公开(公告)号：JPH11116455A

公开(公告)日：1999-04-27

申请号：JP22888398

申请日：1998-08-13

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  HAREMZA SYLKE ,  SCHEHLMANN VOLKER DR ,  WESTENFELDER HORST ,  WUENSCH THOMAS DR ,  DROEGEMUELLER MICHAEL DR ,  BOMM VOLKER

IPC: A61K8/00 ,  A61K8/35 ,  A61K8/37 ,  A61K8/40 ,  A61K8/41 ,  A61K8/42 ,  A61K31/12 ,  A61K31/122 ,  A61K31/216 ,  A61K31/277 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C69/618 ,  C07C69/76 ,  C07C233/00 ,  C07C233/11 ,  C07C235/34 ,  A61K7/42

Abstract: PROBLEM TO BE SOLVED: To prepare a cosmetic or the like, having a high absorbance in the UV-A area, showing a high photoresistibility and high stability, capable of manifesting pleasant touch feeling by using a specific 4,4-diarylbutadiene with a well-known compound. SOLUTION: This compound is 4,4-diarylbutadiene of formula I [R and R are each H, a 1-20C alkyl, a 2-10C alkenyl, an aryl or the like; R is H, COOR (R is H, a 1-20C alkyl or the like), a 1-20C alkyl, CN or the like; R is COOR (R is same as R ), CN, a 1-20C alkyl or the like; (n) is 1-3], e.g. the compound of formula II. The compound of formula I is obtained by condensing a compound of formula III with a compound of formula IV. The compound of formula I itself is well-known, and is used together with a compound used as a sun-screening agent for preparations for cosmetics and pharmaceutical preparations. The compound of formula I is preferably used in the proportion of 0.1-10 wt.% based on the whole quantity of the preparation.

公开(公告)号：DE59907526D1

公开(公告)日：2003-12-04

申请号：DE59907526

申请日：1999-08-05

Applicant: BASF AG

Inventor： FISCHER DR ,  SIEGEL DR ,  BOMM VOLKER ,  MUNDINGER DR

IPC: C07C253/10 ,  C07C255/46 ,  C07D233/90

公开(公告)号：DE19836477A1

公开(公告)日：2000-02-17

申请号：DE19836477

申请日：1998-08-12

Applicant: BASF AG

Inventor： FISCHER JAKOB ,  SIEGEL WOLFGANG ,  BOMM VOLKER ,  FISCHER MARTIN ,  MUNDINGER KLAUS

IPC: C07D233/90

Abstract: 1,3-Dimethylimidazolium-4-carboxylate is produced by reacting 1-methyl-imidazole with dimethyl carbonate.

公开(公告)号：AU748711B2

公开(公告)日：2002-06-13

申请号：AU7997798

申请日：1998-08-13

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  HAREMZA SYLKE ,  SCHEHLMANN VOLKER ,  WESTENFELDER HORST ,  WUNSCH THOMAS ,  DROGEMULLER MICHAEL ,  BOMM VOLKER

IPC: A61K8/00 ,  A61K8/35 ,  A61K8/37 ,  A61K8/40 ,  A61K8/41 ,  A61K8/42 ,  A61K31/12 ,  A61K31/122 ,  A61K31/216 ,  A61K31/277 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C69/618 ,  C07C69/76 ,  C07C233/00 ,  C07C233/11 ,  C07C235/34 ,  A61K7/44 ,  A61K31/165 ,  A61K31/215 ,  C07C57/48 ,  C07C57/30

