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公开(公告)号:DE19731274A1
公开(公告)日:1999-01-28
申请号:DE19731274
申请日:1997-07-22
Applicant: BASF AG
Inventor: SCHROEDER HARTWIG DR , HAUER BERNHARD DR
IPC: C12N15/09 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/10 , C12N15/12 , C12N15/52 , C12N15/54 , C12P17/18 , C12N15/63 , C12N15/70 , C12N15/74 , C12N15/81 , C12N1/00 , C07D495/04
Abstract: The invention relates to a gene construct containing a biotin gene with the sequence SEQ ID No. 1 or SEQ ID No. 3, and to organisms containing said gene construct, the use of these sequences or the gene construct for producing biotin and to a method for producing biotin.
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公开(公告)号:DE19623608A1
公开(公告)日:1997-12-18
申请号:DE19623608
申请日:1996-06-13
Applicant: BASF AG
Inventor: MUELLER ULRICH DR , GROSCH GEORG HEINRICH DR , HAUER BERNHARD DR , SCHULZ MICHAEL DR , RIEBER NORBERT DR
IPC: B01J29/04 , B01J29/89 , C07D301/12 , C07D301/19 , C07D303/04
Abstract: A process for producing epoxides from olefines and hydrogen peroxide or hydroperoxides in the liquid phase using an oxidation catalyst based on titanium or vanadium silicalites with a zeolithic structure, in which the concentration of the hydrogen peroxide or hydroperoxides in the reaction mixture is in the range from 0.05 to less than 1 wt.% during the reaction.
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公开(公告)号:GR3023791T3
公开(公告)日:1997-09-30
申请号:GR970401431
申请日:1997-06-18
Applicant: BASF AG
Inventor: STAUDENMAIER HORST RALF DR , HAUER BERNHARD DR , BALKENHOHL FRIEDHELM DR , LADNER WOLFGANG DR , SCHNELL URSULA DR , PRESSLER UWE DR
Abstract: Prodn. of enantiomeric lactams of formula (I) comprises reacting a racemate (I) with a biocatalyst which reacts with one enantiomer and isolating the unreacted enantiomer from the mixt. obtd. R1, R2 = 1-4C alkyl, 2-4C alkenyl or aryl (all opt. substd.), H or (CH2)n-COOH; n = 0-3; x = 1-5. Pref. the biocatalyst is a microorganism, esp. from Pseudomonas or Rhodococcus.
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公开(公告)号:DE19736104A1
公开(公告)日:1999-02-25
申请号:DE19736104
申请日:1997-08-20
Applicant: BASF AG
Inventor: BREUER MICHAEL DR , HAUER BERNHARD DR , MESCH KATHRIN , IDING HANS , GOETZ GUENTER , POHL MARTINA DR , KULA MARIA-REGINA PROF DR
IPC: C12N9/88 , C12P7/26 , C07C45/72 , C07C49/245
Abstract: Preparation of entantiomerically pure phenylacetycarbinol derivatives (I) from acetaldehyde and benzaldehyde is carried out in the presence of pyruvate decarboxylase, which is obtained from Zymomonas mobilis. Preparation of entantiomerically pure phenylacetycarbinol derivatives of formula (I) comprises reacting acetaldehyde with the corresponding benzaldehyde (II) in the presence of pyruvate decarboxylase obtained from Zymomonas. The novelty comprises continuous or discontinuous addition of acetaldehyde to the reaction mixture, to ensure that the acetaldehyde concentration stays at 20-50 mMol/l: R = H, F, Cl or Br.
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公开(公告)号:ES2100759T3
公开(公告)日:1997-06-16
申请号:ES95108695
申请日:1995-06-07
Applicant: BASF AG
Inventor: STAUDENMAIER HORST RALF DR , HAUER BERNHARD DR , BALKENHOHL FRIEDHELM DR , LADNER WOLFGANG DR , SCHNELL URSULA DR , PRESSLER UWE DR
Abstract: Prodn. of enantiomeric lactams of formula (I) comprises reacting a racemate (I) with a biocatalyst which reacts with one enantiomer and isolating the unreacted enantiomer from the mixt. obtd. R1, R2 = 1-4C alkyl, 2-4C alkenyl or aryl (all opt. substd.), H or (CH2)n-COOH; n = 0-3; x = 1-5. Pref. the biocatalyst is a microorganism, esp. from Pseudomonas or Rhodococcus.
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公开(公告)号:DE59500222D1
公开(公告)日:1997-06-12
申请号:DE59500222
申请日:1995-06-07
Applicant: BASF AG
Inventor: STAUDENMAIER HORST RALF DR , HAUER BERNHARD DR , BALKENHOHL FRIEDHELM DR , LADNER WOLFGANG DR , SCHNELL URSULA DR , PRESSLER UWE DR
Abstract: Prodn. of enantiomeric lactams of formula (I) comprises reacting a racemate (I) with a biocatalyst which reacts with one enantiomer and isolating the unreacted enantiomer from the mixt. obtd. R1, R2 = 1-4C alkyl, 2-4C alkenyl or aryl (all opt. substd.), H or (CH2)n-COOH; n = 0-3; x = 1-5. Pref. the biocatalyst is a microorganism, esp. from Pseudomonas or Rhodococcus.
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公开(公告)号:DE4344211A1
公开(公告)日:1995-06-29
申请号:DE4344211
申请日:1993-12-23
Applicant: BASF AG
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公开(公告)号:DE4238905A1
公开(公告)日:1994-05-26
申请号:DE4238905
申请日:1992-11-19
Applicant: BASF AG
Inventor: MEYER JOACHIM DR , HAUER BERNHARD DR
IPC: C07C59/215 , C12P7/58
Abstract: Prepn. of 2,5-diketo-gluconic acid (2,5-DGA) comprises fermentive oxidn. in the presence of oxygen by (a) synthesising 2,5-DGA from glucose in a main reactor and by (b) further oxidn. of (a) to form more 2,5-DGA in a subsequent reactor without the addn. of fresh glucose until no substantial quantities of 2-keto-D-gulonic acid and/or gluconic acid are present in the end prod.. Pref. the continuous fermentive oxidn. is with Erwinia in a main reactor contg. 100 to 400g glucose/l. The pref. exchange rate is 0.05 to 0.5 litre and hour more pref. 0.1 to 0.2 litre an hour. USE/ADVANTAGE - 2,5-DGA is a precursor of 2-keto-L-gulonic acid which can be rearranged to form ascorbic acid. Currently, only batch processes have been described for the formation of 2,5-DGA. The new method is a continuous process that is faster and needs less space than known methods, and a pure prod. can be produced. In contrast to prior art methods, with a reactor in series (b), the side prod. formation of gluconic acids and 2-keto-D-gluconic acid can be avoided.
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公开(公告)号:DE3910024A1
公开(公告)日:1990-10-11
申请号:DE3910024
申请日:1989-03-28
Applicant: BASF AG
Inventor: COOPER BRYAN DR , LADNER WOLFGANG DR , HAUER BERNHARD DR , SIEGEL HARDO DR
IPC: C12P7/42 , C12P7/52 , C12R1/465 , C12R1/48 , C12R1/55 , C12R1/645 , C12R1/66 , C12R1/685 , C12R1/79
Abstract: Process for oxidizing 2-(phenoxy-)propionic acid to 2-(4-hydroxyphenoxy-)propionic acid using microorganisms.
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