公开(公告)号：US20170100596A1

公开(公告)日：2017-04-13

申请号：US15286663

申请日：2016-10-06

Applicant: Cardiac Pacemakers, Inc.

Inventor： Brian D. Allen ,  David A. Chizek ,  James Michael English ,  Mary M. Byron

IPC: A61N1/375 ,  A61N1/39 ,  A61N1/362 ,  H01R13/52 ,  H01R13/502

CPC classification number: A61N1/3754 ,  A61N1/362 ,  A61N1/3752 ,  A61N1/3956 ,  H01R13/502 ,  H01R13/5224

Abstract: An apparatus including a header mountable to an implantable housing; and an electrically conductive connector block located within the header, wherein the conductive connector block is formed from a substantially non-metallic material.

公开(公告)号：US08988859B2

公开(公告)日：2015-03-24

申请号：US13753023

申请日：2013-01-29

Applicant: Cardiac Pacemakers, Inc.

Inventor： Gregory J. Sherwood ,  Jay E. Daley ,  Mary M. Byron ,  Eric Stemen ,  Peter Jay Kuhn

IPC: H01G9/10 ,  H01G9/045 ,  H01G9/008 ,  H01G9/048 ,  H01G9/052 ,  H01G9/06 ,  H01G9/08 ,  H01G9/14 ,  H01G9/00 ,  H01G9/15 ,  A61N1/375 ,  A61N1/378

CPC classification number: H01G9/045 ,  A61N1/375 ,  A61N1/3782 ,  H01G9/0029 ,  H01G9/008 ,  H01G9/048 ,  H01G9/052 ,  H01G9/06 ,  H01G9/08 ,  H01G9/14 ,  H01G9/15 ,  Y10T29/417

Abstract: This document discusses capacitive elements including a first, second and third electrode arranged in a stack. The third electrode is positioned between the first and second electrode. An interconnect includes a unitary substrate shared with the first and second electrodes. The interconnect is adapted to deform to accommodate the stacked nature of the first and second electrodes. The unitary substrate includes a sintered material disposed thereon.

Abstract translation: 本文讨论了包括以堆叠布置的第一，第二和第三电极的电容元件。 第三电极位于第一和第二电极之间。 互连包括与第一和第二电极共享的整体衬底。 互连件适于变形以适应第一和第二电极的层叠性质。 整体式基板包括设置在其上的烧结材料。

公开(公告)号：US20130141842A1

公开(公告)日：2013-06-06

申请号：US13753023

申请日：2013-01-29

Applicant: Cardiac Pacemakers, Inc.

Inventor： Gregory J. Sherwood ,  Jay E. Daley ,  Mary M. Byron ,  Eric Stemen ,  Peter Jay Kuhn

IPC: H01G9/045 ,  H01G9/15 ,  H01G9/00

CPC classification number: H01G9/045 ,  A61N1/375 ,  A61N1/3782 ,  H01G9/0029 ,  H01G9/008 ,  H01G9/048 ,  H01G9/052 ,  H01G9/06 ,  H01G9/08 ,  H01G9/14 ,  H01G9/15 ,  Y10T29/417

Abstract: This document discusses capacitive elements including a first, second and third electrode arranged in a stack. The third electrode is positioned between the first and second electrode. An interconnect includes a unitary substrate shared with the first and second electrodes. The interconnect is adapted to deform to accommodate the stacked nature of the first and second electrodes. The unitary substrate includes a sintered material disposed thereon.

Abstract translation: 本文讨论了包括以堆叠布置的第一，第二和第三电极的电容元件。 第三电极位于第一和第二电极之间。 互连包括与第一和第二电极共享的整体衬底。 互连件适于变形以适应第一和第二电极的层叠性质。 整体式基板包括设置在其上的烧结材料。

公开(公告)号：US20220211919A1

公开(公告)日：2022-07-07

申请号：US17701421

申请日：2022-03-22

Applicant: Cardiac Pacemakers, Inc.

