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公开(公告)号：KR1020110022411A
公开(公告)日：2011-03-07
申请号：KR1020090079992
申请日：2009-08-27
Applicant: 강릉원주대학교산학협력단
IPC: A61K35/618 , A61K9/14 , A23L33/00
CPC classification number: A61K35/618 , A23L33/00 , A61K9/14
Abstract: PURPOSE: A composition containing Patinopecten yessoensis ingredient is provided to prevent and treat liver diseases due to oxidative stress without side effects or toxicity. CONSTITUTION: A pharmaceutical composition for preventing and treating oxidative stress contains Patinopecten yessoensis ingredient as an active ingredient. The Patinopecten yessoensis ingredient is obtained from dried adductor muscle powder of Patinopecten yessoensis, dried residue powder of Patinopecten yessoensis, adductor muscle extract of Patinopecten yessoensis, or residue extract of Patinopecten yessoensis. The adduct muscle extract of Patinopecten yessoensis is obtained using water including purified water, low alcohol of 1-4 carbon atoms, or mixture solvent thereof. The Patinopecten yessoensis is Patinopecten yessoensis, Pecten albicans, Chlamys farreri, Chlamys swifti, Patinopecten (Mizuhopecten) tokyoensis, or Lima sowerbyi.
Abstract translation: 目的：提供含有Patinopecten yessoensis成分的组合物，用于预防和治疗由于氧化应激引起的肝脏疾病，无副作用或毒性。 构成：用于预防和治疗氧化应激的药物组合物含有作为活性成分的Patinopecten yessoensis成分。 Patinopecten yessoensis成分是从干燥的内收肌肌肉粉，Patinopecten yessoensis的干燥残留粉末，Patinopecten yessoensis的内收肌提取物或Patinopecten yessoensis的残留提取物获得的。 使用包括纯化水，1-4个碳原子的低级醇或其混合溶剂在内的水可得到Pat藜皂甙的加合肌肉提取物。 Patinopecten yessoensis是Patinopecten yessoensis，Pecten albicans，Chlamys farreri，Chlamys swifti，Patinopecten（Mizuhopecten）tokyoensis或Lima sowerbyi。
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公开(公告)号：KR1020110001317A
公开(公告)日：2011-01-06
申请号：KR1020090058800
申请日：2009-06-30
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing fermented Theragra chalcogramma is provided to prevent and treat liver diseases caused by oxidative stress. CONSTITUTION: A pharmaceutical composition for preventing and treating liver diseases caused by oxidative stress contains 0.1-50 weight% of fermented Theragra chalcogramma as an active ingredient. The fermented Theragra chalcogramma is dried powder or extract of fermented Theragra chalcogramma. The extract of fermented Theragra chalcogramma is a polar solvent insoluble extract residue. A health food for preventing and treating liver diseases contains fermented Theragra chalcogramma as an active ingredient. The health food is used in the form of powder, granule, tablet, capsule, syrup or beverage.
Abstract translation: 目的：提供含有发酵的Theragra chalcogramma的组合物，用于预防和治疗由氧化应激引起的肝脏疾病。 构成：用于预防和治疗由氧化应激引起的肝脏疾病的药物组合物含有0.1-50重量％的发酵的Theragra chalcogramma作为活性成分。 发酵的Theragra chalcogramma是发酵的Theragra chalcogramma的干粉或提取物。 发酵的Theragra chalcogramma的提取物是极性溶剂不溶性提取物残留物。 用于预防和治疗肝脏疾病的保健食品含有发酵的Theragra chalcogramma作为活性成分。 保健食品以粉末，颗粒，片剂，胶囊，糖浆或饮料的形式使用。
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公开(公告)号：KR1020110001316A
公开(公告)日：2011-01-06
申请号：KR1020090058799
申请日：2009-06-30
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing fermented flatfish with grains is provided to reduce activity of AST(aspartic acid transaminase), ALT(alanine transaminase), SDH(Sorbitol dehydrogenase), gamma-GT(gamma-glutamyltransferase), ALP(alkaline phosphatase) and LDH(lactate dehydrogenase) and to prevent and treat liver diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating liver diseases caused by oxidative stress contains 0.01-50 weight of fermented flatfish with grains as an active ingredient. The fermented flatfish with grains is a dried powder or extract of fermented flatfish with grains. The extract of fermented flatfish with grains is polar solvent insoluble extract residue. A health food for preventing and treating liver disease caused by oxidative stress contains fermented flatfish with grains as an active ingredient. The health food is used in the form of powder, granule, tablet, capsule, syrup or beverage.
