公开(公告)号：US20200058478A1

公开(公告)日：2020-02-20

申请号：US16662881

申请日：2019-10-24

Applicant: Micromass UK Limited

Inventor： Tamas KARANCSI ,  Lajos GODORHAZY ,  Daniel SZALAY ,  Zoltan TAKATS ,  Julia BALOG ,  Steven Derek PRINGLE ,  Daniel SIMON

IPC: H01J49/04 ,  H01J49/26 ,  H01J49/24 ,  H01J49/16 ,  H01J49/14 ,  H01J49/10 ,  H01J49/06 ,  H01J49/02 ,  H01J49/00 ,  G01N33/92 ,  G01N33/68 ,  G01N33/487 ,  G01N30/72 ,  G01N27/62 ,  G01N1/22 ,  C12Q1/24 ,  C12Q1/18 ,  C12Q1/04 ,  C12Q1/02 ,  A61F13/38 ,  A61B18/18 ,  A61B18/14 ,  A61B18/04 ,  A61B17/00 ,  A61B10/00 ,  A61B8/13 ,  A61B6/03 ,  A61B5/055 ,  A61B5/05 ,  A61B5/01 ,  A61B5/00 ,  A61B1/273 ,  A61B1/04 ,  A61B90/13 ,  G01N9/00 ,  G01N3/00 ,  A61B18/20 ,  A61B18/00 ,  A61B17/32 ,  A61B10/02

Abstract: An apparatus for mass spectrometry and/or ion mobility spectrometry is disclosed comprising a first device arranged and adapted to generate aerosol, smoke or vapour from a target and one or more second devices arranged and adapted to aspirate aerosol, smoke, vapour and/or liquid to or towards an analyser. A liquid trap or separator is provided to capture and/or discard liquid aspirated by the one or more second devices.

公开(公告)号：US20180057852A1

公开(公告)日：2018-03-01

申请号：US15556022

申请日：2016-03-07

Applicant: Micromass UK Limited

Inventor： Zoltan TAKATS ,  Frances BOLT ,  Tamas KARANCSI ,  Emrys JONES ,  Keith RICHARDSON ,  Lajos GODORHAZY ,  Daniel SZALAY ,  Julia BALOG ,  Steven Derek PRINGLE ,  Daniel SIMON

IPC: C12Q1/04 ,  G01N33/92 ,  G01N1/22 ,  C12Q1/18 ,  C12Q1/02 ,  C12Q1/24 ,  G01N27/62 ,  H01J49/00 ,  H01J49/16

CPC classification number: H01J49/049 ,  A61B1/00013 ,  A61B1/041 ,  A61B1/2736 ,  A61B1/31 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/015 ,  A61B5/0507 ,  A61B5/055 ,  A61B5/14542 ,  A61B6/032 ,  A61B6/037 ,  A61B8/13 ,  A61B10/00 ,  A61B10/0041 ,  A61B10/0233 ,  A61B10/0283 ,  A61B17/00 ,  A61B17/320068 ,  A61B18/00 ,  A61B18/04 ,  A61B18/042 ,  A61B18/14 ,  A61B18/1445 ,  A61B18/1815 ,  A61B18/20 ,  A61B90/13 ,  A61B2010/0083 ,  A61B2017/320069 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00994 ,  A61B2218/002 ,  A61B2218/008 ,  A61F13/38 ,  C12Q1/025 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N1/2202 ,  G01N3/00 ,  G01N9/00 ,  G01N27/622 ,  G01N27/624 ,  G01N30/724 ,  G01N33/487 ,  G01N33/48735 ,  G01N33/6848 ,  G01N33/6851 ,  G01N33/92 ,  G01N2001/2223 ,  G01N2333/195 ,  G01N2405/00 ,  G01N2405/04 ,  G01N2405/08 ,  G01N2570/00 ,  G01N2800/26 ,  G06F19/324 ,  G06F19/3481 ,  G16B20/00 ,  G16H10/40 ,  G16H15/00 ,  G16H50/20 ,  H01J49/0004 ,  H01J49/0027 ,  H01J49/0031 ,  H01J49/0036 ,  H01J49/025 ,  H01J49/0404 ,  H01J49/0409 ,  H01J49/0422 ,  H01J49/044 ,  H01J49/0445 ,  H01J49/0459 ,  H01J49/0463 ,  H01J49/0468 ,  H01J49/061 ,  H01J49/068 ,  H01J49/10 ,  H01J49/14 ,  H01J49/16 ,  H01J49/164 ,  H01J49/24 ,  H01J49/26

