Abstract:
PURPOSE: A natural edible antimicrobial agent for food using the composite nanonization of a Japanese horseradish extract, and a producing method thereof are provided to reduce the unique smell of Japanese horseradish, and to maintain the quality of the food. CONSTITUTION: A producing method of a natural edible antimicrobial agent for food using the composite nanonization of a Japanese horseradish extract comprises the following steps: crushing Japanese horseradish, mixing the crushed Japanese horseradish with distilled water, tween-20, and homogenizing the mixture in a homogenizer; passing the obtained Japanese horseradish fluid through a micro-tube in the high pressure of 20,000-30,000psi for homogenizing the Japanese horseradish into the nano size; repeating the homogenizing process for 1-10 times; mixing and dissolving lecithin in a container with chloroform, and removing the chloroform using a decompressor to obtain multi-layers of the lecithin; inserting the Japanese horseradish fluid into the container with the multi-layers; and dispersing the Japanese horseradish fluid using ultrasonic waves for 30-40 minutes. [Reference numerals] (AA) Conventional single nanonization process; (BB) New complex nanonization process; (CC) Microfluidizer process: Japanese horseradish nanoparticles with the coagulating particles and Japanese horseradish smell; (DD) Homogenizer process: emulsified and homogenized Japanese horseradish samples; (EE) Ultrasonic dispersion process: Japanese horseradish nanoparticles with low collection rate, and unstable to the external environment; (FF) Microfluidizer process: homogenizing the Japanese horseradish nanoparticles; (GG) Japanese horseradish nanoparticles with low collection rate, and unstable to the external environment; (HH) Collecting the Japanese horseradish samples with lecithin for reducing the smell; (II) Japanese horseradish nanoparticles with high uniformity and collection rate, without the smell
Abstract:
본 발명은 고로쇠나무의 이단 복합 추출방법 및 그 추출물에 관한 것으로, 고로쇠나무로부터 생리활성물질을 효율적으로 뽑아내기 위해 고로쇠나무 수피를 대상으로 마이크로웨이브 추출과 저온 고압 추출의 이단 복합 추출을 순차적으로 행하는 것을 특징으로 한다. 상기 본 발명에 따를 경우, 추출물의 독성 감소와 함께 일반적인 추출 공정에서는 용출되지 않았던 다양한 생리활성성분의 용출을 유도할 수 있어 다양한 생리활성 증진 효과를 얻을 수 있다.
Abstract:
본발명은서열번호 7 및 8의프라이머쌍, 서열번호 13 및 14의프라이머쌍, 서열번호 31 및 32의프라이머쌍 그리고서열번호 33 및 34의프라이머쌍으로구성된군으로부터선택된하나이상의프라이머쌍; 서열번호 53 및 54의프라이머쌍, 서열번호 89 및 90의프라이머쌍, 그리고서열번호 91 및 92의프라이머쌍으로구성된군으로부터선택된하나이상의프라이머쌍; 및/또는서열번호 127 및 128의프라이머쌍을포함하는다중항생제내성황색포도상구균, 다중항생제내성폐렴막대균및/또는살모넬라티피무리움검출용키트및 그것을이용한검출방법에관한것이다. 본발명의프라이머쌍은이들다중항생제내성균주를검출하는데유용하게사용할수 있다.
Abstract:
PURPOSE: A producing method of a codonopsis lanceolata extract using extra-high pressure is provided to optimize the extraction efficiency for the effective components of codonopsis lanceolata. CONSTITUTION: A producing method of a codonopsis lanceolata extract using extra-high pressure comprises a step of low temperature-extra high pressure treating codonopsis lanceolata at 25-35 deg C at a pressure of 200-500MPa for 20-30 minutes to extract effective components from the codonopsis lanceolata. The treating process uses water as a solvent for mixing with the codonopsis lanceolata and vacuum packaging. The effective components in the codonopsis lanceolata include flavonoids, vanilic acid, p-hydroxybenzoic acid, p-coumaric acid, and other compounds.
Abstract:
PURPOSE: A composition containing Sophora flavescens Aiton extract for preventing and treating dermatitis is provided to suppress propionibacterium acne. CONSTITUTION: A composition for preventing and treating dermatitis contains Sophora flavescens Aiton extract as an active ingredient. The daily dose of the extract is 10-5000mg a day. The composition is manufactured in the form of a solution, suspension, emulsion, paste, gel, cream, soap, surfactant-containing cleansing, oil, powder foundation, emulsion foundation, wax foundation, or spray.
Abstract:
본 발명은 젤라틴(gelatin)에 포집된 수용성 매자나무( Berberis
Koreana ) 추출물을 포함하는 나노입자(nano-particles), 그 제조 방법 및 이를 사용하여 수용성 매자나무 추출물의 세포 내 용출 속도를 조정하여 세포 독성(cytotoxicity)을 저감시키는 방법에 관한 것이다. 본 발명의 나노입자, 그 제조 방법 및 이를 이용한 세포 독성 저감 방법은, 수용성 매자나무 추출물을 신경세포 보호 및 비만·당뇨의 억제제 등의 기능성 소재로 활용하는 경우에 매자나무가 고유하게 가지는 세포 독성을 저감하기 위해 생체 내에서의 방출속도 및 농도를 일정하게 조절함과 동시에 적은 농도로 높은 생리활성의 발현이 가능한 우수한 효과가 있다. 나노입자, 매자나무, 비만, 당뇨, 젤라틴, 세포 독성
Abstract:
PURPOSE: A method for producing a nanoparticle containing water-soluble Korean barberry extract is provided to release the extract in a specific rate and control cytotoxicty. CONSTITUTION: A method for producing a nanoparticle containing water-soluble Korean barberry extract with high density of gelatin comprises: a step of extracting Korean barberry, filtering, concentrating, and drying to obtain powder; a step of dissolving the powder in water-soluble solvent; a step of dissolving 0.05-0.2 weight% of gelatin of the extract using distilled water at 40°C; a step of drying at 20~60°C to obtain liposomes; a step of adding Korean barberry extract to the gelatin of liposome form; and a step of homogenizing at 30~40°C for 50-60 minutes with sonicator.
Abstract:
본발명은비쭈기나무, 등대풀, 찔레, 말오줌때, 서어나무, 및왕달맞이꽃추출물로구성된군으로부터선택된하나이상의추출물을유효성분으로포함하는베타-락타메이즈저해용조성물, 및비쭈기나무, 등대풀, 찔레, 말오줌때, 서어나무, 및왕달맞이꽃추출물로구성된군으로부터선택된하나이상의추출물과베타-락탐계항생제를유효성분으로포함하는 Staphylococcus aureus에대한항균용조성물에관한것이다.본발명의천연추출물이페니실린계열인 piperacillin의항균효과를증가시키는새로운보조제로서사용될수 있으며, β-lactam ring 분해효소인β-lactamase을억제할수 있는 inhibitor로서미생물의내성기전저해에사용될수 있다. 본발명의천연추출물이페니실린계열인 piperacillin의항균효과를증가시키는새로운보조제로서사용될수 있으며, β-lactam ring 분해효소인β-lactamase을억제할수 있는 inhibitor로서미생물의내성기전저해에사용될수 있다.