公开(公告)号：US20110062323A1

公开(公告)日：2011-03-17

申请号：US12937806

申请日：2009-04-03

Applicant: Jeffery Mark Brown ,  Martin Raymond Green

Inventor： Jeffery Mark Brown ,  Martin Raymond Green

IPC: H01J49/00 ,  H01J49/06

CPC classification number: H01J49/28 ,  H01J49/0072 ,  H01J49/065

Abstract: A mass spectrometer is disclosed comprising an Electron Transfer Dissociation device comprising an ion guide. A control system determines the degree of fragmentation and charge reduction of precursor ions within the ion guide and varies the speed at which ions are transmitted through the ion guide in order to optimise the fragmentation and charge reduction process.

Abstract translation: 公开了一种质谱仪，其包括电子转移离解装置，其包括离子导向器。 控制系统确定离子导向器内的前体离子的碎裂和电荷减少的程度，并且改变离子通过离子导向器传输的速度，以便优化碎裂和电荷还原过程。

公开(公告)号：US20030111948A1

公开(公告)日：2003-06-19

申请号：US09809509

申请日：2001-03-15

Inventor： Michael W. Retsky

IPC: H01J029/00

CPC classification number: H01J29/701 ,  H01J3/30 ,  H01J29/74 ,  H01J37/147 ,  H01J37/153 ,  H01J49/28

Abstract: A method and apparatus is disclosed for electrostatic deflection and focusing of a charged particle stream. The apparatus can include plural vertical and horizontal deflection plates, although a single vertical and a single horizontal deflection plate each with a reference potential plane are preferred. Both orthogonal and preferably tilted display screens are employed to receive the deflected beam. The particle stream is injected offset from a centered position and the stream is deflected asymmetrically relative to the attracting deflection plate. Two alternately preferred computer programs are employable to calculate an offset position. A preferred external quadrupole is employed to correct any residual astigmatism in the particle stream. In one embodiment, the apparatus is disposed in a cathode ray tube. A reduced footprint CRT is also disclosed. Methods and apparatuses for an energy filtered electron beam, a mass spectrometer and a mass separator are also disclosed.

Abstract translation: 公开了一种用于带电粒子流的静电偏转和聚焦的方法和装置。 该装置可以包括多个垂直和水平偏转板，尽管单个垂直和单个水平偏转板各自具有参考电位平面。 采用正交和优选倾斜显示屏幕来接收偏转光束。 颗粒流被注入偏离中心位置，并且流相对于吸引偏转板不对称地偏转。 两个交替优选的计算机程序可用于计算偏移位置。 使用优选的外部四极杆来校正颗粒物流中的任何残余散光。 在一个实施例中，该装置设置在阴极射线管中。 还公开了减少占位面积的CRT。 还公开了能量过滤电子束，质谱仪和质量分离器的方法和装置。

公开(公告)号：US06386374B1

公开(公告)日：2002-05-14

申请号：US09860161

申请日：2001-05-17

Applicant: Robert L. Miller ,  Tihiro Ohkawa ,  Richard L. Freeman

Inventor： Robert L. Miller ,  Tihiro Ohkawa ,  Richard L. Freeman

IPC: B03C130

CPC classification number: H01J49/28

Abstract: A multi-mass filter for separating particles of a multi-species plasma includes a chamber, which defines an axis. A radial electric field is crossed with a magnetic field (E×B) to move the particles of different mass (M1, M2 and M3) on respective trajectories into respective first, second and third regions. Specifically, particles M1 are confined in the first region, while both particles M3 and M2 are ejected from the first region into the second region and only the particles M3 are ejected from the second region into the third region.

公开(公告)号：US4859848A

公开(公告)日：1989-08-22

申请号：US107011

申请日：1987-10-09

Applicant: Ronald R. Bowman ,  Ingvar E. Sodal ,  Thomas A. Wilke ,  Frank Weller

Inventor： Ronald R. Bowman ,  Ingvar E. Sodal ,  Thomas A. Wilke ,  Frank Weller

IPC: G01N27/62 ,  H01J49/06 ,  H01J49/26 ,  H01J49/28 ,  H01J49/32

CPC classification number: H01J49/28 ,  H01J49/32

Abstract: An apparatus is provided for use in determining the components of an inputted gas mixture. The apparatus includes a single piece body or framework preferably made of a high insulating material, such as ceramic. The body includes a number of cut-outs for receiving or incorporating hardware used in generating ions, controlling their movement, and directing them to an ion collector plate. One of the cut-outs formed in the insulating body receives an ion source assembly. Another of the cutouts is a passageway with metallized material coated along the walls thereof for use in generating an electric field. A third cut-out receives and is associated with a magnet assembly used in directing ion movement towards the collector plate. The single body and cut-out construction reduces the number of individual parts, improves the assembly of such parts and reduces adjustment time associated with such parts. The magnetic assembly is formed using pairs of identical parts in a sandwich-like construction to also facilitate assembly of the apparatus. The body also includes a number of feed through holes for receiving conducting pins. The locations of the holes are precisely formed in the body and the conducting pins are used in providing electrical communication between apparatus parts and control hardware.

