公开(公告)号：US20180104327A1

公开(公告)日：2018-04-19

申请号：US15511988

申请日：2015-09-18

Applicant: Japan Science and Technology Agency

Inventor： Yoshihiro KAWAOKA ,  Tokiko WATANABE ,  Eiryo KAWAKAMI ,  Shinji WATANABE

IPC: A61K39/145 ,  C12N5/10 ,  C12N5/071 ,  C12N7/02 ,  C12N15/113 ,  C12N7/08

CPC classification number: A61K39/145 ,  C12N5/00 ,  C12N5/0686 ,  C12N5/10 ,  C12N7/02 ,  C12N7/08 ,  C12N15/113 ,  C12N2760/16051

Abstract: The present invention provides cells which have a high ability to propagate influenza virus, are suitable for use in production of an influenza virus for preparing a vaccine, and are able to be cultured in vitro, and a method for producing an influenza virus using the cells. That is, the present invention provides cells for producing an influenza virus in which expression of one or more genes that encode proteins involved in an effect of suppressing influenza virus production in a cell is suppressed and the gene is at least one selected from the group including ACTG1 gene and the like, and a method for producing an influenza virus that includes infecting the cells for producing an influenza virus with an influenza virus and then culturing.

公开(公告)号：US09929188B2

公开(公告)日：2018-03-27

申请号：US14357138

申请日：2012-11-07

Applicant: Japan Science and Technology Agency

Inventor： Tatsuya Shimoda ,  Toshihiko Kaneda

IPC: B44C1/22 ,  H01L27/12 ,  H01L45/00 ,  H01L41/09 ,  H01L41/317 ,  H01L41/332 ,  H01L29/786 ,  B41J2/16 ,  H01L21/67 ,  H01L27/108 ,  H01L21/28 ,  H01L29/78 ,  H01L49/02

CPC classification number: H01L27/1255 ,  B41J2/161 ,  B41J2/1623 ,  B41J2/1628 ,  B41J2/1629 ,  B41J2/1637 ,  B41J2/1645 ,  H01L21/28291 ,  H01L21/67098 ,  H01L27/10805 ,  H01L27/10873 ,  H01L27/1262 ,  H01L27/127 ,  H01L28/55 ,  H01L29/78391 ,  H01L29/7869 ,  H01L41/0973 ,  H01L41/317 ,  H01L41/332 ,  H01L45/1206 ,  H01L45/1226 ,  H01L45/147 ,  H01L45/1608

Abstract: According to the present invention, a method of producing a functional device includes the imprinting step and the functional solid material layer formation step. In the imprinting step, a functional solid material precursor layer obtained from a functional solid material precursor solution as a start material is imprinted so that a first temperature of a heat source for supplying heat to the functional solid material precursor layer is higher than a second temperature of the functional solid material precursor layer in at least part of a time period while a mold for forming an imprinted structure is pressed against the functional solid material precursor layer. In the functional solid material layer formation step, after the imprinting step, the functional solid material precursor layer is heat treated at a third temperature higher than the first temperature in an atmosphere containing oxygen to form a functional solid material layer from the functional solid material precursor layer.

公开(公告)号：US20180069534A1

公开(公告)日：2018-03-08

申请号：US15558059

申请日：2016-03-24

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Satoshi Sugahara ,  Shuichiro Yamamoto

IPC: H03K3/3565 ,  G11C11/413 ,  G11C11/412 ,  H02M7/42

CPC classification number: H03K3/3565 ,  G11C5/148 ,  G11C11/412 ,  G11C11/413 ,  G11C14/0054 ,  H02M7/42 ,  H03K3/02337 ,  H03K3/356

Abstract: An electronic circuit includes: a bistable circuit connected between first and second power sources respectively supplied with first and second power-supply voltages and including first and second inverters connected in a loop being inverter circuits switching between first and second modes; a control circuit outputting first and second signals respectively setting the inverter circuits in the first and second modes to the inverter circuits; and a power-supply circuit supplying a first voltage as a power-supply voltage while the inverter circuits are in the first mode, and supplying a second voltage higher than the first voltage as the power-supply voltage while the inverter circuits are in the second mode, wherein the first mode exhibits hysteresis in a transfer characteristic curve and the second mode exhibits no hysteresis in a transfer characteristic curve, and/or the first mode has a steeper transfer characteristic curve than the second mode.

