公开(公告)号：DE19617716A1

公开(公告)日：1997-11-06

申请号：DE19617716

申请日：1996-05-03

Applicant: BASF AG

Inventor： BREITENBACH JOERG DR ,  KOLTER KARL DR ,  SCHMITT ANGELIKA ,  TIEFENSEE KRISTIN DR ,  SCHEHLMANN VOLKER DR

IPC: A61K8/81 ,  A61K9/28 ,  A61K47/32 ,  A61Q1/12 ,  C08J3/03 ,  C08L31/00 ,  C08L33/08 ,  C08J3/12 ,  C08L33/10 ,  A61K7/48

Abstract: Polymer powders redispersible in aqueous solution, their use in cosmetic, pharmaceutical or plant-protection preparations and a process for producing polymer powders redispersible in aqueous solution, containing free acid or basic group-bearing copolymers and possibly auxiliaries, in which the pH of the dispersion is adjusted by the addition of at least one buffer system before drying at 2.0 to 6.5 in the case of acid group-bearing copolymers and at 7.5 to 12 in the case of basic group-bearing copolymers.

公开(公告)号：DE19641345A1

公开(公告)日：1997-04-24

申请号：DE19641345

申请日：1996-10-08

Applicant: BASF AG

Inventor： FISCH HERBERT DR ,  BREITENBACH JOERG DR ,  SCHLARB BERNHARD DR ,  PIPPER GUNTER

IPC: C08G69/36 ,  C09D177/00 ,  D06N3/12 ,  D06N7/00 ,  C08G69/08 ,  C08G69/42

Abstract: Use of aq. dispersions of water-dispersible polyamides containing as component 1-7 mol-% of a dicarboxylic acid with sulphonate groups as coating compositions is claimed. Also claimed are: (i) coated articles obtd. by use of the aq. dispersions; and (ii) carpets with a back coating, obtained by use of the aqueous dispersions.

公开(公告)号：DE19539361A1

公开(公告)日：1997-04-24

申请号：DE19539361

申请日：1995-10-23

Applicant: BASF AG

Inventor： BREITENBACH JOERG DR ,  HAERTL AXEL PAUL DR ,  HOFMANN JUERGEN ,  ROSENBERG JOERG DR ,  SCHIESL MICHAEL ,  ZETTLER HANS DIETER

IPC: A61J3/10 ,  A61K9/20 ,  A61K9/24 ,  A61K9/28 ,  A61K31/07 ,  A61K31/167 ,  A61K31/192 ,  A61K31/277 ,  A61K31/355 ,  A61K31/375 ,  A61K31/401 ,  A61K31/4422 ,  A61K31/52 ,  A61K31/522 ,  A61K31/60 ,  A61K31/19

Abstract: The invention concerns a method of producing multi-layer medicaments in solid form for oral or rectal administration. At least two substances, which each comprise a thermoplastic, pharmacologically acceptable polymer binder which is soluble or can swell in a physiological environment, at least one of the substances comprising a pharmaceutical active substance, are coextruded and the coextruded multi-layer material is shaped to form the desired medicament.

公开(公告)号：DE19509807A1

公开(公告)日：1996-09-26

申请号：DE19509807

申请日：1995-03-21

Applicant: BASF AG

Inventor： ROSENBERG JOERG DR ,  BREITENBACH JOERG DR

IPC: A61K9/14 ,  A61K9/20 ,  B01J2/20 ,  A61K31/60 ,  A61K31/485

Abstract: A process for producing active agent preparations in the form of a solid solution of the active agent in a polymer matrix in which the active agent is melt-extruded in non-ionic form together with a polymer and a salt.