Inventor： David R. Wulfman ,  Danielle Frankson ,  Adeniyi O. Aremu ,  Angelo Fruci ,  Gregory J. Sherwood ,  Mary M. Byron ,  Joseph T. Delaney, JR. ,  Adam McGraw

IPC: A61L29/16 ,  A61L31/06 ,  A61L31/04 ,  A61L31/10 ,  A61F2/30 ,  A61L27/28

Abstract: An implantable medical device includes a polymer substrate and at least one nanofiber. The polymer substrate includes a surface portion extending into the polymer substrate from a surface of the substrate. The at least one nanofiber includes a first portion and a second portion. The first portion is interpenetrated with the surface portion of the substrate, and mechanically fixed to the substrate. The second portion projects from the surface of the substrate.

公开(公告)号：US11324860B2

公开(公告)日：2022-05-10

申请号：US15672674

申请日：2017-08-09

Applicant: Cardiac Pacemakers, Inc.

Inventor： David R. Wulfman ,  Danielle Frankson ,  Adeniyi O. Aremu ,  Angelo Fruci ,  Gregory J. Sherwood ,  Mary M. Byron ,  Joseph T. Delaney, Jr. ,  Adam McGraw

IPC: A61L29/16 ,  A61L31/06 ,  A61L31/04 ,  A61L31/10 ,  A61F2/30 ,  A61L27/28

Abstract: An implantable medical device includes a polymer substrate and at least one nanofiber. The polymer substrate includes a surface portion extending into the polymer substrate from a surface of the substrate. The at least one nanofiber includes a first portion and a second portion. The first portion is interpenetrated with the surface portion of the substrate, and mechanically fixed to the substrate. The second portion projects from the surface of the substrate.

公开(公告)号：US10335513B2

公开(公告)日：2019-07-02

申请号：US15624102

申请日：2017-06-15

Applicant: Cardiac Pacemakers, Inc.

Inventor： Danielle Frankson ,  Joseph T. Delaney, Jr. ,  Mary M. Byron ,  Adam McGraw ,  David R. Wulfman ,  Kylee M. Lersch

IPC: A61L27/34 ,  A61L27/06 ,  A61L27/04 ,  A61L31/02 ,  A61L31/10 ,  C09D5/16 ,  C09D123/06 ,  C08L71/02

Abstract: A coating for a roughened metal surface of an implantable medical device includes a poly(ethylene glycol) disposed on at least a portion of the roughened metal surface, wherein the poly(ethylene glycol) is covalently bonded directly to the roughened metal surface.

公开(公告)号：US20180085159A1

公开(公告)日：2018-03-29

申请号：US15702928

申请日：2017-09-13

Applicant: Cardiac Pacemakers, Inc.

Inventor： Matthew Sulkin ,  Jason J. Hamann ,  Jacob I. Laughner ,  Mary M. Byron ,  Sarah R. Gutbrod

IPC: A61B18/14

CPC classification number: A61B18/1492 ,  A61B18/1206 ,  A61B18/1233 ,  A61B2017/00022 ,  A61B2017/00053 ,  A61B2017/00123 ,  A61B2017/00561 ,  A61B2018/00166 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00666 ,  A61B2018/00672 ,  A61B2018/00678 ,  A61B2018/00708 ,  A61B2018/00744 ,  A61B2018/00791 ,  A61B2018/00839 ,  A61B2018/00863 ,  A61B2018/00904 ,  A61B2018/00988 ,  A61B2018/1407 ,  A61B2090/065 ,  A61B2217/005 ,  A61B2218/002 ,  A61B2218/007

Abstract: A catheter system includes a catheter and a control system. The catheter includes an elongate catheter body and a catheter tip coupled to a distal end of the elongate catheter body. The catheter tip includes a plurality of openings corresponding to a plurality of lumens extending through the elongate catheter body. The control system is configured to initiate a source of vacuum pressure to at least one of the plurality of lumens, receive an indication of a vacuum seal, and in response to the indication of the vacuum seal, initiate a source of ablation energy.