Abstract: A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed. The method comprises: using a first device to generate smoke, aerosol or vapour from a target comprising or consisting of a microbial population; mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and analysing said spectrometric data in order to analyse said microbial population.

公开(公告)号：US20180047554A1

公开(公告)日：2018-02-15

申请号：US15555783

申请日：2016-03-07

Applicant: Micromass UK Limited

Inventor： Zoltan TAKATS ,  Emrys JONES ,  James Ian LANGRIDGE ,  Michael Raymond MORRIS ,  Tamas KARANCSI ,  Steven Derek PRINGLE ,  Julia BALOG ,  Daniel SIMON ,  Lajos GODORHAZY ,  Daniel SZALAY ,  Keith RICHARDSON

IPC: H01J49/04 ,  G01N27/62 ,  H01J49/00 ,  H01J49/16 ,  A61B18/20 ,  A61F13/38 ,  A61B10/02 ,  A61B18/04 ,  A61B18/18 ,  G01N33/487 ,  A61B10/00

CPC classification number: G01N1/2202 ,  A61B1/00013 ,  A61B1/041 ,  A61B1/2736 ,  A61B1/31 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/015 ,  A61B5/0507 ,  A61B5/055 ,  A61B5/14542 ,  A61B6/032 ,  A61B6/037 ,  A61B8/13 ,  A61B10/00 ,  A61B10/0041 ,  A61B10/0233 ,  A61B10/0283 ,  A61B17/00 ,  A61B17/320068 ,  A61B18/00 ,  A61B18/04 ,  A61B18/042 ,  A61B18/14 ,  A61B18/1445 ,  A61B18/1815 ,  A61B18/20 ,  A61B90/13 ,  A61B2010/0083 ,  A61B2017/320069 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00994 ,  A61B2218/002 ,  A61B2218/008 ,  A61F13/38 ,  C12Q1/025 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N3/00 ,  G01N9/00 ,  G01N27/622 ,  G01N27/624 ,  G01N30/724 ,  G01N33/487 ,  G01N33/48735 ,  G01N33/6848 ,  G01N33/6851 ,  G01N33/92 ,  G01N2001/2223 ,  G01N2333/195 ,  G01N2405/00 ,  G01N2405/04 ,  G01N2405/08 ,  G01N2570/00 ,  G01N2800/26 ,  G06F19/18 ,  G06F19/324 ,  G06F19/3481 ,  G16H50/20 ,  H01J49/0004 ,  H01J49/0027 ,  H01J49/0031 ,  H01J49/0036 ,  H01J49/025 ,  H01J49/0404 ,  H01J49/0409 ,  H01J49/0422 ,  H01J49/0445 ,  H01J49/0459 ,  H01J49/0463 ,  H01J49/0468 ,  H01J49/049 ,  H01J49/061 ,  H01J49/068 ,  H01J49/10 ,  H01J49/14 ,  H01J49/16 ,  H01J49/164 ,  H01J49/24 ,  H01J49/26

Abstract: A method is disclosed comprising providing a biological sample on a swab, directing a spray of charged droplets onto a surface of the swab in order to generate a plurality of analyte ions, and analysing the analyte ions.

