公开(公告)号：KR1020040085844A

公开(公告)日：2004-10-08

申请号：KR1020030020667

申请日：2003-04-02

Applicant: 한국식품연구원

Inventor： 최희돈 ,  석호문 ,  박용곤 ,  김성란 ,  김윤숙 ,  최인욱

IPC: A23L1/182

CPC classification number: A23L7/196 ,  A23V2250/038

Abstract: PURPOSE: Provided is a method for manufacturing brown rice which contains a large quantity of nutritious components including gamma-aminobutyric acid(GABA) and ferulic acid(FA) increased by 2.2 times and 1.5 times, respectively. CONSTITUTION: The method for manufacturing brown rice which contains a large quantity of nutritious components comprises the steps of: dipping brown rice in glutamate solution (pH 4-7) of 35-45 deg.C for 6-10 hours; and leaving the brown rice under anaerobic condition for 1-2 hours.

Abstract translation: 目的：提供一种含有γ-氨基丁酸（GABA）和阿魏酸（FA）的大量营养成分分别增加了2.2倍和1.5倍的糙米的方法。 构成：含有大量营养成分的糙米的制造方法包括以下步骤：将糙米在35-45℃的谷氨酸溶液（pH 4-7）中浸泡6-10小时; 并将糙米置于无氧条件下1-2小时。

公开(公告)号：KR100381389B1

公开(公告)日：2003-04-26

申请号：KR1020000085064

申请日：2000-12-29

Applicant: 경상북도 울릉군 ,  한국식품연구원

Inventor： 박용곤 ,  김흥만 ,  최인욱 ,  최희돈 ,  김성란

IPC: A23F3/32

Abstract: PURPOSE: A method for producing Sorbus commixta fruit tea is provided, therefore the tea can contain all active ingredients in Sorbus commixta fruit to easily use the pharmaceutical efficacies of Sorbus commixta fruit. CONSTITUTION: The method for producing Sorbus commixta fruit tea comprises the steps of: adding 400 to 500 parts by weight of water into 100 parts by weight of Sorbus commixta fruits and boiling the mixture for 90 to 120 minutes; filtering the boiled solution with a 18 mesh sieve to separate a filtrate from cooked Sorbus commixta fruits; pressing the cooked commixta fruits on the sieve to remove skin and seeds and obtain fruit juice; mixing the filtrate and fruit juice and filtering the mixture with a 60 mesh sieve; and adding 0.15 to 0.25 parts by weight of agar and 0.09 to 0.10 parts by weight of solstar.

Abstract translation: 用途：本发明提供了一种生产花楸果茶的方法，因此该花可以在花楸果实中含有所有活性成分，容易地利用花楸果实的药效。 本发明公开了一种生产花楸果实茶的方法，包括以下步骤：将400〜500重量份的水加入100重量份花楸果实中，煮沸90〜120分钟; 用18目筛过滤煮沸的溶液以从熟楸果实中分离出滤液; 在筛上压熟的commixta果实以去除皮肤和种子并获得果汁; 将滤液和果汁混合并用60目筛过滤混合物; 并加入0.15-0.25重量份的琼脂和0.09-0.10重量份的solstar。

公开(公告)号：KR1020000067028A

公开(公告)日：2000-11-15

申请号：KR1019990014485

申请日：1999-04-22

Applicant: 주식회사 열림기술 ,  한국식품연구원

Inventor： 박용곤 ,  김흥만 ,  차환수 ,  최인욱

IPC: A23L1/29

Abstract: PURPOSE: Caramel shaped food helping diet that slows hunger down and oxidizes body fat without the strain is provided. CONSTITUTION: The auxiliary food for diet includes 20-55wt% of palatinit, 20-55wt% of maltitol syrup, 0.1-5wt% of free acid shape of hydroxy citric acid, 10-20wt% of dietary fiber and has a form of caramel. 0.1-5wt% of an extract of green tea and 0.05-3wt% of Gymnema acid can be added for improving favor, preventing decayed tooth and glycosuria and absorbing sugar content.

