公开(公告)号：AU2005230544A1

公开(公告)日：2005-10-20

申请号：AU2005230544

申请日：2005-03-25

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： LACOMBE FRANCOIS ,  GOUALHER GEORGES LE ,  AYACHE NICHOLAS ,  PERCHANT AYMERIC

IPC: G01F1/00 ,  A61B3/12 ,  G01F1/708 ,  G01N15/14 ,  G01S15/89 ,  G02B21/00

Abstract: The invention relates to a method for measuring the speed of a particle such as a red blood cell moving inside a flow such as a flow of the blood, using a light scanning microscope. The inventive method comprises the following steps: acquisition of an image by x and y light scanning on a plane containing the object; detection on the plane (x, y) of a mark on the plane (x, y); estimation of the speed vg of the object from the gradient thus determined.

公开(公告)号：FR2865371A1

公开(公告)日：2005-07-29

申请号：FR0400581

申请日：2004-01-22

Applicant: CENTRE NAT RECH SCIENT ,  OBSERVATOIRE PARIS ,  MAUNA KEA TECHNOLOGIES

Inventor： LACOMBE FRANCOIS ,  LAFAILLE DAVID ,  GLANC MARIE ,  GENDRON ERIC ,  STEFANOVITCH DOUCHANE

IPC: A61B3/00 ,  A61B3/12 ,  A61B3/14

Abstract: The device includes an active test pattern (MAM), a movable target and a programmable trajectory. The movable target is displayed on a screen of a desktop computer, where the target is visible to an eye of a subject during a testing period. The target is constituted of set of concentric circles and an aiming mark at the center of the circles. Independent claims are also included for the following: (A) a method of sight for testing eye of a subject (B) an eye testing system using tomography in vivo.

公开(公告)号：FR2864438A1

公开(公告)日：2005-07-01

申请号：FR0315627

申请日：2003-12-31

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： MATHIEU GILLES ,  GENET MAGALIE ,  VIELLEROBE BERTRAND ,  BERIER FREDERIC

IPC: A61B1/00 ,  A61B1/005 ,  A61B1/04 ,  A61B1/05 ,  A61B5/00 ,  G02B6/26 ,  G02B6/35 ,  G02B7/02 ,  G02B21/00 ,  G02B26/10 ,  A61B1/07 ,  G02B6/06 ,  G02B26/08 ,  H01J3/14

Abstract: The head has a laser source to produce a light beam (13), and a ball lens (12), with a large numerical aperture, disposed at the end of the head to converge the beam at an excitation point (19). The point is located in an observed sub-surface field (14) of a sample (15). A scanning unit (10) displaces the source in rotation such that the point scans the field. An independent claim is also included for a confocal imaging system.

公开(公告)号：AU2003273437A1

公开(公告)日：2004-02-09

申请号：AU2003273437

申请日：2003-07-11

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： CLADE SOPHIE ,  GENET MAGALIE ,  VIELLEROBE BERTRAND ,  BERIER FREDERIC

IPC: G01N21/64 ,  A61B1/00 ,  A61B1/04 ,  A61B5/00 ,  G02B21/00 ,  G02B23/24 ,  G02B23/26 ,  G02B26/10 ,  H04N1/028

Abstract: The method consists in deflecting the excitation signal at a speed corresponding to acquisition of a number of images per second sufficient for real time use and in detecting the fluorescence signal at a detecting frequency corresponding to a minimum frequency for sampling the fibers one by one. The method uses an image guide consisting of several thousands of optical fibers, an excitation signal being emitted by a source, deflected and injected by turns into the optical fibers of the guide, each excitation point of the tissue in the fiber output emitting in return a fluorescence signal collected by the fiber, then detected and digitized to form an image element. The method also provides for the focussing of the beam in the fiber output to excite a subsurface plane to produce a confocal image. The method also provides for the production of a divergent beam in the fiber output capable of exciting a micro-volume of the tissue from the surface.

公开(公告)号：FR2834349A1

公开(公告)日：2003-07-04

申请号：FR0116980

申请日：2001-12-28

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： VIELLEROBE BERTRAND ,  GENET MAGALIE ,  BERIER FREDERIC ,  LACOMBE FRANCOIS ,  PERCHANT AYMERIC ,  LE GOUALHER GEORGES ,  MARTI SANDRA ,  BOURRIAUX STEPHANE

IPC: G02B23/26 ,  A61B1/00 ,  A61B1/04 ,  A61B1/07 ,  G02B21/00 ,  G02B23/24 ,  G02B26/10 ,  G06F19/00

Abstract: Equipment includes an image guide ( 1 ) consisting of flexible optical fibers with: on the proximal end side: a source ( 2 ), angular scanning elements ( 3 ), injection elements ( 4 ) in one of the fibers, elements for splitting ( 5 ) the illuminating beam and the backscattered signal, elements for spatial filtering ( 6 ), elements for detecting ( 7 ) the signal, electronic elements ( 8 ) for controlling, analyzing and digital processing of the detected signal and display; and on the distal end side: an optical head ( 9 ) for focusing the illuminating beam exiting from the illuminated fiber. The scanning elements include a resonant line mirror (M 1 ) and a galvanometric field mirror (M 2 ) with a variable frequency and two afocal optical systems adapted to conjugate the two mirrors (M 1 , M 2 ) firstly in the field mirror (M 2 ) and the injection elements ( 4 ) in the image guide in a second step.

