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公开(公告)号：US09295834B2
公开(公告)日：2016-03-29
申请号：US14154413
申请日：2014-01-14
Applicant: Cardiac Pacemakers, Inc.
Inventor： David R. Wulfman , Michael A. Felling
CPC classification number: A61N1/0563 , A61N1/375
Abstract: Various embodiments concern an implantable lead having a coil electrode, configured to deliver defibrillation therapy, made from filars wound in a helical pattern to have a pitch. An end of the coil electrode can be received within a lumen of a tubular fitting, the lumen having threading that corresponds to the pitch of the filars. A wall of a polymer sleeve extending over the coil electrode can be pinched between the threading of the lumen and the filars to mechanically couple the polymer sleeve to the tubular fitting. The polymer sleeve can be porous to permit delivery of the defibrillation through the wall to tissue. Reception of the polymer sleeve within the lumen of the tubular fitting can allow the entire coil electrode to be within the polymer sleeve to prevent direct contact between tissue and the coil electrode.
Abstract translation: 各种实施方案涉及具有线圈电极的可植入引线，该线圈电极被配置为递送由以螺旋形图案缠绕的丝状物制成的除颤疗法以具有间距。 线圈电极的端部可以容纳在管状配件的管腔内，该管腔具有对应于丝状物的间距的线程。 在线圈电极之间延伸的聚合物套筒的壁可以被夹在内腔和丝圈的螺纹之间以将聚合物套管机械地联接到管状配件。 聚合物套管可以是多孔的，以允许将除颤通过壁传递到组织。 在管状配件的管腔内接收聚合物套筒可以允许整个线圈电极在聚合物套筒内，以防止组织和线圈电极之间的直接接触。
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公开(公告)号：US09272135B2
公开(公告)日：2016-03-01
申请号：US14714537
申请日：2015-05-18
Applicant: Cardiac Pacemakers, Inc.
Inventor： David R. Wulfman , Michael A. Felling , Benjamin J. Haasl
CPC classification number: A61N1/0587 , A61N1/05 , A61N1/056 , A61N1/0563 , A61N1/375 , B23K20/002 , B23K31/02 , Y10T29/49171 , Y10T29/49208 , Y10T29/49213
Abstract: Various embodiments concern a lead comprising a cable conductor and a coil electrode having one or more filars, the one or more filars wound in a helical pattern. The lead can further include an inner fitting axially aligned with the coil electrode. The inner fitting can comprise external threading and a slot extending along the inner fitting. The slot can receive a portion of the cable conductor. The lead can include an outer tubular fitting having a lumen with internal threading. Each of the coil electrode and the inner fitting can be partially received within the lumen, both of the external threading and the one or more filars threadedly engaged with the internal threading. The cable conductor can be pinched in the slot to mechanically connect the cable conductor to the inner fitting. The pinching can be supported by the outer tubular fitting.
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公开(公告)号：US09037260B2
公开(公告)日：2015-05-19
申请号：US14154386
申请日：2014-01-14
Applicant: Cardiac Pacemakers, Inc.
Inventor： David R. Wulfman , Michael A. Felling , Benjamin J. Haasl
CPC classification number: A61N1/0587 , A61N1/05 , A61N1/056 , A61N1/0563 , A61N1/375 , B23K20/002 , B23K31/02 , Y10T29/49171 , Y10T29/49208 , Y10T29/49213
Abstract: Various embodiments concern a lead comprising a cable conductor and a coil electrode having one or more filars, the one or more filars wound in a helical pattern. The lead can further include an inner fitting axially aligned with the coil electrode. The inner fitting can comprise external threading and a slot extending along the inner fitting. The slot can receive a portion of the cable conductor. The lead can include an outer tubular fitting having a lumen with internal threading. Each of the coil electrode and the inner fitting can be partially received within the lumen, both of the external threading and the one or more filars threadedly engaged with the internal threading. The cable conductor can be pinched in the slot to mechanically connect the cable conductor to the inner fitting. The pinching can be supported by the outer tubular fitting.