Abstract translation: 提供了一种用于确定输入的气体混合物的组分的装置。 该装置包括优选由诸如陶瓷的高绝缘材料制成的单件本体或框架。 身体包括多个切口，用于接收或并入用于产生离子的硬件，控制它们的移动，并将它们引导到离子收集板。 在绝缘体中形成的切口之一接收离子源组件。 另一个切口是具有沿其壁涂覆的金属化材料的通道，用于产生电场。 第三切口接收并与用于引导离子向收集板移动的磁体组件相关联。 单体和切口结构减少了单个部件的数量，改进了这些部件的组装，并减少了与这些部件相关联的调整时间。 磁性组件使用夹层结构中的成对相同部件形成，以便于装置的组装。 主体还包括多个用于接收导电销的馈通孔。 孔的位置精确地形成在主体中，并且导电销用于在设备部件和控制硬件之间提供电连接。

公开(公告)号：US4315153A

公开(公告)日：1982-02-09

申请号：US151009

申请日：1980-05-19

Applicant: Richard P. Vahrenkamp

Inventor： Richard P. Vahrenkamp

IPC: H01J49/30 ,  G01N27/62 ,  H01J49/28 ,  G21K1/08 ,  B01D59/44

CPC classification number: H01J49/28

Abstract: The ExB mass separator provides a magnetic field B normal to the beam path and potential plate for applying an electric field normal to the magnetic field for maintaining the selected ions in beam 32 along a defined path. Along the path, after the major portion of the unwanted species are deflected from the beam, focus plates 34 and 36 focus the selected species toward the separator opening 38. Downstream potential plates 28 and 30 maintain the defined path for the selected species.TECHNICAL FIELD

Abstract translation: ExB质量分离器提供垂直于光束路径的磁场B和用于施加垂直于磁场的电场的电位板，用于沿着限定的路径将选定离子保持在梁32中。 沿着路径，在不需要的物质的主要部分从梁偏转之后，聚焦板34和36将所选择的物质聚焦到分离器开口38.下游电位板28和30保持所选物种的限定路径。

公开(公告)号：US20190252172A1

公开(公告)日：2019-08-15

申请号：US16390195

申请日：2019-04-22

Applicant: HIGHLAND INNOVATIONS INC.

Inventor： Eung Joon Jo ,  Yohahn Jo

IPC: H01J49/04 ,  H01J49/00 ,  G06N20/00 ,  G06F16/35

CPC classification number: H01J49/0418 ,  A61B5/7246 ,  G06F16/14 ,  G06F16/355 ,  G06N20/00 ,  H01J49/0036 ,  H01J49/26 ,  H01J49/28

Abstract: Methods, systems, apparatuses, and/or computer programs. Mass spectrometer test data (e.g. a blood sample of a medical patient) may be associated with metadata information. The associated metadata information may be associated with the medical patient. A subset of a sample reference library may be based on the associated metadata information. The sample reference library may include a plurality of sets of mass spectrometer reference data, in accordance with embodiments. Embodiments match the mass spectrometer test data with mass spectrometer reference data of the selected subset of the sample reference library. Embodiments determine characteristic information of a source of the mass spectrometer test data (e.g. the medical patient) based on the known characteristics of the matched mass spectrometer reference data.

公开(公告)号：US09472389B2

公开(公告)日：2016-10-18

申请号：US14440767

申请日：2013-11-15

Applicant: Thermo Fisher Scientific (Bremen) GmbH

Inventor： Michael Krummen ,  Michael Deerberg ,  Johannes Schwieters

IPC: H01J49/28 ,  H01J49/10 ,  H01J49/16

CPC classification number: H01J49/10 ,  H01J49/168 ,  H01J49/28

Abstract: An ion source assembly for a static mass spectrometer, comprises: a mounting element for locating the assembly within the static mass spectrometer; an ion source for generating ions to be analyzed in the static mass spectrometer, the ion source being spaced from the mounting element and arranged to be held in use at a first relatively high potential V1 with respect to the mounting element; and a spacer mounted between the mounting element and the ion source, the spacer arranged to be held in use at a second potential V2 with respect to the mounting element, which is less than the first potential V1.

