公开(公告)号：US20100277730A1

公开(公告)日：2010-11-04

申请号：US12769282

申请日：2010-04-28

Applicant: Kazumi Kimura ,  Masayasu Teramura ,  Nobuyuki Tochigi ,  Tokuji Takizawa

Inventor： Kazumi Kimura ,  Masayasu Teramura ,  Nobuyuki Tochigi ,  Tokuji Takizawa

IPC: G01J3/28

CPC classification number: G01J3/02 ,  G01J3/0205 ,  G01J3/0208 ,  G01J3/024 ,  G01J3/50 ,  G01J3/502

Abstract: A spectral colorimetric apparatus for detecting a color of an image of a test subject illuminated includes a stop; a spectral detection optical system for spectrally detecting a beam diffused in the test subject and passing through the stop; and a guiding optical system for guiding, toward the stop, the beam diffused in the test subject, wherein in a first section which is a section including an optical axis of the guiding optical system, condensing positions of the light beam condensed by the guiding optical system change depending on a position in a direction orthogonal to the first section, and the stop is disposed between condensing positions closest to and farthest from the guiding optical system, of condensing positions, in the first section, of the beam condensed by the guiding optical system, in a direction of the optical axis of the guiding optical system.

Abstract translation: 用于检测受检者被照明的图像的颜色的光谱比色装置包括： 光谱检测光学系统，用于光谱检测在测试对象中漫射并通过停止的光束; 以及引导光学系统，用于引导在测试对象中扩散的光束的停止，其中在作为引导光学系统的光轴的部分的第一部分中，由引导光学器件聚光的光束的聚光位置 系统根据与第一部分正交的方向上的位置而改变，并且止动件设置在离引导光学系统最近且最远的聚光位置之间，在第一部分中由导向光学器件聚光的光束的聚光位置 系统，在引导光学系统的光轴的方向上。

公开(公告)号：US07821639B2

公开(公告)日：2010-10-26

申请号：US11961456

申请日：2007-12-20

Applicant: Peter Ehbets ,  Adrian Kohlbrenner

Inventor： Peter Ehbets ,  Adrian Kohlbrenner

IPC: G01J3/46

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/0213 ,  G01J3/024 ,  G01J3/027 ,  G01J3/0278 ,  G01J3/50 ,  G01J3/501 ,  H04N1/00005 ,  H04N1/00015 ,  H04N1/00023 ,  H04N1/00045 ,  H04N1/00047 ,  H04N1/0005 ,  H04N1/00058

Abstract: A scanner device includes a color measuring, a support surface for a measured object and a drive unit for moving the measuring head across the support surface and for adjusting the height of the measuring head in a direction perpendicular to the support surface. The measuring head is equipped with an illuminating channel and a collection channel. The illuminating channel has a light source and optical means for illuminating the measured object at a measurement site at a mean angle of incidence of 45°. The collection channel has optical means for capturing light emanating from the measured object at the measurement site at a mean collection angle of 0° and coupling it into a light guide, which directs the captured light to a wavelength-selective photoelectric transformer, which resolves it into a number of wavelength ranges and generates an electric measurement signal corresponding to each wavelength range.

Abstract translation: 扫描仪装置包括颜色测量，用于测量物体的支撑表面和用于使测量头跨过支撑表面移动并用于在垂直于支撑表面的方向上调节测量头的高度的驱动单元。 测量头配有照明通道和收集通道。 照明通道具有光源和光学装置，用于以45°的平均入射角在测量部位照射被测物体。 采集通道具有光学装置，用于以0°的平均采集角度从测量部位捕获从测量对象发出的光，并将其耦合到光导中，导光板将捕获的光引导到波长选择性光电变压器，其解决它 进入多个波长范围，并产生对应于每个波长范围的电测量信号。

公开(公告)号：US20100219354A1

公开(公告)日：2010-09-02

申请号：US12680964

申请日：2008-10-01

Applicant: Thomas Hennig

Inventor： Thomas Hennig

IPC: G01N21/64

CPC classification number: G01N21/6486 ,  A61B5/0088 ,  G01J3/02 ,  G01J3/0218 ,  G01J3/024 ,  G01J3/10 ,  G01J3/4406 ,  G01J3/508 ,  G01J2003/1213 ,  G01N21/645 ,  G01N2021/6421 ,  G01N2021/6484

Abstract: The invention relates to a device for measuring fluorescent radiation emitted by biological substances, comprising a light source, a capturing unit, an evaluation unit, at least one emission fibre, and at least one detection fibre. Said emission fibre guides excitation radiation to the biological substrate and the detection fibre receives fluorescent radiation and guides it to the evaluation unit. The capturing unit comprises a semiconductor sensor arrangement that detects fluorescent radiation emitted by the biological substance in wave length areas that are separate from each other, are arranged. Data sets of at least two different reference measurements on at least two different biological substances are stored and compared to the measured measurement values to the stored data sets and issues a result relating to the pathological attacks of the examined biological substances and/or relating to the type of examined, biological substances.

