公开(公告)号：SI0930875T1

公开(公告)日：2003-10-31

申请号：SI9730566

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JOERG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61K9/20 ,  A61K9/22

公开(公告)号：DE59710059D1

公开(公告)日：2003-06-12

申请号：DE59710059

申请日：1997-09-11

Applicant: BASF AG

Inventor： BREITENBACH JOERG ,  KLEINKE ANDREAS ,  KOTHRADE STEPHAN ,  ROSENBERG JOERG

IPC: A61J3/00 ,  A61K9/16 ,  A61K9/20 ,  A61K9/22

Abstract: A process for producing solid dose forms by mixing at least one polymeric binder, with or without at least one active ingredient and with or without conventional additives, and shaping the mixture, where at least one of the components is employed in liquid form.

公开(公告)号：DE59609923D1

公开(公告)日：2003-01-09

申请号：DE59609923

申请日：1996-09-30

Applicant: BASF AG

Inventor： ZEIDLER JUERGEN ,  ROSENBERG JOERG ,  NEUMANN JOERG ,  BREITENBACH JOERG

IPC: A61K9/16 ,  A61K9/20 ,  A61K31/277 ,  A61K47/24 ,  A61K47/26 ,  A61K47/30

Abstract: The invention relates to solid drug forms obtainable by extrusion with subsequent shaping of a solvent-free melt, comprising, besides one or more active ingredients,A) 10-90% by weight of a melt-processable, water-soluble polymer,B) 5-85% by weight of isomalt, andC) 0-5% by weight of lecithin,where the total of all the ingredients is to be equal to 100% by weight.

公开(公告)号：DK0854707T3

公开(公告)日：2002-12-16

申请号：DK96934494

申请日：1996-09-30

Applicant: BASF AG

Inventor： ZEIDLER JUERGEN ,  ROSENBERG JOERG ,  NEUMANN JOERG ,  BREITENBACH JOERG

IPC: A61K9/16 ,  A61K9/20 ,  A61K31/277 ,  A61K47/24 ,  A61K47/26 ,  A61K47/30

Abstract: The invention relates to solid drug forms obtainable by extrusion with subsequent shaping of a solvent-free melt, comprising, besides one or more active ingredients,A) 10-90% by weight of a melt-processable, water-soluble polymer,B) 5-85% by weight of isomalt, andC) 0-5% by weight of lecithin,where the total of all the ingredients is to be equal to 100% by weight.

公开(公告)号：PT809488E

公开(公告)日：2002-11-29

申请号：PT96903958

申请日：1996-02-01

Applicant: BASF AG

Inventor： GRABOWSKI SVEN ,  AXEL SANNER DR ,  ROSENBERG JOERG ,  BREITENBACH JORG

IPC: A61K9/22 ,  A61K9/20

Abstract: PCT No. PCT/EP96/00417 Sec. 371 Date Jul. 30, 1997 Sec. 102(e) Date Jul. 30, 1997 PCT Filed Feb. 1, 1996 PCT Pub. No. WO96/25151 PCT Pub. Date Aug. 22, 1996Solid preparations are obtainable by melt extrusion of A) at least one active compound, B) a mixture of B1) from 10 to 90% by weight of a water-soluble, thermoplastic polymer, and B2) from 10 to 90% by weight of a low-substituted hydroxypropylcellulose, and C) from 0 to 50% by weight, based on the total amount of the preparation, of customary pharmaceutical auxiliaries.

公开(公告)号：HU221614B

公开(公告)日：2002-11-28

申请号：HU9801152

申请日：1996-03-09

Applicant: BASF AG

Inventor： BREITENBACH JOERG ,  ROSENBERG JOERG ,  SANNER AXEL

IPC: A61K9/00 ,  A61K9/20 ,  A61K31/19 ,  A61K31/192 ,  A61K47/30

Abstract: PCT No. PCT/EP96/01021 Sec. 371 Date Sep. 16, 1997 Sec. 102(e) Date Sep. 16, 1997 PCT Filed Mar. 9, 1996 PCT Pub. No. WO96/29053 PCT Pub. Date Sep. 26, 1996Transparent rapid release active substance compositions obtainable by extrusion of melts, containing non-steroidal analgesics, homopolymers of N-vinylpyrrolidone, saccharides or sugar alcohols and sodium or potassium salts.

公开(公告)号：EA002853B1

公开(公告)日：2002-10-31

申请号：EA200000132

申请日：1998-07-21

Applicant: BASF AG

Inventor： ZEIDER JURGEN ,  NEUMANN JORG ,  LIEPOLD BERND ,  ROSENBERG JOERG ,  BERNDL GUNTHER ,  BREITENBACH JORG ,  VOLLGRAF CHRISTIANE

IPC: A61K9/20 ,  A61K31/192 ,  A61K47/02 ,  A61K47/32 ,  A61P29/00 ,  A61P29/02

Abstract: Настоящееизобретениеотноситсяк быстродействующемуобезболивающемупрепарату, содержащемув качествеобезболивающеговеществаибупрофенв матрицевспомогательныхвеществи имеющемупористуюструктуруи плотностьотболее 1 г/смидо 2,5 г/см. Изобретениетакжеотноситсяк способуполучениятакогопрепарата.

公开(公告)号：DK0809488T3

公开(公告)日：2002-09-02

申请号：DK96903958

申请日：1996-02-01

Applicant: BASF AG

Inventor： SANNER AXEL ,  ROSENBERG JOERG ,  GRABOWSKI SVEN ,  BREITENBACH JOERG

IPC: A61K9/22 ,  A61K9/20

Abstract: PCT No. PCT/EP96/00417 Sec. 371 Date Jul. 30, 1997 Sec. 102(e) Date Jul. 30, 1997 PCT Filed Feb. 1, 1996 PCT Pub. No. WO96/25151 PCT Pub. Date Aug. 22, 1996Solid preparations are obtainable by melt extrusion of A) at least one active compound, B) a mixture of B1) from 10 to 90% by weight of a water-soluble, thermoplastic polymer, and B2) from 10 to 90% by weight of a low-substituted hydroxypropylcellulose, and C) from 0 to 50% by weight, based on the total amount of the preparation, of customary pharmaceutical auxiliaries.

公开(公告)号：AT220541T

公开(公告)日：2002-08-15

申请号：AT96903958

申请日：1996-02-01

Applicant: BASF AG

Inventor： GRABOWSKI SVEN ,  BREITENBACH JOERG ,  ROSENBERG JOERG ,  SANNER AXEL

IPC: A61K9/22 ,  A61K9/20

Abstract: PCT No. PCT/EP96/00417 Sec. 371 Date Jul. 30, 1997 Sec. 102(e) Date Jul. 30, 1997 PCT Filed Feb. 1, 1996 PCT Pub. No. WO96/25151 PCT Pub. Date Aug. 22, 1996Solid preparations are obtainable by melt extrusion of A) at least one active compound, B) a mixture of B1) from 10 to 90% by weight of a water-soluble, thermoplastic polymer, and B2) from 10 to 90% by weight of a low-substituted hydroxypropylcellulose, and C) from 0 to 50% by weight, based on the total amount of the preparation, of customary pharmaceutical auxiliaries.

公开(公告)号：ES2170259T3

公开(公告)日：2002-08-01

申请号：ES96929292

申请日：1996-08-21

Applicant: BASF AG

Inventor： ROSENBERG JOERG ,  BREITENBACH JORG

IPC: A61K9/20

Abstract: Lipids are used as aids in the production of solid drug forms by melt extrusion.