Abstract translation: 目的：焦糖形食物有助于减轻饥饿和减轻身体脂肪而减轻身体脂肪，减轻疲劳。 构成：膳食辅助食品包括20-55％的palatinit，20-55wt％的麦芽糖醇糖浆，0.1-5wt％的游离酸形式的羟基柠檬酸，10-20wt％的膳食纤维，并且具有焦糖的形式。 可以添加0.1-5％的绿茶提取物和0.05-3％（重量）的肌肉酸，以改善有利的作用，防止腐烂的牙齿和糖尿并吸收糖分。

公开(公告)号：KR1020000060857A

公开(公告)日：2000-10-16

申请号：KR1019990009500

申请日：1999-03-20

Applicant: 한국식품연구원

Inventor： 최인욱 ,  김윤지 ,  성기승 ,  전기홍

IPC: A61K35/16

CPC classification number: A61K35/16

Abstract: PURPOSE: A preparation method of an iron-transferrin extract is provided. The method is used to increase the bioavailability of the iron and solubility of the iron in the duodenum, and comprises the simplified steps. Because of its thermal stability and sterilizability, the resulting iron-transferrin extract can readily be contained to a various medical iron preparation and an iron-reinforcing agent. CONSTITUTION: The preparation method of an iron-transferrin extract comprises the steps of: carrying out an ion-exchange chromatography of the plasma from the slaughtered animal blood using the resin such as Sepharose, Sephadex or Sephacel to separate transferrin-containing fraction; filtering and lyophilizing the transferrin-containing fraction to obtain the concentrated transferrin extract powder; and adding iron in the form of FeCl3, FeSO4, ferric citrate, ferric lactate, ferrous citrate or ferrous lactate to the diluted transferrin extract solution followed by dialyzing, sterilizing and lyophilizing to obtain the iron-transferrin extract in the form of the powder.

Abstract translation: 目的：提供铁 - 铁蛋白提取物的制备方法。 该方法用于提高铁的生物利用度和铁在十二指肠中的溶解度，并且包括简化的步骤。 由于其热稳定性和杀菌性，所得到的铁 - 铁蛋白提取物可以容易地包含在各种医用铁制剂和铁增强剂中。 构成：铁 - 铁蛋白提取物的制备方法包括以下步骤：使用树脂如Sepharose，Sephadex或Sephacel对来自屠宰动物血液的血浆进行离子交换层析，以分离含有转铁蛋白的级分; 过滤并冻干含有转铁蛋白的级分以获得浓缩的转铁蛋白提取物粉末; 并向稀释的转铁蛋白提取液中加入FeCl3，FeSO4，柠檬酸铁，乳酸三钙，柠檬酸亚铁或乳酸亚铁的铁，然后进行透析，灭菌和冻干，得到粉末形式的铁 - 铁蛋白提取物。

公开(公告)号：KR101949741B1

公开(公告)日：2019-02-19

申请号：KR1020170052397

申请日：2017-04-24

Applicant: 한국식품연구원 ,  숙명여자대학교산학협력단

Inventor： 최희돈 ,  최인욱 ,  이광민 ,  하상근 ,  김병희 ,  김지원

IPC: C12P19/44 ,  C07H15/02 ,  A23L33/12

公开(公告)号：KR101803325B1

公开(公告)日：2017-12-05

申请号：KR1020160111344

申请日：2016-08-31

Applicant: 홍익대학교 산학협력단 ,  한국식품연구원

Inventor： 성종환 ,  이동욱 ,  최인욱 ,  하상근

IPC: C12M3/06 ,  C12M1/00

CPC classification number: C12M23/16 ,  C12M29/18

Abstract: 미세유체칩이개시되며, 상기미세유체칩은, 일측에형성되는주입리저버; 타측에형성되되, 저면이상기주입리저버의저면보다높은위치에형성되는배출리저버; 타측방향으로의제1 기울임상태가되면상기주입리저버로부터상기배출리저버로의유체의정 방향흐름이형성되는주 채널; 및일측방향으로의제2 기울임상태가되면상기배출리저버로부터상기주입리저버로의유체의역 방향흐름이형성되는우회채널을포함하되, 상기우회채널은상기주 채널보다높은위치에형성된다.

公开(公告)号：KR1020170106546A

公开(公告)日：2017-09-21

申请号：KR1020160028883

申请日：2016-03-10

Applicant: 한국식품연구원

Inventor： 최인욱 ,  하상근 ,  이애신 ,  박호영 ,  최희돈 ,  이진아 ,  조은정

IPC: A61K36/48 ,  A61K31/352 ,  A23L1/30

Abstract: 본발명은, 땅콩껍질추출물을유효성분으로포함하는염증성장질환의예방또는치료용조성물에관한것이다. 본발명의의하면, 천연물로부터유래된것으로, 난치성질환인염증성장질환의치료및 예방에탁월한효과를가지는추출물을포함하는조성물및 그추출물을포함한염증성장질환치료및 예방을위한약학조성물과염증성장질환의예방또는개선을위한건강기능식품을제공할수 있다.

