-
公开(公告)号:US20220076069A1
公开(公告)日:2022-03-10
申请号:US17415776
申请日:2019-12-16
Applicant: RaySearch Laboratories AB
Inventor: Ola WEISTRAND
Abstract: A method for generating data representing the volume of part of a body, the method comprising generating a point distribution model “PDM” based on an input dataset comprising data representing at least one surface of part of a body, the PDM defining a surface model dataset based on an average dataset and one or more weight-eigenvector pairs, generating a first surface model dataset based on the PDM by modifying at least one weight of the one or more weight-eigenvector pairs, wherein the first surface model dataset is different from the average dataset, and generating an output volume dataset based on the first surface model dataset and a first reference dataset, the first reference dataset comprising data representing the volume of a corresponding part of a body, the output volume dataset comprising data representing a deformed volume of the corresponding part of the body.
-
公开(公告)号:US11170974B2
公开(公告)日:2021-11-09
申请号:US17097199
申请日:2020-11-13
Applicant: RaySearch Laboratories AB
Inventor: Martin Janson
IPC: H01J37/30 , H01J37/05 , H01J37/304
Abstract: It is provided a method for obtaining an energy spectrum of a focused ion beam when a Bragg peak chamber is used to measure an integrated depth dose, IDD. The method comprises the steps of: simulating doses of a set of nominally mono energetic focused ion beams; determining a lateral extension of a Bragg peak chamber to evaluate; calculating a set of theoretic component IDD curves, CIDDs, by laterally integrating the dose of the simulated set of the nominally mono energetic focused ion beams, over the lateral extension of the Bragg peak chamber; storing calculated CIDDs; obtaining a measured IDD of a focused ion beam with a nominal energy using the Bragg peak chamber; and performing a fit of a linear combination of CIDDs to the measured IDD, to determine an energy spectrum for the focused ion beam with the nominal beam energy.
-
公开(公告)号:US11167153B2
公开(公告)日:2021-11-09
申请号:US17058176
申请日:2019-06-10
Applicant: RaySearch Laboratories AB
Inventor: Rasmus Bokrantz , Kjell Eriksson , Tianfang Zhang
IPC: A61N5/10
Abstract: A method of obtaining an interpolated treatment plan is based on interpolating between associated dose distributions through optimization with respect to an optimization problem comprising optimization functions based on deviations from clinical goals. The method may suitably be used to improve navigated plans resulting from multi-criteria optimization.
-
公开(公告)号:US20210205635A1
公开(公告)日:2021-07-08
申请号:US17057170
申请日:2019-05-27
Applicant: RaySearch Laboratories AB
Inventor: Rasmus BOKRANTZ , Albin FREDRIKSSON , Kjell ERIKSSON , Erik ENGWALL , Erik TRANEUS
IPC: A61N5/10
Abstract: The present disclosure generally relates to the field of radiation treatment. More specifically, the present disclosure generally relates to methods and radiation treatment systems for facilitating a multimodal radiation therapy treatment plan, in particular a multimodal radiation therapy plan employing a combined photon beam and electron beam radiation treatment. According to one example embodiment described in the disclosure, a method may comprise obtaining information related to a set of candidate beam types for the combined photon beam and electron beam radiation treatment; comparing the set of candidate beam types against a selection criterion to establish a subset of beam types from the candidate beam types; and generating the combined photon beam and electron beam radiation treatment plan utilizing the thus established subset of beam types.
-
15.
公开(公告)号:US11020616B2
公开(公告)日:2021-06-01
申请号:US16625871
申请日:2018-06-26
Applicant: RaySearch Laboratories AB
Inventor: Erik Engwall , Lars Glimelius , Martin Janson
IPC: A61N5/10
Abstract: According to a first aspect, it is presented a method for determining a treatment plan comprising a distribution of spots for use with ion beam therapy for providing the spots in a target volume. The method comprises the steps of: selecting energy layers to be used in the treatment plan; determining a number of spot sizes to use; generating, for each energy layer, one copy of the energy layer for each spot size to use and populating each copy with spots of the spot size for that copy; optimizing spots of all copies of all energy layers, by repeatedly varying a weight of at least a subset of the spots and calculating an effect on a performance measurement, wherein the performance measurement is calculated by combining a plurality of evaluation criteria, comprising a first criterion related to total treatment time and a second criterion related to a desired dose distribution.