Abstract: Use of 4,4-diarylbutadienes (I) as photostable UV filters in cosmetics for protecting the skin and hair from the sun's rays. The use of 4,4-diarylbutadiene derivatives of formula (I) as a cosmetic preparation is new: Where the diene system is Z,Z; Z,E; E,Z or E,E; R1, R2 = H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, 1-12C alkoxy, 1-20C alkoxycarbonyl, 1-12C alkylamino, 1-12C dialkylamino, aryl, heteroaryl (optionally substituted by carboxylate, sulfonate or ammonium residues); R3 = H, COOR5, COR5, CONR5,R6, CN, O=S(R5)=O, O=S(OR5)=O, R7OP(OR8)=O, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 7-10C bicycloalkyl, 3-10C cycloalkenyl, 7-10C bicycloalkenyl, aryl or heteroaryl (optionally substituted); R4 = COOR6, COR6, CONR5,R6, CN, O=S(R6)=O, O=S(OR6)=O, R7OP(OR8)=O, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 7-10C bicycloalkyl, 3-10C cycloalkenyl, 7-10C bicycloalkenyl, aryl or heteroaryl (optionally substituted); R5-R8 = H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 7-10C bicycloalkyl, 3-10C cycloalkenyl, 7-10C bicycloalkenyl, aryl or heteroaryl (optionally substituted); and n = 1-3; where R3-R8 may in each case together with the C atoms to which they are bonded, form a 5- or 6-membered ring which may be further fused.

公开(公告)号：AU7997798A

公开(公告)日：1999-02-25

申请号：AU7997798

申请日：1998-08-13

Applicant: BASF AG

Inventor： HABECK THORSTEN ,  HAREMZA SYLKE ,  SCHEHLMANN VOLKER ,  WESTENFELDER HORST ,  WUNSCH THOMAS ,  DROGEMULLER MICHAEL ,  BOMM VOLKER

IPC: A61K8/00 ,  A61K8/35 ,  A61K8/37 ,  A61K8/40 ,  A61K8/41 ,  A61K8/42 ,  A61K31/12 ,  A61K31/122 ,  A61K31/216 ,  A61K31/277 ,  A61Q1/00 ,  A61Q1/04 ,  A61Q17/04 ,  C07C69/618 ,  C07C69/76 ,  C07C233/00 ,  C07C233/11 ,  C07C235/34 ,  A61K7/44 ,  A61K31/165 ,  A61K31/215 ,  C07C57/48 ,  C07C57/30

Abstract: Use of 4,4-diarylbutadienes (I) as photostable UV filters in cosmetics for protecting the skin and hair from the sun's rays. The use of 4,4-diarylbutadiene derivatives of formula (I) as a cosmetic preparation is new: Where the diene system is Z,Z; Z,E; E,Z or E,E; R1, R2 = H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 3-10C cycloalkenyl, 1-12C alkoxy, 1-20C alkoxycarbonyl, 1-12C alkylamino, 1-12C dialkylamino, aryl, heteroaryl (optionally substituted by carboxylate, sulfonate or ammonium residues); R3 = H, COOR5, COR5, CONR5,R6, CN, O=S(R5)=O, O=S(OR5)=O, R7OP(OR8)=O, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 7-10C bicycloalkyl, 3-10C cycloalkenyl, 7-10C bicycloalkenyl, aryl or heteroaryl (optionally substituted); R4 = COOR6, COR6, CONR5,R6, CN, O=S(R6)=O, O=S(OR6)=O, R7OP(OR8)=O, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 7-10C bicycloalkyl, 3-10C cycloalkenyl, 7-10C bicycloalkenyl, aryl or heteroaryl (optionally substituted); R5-R8 = H, 1-20C alkyl, 2-10C alkenyl, 3-10C cycloalkyl, 7-10C bicycloalkyl, 3-10C cycloalkenyl, 7-10C bicycloalkenyl, aryl or heteroaryl (optionally substituted); and n = 1-3; where R3-R8 may in each case together with the C atoms to which they are bonded, form a 5- or 6-membered ring which may be further fused.

公开(公告)号：BR0214549A

公开(公告)日：2004-11-03

申请号：BR0214549

申请日：2002-12-06

Applicant: BASF AG

Inventor： WESSEL HELGE ,  SEITZ VERENA ,  HARTH KLAUS ,  BOMM VOLKER ,  AUST NICOLA CHRISTIANE

IPC: B01J23/70 ,  B01J23/72 ,  B01J23/745 ,  B01J35/10 ,  B01J37/03 ,  B01J37/18 ,  C07B61/00 ,  C07C51/295 ,  C07C227/02 ,  C07C229/22 ,  C07C51/097