公开(公告)号：US20180238776A1

公开(公告)日：2018-08-23

申请号：US15554626

申请日：2016-03-07

Applicant: Micromass UK Limited

Inventor： Tamas KARANCSI ,  Lajos GODORHAZY ,  Daniel SZALAY ,  Zoltan TAKATS ,  Julia BALOG ,  Steven Derek PRINGLE ,  Daniel SIMON

IPC: G01N1/22 ,  A61B1/273 ,  A61B5/00 ,  A61B18/20 ,  A61B18/04 ,  A61B18/14 ,  G01N27/62 ,  H01J49/04 ,  H01J49/00

Abstract: An apparatus for mass spectrometry and/or ion mobility spectrometry is disclosed comprising a first device arranged and adapted to generate aerosol, smoke or vapour from a target and one or more second devices arranged and adapted to aspirate aerosol, smoke, vapour and/or liquid to or towards an analyser. A liquid trap or separator is provided to capture and/or discard liquid aspirated by the one or more second devices.

公开(公告)号：US20180103935A1

公开(公告)日：2018-04-19

申请号：US15555998

申请日：2016-03-07

Applicant: Micromass UK Limited

Inventor： Steven Derek PRINGLE ,  Tamas KARANCSI ,  Emrys JONES ,  Michael Raymond MORRIS ,  Julia BALOG ,  James Ian LANGRIDGE ,  Zoltan TAKATS ,  Frances BOLT ,  Lajos GODORHAZY ,  Daniel SZALAY ,  Daniel SIMON ,  Keith RICHARDSON

IPC: A61B10/00 ,  G01N33/68 ,  A61B18/14 ,  G01N33/92 ,  H01J49/00 ,  H01J49/04 ,  H01J49/16 ,  H01J49/06

CPC classification number: H01J49/049 ,  A61B1/00013 ,  A61B1/041 ,  A61B1/2736 ,  A61B1/31 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/015 ,  A61B5/0507 ,  A61B5/055 ,  A61B5/14542 ,  A61B6/032 ,  A61B6/037 ,  A61B8/13 ,  A61B10/00 ,  A61B10/0041 ,  A61B10/0233 ,  A61B10/0283 ,  A61B17/00 ,  A61B17/320068 ,  A61B18/00 ,  A61B18/04 ,  A61B18/042 ,  A61B18/14 ,  A61B18/1445 ,  A61B18/1815 ,  A61B18/20 ,  A61B90/13 ,  A61B2010/0083 ,  A61B2017/320069 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00994 ,  A61B2218/002 ,  A61B2218/008 ,  A61F13/38 ,  C12Q1/025 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N1/2202 ,  G01N3/00 ,  G01N9/00 ,  G01N27/622 ,  G01N27/624 ,  G01N30/724 ,  G01N33/487 ,  G01N33/48735 ,  G01N33/6848 ,  G01N33/6851 ,  G01N33/92 ,  G01N2001/2223 ,  G01N2333/195 ,  G01N2405/00 ,  G01N2405/04 ,  G01N2405/08 ,  G01N2570/00 ,  G01N2800/26 ,  G06F19/324 ,  G06F19/3481 ,  G16B20/00 ,  G16H10/40 ,  G16H15/00 ,  G16H50/20 ,  H01J49/0004 ,  H01J49/0027 ,  H01J49/0031 ,  H01J49/0036 ,  H01J49/025 ,  H01J49/0404 ,  H01J49/0409 ,  H01J49/0422 ,  H01J49/044 ,  H01J49/0445 ,  H01J49/0459 ,  H01J49/0463 ,  H01J49/0468 ,  H01J49/061 ,  H01J49/068 ,  H01J49/10 ,  H01J49/14 ,  H01J49/16 ,  H01J49/164 ,  H01J49/24 ,  H01J49/26

Abstract: A method of analysis using mass and/or ion mobility spectrometry or ion mobility spectrometry is disclosed comprising: using a first device to generate aerosol, smoke or vapour from one or more regions of a first target of biological material; and mass and/or ion mobility analysing and/or ion mobility analysing said aerosol, smoke, or vapour, or ions derived therefrom so as to obtain first spectrometric data. The method may use an ambient ionisation method.