Abstract translation: 本发明涉及含有花生树皮提取物作为有效成分的炎症性生长疾病的预防或治疗用组合物。 根据本发明，为被从天然产物，炎症，其具有：用于预防和治疗生长障碍和药物组合物用于炎症性肠疾病的治疗和预防，包括提取物和IBD的优异效果的提取物的组合物的疑难杂症衍生 可以提供用于预防或改善保健功能食品的保健功能食品。

公开(公告)号：KR101769828B1

公开(公告)日：2017-08-21

申请号：KR1020160044948

申请日：2016-04-12

Applicant: 한국식품연구원

Inventor： 최상윤 ,  김상희 ,  최인욱

IPC: A61K31/36 ,  A61K31/16 ,  A61K31/167 ,  A23L1/30

CPC classification number: A61K31/36 ,  A23L33/10 ,  A23V2002/00 ,  A23V2200/326 ,  A23V2200/332 ,  A61K31/16 ,  A61K31/167

Abstract: 본발명은 (E)-3-(벤조[d][1,3]디옥솔-5-일)-N-(4-하이드록시페네틸)아크릴아마이드및 이의유도체들을함유하는항비만조성물에관한것이다. 본발명의 (E)-3-(벤조[d][1,3]디옥솔-5-일)-N-(4-하이드록시페네틸)아크릴아마이드및 이의유도체들은인 비트로(in vitro) 상에서세포독성을나타내지않으면서지방세포분화를억제하고, 비만관련인자인 FAS의발현을억제하며, PPAR-γ의활성및 발현을억제하였고, 인비보(in vivo) 상에서도간 독성을나타내지않으면서사료섭취량및 체중증가량, 지방세포크기, 및혈중중성지방함량을감소시켰으므로우수한항비만효과를가진다. 따라서본 발명의화합물은비만또는지질대사와관련된질환(고지혈증, 심혈관질환, 동맥경화증등)을예방, 치료및 개선할수 있는소재로서약리학적조성물과같은의약품은물론이고, 건강기능식품등으로활용할수 있어식품산업및 의약산업에응용될경우그 가치가매우높을것으로기대된다.

公开(公告)号：KR101713095B1

公开(公告)日：2017-03-08

申请号：KR1020150108656

申请日：2015-07-31

Applicant: 한국식품연구원

Inventor： 하상근 ,  박호영 ,  박용곤 ,  최인욱 ,  이상훈 ,  조웅제 ,  최지원 ,  유혜현 ,  조수경 ,  오명숙

IPC: A61K36/9068 ,  A23L29/00 ,  A23L1/30 ,  A61K31/05 ,  A61K31/045

Abstract: 본발명은생강을스키조사카로마이세스폼베로발효하여얻은배양액의인지기능장애예방또는치료효과에관한것으로, 특정대사체비율을가지는본 발명의생강발효물은 Aβ올리고머및 Aβ플라크에의한독성으로부터세포를보호하고, Aβ응집을억제하고, 학습능력, 공간기억력, 공포기억력을개선하는효과가있어알츠하이머병을포함한 Aβ관련질환인인지기능장애의예방및 치료에이용될수 있다.

公开(公告)号：KR101706754B1

公开(公告)日：2017-02-15

申请号：KR1020140134780

申请日：2014-10-07

Applicant: 한국식품연구원

Inventor： 김윤숙 ,  박용곤 ,  최인욱 ,  최희돈 ,  이상훈 ,  전현진 ,  이광원 ,  양성용

IPC: A23L17/20 ,  A23L33/00 ,  A23L1/30 ,  C12N9/60 ,  A24B15/30

Abstract: 본발명은항원성이저감되고항산화활성이우수한당화어류단백분해물및 이의제조방법에관한것으로내장이제거된어류부산물또는어류단백질을단백질분해효소로가수분해하는단계; 및상기가수분해된가수분해물과당류를혼합하여마이얄(Maillaird)반응시키는단계;를포함함으로써, 우수한항산화활성및 알러지저감효과를가질수 있다.

Abstract translation: 本发明涉及具有降低的抗原性和改善的抗氧化活性的糖化鱼蛋白残留产物及其制备方法。 根据本发明，制备具有降低的抗原性和改善的抗氧化活性的糖化鱼蛋白残留产物的方法包括：通过蛋白水解酶水解除去肠内的鱼的副产物或蛋白质的步骤; 和通过将水解物质与糖混合的美拉德反应步骤。 因此，可以获得优异的抗氧化活性并且可以降低过敏。