公开(公告)号：US09902623B2

公开(公告)日：2018-02-27

申请号：US14379218

申请日：2013-02-18

Applicant: Japan Science and Technology Agency

Inventor： Hiroshi Kageyama ,  Kazuki Nakanishi ,  Yoji Kobayashi ,  Atsushi Kitada ,  George Hasegawa

IPC: C01G23/04 ,  B82Y30/00 ,  C01B21/076 ,  C04B35/58 ,  C01B21/082 ,  C04B35/46 ,  C04B41/00 ,  C04B41/80 ,  C04B38/00 ,  C25B11/04 ,  H01M4/48 ,  C04B111/00

CPC classification number: C01G23/043 ,  B82Y30/00 ,  C01B21/076 ,  C01B21/0761 ,  C01B21/0821 ,  C01P2002/72 ,  C01P2004/03 ,  C01P2004/61 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2006/40 ,  C04B35/46 ,  C04B35/58014 ,  C04B38/0032 ,  C04B41/0072 ,  C04B41/009 ,  C04B41/80 ,  C04B2111/0081 ,  C04B2111/00818 ,  C04B2235/3232 ,  C04B2235/3886 ,  C04B2235/404 ,  C04B2235/422 ,  C04B2235/48 ,  C04B2235/616 ,  C04B2235/6587 ,  C04B2235/664 ,  C04B2235/79 ,  C04B2235/81 ,  C25B11/04 ,  H01M4/48 ,  C04B38/00

Abstract: Provided are a macroporous titanium compound monolith and a production method thereof, the macroporous titanium compound monolith having a framework that is composed of a titanium compound other than titanium dioxide, having controlled macropores, and having electron conductivity, the titanium compound being oxygen-deficient titanium oxide, titanium oxynitride, or titanium nitride. Provided is a method including: placing a macroporous titanium dioxide monolith and a metal having titanium-reducing ability in a container, the macroporous titanium dioxide monolith having a co-continuous structure of a macropore and a framework that is composed of titanium dioxide; creating a vacuum atmosphere or an inert gas atmosphere within the container; and heating the monolith and the metal to cause gas-phase reduction that removes oxygen atom from the titanium dioxide composing the monolith by the metal acting as an oxygen getter, thereby obtaining a macroporous oxygen-deficient titanium oxide monolith having a co-continuous structure of the macropore and a framework that is composed of oxygen-deficient titanium oxide, the macroporous oxygen-deficient titanium oxide monolith having electron conductivity derived from the oxygen-deficient titanium oxide.

公开(公告)号：US09899993B2

公开(公告)日：2018-02-20

申请号：US14913309

申请日：2014-07-29

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Hidetoshi Onodera ,  Islam A. K. M Mahfuzul

IPC: H03K5/134 ,  G01R31/28 ,  H03K5/00

CPC classification number: H03K5/134 ,  G01R31/2882 ,  H03K2005/00019

Abstract: A delay circuit contains a first inversion circuit including a pull-up circuit and a pull-down circuit, and a second inversion circuit including a pull-up circuit and a pull-down circuit. The delay circuit further contains a first pass transistor connected in series to the pull-up circuit in the first inversion circuit between a power supply potential and an output node, a second pass transistor connected in series to the pull-down circuit in the first inversion circuit between a ground potential and the output node, a third pass transistor connected in series between the input node and the pull-up circuit in the second inversion circuit, and a fourth pass transistor connected in series between the input node and the pull-down circuit in the second inversion circuit. A delay characteristic of the delay circuit is changed by a combination of control signals applied to gates of the pass transistors.

