公开(公告)号：BRPI0514167A

公开(公告)日：2008-06-03

申请号：BRPI0514167

申请日：2005-08-02

Applicant: BASF AG

Inventor： LANG-WITTKOWSKI GABRIELE ,  JAHNS EKKEHARD ,  SCHMIDT MARCO ,  SENGE MICHAEL ,  STEFFEN MARKUS ,  KOLTER KARL

IPC: C09K5/06 ,  B01J13/00 ,  C04B20/10 ,  F28D20/02

Abstract: The present invention relates to a coarsely divided microcapsule preparation with particles whose particle sizes are in the range from 200 μm to 5 cm, comprising microcapsules with a capsule core of latent heat storage material and a thermosetting polymer as capsule wall and one or more polymeric binders whose binder polymer has thermoplastic properties and film-forming properties under processing conditions, where the binder content, calculated as solid, is 1-30% by weight, based on the total weight of the coarsely divided microcapsule preparation.

公开(公告)号：AT385783T

公开(公告)日：2008-03-15

申请号：AT00125170

申请日：2000-11-18

Applicant: BASF AG

Inventor： KOLTER KARL ,  SCHEIFFELE SILKE ,  EINIG HEINZ ,  BODMEIER ROLAND

IPC: A61K9/28 ,  C07D233/06 ,  A61K9/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/26 ,  A61K9/32 ,  A61K9/50 ,  A61K31/135 ,  A61K31/137 ,  A61K31/167 ,  A61K31/192 ,  A61K31/341 ,  A61K31/4164 ,  A61K31/426 ,  A61K31/4402 ,  A61K31/4418 ,  A61K31/451 ,  A61K31/485 ,  A61K31/616 ,  A61K45/00 ,  A61K47/04 ,  A61K47/12 ,  A61K47/32 ,  A61K47/36 ,  A61K47/38 ,  A61P11/00 ,  A61P25/06 ,  A61P37/08 ,  C07D211/52 ,  C07D213/38 ,  C07D221/28 ,  C07D277/20 ,  C07D277/28 ,  C07D277/42 ,  C07D307/52

Abstract: A film coating containing polyvinyl acetate and hydrophilic additives is used for masking the flavor of oral administration forms. The film coating consists of: (a) polyvinyl acetate (PVA); (b) hydrophilic additives; (c) usual coating components; and optionally (d) a physiologically compatible acid. Independent claims are also included for the following: (1) oral administration forms comprising a core containing active substance coated with the film coating; and (2) the production of medicament-containing oral administration forms using the film coating.

公开(公告)号：MX2007000962A

公开(公告)日：2007-04-16

申请号：MX2007000962

申请日：2005-08-02

Applicant: BASF AG

Inventor： KOLTER KARL ,  JAHNS EKKEHARD ,  SENGE MICHAEL ,  LANG-WITTKOWSKI GABRIELE ,  SCHMIDT MARCO ,  STEFFEN MARKUS

IPC: B01J13/00 ,  C04B20/10 ,  C09K5/06 ,  F28D20/00

Abstract: La invencion se refiere a una preparacion de microcapsula de particula gruesa que contiene particulas teniendo un tamano de particula de entre 200 mum y 5 cm. Dicha preparacion tambien contiene microcapsulas teniendo un nucleo de capsula que consiste de material acumulador de calor latente, un polimero duroplastico como una pared de capsula, y al menos un agente aglutinante de polimero, el polimero de agente aglutinante del mismo teniendo propiedades termoplasticas ademas de propiedades formadoras de particula bajo condiciones de procesamiento. El agente aglutinante calculado como un solido suma a entre 1 y 30% en peso en relacion con el peso total de la preparacion de microcapsula de particula gruesa.

公开(公告)号：CA2602323A1

公开(公告)日：2006-09-21

申请号：CA2602323

申请日：2006-03-16

Applicant: BASF AG

Inventor： MATHAUER KLEMENS ,  GARCIA CASTRO IVETTE ,  WENDEL VOLKER ,  HOESSEL PETER ,  KOLTER KARL ,  LAUBENDER MATTHIAS ,  JAHNEL WOLFGANG ,  WOOD CLAUDIA

IPC: C08F226/06 ,  A61K8/81 ,  C08F283/06 ,  C08L39/04 ,  C08L51/08

Abstract: The present invention relates to the use of a water-soluble or water-dispersible crosslinked polymer obtainable by the polymerization of a mixture comprising 99.99 to 10% by weight of at least one alpha,beta-ethylenically unsaturated compound having at least one cationogenic and/or cationic group per molecule, 0 to 90% by weight of at least one monoethylenically unsaturated compound containing amide groups which differs from a), and 0.01 to 5% by weight of a crosslinking agent for modifying the rheology of aqueous compositions.