公开(公告)号：US20180042583A1

公开(公告)日：2018-02-15

申请号：US15556064

申请日：2016-03-07

Applicant: Micromass UK Limited

Inventor： Steven Derek PRINGLE ,  Emrys JONES ,  Michael Raymond MORRIS ,  Julia BALOG ,  James Ian LANGRIDGE ,  Keith RICHARDSON ,  Daniel SIMON ,  Lajos GODORHAZY ,  Daniel SZALAY ,  Zoltan TAKATS

IPC: A61B10/00 ,  A61B18/04 ,  A61B18/18 ,  H01J49/02 ,  A61B90/13 ,  G01N27/62 ,  H01J49/04 ,  H01J49/00 ,  G01N33/92 ,  A61B18/20

CPC classification number: H01J49/049 ,  A61B1/00013 ,  A61B1/041 ,  A61B1/2736 ,  A61B1/31 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/015 ,  A61B5/0507 ,  A61B5/055 ,  A61B5/14542 ,  A61B6/032 ,  A61B6/037 ,  A61B8/13 ,  A61B10/00 ,  A61B10/0041 ,  A61B10/0233 ,  A61B10/0283 ,  A61B17/00 ,  A61B17/320068 ,  A61B18/00 ,  A61B18/04 ,  A61B18/042 ,  A61B18/14 ,  A61B18/1445 ,  A61B18/1815 ,  A61B18/20 ,  A61B90/13 ,  A61B2010/0083 ,  A61B2017/320069 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00994 ,  A61B2218/002 ,  A61B2218/008 ,  A61F13/38 ,  C12Q1/025 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N1/2202 ,  G01N3/00 ,  G01N9/00 ,  G01N27/622 ,  G01N27/624 ,  G01N30/724 ,  G01N33/487 ,  G01N33/48735 ,  G01N33/6848 ,  G01N33/6851 ,  G01N33/92 ,  G01N2001/2223 ,  G01N2333/195 ,  G01N2405/00 ,  G01N2405/04 ,  G01N2405/08 ,  G01N2570/00 ,  G01N2800/26 ,  G06F19/324 ,  G06F19/3481 ,  G16B20/00 ,  G16H10/40 ,  G16H15/00 ,  G16H50/20 ,  H01J49/0004 ,  H01J49/0027 ,  H01J49/0031 ,  H01J49/0036 ,  H01J49/025 ,  H01J49/0404 ,  H01J49/0409 ,  H01J49/0422 ,  H01J49/044 ,  H01J49/0445 ,  H01J49/0459 ,  H01J49/0463 ,  H01J49/0468 ,  H01J49/061 ,  H01J49/068 ,  H01J49/10 ,  H01J49/14 ,  H01J49/16 ,  H01J49/164 ,  H01J49/24 ,  H01J49/26

Abstract: A method is disclosed comprising obtaining or acquiring chemical or other non-mass spectrometric data from one or more regions of a target using a chemical sensor. The chemical or other non-mass spectrometric data may be used to determine one or more regions of interest of the target. An ambient ionisation ion source may then be used to generate aerosol, smoke or vapour from one or more regions of the target.

公开(公告)号：US20180053644A1

公开(公告)日：2018-02-22

申请号：US15555758

申请日：2016-03-07

Applicant: Micromass UK Limited

Inventor： Emrys JONES ,  Tamas KARANCSI ,  Steven Derek PRINGLE ,  Julia BALOG ,  Daniel SIMON ,  Lajos GODORHAZY ,  Daniel SZALAY ,  Zoltan TAKATS