Abstract translation: 本发明涉及一种用于测量由生物物质发射的荧光辐射的装置，包括光源，捕获单元，评估单元，至少一种发射光纤和至少一种检测光纤。 所述发射光纤将激发辐射引导到生物衬底，并且检测光纤接收荧光辐射并将其引导到评估单元。 捕获单元包括在彼此分离的波长区域中检测由生物物质发射的荧光辐射的半导体传感器装置。 存储至少两种不同生物物质的至少两种不同参考测量值的数据集，并将其与所测量的测量值进行比较以存储数据集，并发布与所检查的生物物质的病理攻击相关的结果和/或与 检查类型，生物物质。

公开(公告)号：US20100102233A1

公开(公告)日：2010-04-29

申请号：US12530304

申请日：2008-03-05

Applicant: Boris Gelmond

Inventor： Boris Gelmond

IPC: G01N21/17

CPC classification number: G01J3/024 ,  G01N21/3563 ,  G01N21/3581 ,  G01N21/4788

Abstract: A method and apparatus for enhanced THz radiation coupling to molecules, includes the steps of depositing a test material near the discontinuity edges of a slotted member, and enhancing the THz radiation by transmitting THz radiation through the slots. The molecules of the test material are illuminated by the enhanced THz radiation that has been transmitted through the slots, thereby producing an increased coupling of EM radiation in the THz spectral range to said material. The molecules can be bio-molecules, explosive materials, or species of organisms. The slotted member can be a semiconductor film, a metallic film, in particular InSb, or layers thereof. THz detectors sense near field THz radiation that has been transmitted through said slots and the test material.

Abstract translation: 用于增强与分子耦合的THz辐射的方法和装置包括以下步骤：在开槽部件的不连续边缘附近沉积测试材料，以及通过将THz辐射透过狭槽来增强THz辐射。 测试材料的分子被已经通过狭缝传输的增强的THz辐射照射，从而产生在THz光谱范围内的EM辐射与所述材料的增加的耦合。 分子可以是生物分子，爆炸物质或生物物种。 开槽构件可以是半导体膜，金属膜，特别是InSb或其层。 THz检测器检测已经通过所述槽和测试材料传输的近场THz辐射。

公开(公告)号：US20090237647A1

公开(公告)日：2009-09-24

申请号：US12414111

申请日：2009-03-30

Applicant: Masud Azimi ,  Arran Bibby ,  Christopher D. Brown ,  Peili Chen ,  Kevin J. Knopp ,  Daryoosh Vakhshoori ,  Peidong Wang ,  Stephen McLaughlin

Inventor： Masud Azimi ,  Arran Bibby ,  Christopher D. Brown ,  Peili Chen ,  Kevin J. Knopp ,  Daryoosh Vakhshoori ,  Peidong Wang ,  Stephen McLaughlin

IPC: G01N21/00 ,  G01J3/44

CPC classification number: G01J3/02 ,  G01J3/0202 ,  G01J3/024 ,  G01J3/0256 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/0286 ,  G01J3/0291 ,  G01J3/4535 ,  G01N21/552

Abstract: We disclose an apparatus comprising: a hand-portable optical analysis unit including an optical interface; and a device configured to receive and releasably engage the hand-portable optical analysis unit. The device comprises: a housing; a sample unit in the housing; and a resilient member configured to bias the sample unit and the hand-portable analysis unit towards each other when the hand-portable optical analysis unit is received in the device to compress a sample disposed between the sample unit and the optical interface of the optical analysis unit. Methods of analyzing samples are also disclosed.

Abstract translation: 我们公开了一种装置，包括：手持式光学分析单元，包括光学接口; 以及被配置为接收和可释放地接合手持式光学分析单元的设备。 该装置包括：壳体; 壳体中的样品单元; 以及弹性构件，其构造成当所述手持式光学分析单元被接收在所述装置中时，将所述样本单元和所述手持式分析单元朝向彼此偏置，以压缩设置在所述样本单元和所述光学分析的所述光学界面之间的样本 单元。 还公开了分析样品的方法。

公开(公告)号：US20090203991A1

公开(公告)日：2009-08-13

申请号：US12297080

申请日：2006-04-21

Applicant: Thanassis Papaioannou ,  Qiyin Fang ,  Javier A. Jo ,  Laura Marcu ,  K. Kirk Shung