公开(公告)号：CA2515626A1

公开(公告)日：2006-03-15

申请号：CA2515626

申请日：2005-08-10

Applicant: BASF AG

Inventor： WICHTNER MARCUS ,  KOLTER KARL ,  MEYER KATHRIN ,  EINIG HEINZ

IPC: A61K9/20 ,  A61K47/02 ,  A61K47/38

Abstract: A solid oral pharmaceutical dosage form of a sympathomimetic with impede d extractability of the sympathomimetic, comprising I) a sympathomimetic (component I) II) an excipient mixture (component II) composed of a) 5 to 50% by weight of hydroxyalkylcelluloses or alkylcelluloses or mixtur es thereof b) 5 to 70% by weight of xanthan c) 5 to 50% by weight of an alkaline earth metal salt of a C10-C30 fatty aci d d) 10 to 70% by weight of an alkali metal or alkaline earth metal salt of a mineral acid, of a sulfonic acid or of a C2-C6 carboxylic acid or mixtures thereof, where the total of components a) to d) is 100% by weight, where the ratio of active ingredient to excipient mixture II) is from 1:2 to 3:1 by weight.

公开(公告)号：AU2004296546A1

公开(公告)日：2005-06-23

申请号：AU2004296546

申请日：2004-12-09

Applicant: BASF AG

Inventor： KRAMER KLAUS ,  WOOLF HERBERT DENNIS ,  KOLTER KARL

IPC: A21D6/00 ,  A21D13/00 ,  A23B4/10 ,  A23B5/06 ,  A23B7/16 ,  A23G3/34 ,  A23L1/00 ,  A23L3/3454

Abstract: A process for the surface treatment of foods by applying a polymer film, in which, as film-forming polymer, a polyvinyl alcohol-polyether graft copolymer is applied in the form of an aqueous dispersion to the food.

公开(公告)号：DE59712023D1

公开(公告)日：2004-11-25

申请号：DE59712023

申请日：1997-07-24

Applicant: BASF AG

Inventor： LUESSEN HENRIK L ,  BORCHARD GERRIT ,  BOER ALBERTUS G DE ,  JUNGINGER HANS E ,  KOLTER KARL ,  SCHEHLMANN VOLKER ,  SANNER AXEL

IPC: A61K9/00 ,  A61K9/20 ,  A61K31/78 ,  A61K47/30 ,  A61K47/32

Abstract: Pharmaceutical formulation with improved mucous membrane permeability contains (meth)acrylic-maleic acid copolymers (I) for improvement of mucous membrane permeability.

公开(公告)号：DE59711600D1

公开(公告)日：2004-06-09

申请号：DE59711600

申请日：1997-07-21

Applicant: BASF AG

Inventor： KOLTER KARL ,  SUBKOWSKI THOMAS ,  RADITSCH MARTIN ,  SCHEHLMANN VOLKER

IPC: A61K9/02 ,  A61K9/06 ,  A61K9/10 ,  A61K9/107 ,  A61K9/14 ,  A61K9/16 ,  A61K9/20 ,  A61K9/28 ,  A61K31/78 ,  A61K33/24 ,  A61K45/06 ,  A61K47/32

Abstract: (Meth)acrylic acid copolymers are used to increase mucosal permeability, comonomers present being (meth)acrylic esters and/or other monomers capable of free-radical polymerization, and the (meth)acrylic acid:comonomer molar ratio varying from 99:1 to 1:99.

公开(公告)号：DE10211289A1

公开(公告)日：2003-09-25

申请号：DE10211289

申请日：2002-03-14

Applicant: BASF AG

Inventor： KOLTER KARL ,  BODMEIER ROLAND ,  DASHEVSKIY ANDRIY

IPC: A61K9/22 ,  A61K9/32 ,  A61K9/50 ,  C09D133/10

Abstract: The invention relates to the combination of polyvinyl acetate and water-insoluble, acid-insoluble, or alkali-insoluble polymers used for producing film coatings for forms of administration in which agents are released in a controlled manner, and methods for the production thereof. The controlled-release properties can be specifically adjusted by means of said combinations, resulting in films having excellent mechanical stability and storage stability. In particular, agents are released independent of the pH by means of the inventive forms of administration.

公开(公告)号：MXPA03002247A

公开(公告)日：2003-06-24

申请号：MXPA03002247

申请日：2001-10-11

Applicant: BASF AG

Inventor： KOLTER KARL

IPC: C08F8/12 ,  C08F283/06 ,  C11D3/37 ,  C11D17/00 ,  C11D17/04 ,  C11D17/06