中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

62 records (took 0.015 seconds)

    System and method for dynamic chemical imaging
    32.
    发明申请
    System and method for dynamic chemical imaging 有权
    动态化学成像系统和方法

    公开(公告)号：US20060268267A1

    公开(公告)日：2006-11-30

    申请号：US11399032

    申请日：2006-04-06

    Applicant: Thomas Voigt ,  David Tuschel ,  John Maier

    Inventor： Thomas Voigt ,  David Tuschel ,  John Maier

    IPC: G01J3/44

    CPC classification number: G01N21/6456 ,  G01J3/12 ,  G01J3/1256 ,  G01J3/2823 ,  G01J3/32 ,  G01J3/44 ,  G01J2003/1269 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/65

    Abstract: A system and method for detecting dynamic changes that occur in a sample between a first time interval and a second time interval using a series of at least first and second sequential chemical images of the sample. During the first time interval: (i) the sample is illuminated with a plurality of photons to thereby produce photons scattered or emitted by the sample; (ii) a two-dimensional array of detection elements is used to simultaneously detect scattered or emitted photons in a first predetermined wavelength band from different locations on or within the sample; and (iii) the two-dimensional array of detection elements is thereafter used one or more further times to simultaneously detect scattered or emitted photons in one or more further predetermined wavelength band(s) from different locations on or within the sample. The outputs of the two-dimensional array of detection elements during the first time interval are then combined to generate the first chemical image of the sample. The process is repeated during the second time interval to generate the second chemical image of the sample. Dynamic changes occurring in the sample between the first time interval and the second time interval are detected based on one or more differences between the first and second chemical images.

    Abstract translation: 一种系统和方法，用于使用所述样本的至少第一和第二顺序化学图像的一系列来检测在第一时间间隔和第二时间间隔之间在样本中发生的动态变化。 在第一时间间隔期间：（i）样品用多个光子照射，从而产生样品散射或发射的光子; （ii）检测元件的二维阵列用于同时从样品上或样品内的不同位置检测来自第一预定波长带的散射或发射的光子; 然后，（iii）检测元件的二维阵列此后再被使用一次或多次，以同时检测来自样品上或样品内的不同位置的一个或多个另外的预定波长带中的散射或发射的光子。 然后组合在第一时间间隔期间检测元件的二维阵列的输出以产生样本的第一化学图像。 该过程在第二时间间隔期间重复以产生样品的第二化学图像。 基于第一和第二化学图像之间的一个或多个差异来检测在第一时间间隔和第二时间间隔之间在样本中发生的动态变化。

    Method and apparatus for interactive hyperspectral image subtraction
    33.
    发明申请
    Method and apparatus for interactive hyperspectral image subtraction 审中-公开
    交互式高光谱图像减法的方法和装置

    公开(公告)号：US20060221335A1

    公开(公告)日：2006-10-05

    申请号：US11097160

    申请日：2005-04-04

    Applicant: Arjun Bangalore ,  David Tuschel

    Inventor： Arjun Bangalore ,  David Tuschel

    IPC: H01L27/00 ,  G01J3/44 ,  G01N21/65

    CPC classification number: G01J3/44 ,  G01J3/2823 ,  G01N21/65

    Abstract: The disclosure relates to method and apparatus for interactive hyperspectral image subtraction. In one embodiment, the disclosure relates to a method for obtaining a spectral image of a first specie from a frame of a plurality of pixels defining a composition of the first specie with a second specie. The method may include (i) identifying, for each of the first and second species, an appropriate Raman wavelength; (ii) defining at least one background wavelength for the frame; (iii) identifying pixels defined only by background wavelength; (iv) identifying pixels defined only by the first specie or the second specie; (v) identifying the remaining pixels, the remaining pixels defined by at least a combination of the first and second species; and (vi) forming a spectral image for the first specie.

    Abstract translation: 本公开涉及用于交互式高光谱图像减法的方法和装置。 在一个实施例中，本发明涉及一种从多个像素的帧中获得第一物体的光谱图像的方法，所述多个像素的像素定义了具有第二物体的第一物体的组成。 该方法可以包括（i）为第一和第二种类中的每一种识别适当的拉曼波长; （ii）为所述帧定义至少一个背景波长; （iii）识别仅由背景波长定义的像素; （iv）识别仅由第一物种或第二物种定义的像素; （v）识别剩余像素，由至少第一和第二种类的组合限定的剩余像素; 和（vi）形成第一种物质的光谱图像。

    System and method for dynamic chemical imaging
    34.
    发明申请
    System and method for dynamic chemical imaging 有权