公开(公告)号：FR2834348A1

公开(公告)日：2003-07-04

申请号：FR0116979

申请日：2001-12-28

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： BERIER FREDERIC ,  BOURRIAUX STEPHANE ,  GENET MAGALIE ,  VIELLEROBE BERTRAND ,  LOISEAU ALEXANDRE ,  ABRAT BENJAMIN

IPC: G02B23/26 ,  A61B1/00 ,  G02B21/02 ,  A61B1/07

Abstract: An optical head for equipping the distal end of a flexible optical fiber bundle, designed to be urged into contact with an analyzing surface and including optical elements for focusing an excitation signal into a so-called excitation focal point located at a specific depth beneath the analyzing surface and for sampling a signal backscattered by the excitation focal point which is carried back by the fiber bundle. The head includes an optics-holder tube wherein are inserted on one side the distal end portion of the fiber bundle and on the other optical elements, the latter including a plate placed in contact with the end of the fiber bundle whereof the index is close to that of the fiber core and a focusing optical block, an output window being further provided adapted to provide index adaptation so as to eliminate parasitic reflection occurring on the analyzing surface.

公开(公告)号：FR2834340A1

公开(公告)日：2003-07-04

申请号：FR0116981

申请日：2001-12-28

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： GENET MAGALIE ,  BOURG HECKLY GENEVIEVE ,  VILETTE SANDRINE ,  LACOMBE FRANCOIS ,  LOISEAU ALEXANDRE ,  ABRAT BENJAMIN

IPC: A61B1/00 ,  A61B5/00 ,  G01N21/64 ,  G01N33/483 ,  A61B1/07

Abstract: An equipment includes an excitation source ( 1 ), elements for injecting ( 2 ) an excitation signal produced by the source in an ordered bundle ( 3 ) of flexible optical fibers, elements for analyzing ( 21, 22 ) an emitted autofluorescence signal. The equipment also includes at the output of the optical fiber bundle ( 3 ) an optical head ( 4 ) designed to be placed in contact with the biological tissue ( 6 ), the optical head being equipped with optical elements adapted to cause the excitation signal output from the bundle ( 3 ) to converge into a subsurface analyzing zone ( 5 ), the same optical fiber(s) used for excitation of the bundle ( 3 ) being used for detecting the signal emitted by the subsurface analyzing zone, elements (D) placed upstream of the injection elements ( 2 ) being further provided to separate the wavelength of the excitation signal and the wavelength of the autofluorescence signal.

公开(公告)号：CA2923991A1

公开(公告)日：2015-04-16

申请号：CA2923991

申请日：2014-10-13

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： LINARD NICOLAS ,  ANDRE BARBARA ,  DAUGUET JULIEN ,  VERCAUTEREN TOM

IPC: G06T7/00

Abstract: According to a first aspect, the invention relates to a method to support clinical decision by characterizing images acquired in sequence through a video medical device. The method comprises defining at least one image quantitative criterion, storing sequential images in a buffer, for each image (10) in the buffer, automatically determining, using a first algorithm, at least one output based on said image quantitative criterion and attaching said output to a timeline (11).

公开(公告)号：ES2524480T3

公开(公告)日：2014-12-09

申请号：ES10768547

申请日：2010-07-19

Applicant: MAUNA KEA TECHNOLOGIES

Inventor： BOULAROT NICOLAS ,  CRESSANT ARNAUD

IPC: A61B1/00 ,  A61B1/313 ,  A61B5/00 ,  A61B19/00 ,  G02B23/26

Abstract: Un implante intracraneal (1) para colocar un manojo de fibras de una sonda de manojo de fibras en una región especificada de un cerebro de un animal, en donde la sonda de manojo de fibras comprende además un casquillo dispuesto en una parte distal del manojo de fibras, el implante intracraneal (1) comprende: un soporte de base (11) para ser fijado a un cráneo del animal sobre un orificio taladrado en el cráneo; un conducto hueco (12) dispuesto a través de la base de soporte (11) para guiar el manojo de fibras al cerebro del animal a través del orificio taladrado; un primer miembro de trabado (100) dispuesto en la base de soporte (11), para cooperar con el casquillo de la sonda de manojo de fibras, el primer miembro de trabado (100) se configura para trabar el manojo de fibras en la región especificada del cerebro del animal, caracterizado porque el primer miembro de trabado (100) comprende un pasador (13) substancialmente perpendicular al soporte de base (11).

公开(公告)号：CA2553743C

公开(公告)日：2014-07-22

申请号：CA2553743

申请日：2005-01-21

Applicant: CENTRE NAT RECH SCIENT ,  OBSERVATOIRE PARIS ,  MAUNA KEA TECHNOLOGIES

Inventor： LACOMBE FRANCOIS ,  LAFAILLE DAVID

IPC: G01B9/02 ,  A61B3/12

Abstract: Dispositif pour mesurer le contraste des franges dans un interféromètre de Michelson en plein champ, comprenant un prisme de Wollaston pour dévier deux polarisations perpendiculaires entrantes dans deux directions émergeantes différentes, ces moyens de déviation étant disposés au sein de l'interféromètre en substitution d'un polariseur unique. Ce dispositif est appliqué dans un interféromètre de Michelson mis en oeuvre dans un système de tomographie OCT et comprenant des moyens d'extraction du contraste interférométrique n'employant aucune technique de modulation ni des méthodes de détection synchrone.