中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

263 records (took 0.021 seconds)

    A METHOD, AN OPTICAL PROBE AND A CONFOCAL MICROSCOPY SYSTEM FOR INSPECTING A SOLID ORGAN
    91.
    发明专利
    A METHOD, AN OPTICAL PROBE AND A CONFOCAL MICROSCOPY SYSTEM FOR INSPECTING A SOLID ORGAN 未知

    公开(公告)号：CA2774621A1

    公开(公告)日：2011-03-24

    申请号：CA2774621

    申请日：2010-09-17

    Applicant: MAUNA KEA TECHNOLOGIES

    Inventor： BOULAROT NICOLAS ,  GENET MAGALIE ,  SCHWARZ FRANCE

    IPC: A61B1/04

    Abstract: A method to inspect a solid organ in a subject includes introducing a needle in a predetermined area of the solid organ, inserting an optical probe through a lumen of the needle, and imaging the predetermined area using the optical probe. An optical probe to inspect a solid organ in a subject, the optical probe being intended to be positioned in the solid organ through a needle, the optical probe includes an optical fiber bundle, a ferule to protect the distal tip of the optical fiber bundle, the ferule comprising a shank and a head, and a sheath wrapping the fiber bundle and the shank, wherein the head of the ferule has a length adapted for the optical probe to image the solid organ while keeping the sheath inside the needle.

    CONFOCAL IMAGING EQUIPMENT IN PARTICULAR FOR ENDOSCOPE
    93.
    发明专利
    CONFOCAL IMAGING EQUIPMENT IN PARTICULAR FOR ENDOSCOPE 未知

    公开(公告)号：IL162706A

    公开(公告)日：2010-04-29

    申请号：IL16270604

    申请日：2004-06-23

    Applicant: MAUNA KEA TECHNOLOGIES

    IPC: G02B23/26 ,  A61B1/00 ,  A61B1/04 ,  A61B1/07 ,  G02B21/00 ,  G02B23/24

    Abstract: Equipment includes an image guide ( 1 ) consisting of flexible optical fibers with: on the proximal end side: a source ( 2 ), angular scanning elements ( 3 ), injection elements ( 4 ) in one of the fibers, elements for splitting ( 5 ) the illuminating beam and the backscattered signal, elements for spatial filtering ( 6 ), elements for detecting ( 7 ) the signal, electronic elements ( 8 ) for controlling, analyzing and digital processing of the detected signal and display; and on the distal end side: an optical head ( 9 ) for focusing the illuminating beam exiting from the illuminated fiber. The scanning elements include a resonant line mirror (M 1 ) and a galvanometric field mirror (M 2 ) with a variable frequency and two afocal optical systems adapted to conjugate the two mirrors (M 1 , M 2 ) firstly in the field mirror (M 2 ) and the injection elements ( 4 ) in the image guide in a second step.

    94.
    发明专利
    未知

    公开(公告)号：AT448731T

    公开(公告)日：2009-12-15

    申请号：AT05717461

    申请日：2005-01-21

    Applicant: CENTRE NAT RECH SCIENT ,  OBSERVATOIRE PARIS ,  MAUNA KEA TECHNOLOGIES

    Inventor： LACOMBE FRANCOIS ,  LAFAILLE DAVID ,  GLANC MARIE ,  GENDRON ERIC

    IPC: A61B3/12 ,  G01B9/02

    Abstract: The system has a deformable mirror placed between a Michelson interferometer and the eye, to compensate geometric aberrations of the eye. A focalization regulating unit regulates focalization of Shack-Hartmann analyzer, and forces the mirror to bend in order to conjugate an input light source and a detector with a predetermined depth point in retina. The unit is controlled in synchronism with scanning of tomography arrangement. An independent claim is also included for an in vivo tomography method for human retina.

    95.
    发明专利
    未知

    公开(公告)号：FR2900741B1

    公开(公告)日：2008-07-18

    申请号：FR0604019

    申请日：2006-05-05

    Applicant: MAUNA KEA TECHNOLOGIES SOC PAR

    Inventor： GENET MAGALIE ,  MATHIEU GILLES ,  VIELLEROBE BERTRAND ,  DOUSSOUX FRANCOIS ,  BOULAROT NICOLAS ,  LAVILLONNIERE NICOLAS

    IPC: G02B23/24 ,  A61B1/00

    Abstract: A miniaturized optical head provided to equip the distal end of a beam of flexible optical fibers scanned by a laser beam, is designed to come in contact with a sample and to excite the sample confocally. This optical head includes elements for correcting spherical aberrations and focusing members. The focusing members include: at least a first lens (L4) of high convergence associated with a spherical or hemispherical lens (L5) arranged at the distal end of the optical head, and elements for correcting the axial and lateral chromatic aberration provided with a single divergent lens (3b) whose curvature is substantially centered on the pupil of the optical fiber beam and arranged at the exact distance for this pupil for which the conditions of lateral achromatization coincide with the conditions of axial achromatization; this divergent lens being associated with a second convergent lens (L3a) in the form of a doublet (L3).