公开(公告)号：US09180289B2

公开(公告)日：2015-11-10

申请号：US13963559

申请日：2013-08-09

Applicant: Cardiac Pacemakers, Inc.

Inventor： Mary M. Byron ,  Diana Ma ,  James P. Rohl ,  Hood Chatham ,  Frank De Francesco

IPC: A61N1/05 ,  A61L27/18 ,  A61L27/30 ,  A61L27/50 ,  A61L31/06 ,  A61L31/14 ,  A61L31/08

CPC classification number: B05D5/00 ,  A61L27/18 ,  A61L27/306 ,  A61L27/50 ,  A61L31/06 ,  A61L31/08 ,  A61L31/10 ,  A61L31/14 ,  A61L2400/02 ,  A61L2400/10 ,  A61L2400/18 ,  A61L2420/02 ,  A61N1/05 ,  B05D1/62 ,  C23C16/045 ,  C23C16/401 ,  C23C16/505 ,  C23C16/52 ,  C08L83/04

Abstract: An implantable or insertable medical device can include a silicone substrate and a plasma-enhanced chemical vapor deposition coating on the silicone substrate. The coating may include a silicon-containing compound. A method of forming the coating is also provided.

Abstract translation: 可植入或可插入的医疗装置可以包括硅树脂衬底和硅树脂衬底上的等离子体增强化学气相沉积涂层。 涂层可以包括含硅化合物。 还提供了形成涂层的方法。

公开(公告)号：US09119956B2

公开(公告)日：2015-09-01

申请号：US14085735

申请日：2013-11-20

Applicant: Cardiac Pacemakers, Inc.

Inventor： Rajesh Radhakrishnan ,  Mary M. Byron ,  Angelo Fruci ,  Brian Vance

IPC: A61N1/00 ,  A61N1/05 ,  H01J9/02 ,  A61B5/042

CPC classification number: A61N1/05 ,  A61B5/042 ,  A61N1/056 ,  H01J9/02

Abstract: Various embodiments concern an electrode of an implantable medical device for delivering electrical stimulation to tissue. Such an electrode can include a main body formed from a substrate metal comprising one of titanium, stainless steel, a cobalt-chromium alloy, or palladium. The main body may not be radiopaque. The electrode may further include a first coating on at least one side of the main body, the first coating comprising a layer of one of tantalum or iridium metal that is at least about 2 micrometers thick. The first coating can be radiopaque and porous. The porosity of the first coating can increase the electrical performance of the electrode in delivering electrical stimulation to tissue.

Abstract translation: 各种实施例涉及用于将电刺激递送至组织的可植入医疗装置的电极。 这种电极可以包括由包括钛，不锈钢，钴 - 铬合金或钯中的一种的基底金属形成的主体。 主体可能不是不透射线的。 所述电极还可以包括在所述主体的至少一侧的第一涂层，所述第一涂层包含至少约2微米厚的钽或铱金属之一的层。 第一个涂层可以是不透射线和多孔的。 第一涂层的孔隙度可以增加电极在向组织递送电刺激时的电性能。

公开(公告)号：US10933246B2

公开(公告)日：2021-03-02

申请号：US16269845

申请日：2019-02-07

Applicant: Cardiac Pacemakers, Inc.

Inventor： Gregory J. Sherwood ,  Mary M. Byron ,  David R. Wulfman

IPC: A61N1/00 ,  A61N1/375 ,  A61N1/05 ,  A61L31/14 ,  A61L31/16 ,  A61L29/06 ,  A61L29/14 ,  A61L29/16 ,  A61L31/06 ,  A61M5/142 ,  A61N1/39 ,  A61N1/362

Abstract: A method of preventing infection resulting from implanting a medical device. The method includes installing a polymer device at least substantially within a subcutaneous pocket formed to contain a housing of the medical device, and installing the medical device housing in the subcutaneous pocket. The polymer device includes a bioresorbable polymer structure and an antimicrobial agent configured to elute from the polymer structure. The polymer device covers less than about 20% of the surface area of the medical device housing.