IPC: H01J49/26 ,  G01N27/62 ,  G01N30/72 ,  H01J49/04 ,  H01J49/06 ,  H01J49/10 ,  H01J49/14 ,  H01J49/16 ,  H01J49/24

CPC classification number: H01J49/049 ,  A61B1/00013 ,  A61B1/041 ,  A61B1/2736 ,  A61B1/31 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/015 ,  A61B5/0507 ,  A61B5/055 ,  A61B5/14542 ,  A61B6/032 ,  A61B6/037 ,  A61B8/13 ,  A61B10/00 ,  A61B10/0041 ,  A61B10/0233 ,  A61B10/0283 ,  A61B17/00 ,  A61B17/320068 ,  A61B18/00 ,  A61B18/04 ,  A61B18/042 ,  A61B18/14 ,  A61B18/1445 ,  A61B18/1815 ,  A61B18/20 ,  A61B90/13 ,  A61B2010/0083 ,  A61B2017/320069 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00994 ,  A61B2218/002 ,  A61B2218/008 ,  A61F13/38 ,  C12Q1/025 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N1/2202 ,  G01N3/00 ,  G01N9/00 ,  G01N27/622 ,  G01N27/624 ,  G01N30/724 ,  G01N33/487 ,  G01N33/48735 ,  G01N33/6848 ,  G01N33/6851 ,  G01N33/92 ,  G01N2001/2223 ,  G01N2333/195 ,  G01N2405/00 ,  G01N2405/04 ,  G01N2405/08 ,  G01N2570/00 ,  G01N2800/26 ,  G06F19/324 ,  G06F19/3481 ,  G16B20/00 ,  G16H10/40 ,  G16H15/00 ,  G16H50/20 ,  H01J49/0004 ,  H01J49/0027 ,  H01J49/0031 ,  H01J49/0036 ,  H01J49/025 ,  H01J49/0404 ,  H01J49/0409 ,  H01J49/0422 ,  H01J49/044 ,  H01J49/0445 ,  H01J49/0459 ,  H01J49/0463 ,  H01J49/0468 ,  H01J49/061 ,  H01J49/068 ,  H01J49/10 ,  H01J49/14 ,  H01J49/16 ,  H01J49/164 ,  H01J49/24 ,  H01J49/26

Abstract: A method of mass spectrometry or ion mobility spectrometry is disclosed comprising: providing an analyte; supplying a matrix compound to said analyte such that said analyte dissolves in said matrix; forming first droplets of the dissolved analyte; and colliding said first droplets with a collision surface. The use of matrix improves the analyte ion signal.

公开(公告)号：US20230143849A1

公开(公告)日：2023-05-11

申请号：US18149468

申请日：2023-01-03

Applicant: Micromass UK Limited

Inventor： Zoltán TAKÁTS ,  Frances BOLT ,  Tamás KARANCSI ,  Emrys JONES ,  Keith RICHARDSON ,  Lajos GODORHAZY ,  Daniel SZALAY ,  Julia BALOG ,  Steven Derek PRINGLE ,  Daniel SIMON

IPC: H01J49/04 ,  A61B10/02 ,  A61B17/32 ,  A61B18/00 ,  A61B18/14 ,  A61B18/20 ,  G01N3/00 ,  G01N9/00 ,  G01N33/68 ,  H01J49/00 ,  H01J49/06 ,  H01J49/16 ,  G01N27/623 ,  A61B90/13 ,  A61B1/04 ,  A61B1/273 ,  A61B5/00 ,  A61B5/01 ,  A61B5/0507 ,  A61B5/055 ,  A61B6/03 ,  A61B8/13 ,  A61B10/00 ,  A61B17/00 ,  A61B18/04 ,  A61B18/18 ,  A61F13/38 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N1/22 ,  G01N27/624 ,  G01N30/72 ,  G01N33/487 ,  G01N33/92 ,  H01J49/02 ,  H01J49/10 ,  H01J49/14 ,  H01J49/24 ,  H01J49/26

CPC classification number: H01J49/049 ,  A61B10/0233 ,  A61B10/0283 ,  A61B17/320068 ,  A61B18/00 ,  A61B18/14 ,  A61B18/20 ,  G01N3/00 ,  G01N9/00 ,  G01N33/6848 ,  H01J49/0036 ,  H01J49/0404 ,  H01J49/0459 ,  H01J49/068 ,  H01J49/16 ,  H01J49/044 ,  G01N27/623 ,  A61B90/13 ,  A61B1/041 ,  A61B1/2736 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/015 ,  A61B5/0507 ,  A61B5/055 ,  A61B6/032 ,  A61B6/037 ,  A61B8/13 ,  A61B10/00 ,  A61B10/0041 ,  A61B17/00 ,  A61B18/04 ,  A61B18/042 ,  A61B18/1445 ,  A61B18/1815 ,  A61F13/38 ,  C12Q1/025 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N1/2202 ,  G01N27/624 ,  G01N30/724 ,  G01N33/487 ,  G01N33/6851 ,  G01N33/92 ,  H01J49/0004 ,  H01J49/0027 ,  H01J49/0031 ,  H01J49/025 ,  H01J49/0409 ,  H01J49/0422 ,  H01J49/0445 ,  H01J49/0463 ,  H01J49/0468 ,  H01J49/061 ,  H01J49/10 ,  H01J49/14 ,  H01J49/164 ,  H01J49/24 ,  H01J49/26 ,  G16B20/00

Abstract: A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed. The method comprises: using a first device to generate smoke, aerosol or vapour from a target comprising or consisting of a microbial population; mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and analysing said spectrometric data in order to analyse said microbial population.

