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1.发明申请公开(公告)号：US20180344393A1
公开(公告)日：2018-12-06
申请号：US16000770
申请日：2018-06-05
Inventor： Sarah M. Gruba , James P. Rohl , Samuel J. Asirvatham , Suraj Kapa , Chance M. Witt , Deepak Padmanabhan , Christopher V. DeSimone
CPC classification number: A61B18/1492 , A61B2018/00232 , A61B2018/00238 , A61B2018/00255 , A61B2018/00261 , A61B2018/00375 , A61B2018/00488 , A61B2018/00529 , A61B2018/00577 , A61B2018/00613 , A61B2018/00791 , A61B2018/00839 , A61B2018/00875 , A61B2018/1472 , A61N1/056
Abstract: Embodiments of the present disclosure relate to treating diseased tissue with ablation therapy. In an embodiment, an apparatus comprises a catheter having an elongate body extending between a proximal end and a distal end. The apparatus further includes a balloon structure arranged proximal to the distal end of the catheter, wherein the balloon structure has a first portion with a first permeability and a second portion with a second permeability such that the first permeability is different than the second permeability. In addition, the apparatus includes a first electrode arranged on or within the balloon structure and configured to: transmit current through the first portion, receive current transmitted through the first portion or both.
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2.发明授权公开(公告)号：US09180289B2
公开(公告)日：2015-11-10
申请号：US13963559
申请日：2013-08-09
Applicant: Cardiac Pacemakers, Inc.
Inventor： Mary M. Byron , Diana Ma , James P. Rohl , Hood Chatham , Frank De Francesco
CPC classification number: B05D5/00 , A61L27/18 , A61L27/306 , A61L27/50 , A61L31/06 , A61L31/08 , A61L31/10 , A61L31/14 , A61L2400/02 , A61L2400/10 , A61L2400/18 , A61L2420/02 , A61N1/05 , B05D1/62 , C23C16/045 , C23C16/401 , C23C16/505 , C23C16/52 , C08L83/04
Abstract: An implantable or insertable medical device can include a silicone substrate and a plasma-enhanced chemical vapor deposition coating on the silicone substrate. The coating may include a silicon-containing compound. A method of forming the coating is also provided.
Abstract translation: 可植入或可插入的医疗装置可以包括硅树脂衬底和硅树脂衬底上的等离子体增强化学气相沉积涂层。 涂层可以包括含硅化合物。 还提供了形成涂层的方法。
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3.发明申请公开(公告)号：US20180264248A1
公开(公告)日：2018-09-20
申请号：US15972611
申请日：2018-05-07
Applicant: Cardiac Pacemakers, Inc.
Inventor： Adegbola O. Adenusi , James P. Rohl , David R. Wulfman , Joseph T. Delaney, JR. , Adeniyi Aremu
IPC: A61M39/08 , B32B1/08 , A61L29/04 , D01D5/098 , D01D5/00 , B32B27/12 , B32B27/08 , B32B5/02 , A61N1/05 , A61L31/14 , A61L31/10 , A61L31/06 , A61L31/04 , A61L29/14 , A61L29/08 , A61L29/06 , A61M39/00 , C08L71/02 , C08L39/06 , C08L75/04 , C08L83/04
CPC classification number: A61M39/08 , A61L29/041 , A61L29/06 , A61L29/085 , A61L29/145 , A61L29/146 , A61L31/048 , A61L31/06 , A61L31/10 , A61L31/145 , A61L31/146 , A61M39/00 , A61N1/0541 , A61N1/056 , B32B1/08 , B32B5/02 , B32B5/022 , B32B27/08 , B32B27/12 , B32B2262/0238 , B32B2535/00 , D01D5/0023 , D01D5/0076 , D01D5/0084 , D01D5/0985 , Y10T428/1372 , C08L71/02 , C08L39/06 , C08L75/04 , C08L83/04
Abstract: A medical device made of a hybrid polymeric structure includes a tubular body including a first layer and a second layer. The first layer includes a fibrous matrix comprising a plurality of randomly oriented nanofibers made at least in part of a first polymeric material and pores formed between at least a portion of the nanofibers. The second layer is made at least in part of a second polymeric material. At least a portion of the second layer is disposed about and between the plurality of nanofibers such that at least a portion of the second polymeric material is embedded into at least a portion of the pores of the fibrous matrix.