公开(公告)号：US20180044683A1

公开(公告)日：2018-02-15

申请号：US15552440

申请日：2016-02-19

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Kohsuke HONDA ,  Haruyuki ATOMI

IPC: C12N15/52 ,  C12N9/02 ,  C07H21/04 ,  C12N15/70 ,  C12N1/20 ,  C12N5/10

CPC classification number: C12N15/52 ,  C07H21/04 ,  C12N1/20 ,  C12N5/10 ,  C12N9/0036 ,  C12N15/09 ,  C12N15/70 ,  C12P19/32

Abstract: The present invention provides a method for synthesizing NAD+ or NADH in an enzyme reaction system requiring NAD+ or NADH so as to supplement NAD+ lost due to thermal decomposition in the enzyme reaction system, and a transformant set for coenzyme production used in the method. That is, the present invention relates to a method for producing a coenzyme including performing synthesis of NAD+ or NADH in an enzyme reaction system requiring NAD+ or NADH by adding one or more thermostable enzymes required for a reaction for synthesizing NAD+ from nicotinamide, to the enzyme reaction system, and a transformant set for coenzyme production including one or more transformants into which one or more genes encoding thermostable enzymes required for a reaction for synthesizing NAD+ or NADH from nicotinamide are introduced by using a non-thermostable microorganism as a host.

公开(公告)号：US09876067B2

公开(公告)日：2018-01-23

申请号：US14778578

申请日：2014-03-12

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Tatsuya Shimoda ,  Eisuke Tokumitsu ,  Masatoshi Onoue ,  Takaaki Miyasako

IPC: H01L21/02 ,  H01L49/02 ,  H01L29/51

CPC classification number: H01L28/40 ,  H01L21/02194 ,  H01L21/022 ,  H01L21/02205 ,  H01L21/02269 ,  H01L28/56 ,  H01L28/60 ,  H01L28/87 ,  H01L28/91 ,  H01L29/513

Abstract: The invention provides a dielectric layer having high relative permittivity with low leakage current and excellent flatness. A dielectric layer 30a according to the invention is made of multilayer oxide including a first oxide layer 31 made of oxide consisting of bismuth (Bi) and niobium (Nb) or oxide consisting of bismuth (Bi), zinc (Zn), and niobium (Nb) (possibly including inevitable impurities) and a second oxide layer 32 made of oxide of one type (possibly including inevitable impurities) selected from the group of oxide consisting of lanthanum (La) and tantalum (Ta), oxide consisting of lanthanum (La) and zirconium (Zr), and oxide consisting of strontium (Sr) and tantalum (Ta).

公开(公告)号：US09873109B2

公开(公告)日：2018-01-23

申请号：US14595130

申请日：2015-01-12

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY ,  CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Yoshihiro Yamazaki ,  Sossina M. Haile ,  Chih-Kai Yang

IPC: B01J23/889 ,  B01J23/34 ,  B01J37/08 ,  B01J23/00 ,  B01J23/83 ,  B01J35/00 ,  C01B3/06 ,  C01B13/02 ,  C07C29/159 ,  B01J23/26 ,  C01B3/04 ,  C07C1/20

CPC classification number: B01J23/8892 ,  B01J23/002 ,  B01J23/26 ,  B01J23/34 ,  B01J23/83 ,  B01J35/002 ,  B01J37/08 ,  B01J2523/00 ,  C01B3/045 ,  C01B3/063 ,  C01B13/024 ,  C01B2203/0277 ,  C01B2203/0805 ,  C01B2203/1088 ,  C07C1/20 ,  C07C29/159 ,  C07C2523/26 ,  C07C2523/34 ,  C07C2523/889 ,  Y02E60/364 ,  Y02P20/129 ,  Y02P20/134 ,  Y02P20/52 ,  B01J2523/24 ,  B01J2523/3706 ,  B01J2523/72 ,  B01J2523/842 ,  B01J2523/47 ,  B01J2523/847 ,  B01J2523/22 ,  C07C31/04

