲照射样品，并且在预定的积分期间收集并计数来自样品的所得散射光子。 其他实施例涉及用于重复计数非弹性散射的光子的低成本的计算机控制系统，以便产生光子的拉曼直方图和拉曼光谱图。

公开(公告)号：US08045160B2

公开(公告)日：2011-10-25

申请号：US13086065

申请日：2011-04-13

Applicant: Katsumi Shibayama ,  Takafumi Yokino ,  Tomofumi Suzuki ,  Helmut Teichmann ,  Dietmar Hiller ,  Ulrich Starker

Inventor： Katsumi Shibayama ,  Takafumi Yokino ,  Tomofumi Suzuki ,  Helmut Teichmann ,  Dietmar Hiller ,  Ulrich Starker

IPC: G01J3/02 ,  G01J3/18

CPC classification number: G01J3/18 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0237 ,  G01J3/0259 ,  G01J3/0291

Abstract: Alignment marks 12a, 12b, 12c, and 12d are formed on the flat plane 11a of the peripheral edge portion 11 formed integrally with the diffracting layer 8, and when the lens portion 7 is mounted onto the substrate 2, these alignment marks 12a, 12b, 12c and 12d are positioned to the substrate 2, thereby making exact alignment of the diffracting layer 8 with respect to the light detecting portion 4a of the light detecting element 4, for example, not by depending on a difference in curvature radius of the lens portion 7. In particular, the alignment marks 12a, 12b, 12c and 12d are formed on the flat plane 11a, thereby image recognition is given to exactly detect positions of the alignment marks 12a, 12b, 12c and 12d, thus making it possible to make exact alignment.

Abstract translation: 对准标记12a，12b，12c和12d形成在与衍射层8一体形成的周缘部分11的平面11a上，并且当透镜部分7安装到基板2上时，这些对准标记12a，12b ，12c和12d位于基板2上，从而使衍射层8相对于光检测元件4的光检测部分4a精确对准，例如不依赖于透镜的曲率半径的差异 特别地，对准标记12a，12b，12c和12d形成在平面11a上，由此，图像识别被精确地检测对准标记12a，12b，12c和12d的位置，从而可以 准确对齐。

公开(公告)号：US08040507B2

公开(公告)日：2011-10-18

申请号：US12465245

申请日：2009-05-13

Applicant: Katsumi Shibayama

Inventor： Katsumi Shibayama

IPC: G01J3/28

CPC classification number: G01J3/2803 ,  G01J3/02 ,  G01J3/0202 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0243 ,  G01J3/0256 ,  G01J3/0262 ,  G01J3/0291 ,  G01J3/18

Abstract: In the spectrometer 1, a lens portion 3 having a spherical surface 35 on which a spectroscopic portion 4 is provided and a bottom plane 31 in which a light detecting element 5 is disposed, has a side plane 32 substantially perpendicular to the bottom plane 31 and a side plane 34 substantially perpendicular to the bottom plane 31 and the side plane 32. Then, a package 11 that houses a spectroscopy module 10 has side planes 16 and 18 respectively coming into planar-contact with the side planes 32 and 34, and contact portions 22 coming into contact with the spherical surface 35. Therefore, the side planes 32 and 34 of the lens portion 3 are respectively brought into planar-contact with the side planes 16 and 18 of the package 11 while bringing the spherical surface 35 of the lens portion 3 into contact with the contact portions 22 of the package 11, that positions the spectroscopic portion 4 and the light detecting element 5 with respect to a light incident window plate 25 of the package 11.

Abstract translation: 在分光计1中，具有配置有分光部4的球面35的透镜部3和设置有光检测元件5的底面31具有大致垂直于底面31的侧面32， 基本上垂直于底平面31和侧平面32的侧平面34.然后，容纳光谱模块10的封装11具有分别与侧平面32和34平面接触的侧平面16和18，并且接触 部分22与球面35接触。因此，透镜部分3的侧面32和34分别与包装11的侧面16和18平面接触，同时使 透镜部分3与封装11的接触部分22接触，其将分光部分4和光检测元件5相对于封装的光入射窗板25定位 11。