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4.发明申请MEDICAL DEVICE HYBRID POLYMERIC STRUCTURES AND COATINGS WITH IMPROVED LUBRICITY AND DURABILITY 有权具有改善润滑性和耐久性的医疗装置混合聚合物结构和涂层公开(公告)号：US20150202423A1
公开(公告)日：2015-07-23
申请号：US14600611
申请日：2015-01-20
Applicant: Cardiac Pacemakers, Inc.
Inventor： Adegbola O. Adenusi , James P. Rohl , David R. Wulfman , Joseph T. Delaney, JR. , Adeniyi Aremu
CPC classification number: A61M39/08 , A61L29/041 , A61L29/06 , A61L29/085 , A61L29/145 , A61L29/146 , A61L31/048 , A61L31/06 , A61L31/10 , A61L31/145 , A61L31/146 , A61M39/00 , A61N1/0541 , A61N1/056 , B32B1/08 , B32B5/02 , B32B5/022 , B32B27/08 , B32B27/12 , B32B2262/0238 , B32B2535/00 , D01D5/0023 , D01D5/0076 , D01D5/0084 , D01D5/0985 , Y10T428/1372 , C08L71/02 , C08L39/06 , C08L75/04 , C08L83/04
Abstract: A method for making a tubular medical device having a hybrid polymeric structure includes forming a first layer comprising a non-woven fibrous matrix made of a first polymeric material and forming a second layer comprising a second polymeric material about the first layer such that at least a portion of the second polymeric material of the second layer embeds into at least a portion of the first polymeric material of the first layer.
Abstract translation: 制备具有复合聚合物结构的管状医疗装置的方法包括形成包含由第一聚合物材料制成的非织造纤维基质的第一层，并形成围绕第一层的第二聚合物材料的第二层，使得至少一 第二层的第二聚合物材料的部分嵌入第一层的第一聚合物材料的至少一部分。
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公开(公告)号：US11426233B2
公开(公告)日：2022-08-30
申请号：US16000770
申请日：2018-06-05
Inventor： Sarah M. Gruba , James P. Rohl , Samuel J. Asirvatham , Suraj Kapa , Chance M. Witt , Deepak Padmanabhan , Christopher V. DeSimone
Abstract: Embodiments of the present disclosure relate to treating diseased tissue with ablation therapy. In an embodiment, an apparatus comprises a catheter having an elongate body extending between a proximal end and a distal end. The apparatus further includes a balloon structure arranged proximal to the distal end of the catheter, wherein the balloon structure has a first portion with a first permeability and a second portion with a second permeability such that the first permeability is different than the second permeability. In addition, the apparatus includes a first electrode arranged on or within the balloon structure and configured to: transmit current through the first portion, receive current transmitted through the first portion or both.
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Patent Agency Ranking
6.发明申请公开(公告)号：US20140067028A1
公开(公告)日：2014-03-06
申请号：US13963559
申请日：2013-08-09
Applicant: Cardiac Pacemakers, Inc.
Inventor： Mary M. Byron , Diana Ma , James P. Rohl , Hood Chatham , Frank De Francesco
CPC classification number: B05D5/00 , A61L27/18 , A61L27/306 , A61L27/50 , A61L31/06 , A61L31/08 , A61L31/10 , A61L31/14 , A61L2400/02 , A61L2400/10 , A61L2400/18 , A61L2420/02 , A61N1/05 , B05D1/62 , C23C16/045 , C23C16/401 , C23C16/505 , C23C16/52 , C08L83/04
Abstract: An implantable or insertable medical device can include a silicone substrate and a plasma-enhanced chemical vapor deposition coating on the silicone substrate. The coating may include a silicon-containing compound. A method of forming the coating is also provided.
Abstract translation: 可植入或可插入的医疗装置可以包括硅树脂衬底和硅树脂衬底上的等离子体增强化学气相沉积涂层。 涂层可以包括含硅化合物。 还提供了形成涂层的方法。
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7.发明申请公开(公告)号：US20190060632A1
公开(公告)日：2019-02-28
申请号：US16107046
申请日：2018-08-21
Inventor： Samuel J. Asirvatham , Suraj Kapa , Sarah M. Gruba , Douglas D. Pagoria , James P. Rohl , Chance M. Witt , Ammar M. Killu , Niyada Naksuk
IPC: A61N1/04 , A61N1/32 , A61B18/14 , A61B5/0472
Abstract: The present disclosure relates generally to electroporation systems and utilizing algorithms for electroporation pulse delivery including a patient's EKG/EGM monitoring. In some embodiments, an electroporation delivery system may include an electrocardiogram operatively connected to a processing device and a memory. One or more sensors may be operatively connected to the electrocardiogram for measuring electrical activity QRS complex of a patient's heart. One or more electrodes for treatment may be disposed in, at, or near the patient's heart, the one or more electrodes operatively connected to a pulse delivery mechanism. The electroporation delivery system may be configured to determine whether an electroporation pulse is deliverable to a patient based on the electrocardiogram.