Abstract translation: 各种实施例涉及包括电缆导体和具有一个或多个丝状体的线圈电极的引线，所述一个或多个丝线以螺旋图案缠绕。 引线还可以包括与线圈电极轴向对准的内部配件。 内部配件可以包括外部螺纹和沿着内部配件延伸的狭槽。 槽可以接收电缆导体的一部分。 引线可以包括具有内部螺纹的内腔的外部管状配件。 线圈电极和内部配件中的每一个可以部分地容纳在内腔内，外部螺纹和一个或多个丝线都与内部螺纹螺纹接合。 电缆导体可以被夹在槽中以将电缆导体机械地连接到内部配件。 夹紧可以由外部管状配件支撑。
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公开(公告)号：US20140200640A1
公开(公告)日：2014-07-17
申请号：US14154386
申请日：2014-01-14
Applicant: Cardiac Pacemakers, Inc.
Inventor： David R. Wulfman , Michael A. Felling , Benjamin J. Haasl
IPC: A61N1/05
CPC classification number: A61N1/0587 , A61N1/05 , A61N1/056 , A61N1/0563 , A61N1/375 , B23K20/002 , B23K31/02 , Y10T29/49171 , Y10T29/49208 , Y10T29/49213
Abstract: Various embodiments concern a lead comprising a cable conductor and a coil electrode having one or more filars, the one or more filars wound in a helical pattern. The lead can further include an inner fitting axially aligned with the coil electrode. The inner fitting can comprise external threading and a slot extending along the inner fitting. The slot can receive a portion of the cable conductor. The lead can include an outer tubular fitting having a lumen with internal threading. Each of the coil electrode and the inner fitting can be partially received within the lumen, both of the external threading and the one or more filars threadedly engaged with the internal threading. The cable conductor can be pinched in the slot to mechanically connect the cable conductor to the inner fitting. The pinching can be supported by the outer tubular fitting.
Abstract translation: 各种实施例涉及包括电缆导体和具有一个或多个丝状体的线圈电极的引线，所述一个或多个丝线以螺旋图案缠绕。 引线还可以包括与线圈电极轴向对准的内部配件。 内部配件可以包括外部螺纹和沿着内部配件延伸的狭槽。 槽可以接收电缆导体的一部分。 引线可以包括具有内部螺纹的内腔的外部管状配件。 线圈电极和内部配件中的每一个可以部分地容纳在内腔内，外部螺纹和一个或多个丝线都与内部螺纹螺纹接合。 电缆导体可以被夹在槽中以将电缆导体机械地连接到内部配件。 夹紧可以由外部管状配件支撑。
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公开(公告)号：US11185615B2
公开(公告)日：2021-11-30
申请号：US16598402
申请日：2019-10-10
Applicant: Cardiac Pacemakers, Inc.
Inventor： Joseph T. Delaney, Jr. , David R. Wulfman , Adeniyi O. Aremu , Adegbola O. Adenusi
IPC: A61L31/10 , D01D1/02 , C08G63/183 , A61L27/34 , D01D5/00 , D01F6/62 , C09D7/20 , B05D1/04 , B05D3/04 , C08L67/02 , C09D167/02
Abstract: A method of making a solution including poly(ethylene terephthalate). The method includes dissolving poly(ethylene terephthalate) in a solvent mixture to form a solution, the solvent mixture including two solvent components. A Hansen Solubility Parameter Distance between the solvent mixture and HSP coordinates having a dispersion HSP of 18.02 MPa0.5, a polar HSP of 5.56 MPa0.5, and a hydrogen bonding HSP of 14.27 MPa0.5 is less than about 2 MPa0.5.
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Patent Agency Ranking
公开(公告)号：US20190232573A1
公开(公告)日：2019-08-01
申请号：US16377630
申请日：2019-04-08
Applicant: Cardiac Pacemakers, Inc.