Abstract: Catalysts (I), for the production of carboxylic acid salts from alcohols, comprise (wt.%): (1) copper; or (2) copper (10-99.9), iron (0.01-90) and at least one other metal (0-50). Catalysts (I) are optionally doped. The hydroxide is prepared by precipitation of copper salt solutions (and/or copper and iron salt solutions with salts of at least one other metal (A)) by coprecipitation with a base and reduction with hydrogen. An Independent claim is included for a process for the production of carboxylic acid salts by reaction of an alcohol of formula (II) with an alkali hydroxide and/or alkaline earth metal hydroxide in water. The reaction is in the presence of a catalyst (I), at 120-280 deg C, and at a pressure between the vapor pressure of water and 75 bar. R = -(OCH2CH2OH) or -NR R ; and R , R = H, phenyl, -CH2CH2OH, 1-20 C alkyl or 2-5C dialkylamino.

公开(公告)号：AU748609B2

公开(公告)日：2002-06-06

申请号：AU5210998

申请日：1998-01-16

Applicant: BASF AG

Inventor： DROGEMULLER MICHAEL ,  BOMM VOLKER ,  SCHEHLMANN VOLKER ,  WESTENFELDER HORST

IPC: C07D215/42 ,  A61K8/00 ,  A61Q17/04 ,  C07C225/14 ,  C07C229/54 ,  C07C237/30 ,  C07C309/46 ,  C07C311/39 ,  C09K3/00 ,  C07C309/29 ,  C07C311/38 ,  A61K7/42 ,  A61K31/165 ,  A61K31/18 ,  A61K31/135 ,  A61K31/185 ,  A61K31/47

Abstract: Arylaminomethylene-camphor derivatives of formula (I) are new: R1 = H or Me; R2 = H, 1-6C alkyl, 3-8C cycloalkyl, 2-6C alkenyl; 3-8C cycloalkenyl or aryl (optionally substituted); R3 = H, 1-6C alkyl, 3-8C cycloalkyl, aryl (optionally substituted), 1-6C alkoxy or 1-8C acyl; and Ar = aryl or heteroaryl (both optionally substituted); NB the double bond is Z or E configuration.

公开(公告)号：DE59900401D1

公开(公告)日：2001-12-13

申请号：DE59900401

申请日：1999-08-05

Applicant: BASF AG

Inventor： FISCHER DR ,  SIEGEL DR ,  BOMM VOLKER ,  MUNDINGER DR

IPC: C07D233/90

公开(公告)号：DE19836474A1

公开(公告)日：2000-02-17

申请号：DE19836474

申请日：1998-08-12

Applicant: BASF AG

Inventor： FISCHER JAKOB ,  SIEGEL WOLFGANG ,  BOMM VOLKER ,  FISCHER MARTIN ,  MUNDINGER KLAUS

IPC: C07C253/10 ,  C07C255/46 ,  C07D233/90

公开(公告)号：MX9800488A

公开(公告)日：1998-10-31

申请号：MX9800488

申请日：1998-01-15

Applicant: BASF AG

Inventor： DROEGEMUELLER MICHAEL ,  BOMM VOLKER ,  SCHELMANN VOLKER ,  WESTENFELDER HORST

IPC: A61K8/00 ,  A61Q17/04 ,  C07C225/14 ,  C07D215/42 ,  C07C229/54 ,  C07C237/30 ,  C07C309/46 ,  C07C311/39 ,  C09K3/00 ,  A61K07/42 ,  C07C49/413

Abstract: Los derivados arilaminometilencanfor de la formula (I): en donde el doble enlace C=C se encuentra en la configuracion Z o E, y las variables tienen los siguientes significados: R1 H, CH3, R2 H, alquilo de C1-C6, cicloalquilo de C3-C8, alquenilo de C2-C6, cicloalquenilo de C3-C8, arilo o arilo sustituido, R3 H, alquilo de C1-C6, cicloalquilo de C3-C8, arilo, arilo sustituido, alcoxi de C1-C6, acilo de C1-C8, Ar arilo, arilo sustituido, hetarilo o hetarilo sustituido, se utilizan como agentes bloqueadores de los rayos solares, especialmente en formulaciones cosméticas y farmacéuticas.