公开(公告)号：US20220076937A1

公开(公告)日：2022-03-10

申请号：US17531490

申请日：2021-11-19

Applicant: Micromass UK Limited

Inventor： Zoltán TAKÁTS ,  Frances BOLT ,  Tamás KARANCSI ,  Emrys JONES ,  Keith RICHARDSON ,  Lajos GODORHAZY ,  Daniel SZALAY ,  Julia BALOG ,  Steven Derek PRINGLE ,  Daniel SIMON

IPC: H01J49/04 ,  A61B10/02 ,  A61B17/32 ,  A61B18/00 ,  A61B18/14 ,  A61B18/20 ,  G01N3/00 ,  G01N9/00 ,  G01N33/68 ,  H01J49/00 ,  H01J49/06 ,  H01J49/16 ,  A61B90/13 ,  A61B1/04 ,  A61B1/273 ,  A61B5/00 ,  A61B5/01 ,  A61B5/0507 ,  A61B5/055 ,  A61B6/03 ,  A61B8/13 ,  A61B10/00 ,  A61B17/00 ,  A61B18/04 ,  A61B18/18 ,  A61F13/38 ,  C12Q1/02 ,  C12Q1/04 ,  C12Q1/18 ,  C12Q1/24 ,  G01N1/22 ,  G01N27/622 ,  G01N27/624 ,  G01N30/72 ,  G01N33/487 ,  G01N33/92 ,  H01J49/02 ,  H01J49/10 ,  H01J49/14 ,  H01J49/24 ,  H01J49/26

Abstract: A method of analysis using mass spectrometry and/or ion mobility spectrometry is disclosed. The method comprises: using a first device to generate smoke, aerosol or vapour from a target comprising or consisting of a microbial population; mass analysing and/or ion mobility analysing said smoke, aerosol or vapour, or ions derived therefrom, in order to obtain spectrometric data; and analysing said spectrometric data in order to analyse said microbial population.

公开(公告)号：US20200258729A1

公开(公告)日：2020-08-13

申请号：US16862039

申请日：2020-04-29

Applicant: Micromass UK Limited

Inventor： Tamas KARANCSI ,  Daniel SIMON ,  Lajos GODORHAZY ,  Daniel SZALAY ,  Steven Derek PRINGLE ,  Emrys JONES ,  Ian TRIVETT ,  Stephen O'BRIEN ,  Anthony HESSE ,  Matt HENDERSON ,  Alvin CHUA ,  Zoltan TAKÁTS

IPC: H01J49/04 ,  G16H20/00 ,  G01N27/62 ,  A61B5/00 ,  H01J49/00 ,  G01N33/68 ,  G01N30/72 ,  G01N1/22 ,  C12Q1/24 ,  C12Q1/18 ,  C12Q1/04 ,  C12Q1/02 ,  A61B18/18 ,  A61B18/04 ,  A61B10/00 ,  A61B5/05 ,  A61B1/273 ,  G16H50/20 ,  G16H10/40 ,  H01J49/16 ,  H01J49/06 ,  G01N9/00 ,  G01N3/00 ,  A61B17/32 ,  A61B10/02

Abstract: An apparatus for performing ambient ionisation mass and/or ion mobility spectrometry is disclosed. The apparatus comprises a substantially cylindrical, tubular, rod-shaped, coil- shaped, helical or spiral-shaped collision assembly; and a first device arranged and adapted to direct analyte, smoke, fumes, liquid, gas, surgical smoke, aerosol or vapour onto said collision assembly.