Estimation of water interference for spectral correction

    公开(公告)号:US10942117B2

    公开(公告)日:2021-03-09

    申请号:US16160505

    申请日:2018-10-15

    Abstract: A method includes decomposing a training set to obtain a principal component matrix having a plurality of principal component vectors. The method also includes variably rejecting portions of a sample spectrum vector that do not correspond to a selected one of the plurality of principal component vectors by incrementally providing a coefficient indicative of the weighting of the selected principal component vector for selected sub-regions. A corrected spectrum vector can be obtained by excluding certain sub-regions of the sample spectrum vector and corresponding principal component vector, multiplying the sample spectrum vector with the principal component matrix for non-excluded sub-regions, providing a predicted interference vector, and subtracting the predicted interference vector from the sample spectrum vector.

    Intermittent mass spectrometer inlet

    公开(公告)号:US10734213B2

    公开(公告)日:2020-08-04

    申请号:US14908629

    申请日:2014-07-31

    Inventor: Vadym Berkout

    Abstract: An intermittent sample inlet device and methods for use of the intermittent sample inlet device are described that include an orifice plate with an entrance orifice and a rotating skimmer with a skimmer orifice, where the rotating skimmer is disposed between the orifice plate and a vacuum chamber wall. The rotating skimmer rotates so that the skimmer orifice intermittently aligns with the entrance orifice and allows an ion sample to pass through to a mass analyzer.

    Estimation of water interference for spectral correction

    公开(公告)号:US10101269B2

    公开(公告)日:2018-10-16

    申请号:US14446473

    申请日:2014-07-30

    Abstract: A method includes decomposing a training set to obtain a principal component matrix having a plurality of principal component vectors. The method also includes variably rejecting portions of a sample spectrum vector that do not correspond to a selected one of the plurality of principal component vectors by incrementally providing a coefficient indicative of the weighting of the selected principal component vector for selected sub-regions. A corrected spectrum vector can be obtained by excluding certain sub-regions of the sample spectrum vector and corresponding principal component vector, multiplying the sample spectrum vector with the principal component matrix for non-excluded sub-regions, providing a predicted interference vector, and subtracting the predicted interference vector from the sample spectrum vector.

    Ion transfer tube with sheath gas flow

    公开(公告)号:US09953817B2

    公开(公告)日:2018-04-24

    申请号:US15136279

    申请日:2016-04-22

    CPC classification number: H01J49/0404 H01J49/10

    Abstract: An ion transfer tube assembly, a mass spectrometry system, and a method for providing an ion stream to an ion detection device are described that include using an ion transfer tube that provides a coaxial sheath gas flow. In an implementation, an ion transfer tube assembly includes an ion transfer tube for delivering the ion stream, where a sheath gas flows through the ion transfer tube, and where the ion transfer tube receives the ion stream from a first conduit coupled to an ion source; a pump fluidly coupled to the ion transfer tube, where the pump causes the sheath gas to flow through the ion transfer tube, where the ion stream is separated from the ion transfer tube walls by the coaxial sheath gas flow, and where the ion stream is received by a second conduit coupled to the ion detection device.

    Dual spectrometer
    36.
    发明授权

    公开(公告)号:US09869585B2

    公开(公告)日:2018-01-16

    申请号:US14412490

    申请日:2013-07-03

    Abstract: Systems and techniques for optical spectrometer detection using, for example, IR spectroscopy components and Raman spectroscopy components are described. For instance, a system includes a first electromagnetic radiation source configured to illuminate a sample with a first portion of electromagnetic radiation in a first region of the electromagnetic spectrum (e.g., an IR source) and a second electromagnetic radiation source configured to illuminate a sample with a second portion of electromagnetic radiation in a second substantially monochromatic region of the electromagnetic spectrum (e.g., a laser source). The system also includes a detector module configured to detect a sample constituent of a sample by analyzing a characteristic of electromagnetic radiation reflected from the sample associated with the first electromagnetic radiation source and a characteristic of electromagnetic radiation reflected from the sample associated with the second electromagnetic radiation source.

    Ion funnel for efficient transmission of low mass-to-charge ratio ions with reduced gas flow at the exit
    37.
    发明授权
    Ion funnel for efficient transmission of low mass-to-charge ratio ions with reduced gas flow at the exit 有权
    离子漏斗用于在出口处有效地传输低质量 - 电荷比离子并减少气流

    公开(公告)号:US09564305B2

    公开(公告)日:2017-02-07

    申请号:US14445595

    申请日:2014-07-29

    CPC classification number: H01J49/066

    Abstract: A sample inlet device and methods for use of the sample inlet device are described that include an ion funnel having a plurality of electrodes with apertures arranged about an axis extending from an inlet of the ion funnel to an outlet of the ion funnel, the ion funnel including a plurality of spacer elements disposed coaxially with the plurality of electrodes, each of the plurality of spacer elements being positioned between one or two adjacent electrodes, each of the plurality of spacer elements having an aperture with a diameter that is greater than a diameter of each adjacent electrode. The ion funnel is configured to pass an ion sample through the apertures of the electrodes and the spacer elements to additional portions of a detection system, such as to a mass analyzer system and detector.