    96.
    发明专利
    未知

    公开(公告)号：FR2871358B1

    公开(公告)日：2007-02-09

    申请号：FR0406396

    申请日：2004-06-14

    Applicant: MAUNA KEA TECHNOLOGIES SOC PAR

    Inventor： VIELLEROBE BERTRAND ,  JEAN FLORENCE ,  BOURG HECKLY GENEVIEVE ,  LOISEAU ALEXANDRE

    IPC: A61B5/00 ,  G01N21/64 ,  G02B21/00 ,  G02B23/26

    Abstract: The invention relates to a method for producing a fluorescent fiber image of a sample, wherein a sample is scanned with the aid of an excitation signal; the fluorescent signal emanating from the sample is detected, wherein the excitation signal and fluorescent signal use the same optical path; the optical path is used to excite at least two fluorophores contained in the sample; a final image is produced, including areas that are colored according to the at least two fluorophores. The multimarking according to the invention makes it possible to simultaneously acquire two images in two different wavelength bands. The system according to the invention can comprise a spectrometer for spectral quantification of the fluorescent signal.

    97.
    发明专利
    未知

    公开(公告)号：DE60205408T2

    公开(公告)日：2006-06-01

    申请号：DE60205408

    申请日：2002-12-20

    Applicant: MAUNA KEA TECHNOLOGIES

    Inventor： VIELLEROBE BERTRAND ,  GENET MAGALIE ,  BERIER FREDERIC ,  LACOMBE FRANCOIS ,  PERCHANT AYMERIC ,  LE GOUALHER GEORGES ,  MARTI SANDRA ,  BOURRIAUX STEPHANE

    IPC: G02B23/24 ,  G02B23/26 ,  A61B1/00 ,  A61B1/04 ,  A61B1/07 ,  G02B21/00

    Abstract: Equipment includes an image guide ( 1 ) consisting of flexible optical fibers with: on the proximal end side: a source ( 2 ), angular scanning elements ( 3 ), injection elements ( 4 ) in one of the fibers, elements for splitting ( 5 ) the illuminating beam and the backscattered signal, elements for spatial filtering ( 6 ), elements for detecting ( 7 ) the signal, electronic elements ( 8 ) for controlling, analyzing and digital processing of the detected signal and display; and on the distal end side: an optical head ( 9 ) for focusing the illuminating beam exiting from the illuminated fiber. The scanning elements include a resonant line mirror (M 1 ) and a galvanometric field mirror (M 2 ) with a variable frequency and two afocal optical systems adapted to conjugate the two mirrors (M 1 , M 2 ) firstly in the field mirror (M 2 ) and the injection elements ( 4 ) in the image guide in a second step.

    99.
    发明专利
    未知

    公开(公告)号：AT320614T

    公开(公告)日：2006-04-15

    申请号：AT02801158

    申请日：2002-12-20

    Applicant: MAUNA KEA TECHNOLOGIES

    Inventor： BERIER FREDERIC ,  BOURRIAUX STEPHANE ,  GENET MAGALIE ,  VIELLEROBE BERTRAND ,  LOISEAU ALEXANDRE ,  ABRAT BENJAMIN

    IPC: G02B23/26 ,  A61B1/00 ,  G02B21/02 ,  G02B23/24 ,  A61B1/07

    Abstract: An optical head for equipping the distal end of a flexible optical fiber bundle, designed to be urged into contact with an analyzing surface and including optical elements for focusing an excitation signal into a so-called excitation focal point located at a specific depth beneath the analyzing surface and for sampling a signal backscattered by the excitation focal point which is carried back by the fiber bundle. The head includes an optics-holder tube wherein are inserted on one side the distal end portion of the fiber bundle and on the other optical elements, the latter including a plate placed in contact with the end of the fiber bundle whereof the index is close to that of the fiber core and a focusing optical block, an output window being further provided adapted to provide index adaptation so as to eliminate parasitic reflection occurring on the analyzing surface.

    Multimarking fiber fluorescence microscopic imagery system and method
    100.
    发明专利
    Multimarking fiber fluorescence microscopic imagery system and method 未知

    公开(公告)号：AU2005256758A1

    公开(公告)日：2006-01-05

    申请号：AU2005256758

    申请日：2005-06-09

    Applicant: MAUNA KEA TECHNOLOGIES

    Inventor： BOURG-HECKLY GENEVIEVE ,  VIELLEROBE BERTRAND ,  JEAN FLORENCE ,  LOISEAU ALEXANDRE

    IPC: G01N21/64 ,  A61B5/00 ,  G02B21/00 ,  G02B23/26

    Abstract: The invention relates to a method for producing a fluorescent fiber image of a sample, wherein a sample is scanned with the aid of an excitation signal; the fluorescent signal emanating from the sample is detected, wherein the excitation signal and fluorescent signal use the same optical path; the optical path is used to excite at least two fluorophores contained in the sample; a final image is produced, including areas that are colored according to the at least two fluorophores. The multimarking according to the invention makes it possible to simultaneously acquire two images in two different wavelength bands. The system according to the invention can comprise a spectrometer for spectral quantification of the fluorescent signal.

Patent Agency Ranking