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公开(公告)号：US09987478B2
公开(公告)日：2018-06-05
申请号：US14600611
申请日：2015-01-20
Applicant: Cardiac Pacemakers, Inc.
Inventor： Adegbola O. Adenusi , James P. Rohl , David R. Wulfman , Joseph T. Delaney, Jr. , Adeniyi Aremu
IPC: B29C71/02 , A61M39/08 , A61M39/00 , B32B1/08 , B32B5/02 , B32B27/08 , B32B27/12 , D01D5/00 , D01D5/098 , A61L29/04 , A61L29/06 , A61L29/08 , A61L29/14 , A61L31/04 , A61L31/06 , A61L31/10 , A61L31/14 , A61N1/05
CPC classification number: A61M39/08 , A61L29/041 , A61L29/06 , A61L29/085 , A61L29/145 , A61L29/146 , A61L31/048 , A61L31/06 , A61L31/10 , A61L31/145 , A61L31/146 , A61M39/00 , A61N1/0541 , A61N1/056 , B32B1/08 , B32B5/02 , B32B5/022 , B32B27/08 , B32B27/12 , B32B2262/0238 , B32B2535/00 , D01D5/0023 , D01D5/0076 , D01D5/0084 , D01D5/0985 , Y10T428/1372 , C08L71/02 , C08L39/06 , C08L75/04 , C08L83/04
Abstract: A method for making a tubular medical device having a hybrid polymeric structure includes forming a first layer comprising a non-woven fibrous matrix made of a first polymeric material and forming a second layer comprising a second polymeric material about the first layer such that at least a portion of the second polymeric material of the second layer embeds into at least a portion of the first polymeric material of the first layer.
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公开(公告)号：US20220296881A1
公开(公告)日：2022-09-22
申请号：US17833269
申请日：2022-06-06
Inventor： Samuel J. Asirvatham , Suraj Kapa , Sarah M. Gruba , Douglas D. Pagoria , James P. Rohl , Chance M. Witt , Ammar M. Killu , Niyada Naksuk
Abstract: The present disclosure relates generally to electroporation systems and utilizing algorithms for electroporation pulse delivery including a patient's EKG/EGM monitoring. In some embodiments, an electroporation delivery system may include an electrocardiogram operatively connected to a processing device and a memory. One or more sensors may be operatively connected to the electrocardiogram for measuring electrical activity QRS complex of a patient's heart. One or more electrodes for treatment may be disposed in, at, or near the patient's heart, the one or more electrodes operatively connected to a pulse delivery mechanism. The electroporation delivery system may be configured to determine whether an electroporation pulse is deliverable to a patient based on the electrocardiogram.
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公开(公告)号：US09737905B2
公开(公告)日：2017-08-22
申请号：US14879433
申请日：2015-10-09
Applicant: Cardiac Pacemakers, Inc.
Inventor： Mary M. Byron , Diana K. Ma , James P. Rohl , Hood Chatham , Frank De Francesco
IPC: C23C16/52 , C23C16/40 , B05D5/00 , A61L27/18 , A61L27/30 , A61L27/50 , A61L31/06 , A61L31/14 , A61L31/08 , A61N1/05 , A61L31/10 , B05D1/00 , C23C16/04 , C23C16/505
CPC classification number: B05D5/00 , A61L27/18 , A61L27/306 , A61L27/50 , A61L31/06 , A61L31/08 , A61L31/10 , A61L31/14 , A61L2400/02 , A61L2400/10 , A61L2400/18 , A61L2420/02 , A61N1/05 , B05D1/62 , C23C16/045 , C23C16/401 , C23C16/505 , C23C16/52 , C08L83/04
Abstract: An implantable or insertable medical device can include a silicone substrate and a plasma-enhanced chemical vapor deposition coating on the silicone substrate. The coating may include a silicon-containing compound. A method of forming the coating is also provided.
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