Inventor： Thanassis Papaioannou ,  Qiyin Fang ,  Javier A. Jo ,  Laura Marcu ,  K. Kirk Shung

IPC: A61B5/055 ,  A61B1/00 ,  A61B8/14 ,  A61B6/00

CPC classification number: G01J3/02 ,  A61B5/0035 ,  A61B5/0066 ,  A61B5/0073 ,  A61B5/02007 ,  A61B5/6852 ,  A61B8/0833 ,  A61B8/12 ,  A61B8/4416 ,  A61B8/445 ,  A61B8/4461 ,  G01J3/0202 ,  G01J3/021 ,  G01J3/0218 ,  G01J3/024 ,  G01J3/0264 ,  G01J3/0286 ,  G01J3/0289 ,  G01J3/10

Abstract: The apparatus and methods described herein enable an operator to simultaneously collect images and spectroscopic information from a region(s) of interest using a multiple modality imaging and/or spectroscopic probe, configured as a catheter, endoscope, microscope, or hand held probe. The device may incorporate, for example, an ultrasonic transducer and a fiber optic probe to translate images and spectra. The apparatus and methods may be used in any suitable cavity, for example, the vascular system of a mammal.

Abstract translation: 本文描述的装置和方法使得操作者能够使用被配置为导管，内窥镜，显微镜或手持探针的多模式成像和/或光谱探针同时从感兴趣区域收集图像和光谱信息。 该装置可以包括例如超声波换能器和光纤探针以翻转图像和光谱。 该装置和方法可以用于任何合适的空腔，例如哺乳动物的血管系统。

公开(公告)号：US07551821B2

公开(公告)日：2009-06-23

申请号：US11744797

申请日：2007-05-04

Applicant: Patrick J. Treado ,  Matthew P. Nelson ,  Scott A. Keitzer ,  Ryan D. Smith

Inventor： Patrick J. Treado ,  Matthew P. Nelson ,  Scott A. Keitzer ,  Ryan D. Smith

IPC: G02B6/06 ,  G01J3/44 ,  A61B1/06

CPC classification number: G02B6/06 ,  A61B1/00165 ,  A61B1/043 ,  A61B1/063 ,  A61B1/0638 ,  A61B1/0646 ,  A61B1/07 ,  A61B5/0075 ,  A61B5/0084 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0227 ,  G01J3/024 ,  G01J3/0256 ,  G01J3/0262 ,  G01J3/0286 ,  G01J3/44 ,  G01J2003/1213

Abstract: A fiberscope device is disclosed which is suitable for video imaging, laser Raman spectroscopy and laser Raman spectroscopic (i.e. chemical) imaging. The fiberscope design minimizes fiber background interference arising from the laser delivery fiber optic and the coherent fiber optic light gathering bundle while maintaining high light throughput efficiency through the use of integrated spectral filters. In the fiberscope design, the laser delivery fiber optic is offset from the coherent fiber optic light gathering bundle. The laser delivery field is captured entirely by the light gathering field of view of the coherent fiber bundle. The fiberscope incorporates spectral filter optical elements that provide environmental insensitivity, particularly to temperature and moisture. The fiberscope is suited to the analysis of a wide range of condensed phase materials (solids and liquids), including the analysis of biological materials such as breast tissue lesions and arterial plaques, in such a manner to delineate abnormal from normal tissues.

Abstract translation: 公开了适用于视频成像，激光拉曼光谱和激光拉曼光谱（即化学）成像的纤维内窥镜装置。 纤维镜设计可以最大限度地减少激光传输光纤和相干光纤采集光束产生的光纤背景干扰，同时通过使用集成光谱滤波器保持高光通量效率。 在纤维镜设计中，激光传输光纤与相干光纤聚光束偏移。 激光输送场完全由相干光纤束的聚光场捕获。 纤维镜包含光谱滤光器光学元件，其提供环境不敏感性，特别是对温度和湿度。 纤维内窥镜适用于分析各种凝聚相材料（固体和液体），包括分析生物材料如乳房组织损伤和动脉斑块，以便从正常组织中描绘异常。

公开(公告)号：US07492454B2

公开(公告)日：2009-02-17

申请号：US10530608

申请日：2003-10-07

Applicant: Jean-Charles Hubinois ,  Vincent Lavoine ,  Hervé Chollet

Inventor： Jean-Charles Hubinois ,  Vincent Lavoine ,  Hervé Chollet

IPC: G02B17/06 ,  G01J3/28

CPC classification number: G01J3/28 ,  G01J3/0208 ,  G01J3/024

Abstract: This system collects light emitted by at least one light source (52) and focuses it onto at least one light detection device (54). Preferably, it comprises a first mirror (58) that collects light emitted by the source and focuses it on a second mirror (60) that focuses it in turn onto the device. The system is provided with a chamber that is opaque to all light, particularly ultraviolet radiation, and in which the light source, the light detection device and the mirrors are placed, and means of creating a vacuum in this chamber and filling it with a gas that is transparent to ultraviolet radiation.