Inventor： David R. Wulfman , Joel T. Eggert , Diana K. Ma
IPC: B29C65/00 , B32B7/04 , B32B27/08 , B29B11/10 , B29C70/42 , B32B27/28 , B29C65/02 , A61N1/05 , B32B27/40 , B32B7/12
CPC classification number: B29C66/712 , A61B2562/12 , A61M25/0009 , A61N1/05 , B29B11/10 , B29C65/02 , B29C65/4895 , B29C66/1222 , B29C66/1224 , B29C66/3034 , B29C66/5221 , B29C66/612 , B29C66/71 , B29C66/7392 , B29C66/7394 , B29C70/42 , B29K2075/00 , B29K2083/00 , B29L2023/007 , B32B7/04 , B32B7/12 , B32B27/08 , B32B27/283 , B32B27/285 , B32B27/288 , B32B27/40 , B32B2255/10 , B32B2255/26 , B32B2262/00 , B32B2535/00 , B32B2597/00 , B29K2071/00
Abstract: An implantable medical device includes a first component including a first material, a second component including a second material, and a fiber matrix including a plurality of fibers. The fiber matrix joins the first component to the second component. The fiber matrix includes a first a first portion connected to the first component, and a second portion connected to the second component. The first portion of the fiber matrix is interpenetrated with, and mechanically fixed to, the first material. The first portion of the fiber matrix directly contacts the first material.
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27.发明授权公开(公告)号：US10111986B2
公开(公告)日：2018-10-30
申请号：US15293583
申请日：2016-10-14
Applicant: Cardiac Pacemakers, Inc.
Inventor： Joseph T. Delaney, Jr. , Niraj Gurung , David R. Wulfman , Adegbola O. Adenusi , Patrick Willoughby , Adeniyi O. Aremu
IPC: A61L31/06 , A61L31/10 , A61N1/05 , C08G81/02 , A61L29/08 , C08G18/66 , C08G18/76 , C08G18/12 , C08G18/24 , C08G18/32
Abstract: A method for making a device including a polyisobutylene-polyurethane block copolymer. The method includes polymerizing a polyisobutylene diol, a diisocyanate, and a chain extender within a solvent system to form a polyisobutylene-polyurethane block copolymer solution, depositing the polyisobutylene-polyurethane block copolymer solution onto at least a portion of the device, and evaporating the solvent system from the deposited polyisobutylene-polyurethane block copolymer solution.
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公开(公告)号：US20180169307A1
公开(公告)日：2018-06-21
申请号：US15843673
申请日：2017-12-15
Applicant: Cardiac Pacemakers, Inc.
Inventor： Mary M. Byron , David R. Wulfman , Angelo Fruci , Adam McGraw , Danielle Frankson , Gregory J. Sherwood , Joseph T. Delaney, JR. , Adeniyi O. Aremu
Abstract: An implantable drug eluting medical device includes a polymer substrate having a surface, a first plurality of nanofibers, and at least one antimicrobial drug. Each of the first plurality of nanofibers includes a first portion interpenetrated with the surface of the substrate to mechanically fix the nanofiber to the substrate, and a second portion projecting from the surface. The at least one antimicrobial drug is disposed within or among the second portion of the first plurality of nanofibers.
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公开(公告)号：US20180043064A1
公开(公告)日：2018-02-15
申请号：US15672674
申请日：2017-08-09
Applicant: Cardiac Pacemakers, Inc.
Inventor： David R. Wulfman , Danielle Frankson , Adeniyi O. Aremu , Angelo Fruci , Gregory J. Sherwood , Mary M. Byron , Joseph T. Delaney, JR. , Adam McGraw
CPC classification number: A61L29/16 , A61F2/30767 , A61F2002/30677 , A61L27/28 , A61L31/046 , A61L31/06 , A61L31/10 , A61L2300/606 , A61L2400/12 , C08L71/02 , C08L75/04 , C08L27/12
Abstract: An implantable medical device includes a polymer substrate and at least one nanofiber. The polymer substrate includes a surface portion extending into the polymer substrate from a surface of the substrate. The at least one nanofiber includes a first portion and a second portion. The first portion is interpenetrated with the surface portion of the substrate, and mechanically fixed to the substrate. The second portion projects from the surface of the substrate.
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公开(公告)号：US20170361061A1
公开(公告)日：2017-12-21
申请号：US15623003
申请日：2017-06-14
Applicant: Cardiac Pacemakers, Inc.
Inventor： Danielle Frankson , Gregory J. Sherwood , David R. Wulfman , Kenneth Gunter , Angelo Fruci , Adam McGraw , Mary M. Byron
CPC classification number: A61M25/0009 , A61L2/02 , A61L27/50 , A61L29/14 , A61L2400/18 , A61L2420/02
Abstract: This disclosure is directed to a medical device including a surface that has been roughened to provide a roughened surface that inhibits the adhesion of microorganisms on the roughened surface.
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