    Abstract translation: 描述了样品入口装置和使用样品入口装置的方法,其包括具有多个电极的离子漏斗,所述多个电极具有围绕从离子漏斗的入口延伸到离子漏斗的出口的轴线排列的离子漏斗 包括与所述多个电极同轴设置的多个间隔元件,所述多个间隔元件中的每一个位于一个或两个相邻的电极之间,所述多个间隔元件中的每一个具有直径大于 每个相邻电极。 离子漏斗被配置为使离子样品通过电极和间隔元件的孔通过检测系统的附加部分,例如质量分析器系统和检测器。

    CONSTANT POWER SUPPLY FOR A RESISTIVE LOAD
    38.
    发明申请
    CONSTANT POWER SUPPLY FOR A RESISTIVE LOAD 审中-公开
    恒定电源用于电阻负载

    公开(公告)号:US20160172855A1

    公开(公告)日:2016-06-16

    申请号:US14903667

    申请日:2014-07-08

    Inventor: Leonard Cardillo

    Abstract: Systems and techniques for supplying constant electrical power within component tolerances to a resistively changing load in an electrical circuit are described. A method includes receiving an indication of a characteristic voltage associated with a load in an electrical circuit. The method also includes receiving an indication of a characteristic current associated with the load, where the indication of the characteristic current is received as an indication of a second characteristic voltage. The method further includes determining a power consumption associated with the load based upon the indication of the characteristic voltage and the indication of the characteristic current. The method also includes adjusting at least one of a voltage or a current supplied to the load based upon the power consumption associated with the load and a desired constant power consumption for the load.

    Abstract translation: 描述了将元件公差内的恒定电力提供给电路中的电阻变化负载的系统和技术。 一种方法包括接收与电路中的负载相关联的特征电压的指示。 该方法还包括接收与负载相关联的特征电流的指示,其中接收到特征电流的指示作为第二特征电压的指示。 该方法还包括基于特征电压的指示和特征电流的指示来确定与负载相关联的功率消耗。 该方法还包括基于与负载相关联的功率消耗和负载的期望的恒定功率消耗来调整提供给负载的电压或电流中的至少一个。

    Transmission raman sample analysis
    39.
    发明授权
    Transmission raman sample analysis 有权
    传输拉曼样本分析

    公开(公告)号:US09354178B2

    公开(公告)日:2016-05-31

    申请号:US14198056

    申请日:2014-03-05

    CPC classification number: G01N21/65

    Abstract: Systems and methods for analyzing samples in containers are provided, where an emitter emits radiation at a first location on the container, with a portion of the radiation passing through the container and into the sample, some of the radiation is reflected within the container, a detector receives a transmission Raman signal including Raman radiation from multiple portions of the sample, and a comparator compares the transmission Raman signal with the radiation emitted by the emitter.

    Abstract translation: 提供了用于分析容器中的样品的系统和方法,其中发射器在容器上的第一位置处发射辐射,其中一部分辐射通过容器并进入样品,一些辐射在容器内反射, 检测器从样品的多个部分接收包括拉曼辐射的透射拉曼信号,并且比较器将透射拉曼信号与发射器发射的辐射进行比较。

    UBIQUITOUS TRANSMISSIVE RAMAN SPECTROSCOPY FOR STAND-OFF DETECTION
    40.
    发明申请
    UBIQUITOUS TRANSMISSIVE RAMAN SPECTROSCOPY FOR STAND-OFF DETECTION 审中-公开
    UBIQUITOUS传输拉曼光谱用于定位检测

    公开(公告)号:US20160084765A1

    公开(公告)日:2016-03-24

    申请号:US14495295

    申请日:2014-09-24

    CPC classification number: G01N21/65 G01J3/0291 G01J3/44

    Abstract: A substance analysis system and method are provided, the system disposable a variable stand-off distance from a substance in situ, including an emitter disposed to emit radiation onto the substance in situ, and a detector disposed the variable stand-off distance from the substance in situ, the detector comprising a receiver defining a substantially collimated collection path over the variable stand-off distance.

    Abstract translation: 提供了一种物质分析系统和方法,所述系统一次性与原位物质的可变间隔距离,包括设置成将原子辐射放射到物质上的发射器,以及设置与物质的可变间隔距离的检测器 在原位,检测器包括限定可变间隔距离上的基本上准直的收集路径的接收器。

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