公开(公告)号：US20110205538A1

公开(公告)日：2011-08-25

申请号：US13086065

申请日：2011-04-13

Applicant: Katsumi SHIBAYAMA ,  Takafumi YOKINO ,  Tomofumi SUZUKI ,  Helmut TEICHMANN ,  Dietmar HILLER ,  Ulrich STARKER

Inventor： Katsumi SHIBAYAMA ,  Takafumi YOKINO ,  Tomofumi SUZUKI ,  Helmut TEICHMANN ,  Dietmar HILLER ,  Ulrich STARKER

IPC: G01J3/18

CPC classification number: G01J3/18 ,  G01J3/02 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/0237 ,  G01J3/0259 ,  G01J3/0291

Abstract: Alignment marks 12a, 12b, 12c, and 12d are formed on the flat plane 11a of the peripheral edge portion 11 formed integrally with the diffracting layer 8, and when the lens portion 7 is mounted onto the substrate 2, these alignment marks 12a, 12b, 12c and 12d are positioned to the substrate 2, thereby making exact alignment of the diffracting layer 8 with respect to the light detecting portion 4a of the light detecting element 4, for example, not by depending on a difference in curvature radius of the lens portion 7. In particular, the alignment marks 12a, 12b, 12c and 12d are formed on the flat plane 11a, thereby image recognition is given to exactly detect positions of the alignment marks 12a, 12b, 12c and 12d, thus making it possible to make exact alignment.

Abstract translation: 对准标记12a，12b，12c和12d形成在与衍射层8一体形成的周缘部分11的平面11a上，并且当透镜部分7安装到基板2上时，这些对准标记12a，12b ，12c和12d位于基板2上，从而使衍射层8相对于光检测元件4的光检测部分4a精确对准，例如不依赖于透镜的曲率半径的差异 特别地，对准标记12a，12b，12c和12d形成在平面11a上，由此，图像识别被精确地检测对准标记12a，12b，12c和12d的位置，从而可以 准确对齐。

公开(公告)号：US07990533B2

公开(公告)日：2011-08-02

申请号：US12834370

申请日：2010-07-12

Applicant: John Maier ,  Shona Stewart ,  Jeffrey Cohen

Inventor： John Maier ,  Shona Stewart ,  Jeffrey Cohen

IPC: G01J3/44 ,  G01N21/65

CPC classification number: G01J3/10 ,  A61B5/0071 ,  A61B5/0075 ,  A61B5/417 ,  A61B5/7264 ,  G01J3/02 ,  G01J3/0291 ,  G01J3/0294 ,  G01J3/2823 ,  G01J3/32 ,  G01J3/44 ,  G01J2003/2826 ,  G01N21/65 ,  G01N21/658 ,  G01N2021/656 ,  G01N2201/1293 ,  G01N2201/1296 ,  G02B21/365 ,  G06F19/00 ,  G16H50/70

Abstract: A system and method for determining at least one of: a disease state, a metabolic state, a clinical outcome, and a disease progression of a test renal or prostate sample. A test Raman data set is obtained from the sample wherein said test Raman data set may comprise at least one of a plurality of Raman spectra and a plurality of spatially accurate wavelength resolved Raman images. The test Raman data set is compared to a plurality of reference Raman data sets using a chemometric technique. For analysis of renal samples, each of these reference Raman data sets may have an associated known renal sample and an associated known metabolic state, clinical outcome, and/or disease progression. For analysis of prostate samples, each of these reference Raman data sets may have an associated known prostate sample and an associated known disease state, metabolic state, clinical outcome, and/or disease progression.

Abstract translation: 用于确定测试的肾或前列腺样品的疾病状态，代谢状态，临床结果和疾病进展中的至少一个的系统和方法。 从样品获得测试拉曼数据集，其中所述测试拉曼数据集可以包括多个拉曼光谱和多个空间上准确的波长分辨拉曼图像中的至少一个。 使用化学计量技术将测试拉曼数据集与多个参考拉曼数据集进行比较。 对于肾样品的分析，这些参考拉曼数据集中的每一个可以具有相关联的已知肾样品和相关联的已知代谢状态，临床结果和/或疾病进展。 对于前列腺样品的分析，这些参考拉曼数据集中的每一个可以具有相关联的已知前列腺样品和相关的已知疾病状态，代谢状态，临床结果和/或疾病进展。