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公开(公告)号：BR9810851A
公开(公告)日：2000-07-25
申请号：BR9810851
申请日：1998-07-21
Applicant: BASF AG
Inventor： ZEIDLER JUERGEN , NEUMANN JOERG , LIEPOLD BERND , ROSENBERG JOERG , BERNDL GUNTHER , BREITENBACH JOERG , VOLLGRAF CHRISTIANE
Abstract: A fast-acting analgesic comprises as analgesic substance ibuprofen in an adjuvant matrix with a porous structure and a density of greater than 1 and up to 2.5 g/cm3.
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公开(公告)号：CA2298659A1
公开(公告)日：1999-02-11
申请号：CA2298659
申请日：1998-07-21
Applicant: BASF AG
Inventor： ZEIDLER JURGEN , ROSENBERG JORG , BREITENBACH JORG , BERNDL GUNTHER , VOLLGRAF CHRISTIANE , NEUMANN JORG , LIEPOLD BERND
Abstract: The invention relates to a fast-acting analgesic, containing ibuprofen as the active analgesic substance in an auxiliary substance matrix, with a porous structure and a density of greater than 1 - 2.5 g/cm3.
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公开(公告)号：BRPI0009299B8
公开(公告)日：2021-07-06
申请号：BRPI0009299
申请日：2000-03-17
Applicant: BASF AG
Inventor： ROSENBERG JOERG , BERNDL GUNTHER , LIEPOLD BERND , BREITENBACH JOERG
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公开(公告)号：CA2368138C
公开(公告)日：2006-08-22
申请号：CA2368138
申请日：2000-03-17
Applicant: BASF AG
Inventor： ROSENBERG JORG , LIEPOLD BERND , BERNDL GUNTHER , BREITENBACH JORG
IPC: A61K9/20 , A61K47/10 , A61K9/16 , A61K47/14 , A61K47/34 , A61P31/10 , A61P35/00 , A61P37/06 , A61P43/00
Abstract: The invention relates to mechanically stable pharmaceutical presentation for ms for peroral administration which in addition to one or more active ingredien ts and at least one thermoplastically mouldable matrix-forming auxiliary contai n more than 10 and up to 40 % by weight of a surface-active substance which ha s an HLB of between 2 and 18 and is liquid at 20 ~C or has a dropping point at between 20 and 50 ~C.
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公开(公告)号：AU748772B2
公开(公告)日：2002-06-13
申请号：AU8632298
申请日：1998-07-21
Applicant: BASF AG
Inventor： ZEIDLER JUERGEN , NEUMANN JOERG , LIEPOLD BERND , ROSENBERG JOERG , BERNDL GUNTHER , BREITENBACH JOERG , VOLLGRAF CHRISTIANE
Abstract: A fast-acting analgesic comprises as analgesic substance ibuprofen in an adjuvant matrix with a porous structure and a density of greater than 1 and up to 2.5 g/cm3.
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Patent Agency Ranking
公开(公告)号：BRPI0009299A
公开(公告)日：2001-12-18
申请号：BRPI0009299
申请日：2000-03-17
Applicant: BASF AG
Inventor： ROSENBERG JOERG , BERNDL GUNTHER , LIEPOLD BERND , BREITENBACH JOERG
IPC: A61K9/16 , A61K47/10 , A61K9/20 , A61K47/14 , A61K47/34 , A61P31/10 , A61P35/00 , A61P37/06 , A61P43/00
Abstract: "formas de administração farmacêutica mecanicamente estável para administração oral, e, processo para produzir formas de administração farmacêutica mecanicamente estável". a invenção diz respeito à formas de formas de administração farmacêutica mecanicamente estáveis para a administração peroral, que além de um ou mais ingredientes ativos e pelo menos um auxiliar formador de matriz termoplasticamente moldável, contêm mais do que 10 e até 40 % em peso de uma substância ativa de superfície que tenha um hlb entre 2 e 18 e seja líquida a 20 c ou tenha um ponto de gotejamento entre 20 e 50 c.
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公开(公告)号：BR0009299A
公开(公告)日：2001-12-18
申请号：BR0009299
申请日：2000-03-17
Applicant: BASF AG
Inventor： ROSENBERG JUERG , BERNDL GUNTHER , LIEPOLD BERND , BREITENBACH JUERG
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公开(公告)号：DE19842914A1
公开(公告)日：2000-03-23
申请号：DE19842914
申请日：1998-09-18
Applicant: BASF AG
Inventor： BREITENBACH JOERG , HEGER ROBERT , SIMON DIRK , LIEPOLD BERND
IPC: A61K9/14 , A61K47/22 , G01N33/48 , G01N33/483
Abstract: 1,3-Bis(pyrrolidon-1-yl) butane (I) is used as a dispersant or solvent in a test system for characterising the compatibiity of biologically active substances with polyvinylpyrrolidone (PVP) in a solid dispersion. Independent claims are also included for the following: (1) a test system for characterising the compatibility of biologically active substances with PVP in a solid dispersion, consisting of one or more biologically active substances and (I); (2) a method for characterising the compatibility of biologically active substances with PVP in a solid dispersion, comprising dissolving or dispersing one or more biologically active substances in (I) and spectroscopically evaluating the solution or dispersion.
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公开(公告)号：BRPI0009299B1
公开(公告)日：2011-05-17
申请号：BRPI0009299
申请日：2000-03-17
Applicant: BASF AG
Inventor： LIEPOLD BERND , ROSENBERG JOERG , BERNDL GUNTHER , BREITENBACH JOERG
IPC: A61K47/10 , A61K9/16 , A61K9/20 , A61K47/14 , A61K47/34 , A61P31/10 , A61P35/00 , A61P37/06 , A61P43/00
Abstract: The present invention relates to mechanically stable pharmaceutical presentations for oral administration, comprising in addition to one or more active ingredients and at least one melt-processable matrix-forming excipient more than 10 and up to 40% by weight of a surface-active substance with an HLB of from 2 to 18, which is liquid at 20° C. or has a drop point in the range from 20 to 50° C.
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公开(公告)号：DE50005515D1
公开(公告)日：2004-04-08
申请号：DE50005515
申请日：2000-03-17
Applicant: BASF AG
Inventor： ROSENBERG JOERG , BERNDL GUNTHER , LIEPOLD BERND , BREITENBACH JOERG
IPC: A61K47/10 , A61K9/16 , A61K9/20 , A61K47/14 , A61K47/34 , A61P31/10 , A61P35/00 , A61P37/06 , A61P43/00
Abstract: The present invention relates to mechanically stable pharmaceutical presentations for oral administration, comprising in addition to one or more active ingredients and at least one melt-processable matrix-forming excipient more than 10 and up to 40% by weight of a surface-active substance with an HLB of from 2 to 18, which is liquid at 20° C. or has a drop point in the range from 20 to 50° C.
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