    公开(公告)号：US20060001870A1

    公开(公告)日：2006-01-05

    申请号：US10882082

    申请日：2004-06-30

    Applicant: Thomas Voigt ,  David Tuschel ,  John Maier

    Inventor： Thomas Voigt ,  David Tuschel ,  John Maier

    IPC: G01J3/44

    CPC classification number: G01N21/6456 ,  G01J3/12 ,  G01J3/1256 ,  G01J3/2823 ,  G01J3/32 ,  G01J3/44 ,  G01J2003/1269 ,  G01N21/3563 ,  G01N21/3577 ,  G01N21/65

    Abstract: A system and method for detecting dynamic changes that occur in a sample between a first time interval and a second time interval using a series of at least first and second sequential chemical images of the sample. During the first time interval: (i) the sample is illuminated with a plurality of photons to thereby produce photons scattered or emitted by the sample; (ii) a two-dimensional array of detection elements is used to simultaneously detect scattered or emitted photons in a first predetermined wavelength band from different locations on or within the sample; and (iii) the two-dimensional array of detection elements is thereafter used one or more further times to simultaneously detect scattered or emitted photons in one or more further predetermined wavelength band(s) from different locations on or within the sample. The outputs of the two-dimensional array of detection elements during the first time interval are then combined to generate the first chemical image of the sample. The process is repeated during the second time interval to generate the second chemical image of the sample. Dynamic changes occurring in the sample between the first time interval and the second time interval are detected based on one or more differences between the first and second chemical images.

    Method and apparatus for dark field chemical imaging
    35.
    发明申请
    Method and apparatus for dark field chemical imaging 有权
    暗场化学成像方法和装置

    公开(公告)号：US20060001869A1

    公开(公告)日：2006-01-05

    申请号：US10879636

    申请日：2004-06-30

    Applicant: David Tuschel ,  Wesley Hutchison ,  Myles Berkman

    Inventor： David Tuschel ,  Wesley Hutchison ,  Myles Berkman

    IPC: G01J3/44 ,  G01N21/65

    CPC classification number: G01N21/65 ,  G01J3/0227

    Abstract: The disclosure is generally directed to a method and apparatus for providing an image of a sample. The apparatus includes an illuminating source for transmitting photons to a sample. The transmitted photons illuminate the sample or are scattered upon reaching the sample. A lens collects the scattered photons and transmits the scattered photons to a tunable filter for forming an image. The illuminating photons traveling from the illuminating source to the sample do not pass through the lens.

    Abstract translation: 本公开一般涉及用于提供样品图像的方法和装置。 该装置包括用于将光子传送到样品的照明源。 透射的光子照射样品或在到达样品时散射。 透镜收集散射的光子并将散射的光子传输到可调滤光器以形成图像。 从照明光源传播到样品的照明光子不能通过透镜。

    CRYSTALLINE COLLOIDAL ARRAY DEEP UV NARROW BAND RADIATION FILTER
    37.
    发明申请
    CRYSTALLINE COLLOIDAL ARRAY DEEP UV NARROW BAND RADIATION FILTER 审中-公开
    水晶胶带阵列深紫外线带辐射滤光片

    公开(公告)号：US20120062883A1

    公开(公告)日：2012-03-15

    申请号：US13227066

    申请日：2011-09-07

    Applicant: Sanford A. Asher ,  Luling Wang ,  David Tuschel

    Inventor： Sanford A. Asher ,  Luling Wang ,  David Tuschel

    IPC: G01J3/44 ,  G01J3/28 ,  G02B5/20 ,  C07F7/18 ,  C08G77/28

    CPC classification number: C08G77/28 ,  G01J3/32 ,  G01J3/44 ,  G01J2003/1213 ,  G02B5/208

    Abstract: The present invention provides a method of making highly charged, monodisperse particles which do not absorb deep ultraviolet (UV) light and a method of making crystalline colloidal array (CCA) deep UV narrow band radiation filters by using these highly charged monodisperse particles. The CCA filter rejects and/or selects particular regions of the electromagnetic spectrum while transmitting adjacent spectral regions. The filtering devices of the present invention are wavelength tunable over significant spectral intervals by changing the incident angle of the CCA filter relative to the light. Larger wavelength changes can be obtained by changing the concentrations of particles in the CCAs. The present invention also includes applications of the CCA filter to hyperspectral imaging and Raman imaging devices.

