Abstract:
The present invention relates to novel systems, devices, and methods comprising spatial light modulators for use in the reading and synthesis of microarrays. For example, the present invention provides micromirror systems for synthesizing and acquiring data from nucleic acid microarrays and systems for collecting, processing, and analyzing data obtained from a microarray.
Abstract:
A non-invasive probe for measuring body components, and a non-invasive body component measurement system including the non-invasive probe is provided. The non-invasive probe includes an input light transferring unit for transferring an input light emitted from a light source; a light splitting unit for splitting the input light into a plurality of living body incident lights; a light condensing unit for condensing the plurality of living body incident lights, so that the plurality of living body incident lights can be irradiated onto a plurality of measuring points, each measuring point corresponding to one of the plurality of living body incident lights; and an output light transferring unit for transferring a plurality of output lights, which each correspond to the one of the plurality of measuring points and, which are obtained by irradiating the plurality of living body incident lights, to a spectrometer that classifies the output lights by wavelength.
Abstract:
An exhaust gas analyzer capable of real-time analysis of the concentration, temperature, and the like of an exhaust gas component in a cross-section of an exhaust path in a spot-wise manner reduces analysis cost. An exhaust gas analyzer (10) comprises sensor units (11) to (14) disposed along the exhaust path, which comprises an exhaust manifold (3) for the engine (2) discharging exhaust gas, an exhaust tube (4), a first catalyst device (5), a second catalyst device (6), a muffler (7), and an exhaust pipe (8). Each sensor unit includes an optical fiber (25) for irradiating the exhaust gas with laser light, and a detector (26) for receiving the laser light emitted by the optical fiber that has been transmitted through the exhaust gas. Based on the laser light received by the detector, the condition of an exhaust gas component, such as its concentration, temperature, and the like, is measured for the analysis of the exhaust gas. The sensor unit has a through-hole (21) allowing the passage of exhaust gas that is formed in a shape matched with a cross-sectional shape of the exhaust path. The infrared laser light R is emitted via the optical fiber (25) into the through-hole (21), travels across the exhaust path, and is then received by the detector (26).
Abstract:
A Raman spectrometry assembly includes a Raman spectrometer having a laser light source and a Raman signal analyzer, an interface module comprising a housing which is connectable to and disconnectable from the spectrometer, and a fiber optic assembly which is connectable to and disconnectable from the interface module, the fiber optic assembly including optical fibers and a probe head at a distal end thereof for disposition adjacent a specimen to be tested, the optical fibers extending from the probe head and adapted to extend to the interface module.
Abstract:
An electromagnetic energy measurement apparatus and method for measuring first, second, and third wavelength components includes first and second coated optical elements having non-parallel surfaces. Proper selection of the parameters of the optical elements reduces the level of coma and astigmatism in the apparatus. Additionally, filters pass the first, second, and third wavelength components to first, second, and third sensors. Improvement in the alignment of the field of view between sensors is realized by applying an adjustable compressive force on the filters to individually adjust the field of view.
Abstract:
The present invention provides a spectral filter for an optical sensor. The spectral filter includes a substrate having a focus region and a defocus region, a panchromatic filter region disposed on the focus region of the substrate and a multi-spectral filter region disposed on the defocus region of the substrate. The panchromatic filter region includes a plurality of panchromatic pixels, while the multi-spectral filter region includes a plurality of multi-spectral pixels. Each of the multi-spectral pixels includes a plurality of color pixels.
Abstract:
An imaging optical system includes a set of mirrors including at least three mirrors on a beam path. Only a last mirror on the beam path has a positive optical power and all other mirrors have negative optical power. The sum of the optical powers of the mirrors is zero. An external posterior aperture stop is on the beam path between the last mirror and the image plane. A back focal length of the optical system is equal to or greater than an effective focal length of the optical system. The field of view is large, and typically at least 30-40 degrees in one plane.
Abstract:
In a spectrometer, preferably in a spectrometric microscope, input light is provided from a light source to a specimen via a source objective element (e.g., a Schwarzchild objective), and the aperture of the light source is matched to the aperture of the source objective element to maximize light throughput to the specimen. The light from the specimen is then collected at a collector objective element and delivered to a camera element, which in turn provides the light to a photosensitive detector. The apertures of the camera element and the collector objective element are also matched to maximize light throughput from the specimen to the detector. As a result, light loss from vignetting effects is reduced, improving the intensity and uniformity of illumination and the sensitivity and accuracy of spectral measurements.
Abstract:
A system and method for managing optical power for controlling thermal alteration of a sample undergoing spectroscopic analysis is provided. The system includes a moveable laser beam generator for irradiating the sample and a beam shaping device for moving and shaping the laser beam to prevent thermal overload or build up in the sample. The moveable laser beam generator includes at least one beam shaping device selected from the group consisting of at least one optical lens, at least one optical diffractor, at least one optical path difference modulator, at least one moveable mirror, at least one Micro-Electro-Mechanical Systems (MEMS) integrated circuit (IC), and/or a liquid droplet. The system also includes an at least two degree of freedom (2 DOF) moveable substrate platform and a controller for controlling the laser beam generator and the substrate platform, and for analyzing light reflected from the sample.
Abstract:
A method of generating a design pattern for a spatial radiation modulator to encode two or more selected spectral components in one or more spectral ranges for the chemometric analysis of a group of analytes. The method includes obtaining a corresponding spectrum for each of the analytes, defining a set of initial spectral windows, constructing a chemometric matrix to relate concentrations of the analytes to intensities of the spectral components, deriving optimized spectral windows, and translating the center wavelength and the bandwidth of each of the optimized spectral windows into a corresponding optimized annular region on the modulator.