Abstract translation: 该系统收集由至少一个光源（52）发射的光并将其聚焦到至少一个光检测装置（54）上。 优选地，其包括第一反射镜（58），其收集由源发射的光并将其聚焦在第二反射镜（60）上，所述第二反射镜将其依次聚焦到所述装置上。 该系统设置有对所有光，特别是紫外线辐射是不透明的室，其中放置有光源，光检测装置和反射镜，以及在该室中产生真空并用气体填充的装置 对紫外线辐射是透明的。

公开(公告)号：US20090040614A1

公开(公告)日：2009-02-12

申请号：US11835294

申请日：2007-08-07

Applicant: Michael J. Hammond

Inventor： Michael J. Hammond

IPC: G02B27/44 ,  G02B5/04

CPC classification number: G01J3/14 ,  G01J3/02 ,  G01J3/0208 ,  G01J3/0229 ,  G01J3/0237 ,  G01J3/024 ,  G01J3/32 ,  G01J2003/062

Abstract: A dispersive filter includes two dispersion systems with an intermediate slit between them. The two dispersion systems have similar but mirror image dispersion characteristics at the plane of the intermediate slit and are configured so that the entrance port of the dispersive filter is polychromatically imaged on the exit port. The intermediate slit passes blocks selected wavelengths and transmits the remaining dispersed wavelengths from the first dispersion system to the second dispersion system. The second dispersion system combines the dispersed beam that passes through the intermediate slit to form an output beam, which is focused on the exit port. In this manner, the radiance of the input radiation is preserved ignoring losses caused by the optical elements and the blocked wavelengths.

Abstract translation: 分散过滤器包括两个在它们之间具有中间狭缝的分散系统。 两个色散系统在中间狭缝的平面上具有类似的镜像色散特征，并且被配置为使得色散滤光器的入口在出射口上被多色成像。 中间狭缝通过块选择的波长并将剩余的分散波长从第一分散系统传输到第二分散系统。 第二色散系统将通过中间狭缝的分散光束组合，形成聚焦在出口上的输出光束。 以这种方式，保留输入辐射的辐射，忽略由光学元件和阻挡波长引起的损耗。

公开(公告)号：US20090015916A1

公开(公告)日：2009-01-15

申请号：US12217851

申请日：2008-07-09

Applicant: Kenji Imura

Inventor： Kenji Imura

IPC: G01N21/00 ,  G01J3/42

CPC classification number: G01J3/02 ,  G01J3/0208 ,  G01J3/0218 ,  G01J3/0237 ,  G01J3/024 ,  G01J3/0289 ,  G01J3/04 ,  G02B23/24 ,  G02B26/0816

Abstract: A light receiving optical system includes: a relay optical system for converging light to be measured which has been converged on an image plane of an objective optical system on a view angle defining aperture for incidence through the view angle defining aperture. The light receiving optical system has the relay optical system with a relay lens operable to be selectively switched between a first and a second conjugated positions, and a first and a second light flux limiting aperture members disposed in proximity to the relay lens in the case where the relay lens is selectively switched between the first and the second conjugated positions. The relay optical system selectively forms, on the image plane of the objective optical system, an enlarged image and a reduced image of the view angle defining aperture in the case where the relay lens is selectively switched between the first and the second conjugated positions to define an incident light flux through the view angle defining aperture by a first and a second light flux limiting apertures, respectively, in the case where the relay lens is selectively switched between the first and the second conjugated positions. A spectrophotometer has the light receiving optical system.

Abstract translation: 光接收光学系统包括：用于会聚已被聚焦在物镜光学系统的像平面上的被测光的中继光学系统，该视场角定义孔通过视角定义孔入射。 光接收光学系统具有中继透镜，其具有可操作以在第一和第二共轭位置之间有选择地切换的中继透镜，以及设置在中继透镜附近的第一和第二光通量限制孔部件， 中继透镜在第一和第二共轭位置之间有选择地切换。 在中继透镜在第一和第二共轭位置之间有选择地切换的情况下，中继光学系统在物镜光学系统的图像平面上选择性地形成放大图像和视角定义孔径的缩小图像，以限定 在中继透镜在第一和第二共轭位置之间有选择地切换的情况下，分别通过第一和第二光通量限制孔分别穿过视角定义孔的入射光束。 分光光度计具有光接收光学系统。