Abstract: To provide a catalyst, which is formed from a perovskite oxide, for thermochemical fuel production, and a method of producing fuel using thermochemical fuel production that is capable of allowing a fuel to be produced in a thermochemical manner. Provided is a catalyst for thermochemical fuel production, which is used for producing the fuel from thermal energy by using a two-step thermochemical cycle of a first temperature and a second temperature that is equal to or lower than the first temperature, wherein the catalyst is formed from a perovskite oxide having a compositional formula of AXO3±δ (provided that, 0≦δ≦1). Here, A represents one or more of a rare-earth element (excluding Ce), an alkaline earth metal element, and an alkali metal element, X represents one or more of a transition metal element and a metalloid element, and O represents oxygen.

公开(公告)号：US09873108B2

公开(公告)日：2018-01-23

申请号：US14765283

申请日：2013-12-02

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Tetsuro Majima ,  Takashi Tachikawa ,  Zhenfeng Bian

IPC: B01J23/80 ,  C01G23/053 ,  C01G53/00 ,  C01G53/04 ,  C01G3/02 ,  C01G9/02 ,  C01B13/18 ,  C01G1/02 ,  B01J21/06 ,  B01J23/06 ,  B01J23/72 ,  B01J23/755 ,  B01J35/00 ,  B01J35/02 ,  B01J37/12 ,  C01G9/00 ,  C30B19/08 ,  C30B29/16 ,  C30B29/22 ,  H01B1/08 ,  B01J23/10 ,  B01J23/745 ,  B01J23/75 ,  B01J35/10 ,  B01J37/02

CPC classification number: B01J23/80 ,  B01J21/063 ,  B01J21/066 ,  B01J23/06 ,  B01J23/10 ,  B01J23/72 ,  B01J23/745 ,  B01J23/75 ,  B01J23/755 ,  B01J35/002 ,  B01J35/004 ,  B01J35/006 ,  B01J35/02 ,  B01J35/023 ,  B01J35/1009 ,  B01J35/1014 ,  B01J35/1061 ,  B01J37/0203 ,  B01J37/12 ,  C01B13/18 ,  C01G1/02 ,  C01G3/02 ,  C01G9/006 ,  C01G9/02 ,  C01G23/053 ,  C01G53/00 ,  C01G53/04 ,  C01G53/40 ,  C01P2002/72 ,  C01P2002/84 ,  C01P2004/04 ,  C01P2004/62 ,  C01P2004/64 ,  C01P2006/12 ,  C30B19/08 ,  C30B29/16 ,  C30B29/225 ,  H01B1/08

Abstract: Various metal oxide mesocrystals can be synthesized in a simple manner by a method for producing a metal oxide mesocrystal, the method comprising the step of annealing an aqueous precursor solution comprising one or more metal oxide precursors, an ammonium salt, a surfactant, and water at 300 to 600° C. Composite mesocrystals consisting of a plurality of metal oxides or an alloy oxide can also be provided.

公开(公告)号：US20180015036A1

公开(公告)日：2018-01-18

申请号：US15660746

申请日：2017-07-26

Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY

Inventor： Kazunori Kataoka ,  Akihiro Kishimura ,  Yasutaka Anraku ,  Kanjiro Miyata ,  Sayan Chuanoi ,  Tomoya Suma ,  Makoto Oba

IPC: A61K9/00 ,  A61K9/127 ,  B01J13/02 ,  B01J13/14

CPC classification number: A61K9/0087 ,  A61K9/1273 ,  B01J13/02 ,  B01J13/14

Abstract: Provided is a method for easily and efficiently producing encapsulated substance vesicles wherein a substance is encapsulated in the cavity of vesicles obtained by polymer self-assembly. Empty vesicles that have membranes comprising a first polymer that is a block copolymer with uncharged hydrophilic segments and a first kind of charged segments and a second polymer with a second kind of charged segments that carry a charge that is the opposite of said first kind of charged segments as well as spaces that are enclosed by said membranes are mixed in an aqueous medium with the substance that is to be encapsulated in the spaces.