REDUCING MEASUREMENT VARIATION TO OPTICAL MEASURING OF SAMPLE MATERIAL

    公开(公告)号:US20180038801A1

    公开(公告)日:2018-02-08

    申请号:US15787747

    申请日:2017-10-19

    Applicant: WALLAC OY

    Inventor: Ville LAITALA

    Abstract: A measurement device includes mechanical support elements (101-104) for supporting a sample well, other mechanical support elements (105-109) for supporting a measurement head (112) suitable for optical measurements, and a control system (111) configured to control the measurement head to carry out at least two optical measurements from at least two different measurement locations inside the sample well, where each measurement location is a center point of a capture range from which radiation is captured in the respective optical measurement. The final measurement result is formed from the results of the at least two optical measurements in accordance with a pre-determined rule. The use of the at least two optical measurements from different measurement locations reduces measurement variation in situations where the sample well (153) contains a piece (158) of sample carrier.

    Fluorescence-based scanning imaging device
    77.
    发明授权
    Fluorescence-based scanning imaging device 有权
    基于荧光的扫描成像装置

    公开(公告)号:US07911670B2

    公开(公告)日:2011-03-22

    申请号:US12092767

    申请日:2006-11-07

    Abstract: A device for analysing a specimen by fluorescence includes a confocal microscope, illumination means capable of emitting a light beam that converges, by means of an objective, on a focal spot, means for successively positioning the focal spot at various points on the specimen during analysis. The confocal microscope includes an objective mounted on a movable rapid-scan carriage driven in a reciprocating linear movement along a traverse direction by a rotating motor by means of a device of the connecting rod type. The specimen is placed on a movable support driven in a longitudinal movement and is able to move along the axis of the objective of the microscope in order to position the specimen relative to the focal spot. The excitation light spectrum is spread over the surface of the specimen in such a way that the excitation light reflected by the specimen and corresponding to the wavelengths close to fluorescence converge on points that are sufficiently distant from a diaphragm positioned in front of a device for measuring the fluorescence.

    Abstract translation: 用于通过荧光分析样品的装置包括共聚焦显微镜,能够发射通过物镜会聚在焦点上的光束的照明装置,用于在分析期间将焦斑连续地定位在样品上的各个点处的装置 。 共焦显微镜包括安装在可移动快速扫描托架上的物镜,该移动快速扫描托架借助于连杆型的装置沿着横动方向由旋转马达沿往复线性运动驱动。 样本被放置在以纵向运动驱动的可移动支撑上,并且能够沿着显微镜的物镜的轴线移动,以便使样本相对于焦点定位。 激发光谱以试样的反射并对应于接近荧光的波长的激发光在测量装置前方的光阑上充分远离的位置上分散在试样的表面上, 荧光。

    Reduction of wire numbers in a paper scanner power track
    78.
    发明申请
    Reduction of wire numbers in a paper scanner power track 有权
    减少纸张扫描仪电源轨道中的电线编号

    公开(公告)号:US20090099682A1

    公开(公告)日:2009-04-16

    申请号:US11973942

    申请日:2007-10-10

    CPC classification number: G01N33/346 G01N21/86 G01N2021/8663 G01N2201/101

    Abstract: The performance of scanning systems can be significantly enhanced by replacing the traditional power track with preferably just two wires or transmission channels for effecting communication between (i) the sensors on the mobile carriage of the scanning system and (ii) the controls, power sources, and related devices that are typically located in a compartment or module which is a significant distance away. This can be implemented by employing selected multiplexer and complementary de-multiplexer combinations in the scanner head and in the module. This technique reduces EMI noise, power loss, drag on the moving scanner heads carrying the sensors, and cost of construction.

    Abstract translation: 通过用优选仅两条电线或传输通道代替传统电力轨道来实现扫描系统的性能可以显着提高,以实现(i)扫描系统的移动支架上的传感器与(ii)控制电源, 以及通常位于距离很远的隔间或模块中的相关设备。 这可以通过在扫描仪头部和模块中采用选定的多路复用器和互补解复用器组合来实现。 这种技术降低了EMI噪声,功率损耗,拖动运动的扫描仪头上传感器,以及施工成本。

    Coloration measuring device
    79.
    发明授权
    Coloration measuring device 有权
    着色测量装置

    公开(公告)号:US07408644B2

    公开(公告)日:2008-08-05

    申请号:US10535259

    申请日:2003-10-30

    Abstract: A scanning mechanism 6 moves an optical head 5 relative to a mount plate 2 in a scan direction, and light emitting diodes 3A, 3B mounted on the optical head 5 emit their respective beams of measurement light along the scan direction and onto two color regions TP3, TP3, respectively, of an immunochromatographic test strip mounted on the mount plate 2. Photodiodes 4A, 4B mounted on the optical head 5 receive respective beams of reflected light from the two color regions TP3, TP3 perpendicularly to colored lines on the immunochromatographic test strip, thereby implementing simultaneous measurement of color intensities of the colored lines formed in the two color regions TP3, TP3 of the immunochromatographic test strip.

    Abstract translation: 扫描机构6在扫描方向上相对于安装板2移动光学头5,并且安装在光学头5上的发光二极管3A,3B沿着扫描方向发射它们各自的测量光束,并且发射到两个颜色 分别安装在安装板2上的免疫层析试片的区域TP 3,TP 3。 安装在光学头5上的光电二极管4A,4B接收来自两个颜色区域TP 3,TP 3的反射光的垂直于免疫色谱测试条上的着色线的反射光束,从而实现形成的着色线的色强度的同时测量 在两个颜色区域TP 3,TP 3的免疫层析试片。

    Scanning optical system
    80.
    发明授权
    Scanning optical system 有权
    扫描光学系统

    公开(公告)号:US07042647B2

    公开(公告)日:2006-05-09

    申请号:US10677587

    申请日:2003-10-02

    Applicant: William K. Lo

    Inventor: William K. Lo

    Abstract: A scanned optical system for use in optical probing applications provides a large Field of View (FOV) for objective lenses having high Numerical Aperture (NA), such as Solid Immersion Lenses (SIL's). This enables high resolution imaging of semiconductor devices for such applications as laser probing, TIVA/LIVA, OBIRCH, and photon emission timing analysis. A hybrid scanning optics configuration is disclosed to provide high resolution imaging over a small area along with low resolution imaging over a large area.

    Abstract translation: 用于光学探测应用的扫描光学系统为具有高数值孔径(NA)的物镜(例如固体浸没透镜(SIL))提供了大视场(FOV)。 这样可实现用于激光探测,TIVA / LIVA,OBIRCH和光子发射时序分析等半导体器件的高分辨率成像。 公开了一种混合扫描光学配置,以在大面积上提供在小区域上的高分辨率成像以及低分辨率成像。

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