Abstract translation: 目的：提供含有谷物发酵鲽鱼的组合物，以降低AST（天冬氨酸转氨酶），ALT（丙氨酸转氨酶），SDH（山梨醇脱氢酶），γ-GT（γ-谷氨酰转移酶），ALP（碱性磷酸酶）和LDH （乳酸脱氢酶）和预防和治疗肝脏疾病。 构成：用于预防和治疗由氧化应激引起的肝脏疾病的药物组合物含有0.01-50重量的以谷物为活性成分的发酵鲽鱼。 发酵的鲽鱼与谷物是干粉或发酵鲽的提取物与谷物。 发酵鲽鱼提取物为极性溶剂不溶性提取物残渣。 用于预防和治疗由氧化应激引起的肝脏疾病的保健食品包含以谷物为活性成分的发酵鲽鱼。 保健食品以粉末，颗粒，片剂，胶囊，糖浆或饮料的形式使用。
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公开(公告)号：KR1020100137933A
公开(公告)日：2010-12-31
申请号：KR1020090056208
申请日：2009-06-23
Applicant: 강릉원주대학교산학협력단
CPC classification number: A23L17/30 , A23B4/023 , A23V2002/00 , A23V2250/20 , A23V2300/14
Abstract: PURPOSE: A producing method of salted alaska pollack roe using fucoidan is provided to improve the storage property of the salted alaska pollack roe by inserting the fucoidan. CONSTITUTION: A producing method of salted alaska pollack roe using fucoidan comprises the following steps: washing the alaska pollack roe; removing the mixture from the alaska pollack roe and dipping into salt water for fermenting for 1~20hours in 0~10deg C: removing foreign materials from the fermented alaska pollack roe; adding a seasoning solution containing the fucoidan to the alaska pollack roe; and low temperature aging the alaska pollack roe for 24~96hours inside a low temperature aging chamber.
Abstract translation: 目的：提供使用岩藻依聚糖的盐渍阿拉斯加鳕鱼子的生产方法，以通过插入岩藻依聚糖来改善盐渍阿拉斯加鳕鱼卵的储存性能。 构成：使用岩藻依聚糖的盐渍阿拉斯加鳕鱼籽的生产方法包括以下步骤：洗涤阿拉斯加鳕鱼子; 从阿拉斯加鳕鱼卵中取出混合物，浸入盐水中，在0〜10℃下发酵1〜20小时：从发酵的阿拉斯加鳕鱼中除去异物; 将含有岩藻依聚糖的调味溶液加入阿拉斯加鳕鱼子; 并在低温老化室内将阿拉斯加鳕鱼卵的低温老化24〜96小时。
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135.发明授权
公开(公告)号：KR100979888B1
公开(公告)日：2010-09-02
申请号：KR1020080015137
申请日：2008-02-20
Applicant: 강릉원주대학교산학협력단
Abstract: 본 발명은 우렁쉥이 (
Halocynthia
roretzi )의 건조분말 또는 추출물을 유효성분으로 함유하는 당뇨병의 예방 및 치료용 조성물에 관한 것으로, 상세하게는 본 발명의 우렁쉥이의 건조분말 또는 추출물은 스트렙토조토신 (STZ)으로 유발된 당뇨 동물모델의 혈당을 유의적으로 감소시킴으로써 항당뇨 효과를 나타내므로, 상기 조성물은 당뇨병의 예방 및 치료용 약학조성물 또는 건강기능식품으로 유용하게 이용할 수 있다.
우렁쉥이, 당뇨병, 스트렙토조토신-
Patent Agency Ranking136.发明授权
公开(公告)号：KR100974433B1
公开(公告)日：2010-08-05
申请号：KR1020080015135
申请日：2008-02-20
Applicant: 강릉원주대학교산학협력단
IPC: A61K35/616 , A61K9/14 , A23L33/00
Abstract: 본 발명은 해삼 (
Stichpus
japonicus )의 건조분말 또는 추출물을 유효성분으로 함유하는 당뇨병의 예방 및 치료용 조성물에 관한 것으로, 상세하게는 본 발명의 해삼 건조분말 또는 추출물은 스트렙토조토신 (STZ)으로 유발된 당뇨 동물모델의 혈당을 유의적으로 감소시킴으로써 항당뇨 효과를 나타내므로, 상기 조성물은 당뇨병의 예방 및 치료용 약학조성물 또는 건강기능식품으로 유용하게 이용할 수 있다.
해삼, 당뇨병, 스트렙토조토신-
公开(公告)号：KR1020100056142A
公开(公告)日：2010-05-27
申请号：KR1020080115166
申请日：2008-11-19
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition for preventing and treating arteriosclerosis containing Pacific herring fraction dry powder or extract is provided to reduce total cholesterol content in blood. CONSTITUTION: A pharmaceutical composition for preventing and treating arteriosclerosis contains 0.1-50 weight% of Pacific herring fraction dry powder or extract as an active ingredient. The extract is isolated using water, low alcohol of 1-4 carbon atoms, or mixture solvent. A health food for preventing and treating artheriosclerosis contains Pacific herring fraction dry powder or extract as an active ingredient. The health food is used in the form of powder, granule, capsule, or beverage.