Abstract translation: 一种用于静态质谱仪的离子源组件，包括：用于将组件定位在静态质谱仪内的安装元件; 用于在所述静态质谱仪中产生要分析的离子的离子源，所述离子源与所述安装元件间隔开并且布置成相对于所述安装元件保持在第一相对高电位V1的使用中; 以及安装在所述安装元件和所述离子源之间的间隔件，所述间隔件布置成相对于所述安装元件保持在使用中的第二电位V2小于所述第一电位V1。

公开(公告)号：US20150357175A1

公开(公告)日：2015-12-10

申请号：US14760639

申请日：2014-01-07

Applicant: LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LIST)

Inventor： Hung Quang Hoang ,  David Dowsett ,  Tom Wirtz

IPC: H01J49/28 ,  H01J49/20 ,  H01J49/02

CPC classification number: H01J49/28 ,  H01J49/025 ,  H01J49/20 ,  H01J49/30

Abstract: The present invention relates to a compact and portable mass spectrometer device comprising a source of ions, a non-scanning magnetic sector for separating ions originating at the source of ions according to their mass-to-charge ratios, and a detection means. The magnetic sector comprises an ion entrance plane and at least two ion exit planes, which allow to optimize the resolving power of the mass spectrometer for specific mass-to charge ratio sub-ranges.

Abstract translation: 本发明涉及一种包括离子源的紧凑且便携的质谱仪装置，以及用于根据其质荷比分离源自离子源的离子的​​非扫描磁性扇区和检测装置。 磁性部分包括离子入射面和至少两个离子出射平面，其允许优化用于特定质量 - 电荷比子范围的质谱仪的分辨能力。

公开(公告)号：US09147561B2

公开(公告)日：2015-09-29

申请号：US14381170

申请日：2013-02-28

Applicant: Inficon GmbH

Inventor： Norbert Rolff

IPC: H01J49/26 ,  H01J49/00

CPC classification number: H01J49/0036 ,  H01J49/0009 ,  H01J49/0031 ,  H01J49/26 ,  H01J49/28

Abstract: A fast method for determining molecular mass using mass spectrometry has the following steps: specifying a first adjusting value (M1) of the mass spectrometer, recording the associated signal amplitude (A1), specifying a second adjusting value (M2) which is different to the first, measuring the associated second signal amplitude (A2), specifying a third adjusting value (M3) which is different to the first (M1) and the second (M2) adjusting value, measuring the associated third signal amplitude (A3), determining a quadratic function containing the measured amplitude values as y-values and the specified adjusting values as x-values, determining the maximum of the quadratic function, wherein the searched adjusting value is determined from the x-value of the maximum.

Abstract translation: 使用质谱法测定分子量的快速方法具有以下步骤：指定质谱仪的第一调整值（M1），记录相关的信号幅度（A1），指定第二调整值（M2），其不同于 首先，测量相关联的第二信号幅度（A2），指定与第一（M1）和第二（M2）调整值不同的第三调整值（M3），测量相关联的第三信号幅度（A3），确定 将测量的振幅值作为y值和指定的调整值作为x值的二次函数，确定二次函数的最大值，其中根据最大值的x值确定搜索到的调整值。

公开(公告)号：US09111654B2

公开(公告)日：2015-08-18

申请号：US14003487

申请日：2012-03-07

Applicant: Kevin Giles ,  Martin Raymond Green ,  Daniel James Kenny ,  David J. Langridge ,  Jason Lee Wildgoose

Inventor： Kevin Giles ,  Martin Raymond Green ,  Daniel James Kenny ,  David J. Langridge ,  Jason Lee Wildgoose

IPC: H01J49/26 ,  G21K1/00 ,  H01J49/42 ,  H01J49/28

CPC classification number: G21K1/00 ,  H01J49/062 ,  H01J49/28 ,  H01J49/427

Abstract: An ion guide is disclosed comprising a plurality of electrodes. A first device is arranged and adapted to apply a RF voltage to at least some of the electrodes in order to form, in use, a pseudo-potential well which acts to confine ions in a first direction within the ion guide. A second device is arranged and adapted to apply a DC voltage to at least some of the electrodes in order to form, in use, a DC potential well which acts to confine ions in a second direction within the ion guide. A third device is arranged and adapted to cause ions having desired or undesired mass to charge ratios to be mass to charge ratio selectively ejected from the ion guide in the second direction.

Abstract translation: 公开了一种离子导向器，其包括多个电极。 第一装置被布置并适于将RF电压施加到至少一些电极，以在使用中形成用于将离子限制在离子导向器内的第一方向上的伪电位阱。 第二装置被布置并适于将DC电压施加到至少一些电极，以在使用中形成用于在离子导向器内沿第二方向限制离子的DC势阱。 第三装置被布置并适于使具有期望或不需要的质量的充电比例的离子成为从第二方向从离子导向器选择性地喷射的质荷比。