Abstract:
Improved methods, systems and apparatus relating to wide field fluorescence and reflectance imaging are provided, including improved methods, systems and apparatus relating to removal of background signals such as autofluorescence and/or fluorophore emission cross-talk; distance compensation of fluorescent signals; and co-registration of multiple signals emitted from three dimensional tissues.
Abstract:
A printer that incorporates a spectrometry device includes a spectroscope, a distance measurer, and a spectrometry unit. The spectroscope includes a wavelength-selective interference filter on which light from a position of measurement in a medium is incident. The distance measurer measures the distance between the position of measurement and the spectroscope, and the spectrometry unit performs spectrometry at the position of measurement by using the spectroscope and correct a measured value obtained by the spectrometry based on the measured distance.
Abstract:
A confocal measuring apparatus (1) includes a light source (10), an optical system (30) configured to receive reflected light from a measurement surface, a light guide part (20) into which a plurality of cores including a first core (26) and a second core (28) is built and configured to propagate the reflected light by the plurality of cores, a displacement amount measurement part (40) including a spectroscope (42) configured to separate the reflected light propagated by the first core into each wavelength components and a detector (44) having a plurality of light receiving elements arranged to correspond to a spectral direction by the spectroscope, and a peripheral image measurement part (60) configured to form an image of the reflected light propagated by the second core on the plurality of image pickup elements and to generate a peripheral image with respect to a measurement position of the measurement surface.
Abstract:
Disclosed are a snapshot-type polarized hyperspectral camera and an imaging method. The camera comprises polarizers (11), an image sensor (12), and a spectra filter (13). The spectra filter (13) is located on the image sensor (12). The polarizers (11) are located on one side of the image sensor (12). The method comprises: shielding and transmitting incident light by means of polarizers (11), so as to obtain light signals (101) with different polarizing angles; receiving, by means of an image sensor (12), the light signals with different polarizing angles, which are obtained by the polarizers (11), and converting the light signals with different polarizing angles into electric signals (102); and receiving, by means of a spectra filter (13), the electric signals converted by the image sensor (12), and filtering the electric signals, so as to obtain high-frequency electric signals (103) with a preset wavelength. By integrating a spectra filter (13) on a tiled pixel array of a sensor, a rapidly changing scene can be imaged; and meanwhile, by sticking a plurality of polarizers (11) into each channel with a specific wavelength, more exquisite imaging is realized.
Abstract:
A spectrometer includes a light source that emits a beam into a sample volume comprising an absorbing medium. Thereafter, at least one detector detects at least a portion of the beam emitted by the light source. It is later determined, based on the detected at least a portion of the beam and by a controller, that a position and/or an angle of the beam should be changed. The beam emitted by the light source is then actively steered by an actuation element under control of the controller. In addition, a concentration of the absorbing media can be quantified or otherwise calculated (using the controller or optionally a different processor that can be local or remote). The actuation element(s) can be coupled to one or more of the light source, a detector or detectors, and a reflector or reflectors intermediate the light source and the detector(s).
Abstract:
Provided are methods and systems for concurrent imaging at multiple wavelengths. In one aspect, a hyperspectral/multispectral imaging device includes a lens configured to receive light backscattered by an object, a plurality of photo-sensors, a plurality of bandpass filters covering respective photo-sensors, where each bandpass filter is configured to allow a different respective spectral band to pass through the filter, and a plurality of beam splitters in optical communication with the lens and the photo-sensors, where each beam splitter splits the light received by the lens into a plurality of optical paths, each path configured to direct light to a corresponding photo-sensor through the bandpass filter corresponding to the respective photo-sensor.
Abstract:
A printer includes a printing section that ejects an ink, and a spectrometer that disperses incident light. The spectrometer includes a window section that transmits the light, an optical filter device, and a light receiving section. The optical filter device includes a variable wavelength interference filter as a dispersing element that disperses light transmitted by the window section. The light receiving section receives the light which is dispersed by the variable wavelength interference filter. A dirtiness of the window section is detected based on measured values corresponding to each of a plurality of wavelengths obtained by spectrally measuring light from a reference object, and reference values corresponding to each of the plurality of wavelengths.
Abstract:
A system for three-dimensional hyperspectral imaging includes an illumination source configured to illuminate a target object; a dispersive element configured to spectrally separate light received from the target object into different colors; and a light detection and ranging focal plane array (FPA) configured to receive the light from the dispersive element, configured to acquire spatial information regarding the target object in one dimension in the plane of the FPA, configured to acquire spectral information in a second dimension in the plane of the FPA, wherein the second dimension is perpendicular to the first dimension, and configured to obtain information regarding the distance from the FPA to the target object by obtaining times of flight of at least two wavelengths, thereby imaging the target object in three dimensions and acquiring spectral information on at least one 3D point.
Abstract:
A printer incorporating a spectrometry device includes a spectroscope that includes a light receiving optical system including a light receiver which receives reflected light from a range of measurement in a medium, a distance sensor that detects the distance between the medium and the spectroscope, and a reflecting mirror driver and an optical path adjuster that adjust the optical path of the reflected light which is incident on the light receiving optical system from the range of measurement according to the distance detected by the distance sensor.
Abstract:
The present invention may include loading a diagnostic sample onto a sample stage, focusing light from an illumination source disposed on a multi-axis stage onto the diagnostic sample, collecting a portion of light reflected from a surface of the diagnostic sample utilizing a detector, wherein the illumination source and the detector are optically direct-coupled via an optical system, acquiring a set of diagnostic parameters indicative of illumination source position drift from the diagnostic sample, determining a magnitude of the illumination source position drift by comparing the acquired set of diagnostic parameters to an initial set of parameters obtained from the diagnostic sample at a previously measured alignment condition, determining a direction of the illumination source position drift; and providing illumination source position adjustment parameters configured to correct the determined magnitude and direction of the illumination source position drift to the multi-axis actuation control system of the multi-axis stage.