Abstract translation: 目的：提供一种用于预防和治疗含有太平洋鲱鱼级干粉或提取物的动脉硬化的组合物，以减少血液中的总胆固醇含量。 构成：用于预防和治疗动脉硬化的药物组合物含有0.1-50重量％的太平洋鲱鱼级干粉或提取物作为活性成分。 使用水，1-4碳原子的低级醇或混合溶剂分离提取物。 用于预防和治疗动物硬化症的保健食品含有太平洋鲱鱼级干粉或提取物作为活性成分。 保健食品以粉末，颗粒，胶囊或饮料的形式使用。
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公开(公告)号：KR1020100056141A
公开(公告)日：2010-05-27
申请号：KR1020080115165
申请日：2008-11-19
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing Pacific herring fraction dry powder or extract is provided to redue neutral fat content in blood and to prevent and treat hyperlipidemia. CONSTITUTION: A pharmaceutical composition for preventing and treating hyperlipidermia contains Pacific herring fraction dry powder or extract as an active ingredient. The Pacific herring fraction is obtained from total body of the Pacific herring, muscle, intestine, head, bone, cartilage, skin, eye, and gill. The Pacific herring fraction is isolated using water, low alcohol of 1-4 carton atoms, or mixture solvent.
Abstract translation: 目的：提供含有太平洋鲱鱼级干粉或提取物的组合物，以减少血液中的中性脂肪含量并预防和治疗高脂血症。 构成：用于预防和治疗高脂血症的药物组合物含有太平洋鲱鱼级干粉或提取物作为活性成分。 太平洋鲱鱼分数是从太平洋鲱鱼，肌肉，肠，头，骨，软骨，皮肤，眼睛和鳃的全身获得的。 太平洋鲱鱼分数使用水，1-4巴原子的低醇或混合溶剂分离。
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139.发明公开꽁치 분획 건조 분말 또는 그 추출물을 유효성분으로함유하는 산화 관련 질환의 예방 및 치료용 조성물 无效包含干粉（COLOABIS SAIRA）分类的组合物或其用于预防和治疗氧化相关疾病的提取物
公开(公告)号：KR1020100006895A
公开(公告)日：2010-01-22
申请号：KR1020080067216
申请日：2008-07-10
Applicant: 강릉원주대학교산학협력단
Abstract: PURPOSE: A composition containing pacific saury-dried fraction or its extract is provided to reduce oxygen free radical and malodialdehyde(MDA) and ensure SOD(superoxide dismutase) activity. CONSTITUTION: A pharmaceutical composition for preventing and treating oxidation-related diseases contains pacific saury fraction dried powder or its extract as an active ingredient. The pacific saury fraction dried powder is obtained by: washing the pacific saury, removing foreign material and salt; cutting the pacific saury to intestines, whole body, bone, cartilage, skin, muscle, eye and gills; and performing vacuum-drying or light drying of the fractions. The extract of the pacific saury fraction is obtained by grinding or pulverizing the fractions and extracting with water, alcohol or spirit. The oxidation-related diseases is cancer, diabetes, hepatitis, gastritis, nephritis, carditis, rheumatoid arthritis, heart disease, AIDS, cataract or dermatome.
Abstract translation: 目的：提供含有太平洋西番莲干组分或其提取物的组合物，以减少氧自由基和malodialdehyde（MDA），并确保SOD（超氧化物歧化酶）活性。 构成：用于预防和治疗氧化相关疾病的药物组合物含有太平洋刀屑级干粉或其提取物作为活性成分。 太平洋切碎干粉是通过以下方法获得的：洗涤太平洋刀，去除异物和盐; 切割太平洋刀对肠，全身，骨，软骨，皮肤，肌肉，眼睛和鳃; 并对该级分进行真空干燥或轻度干燥。 通过研磨或粉碎级分并用水，酒精或精油提取，可获得太平洋刀鱼馏分的提取物。 氧化相关疾病是癌症，糖尿病，肝炎，胃炎，肾炎，心脏炎，类风湿性关节炎，心脏病，艾滋病，白内障或皮肤病。
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公开(公告)号：KR1020090123162A
公开(公告)日：2009-12-02
申请号：KR1020080049104
申请日：2008-05-27
Applicant: 강릉원주대학교산학협력단
IPC: C12P23/00
Abstract: PURPOSE: A method for culturing zeaxanthin producing strain is provided to massively zeaxanthin with high yield from marine biomass regardless of season. CONSTITUTION: A method for culturing zeaxanthin producing strain comprises: a first step of isolating strain having productivity of zeaxanthin; a second step of sub-culturing isolated strain; a third step of measuring productivity of zeaxanthin; and a step of adding medium at 1~50°C and 10~300 rpm then culturing. The strain having productivity of zeaxanthin is Micrococcus luteus, Vibrio, Pseudomonas, Achromobacter, Aeromonas, Photobacterium, Acetobacter, Gluconobacter, Alcaligenes, or Flavobacterium.
Abstract translation: 目的：提供玉米黄质生产菌株的培养方法，无论季节如何，都可以大量生产来自海洋生物质的玉米黄质。 构成：培养玉米黄质生产菌株的方法包括：分离具有玉米黄质生产力的菌株的第一步骤; 亚培养分离菌株的第二步; 测量玉米黄质生产力的第三步; 并在1〜50℃，10〜300rpm下加入培养基，然后培养。 具有玉米黄质生产力的菌株是藤黄微球菌，弧菌属，假单胞菌属，无色杆菌属，气单胞菌属，光杆菌属，醋杆菌属，葡糖杆菌属，产碱杆菌属或黄杆菌属。
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