公开(公告)号：DE19509805A1

公开(公告)日：1996-09-26

申请号：DE19509805

申请日：1995-03-21

Applicant: BASF AG

Inventor： BREITENBACH JOERG DR ,  ROSENBERG JOERG DR ,  SANNER AXEL DR

IPC: A61K9/00 ,  A61K9/20 ,  A61K31/19 ,  A61K31/192 ,  A61K47/30 ,  A61K31/445

Abstract: Transparent rapid-release active agent preparations obtainable by the extrusion of melts containing non-steroid analgesics, homopolymers of N-vinyl pyrrolidone, saccharides or sugar alcohols and sodium or potassium salts.

公开(公告)号：DE4446468A1

公开(公告)日：1996-06-27

申请号：DE4446468

申请日：1994-12-23

Applicant: BASF AG

Inventor： ROSENBERG JOERG DR ,  MAIER WERNER ,  GRABOWSKI SVEN DR ,  BREITENBACH JOERG DR

IPC: A61J1/03 ,  A61J3/00 ,  A61J3/10 ,  A61K9/20 ,  A61K9/28 ,  B30B11/16 ,  B65B9/04

Abstract: The invention concerns a method of producing coated tablets by melt calendering, the melt containing the active substance being introduced into the form cylinders between two films of the coating material.

公开(公告)号：DE4442900A1

公开(公告)日：1996-06-05

申请号：DE4442900

申请日：1994-12-02

Applicant: BASF AG

Inventor： BREITENBACH JOERG DR ,  SANNER AXEL DR

IPC: C08F6/00 ,  C08F8/00 ,  C08K3/20 ,  C08L39/04 ,  C01B15/037 ,  C08F26/06 ,  C08F26/10

公开(公告)号：DE19733504A1

公开(公告)日：1999-02-04

申请号：DE19733504

申请日：1997-08-01

Applicant: BASF AG

Inventor： BERNDL GUNTHER DR ,  BREITENBACH JOERG DR

IPC: A23K40/10 ,  A23K40/20 ,  A23K50/80 ,  A23K1/18 ,  A23K1/16 ,  A23P1/12 ,  A23P1/02

Abstract: The invention relates to slow sinking, porous granules or pellets with a density of greater than 1 g/cm for use in fish breeding. The inventive granules or pellets are obtained by solvent-free melt extrusion of mixtures consisting of biologically active substances, matrix support substances and a solid gas producer.

公开(公告)号：DE19721467A1

公开(公告)日：1998-11-26

申请号：DE19721467

申请日：1997-05-22

Applicant: BASF AG

Inventor： BREITENBACH JOERG DR ,  ZETTLER HANS DIETER

IPC: A61K9/16 ,  B01J2/20 ,  B29C47/00 ,  B29C47/40 ,  B29C47/78 ,  B29C48/395 ,  B29C48/67 ,  A61K9/26 ,  A61K31/165 ,  A61K31/23 ,  A61K31/52

Abstract: The invention relates to a method for the continuous production of solid, particle-based preparations of biologically active substances, in which preparations the biologically active substances are homogeneously distributed in a matrix of additives which can be thermoplastically processed, in a screw extruder divided into several zones. Said method is characterized in that the matrix additives are first melted in a heatable area and the biologically active components mixed with the matrix additives. Thereafter, the mixture is cooled, pre-crushed and finely ground in a cooling zone. The screw geometry of the cooling zone is designed in such a way that the cooling zone comprises a conveyor zone, a mixing zone and a kneading zone.

公开(公告)号：DE19624607A1

公开(公告)日：1998-01-02

申请号：DE19624607

申请日：1996-06-20

Applicant: BASF AG

Inventor： BREITENBACH JOERG DR ,  ROSENBERG JOERG DR ,  NEUMANN JOERG DR ,  ZEIDLER JUERGEN DR ,  SIMON DIRK DR ,  DIENER RALPH DR

IPC: A61K31/19 ,  A61K9/16 ,  A61K31/00 ,  B01J19/00 ,  C07C51/41 ,  C07C57/30 ,  C07C229/26 ,  A61K31/195

Abstract: Preparation of a salt of a pharmaceutically active carboxylic acid compound comprises reacting the acid in an extruder with ≥ 1 stoichiometric equivalent of a base in melt form.