-
公开(公告)号:US20210154492A1
公开(公告)日:2021-05-27
申请号:US16625988
申请日:2018-06-28
Applicant: RaySearch Laboratories AB
Inventor: Erik ENGWALL , Martin JANSON , Lars GLIMELIUS
IPC: A61N5/10
Abstract: It is provided a method for determining ripple filter settings for an ion therapy beam being capable of providing ions of different energy levels to a target volume. The method is performed in a treatment planning system and comprises the steps of: determining at least one beam direction to use to cover a target volume; and assigning a ripple filter setting to each one of a plurality of sub-beams of each one of the at least one beam direction such that each sub-beam is assigned a different ripple filter setting, wherein each ripple filter setting results in a different effect on a Bragg peak width in a direction along the beam, and each energy level is assigned to one of the plurality of sub-beams. The step of assigning a ripple filter setting comprises optimizing based on different filter settings for different sub-beams for each beam direction.
-
17.
公开(公告)号:US10888712B2
公开(公告)日:2021-01-12
申请号:US15567400
申请日:2016-04-11
Applicant: RaySearch Laboratories AB
Inventor: Albin Fredriksson , Erik Engwall
IPC: A61N5/10
Abstract: An optimization method for a radiotherapy plan using robust optimization to handle different scenarios that may occur during one treatment session because of patient movement. The optimization is based on the period and amplitude of the movement, the starting point of the treatment session within a period and the delivery time structure.
-
公开(公告)号:US10549120B2
公开(公告)日:2020-02-04
申请号:US15580765
申请日:2016-06-09
Applicant: RaySearch Laboratories AB
Inventor: Kjell Eriksson
Abstract: An interpolation of deliverable radiotherapy treatment plans is facilitated by restricting the movement of the multi-leaf collimator leaves between optimization steps.
-
公开(公告)号:US10467761B2
公开(公告)日:2019-11-05
申请号:US15738891
申请日:2016-06-23
Applicant: RaySearch Laboratories AB
Inventor: Ola Weistrand
Abstract: A data processing unit receives a reference image (IMG13D) of a deformable physical entity, a target image (IMG23D) of said physical entity, and a first region of interest (ROI13D) defining a first volume in the reference image (IMG13D) representing a reference image element. The reference image (IMG13D), the target image (IMG23D) and the first region of interest (ROI13D) all contain 3D datasets. In response to user commands (c1; c2), the data processing unit defines a first contour (C12D) in a first plane through the target image (IMG23D), which is presented to a user via a display unit together with graphic data reflecting the reference image (IMG13D), the target image (IMG23D) and the first region of interest (ROI13D). The first contour (C12D) is aligned with at least a portion of a first border (IEB1) of a target image element (IE3D) in the target image (IMG23D). The target image element (IE3D) corresponds to the reference image element in the reference image (IMG13D). Based on the first contour (C12D), the target image (IMG23D) and the first region of interest (ROI13D); the data processing unit determines a second region of interest (ROI23D) defining a second volume in the target image (IMG23D).
-
20.
公开(公告)号:US10441812B2
公开(公告)日:2019-10-15
申请号:US15367872
申请日:2016-12-02
Applicant: RaySearch Laboratories AB
Inventor: Rasmus Bokrantz , Björn Hårdemark
IPC: A61N5/10
Abstract: An output radiation treatment plan for at least one target in a treatment volume is determined. Each target is associated with a prescribed radiation dose. An updated treatment plan causes the prescribed radiation dose to be delivered to the target when implemented by a radiation therapy machine. The updated treatment plan requires an updated delivery time to complete and is calculated by: [i] receiving a numerical value designating an upper bound on modulation efficiency of the updated treatment plan, [ii] receiving a current treatment plan, [iii] calculating a current delivery time for the current treatment plan, [iv] calculating an un-modulated delivery time for the current treatment plan, and [v] calculating the updated treatment plan by executing an optimization process while satisfying the upper bound on the modulation efficiency. Steps [ii] to [v] are traversed a predetermined number of times. Thereafter, the output radiation treatment plan is generated.
-
-
-
-
-
-
-
-
-