    Abstract translation: 本发明提供了一种制造不吸收深紫外（UV）光的高电荷单分散颗粒的方法，以及通过使用这些高电荷单分散颗粒制造结晶胶体阵列（CCA）深UV窄带辐射过滤器的方法。 CCA滤波器在传输相邻光谱区域的同时拒绝和/或选择电磁光谱的特定区域。 本发明的滤波器件通过改变CCA滤波器相对于光的入射角度，可以在显着的光谱间隔上波长可调。 通过改变CCA中的颗粒浓度可以获得更大的波长变化。 本发明还包括CCA滤波器对高光谱成像和拉曼成像装置的应用。

    METHOD AND APPARATUS FOR INTERACTIVE HYPERSPECTRAL IMAGE SUBTRACTION
    38.
    发明申请
    METHOD AND APPARATUS FOR INTERACTIVE HYPERSPECTRAL IMAGE SUBTRACTION 有权

    公开(公告)号：US20090066947A1

    公开(公告)日：2009-03-12

    申请号：US12211960

    申请日：2008-09-17

    Applicant: Arjun S. Bangalore ,  David Tuschel

    Inventor： Arjun S. Bangalore ,  David Tuschel

    IPC: G01N21/31 ,  G06K9/00

    CPC classification number: G01N21/31 ,  G01N21/6456 ,  G01N21/65 ,  G01N2021/178

    Abstract: Disclosed is a method of obtaining a spectral image of each of a plurality of predetermined chemical species in a sample, comprising: (a) illuminating the sample with a first plurality of photons to produce a second plurality of photons; (b) collecting the second plurality of photons and producing a plurality of images of the sample therefrom, each of said images comprising a frame consisting essentially of a plurality of pixels; (c) for each of the predetermined chemical species, identifying at least one wavelength range at which the chemical specie exhibits a unique absorption of radiation; (d) identifying at least one wavelength range at which none of the predetermined chemical species exhibits an absorption of radiation; (e) in each of the image frames, identifying which of the pixels do not contain any of the predetermined chemical species; (f) in each of the image frames, identifying which of the pixels contain only a first the predetermined chemical species; (g) repeating the previous step for each of the predetermined chemical species; (h) in each of the image frames, identifying which of the pixels contain more than one of the predetermined chemical species; (i) for each pixel that contains more than one of the predetermined chemical species, separating the contribution of each predetermined chemical species; and (j) composing separate spectral images of each of the predetermined chemical species in the sample. Also disclosed are apparati for performing these methods, comprising: (a) an illumination source for illuminating the sample with a first plurality of photons to form a second plurality of photons; (b) an optical device for receiving and directing the second plurality of photons to an imaging device; (c) an imaging device for forming a plurality of images of the sample; and (d) a processor in communication with the imaging device.

    Method and apparatus for a microscope image selector
    39.
    发明授权
    Method and apparatus for a microscope image selector 有权
    显微镜图像选择器的方法和装置

    公开(公告)号：US07414725B2

    公开(公告)日：2008-08-19

    申请号：US11902874

    申请日：2007-09-26

    Applicant: Xinghua Wang ,  Thomas Voigt ,  David Tuschel ,  Chenhui Wang ,  Patrick Treado

    Inventor： Xinghua Wang ,  Thomas Voigt ,  David Tuschel ,  Chenhui Wang ,  Patrick Treado

    IPC: G01N21/25 ,  G02B21/00

    CPC classification number: G01N21/65 ,  G01J3/02 ,  G01J3/0291 ,  G01J3/36 ,  G01J3/44 ,  G01N21/359 ,  G01N21/59 ,  G01N21/6458 ,  G01N2021/6419 ,  G01N2021/6421 ,  G01N2021/656

    Abstract: The disclosure generally relates to a multimode imaging apparatus for simultaneously obtaining multiple wavelength-discriminative spectral images of a sample. In one embodiment, the apparatus includes an image selector having a rotator assembly, the rotator assembly housing a first plurality of optical components, the image selector adapted to receive a illuminating photons having a first wavelength and direct the illuminating photons to the sample, the image selector adapted to receive illuminating photons interacted with the sample and selectively direct said interacted photons to one of a plurality of detection sources; a microscope turret housing a second plurality of components, the microscope turret adapted to receive illuminating photons having a second wavelength and direct the photons to the sample; the microscopic turret adapted to receive illuminating photons interacted with the sample and selectively direct said interacted photons to one of a plurality of detection sources; wherein substantially all of the interacted photons are selectively directed one of a plurality of detection sources to form multiple wavelength discriminative spectral images of the sample simultaneously.

    Abstract translation: 本公开总体上涉及用于同时获得样本的多个波长鉴别光谱图像的多模式成像装置。 在一个实施例中，该装置包括具有旋转器组件的图像选择器，旋转体组件容纳第一多个光学部件，图像选择器适于接收具有第一波长的照明光子并将照射光子引导到样本，图像 选择器，适于接收与样本相互作用的照明光子，并选择性地将所述相互作用的光子引导到多个检测源之一; 显微镜转台，其容纳第二多个部件，所述显微镜转台适于接收具有第二波长并且将所述光子引导到所述样品的照明光子; 适于接收与样品相互作用的照明光子并且选择性地将所述相互作用的光子引导到多个检测源中的一个的微观炮塔; 其中基本上所有相互作用的光子被选择性地指向多个检测源中的一个，以同时形成样品的多个波长鉴别光谱图像。

Patent Agency Ranking