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公开(公告)号:CA1270467A
公开(公告)日:1990-06-19
申请号:CA536719
申请日:1987-05-08
Applicant: BAXTER INT
Inventor: PATTILLO MARTHA C , BACEHOWSKI DAVID V , BILSTAD ARNOLD C , CULLIS HERBERT M , DENNEHEY T MICHAEL , YANG JAMES W , BROWN WILLIAM C
Abstract: SYSTEM FOR METERING NUTRIENT MEDIA TO CELL CULTURE CONTAINERS AND METHOD A system for metering nutrient media to cell culture containers includes a media flow conduit which defines at one end means for substantially aseptic communication with the source of the media. In a preferred embodiment, sterile connectors may be used from essentially sterile conditions. A branch conduit extends from the flow conduit at a location spaced from the ends. The branch conduit communicates with means for receiving a predetermined-volume aliquot of media through the media flow conduit from said one end. The flow conduit also defines a portion downstream from the branch conduit, which communicates with at least one cell culture container, each container being a flexible bag. At least part of the flexible bag is made of a material capable of providing at least 2 times the oxygen diffusion and at least 2 times the carbon dioxide diffusion between the bag interior and exterior, compared with an identically-sized, scaled bag having polyethylene walls 0.013 inch thick.
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公开(公告)号:DE602004007004T2
公开(公告)日:2008-02-07
申请号:DE602004007004
申请日:2004-07-21
Applicant: BAXTER INT
Inventor: DANBY HAL C , SCHARF MICHAEL W , SWAN JULIAN FRANCIS , BACEHOWSKI DAVID V
Abstract: A flexible bag having expansible and collapsible cells can be used in a liquid dispenser. A rigid manifold, and in one instance a rigid frame is provided in the bag to keep passages open in use and to isolate one of the cells from the remaining cells. The manifold is capable of altering the volume of one of the cells so that the same bag can be used in different applications.
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公开(公告)号:AT211759T
公开(公告)日:2002-01-15
申请号:AT95937666
申请日:1995-10-27
Applicant: BAXTER INT
Inventor: SMITH SIDNEY T , BACEHOWSKI DAVID V , KOLANKO WILLIAM , ROSENBAUM LARRY , SMITH STEPHEN L , LING MICHAEL T K , WOO LECON , BENDER JAMES G
Abstract: A multi-layer, flexible, gas-permeable film (10) suitable for forming a cell culture container (20), the film (10) comprising a first layer (12) composed of a polystyrene having a thickness within the range of 0.0001 inches to about 0.0010 inches and, a second layer (14) adhered to the first layer (12) composed of a polyolefin having a thickness within the range of 0.004 inches to about 0.015 inches.
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公开(公告)号:AU5544080A
公开(公告)日:1980-09-11
申请号:AU5544080
申请日:1980-02-12
Applicant: BAXTER INT
Inventor: BACEHOWSKI DAVID V , HEBRON TERRANCE J
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公开(公告)号:DE69815481T3
公开(公告)日:2008-03-06
申请号:DE69815481
申请日:1998-12-16
Applicant: BAXTER INT
Inventor: BINDOKAS ALGIRDAS J , LAL BIRENDRA K , BRAUSAM RAY , STONIS THOMAS A , JEPSON STEVEN C , SCHARF MICHAEL W , BACEHOWSKI DAVID V , LING MICHAEL T K , FORMAN HUGH M , RUDOLPH DANIEL J
Abstract: A resealable access site (10) is provided for allowing a cannula (18) multiple accesses to an internal cavity (35) defined by a container (12). The access site (10) includes a first conduit (28) defining a passageway (29) forming a fluid path to the cavity within the container. Sealingly attached to the conduit (28) is a housing (26) with a lower portion (26a) and a lower flange (68) attached to a lower end of the lower portion and extending radially inward from the lower portion. A septum (24) is disposed and compressed within the lower portion, with the septum defining an opening (46) extending upward through at least a portion of the septum. The opening (46) is sized for insertion of the cannula (18) through the septum (24) with the septum sealing about the exterior of the cannula. The septum (24) is maintained in the housing by the support provided by the opposing flange (68) and conduit (28).
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公开(公告)号:ES2289577T3
公开(公告)日:2008-02-01
申请号:ES04801900
申请日:2004-07-21
Applicant: BAXTER INT
Inventor: DANBY HAL C , SCHARF MICHAEL W , SWAN JULIAN FRANCIS RALPH , BACEHOWSKI DAVID V
Abstract: Recipiente flexible (9) para distribuir cantidades dosificadas de material fluido, comprendiendo el recipiente: una primera hoja flexible (55, 655); una segunda hoja flexible (57, 657) al menos parcialmente opuesta a la primera hoja de manera que las hojas primera y segunda definen como mínimo una célula (69) que puede contener el material fluido, pudiendo las hojas primera y segunda acercarse y alejarse entre sí a fin de poder utilizarlas para aspirar material fluido en la célula y descargar material fluido de la célula; un colector (95, 495, 695) situado entre las hojas primera y segunda para hacer pasar el material fluido al interior del recipiente, incluyendo el colector una estructura de orificio que se extiende hasta el interior de dicha célula y definiendo un orificio (101) que proporciona comunicación fluida entre la célula y el colector, caracterizado porque la estructura de orificio es sustancialmente rígida para separar las hojas primera y segunda y mantener el orificio abierto.
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公开(公告)号:DE602004007004D1
公开(公告)日:2007-07-26
申请号:DE602004007004
申请日:2004-07-21
Applicant: BAXTER INT
Inventor: DANBY HAL C , SCHARF MICHAEL W , SWAN JULIAN FRANCIS , BACEHOWSKI DAVID V
Abstract: A flexible bag having expansible and collapsible cells can be used in a liquid dispenser. A rigid manifold, and in one instance a rigid frame is provided in the bag to keep passages open in use and to isolate one of the cells from the remaining cells. The manifold is capable of altering the volume of one of the cells so that the same bag can be used in different applications.
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公开(公告)号:CA2195628C
公开(公告)日:2005-04-19
申请号:CA2195628
申请日:1996-04-30
Applicant: BAXTER INT
Inventor: ROSENBAUM LARRY A , GIOVANETTO STEVEN , SMITH SIDNEY T , BACEHOWSKI DAVID V , NEBGEN GREGG , KALYANKAR VARSHA
IPC: B32B27/28 , B32B27/08 , B32B27/30 , B32B27/32 , C08L23/08 , C08L23/10 , C08L25/04 , C08L53/00 , C08L53/02 , C08L77/00
Abstract: A multiple layer structure comprising a skin layer, a barrier layer, a radio frequency susceptible layer having a first polyolefin in an amount within a range of 30-60 % by weight, a second polyolefin in an amount within the range of 25-50 % by weight, a radio frequency susceptible polymer in an amount within the range of 3-40 % by weight, a styrene and hydrocarbon block copolymer in an amount within the range of 5-40 % by weight of the sealant layer.
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公开(公告)号:AU2003293486A8
公开(公告)日:2004-08-23
申请号:AU2003293486
申请日:2003-12-10
Applicant: BAXTER INT
Inventor: ZAHEDI MIR S , SWAN JULIAN FRANCIS RALPH , BACEHOWSKI DAVID V , HONE TIMOTHY , DANBY HAL C , HAYES-PANKHURST RICHARD P , SCHARF MICHAEL W
Abstract: A liquid dispenser uses a flexible bag having expansible and collapsible cells. A rigid manifold is provided in the bag to keep passages open in use and to isolate one of the cells from the remaining cells. In one application, a concentrated drink mix may be held in a reservoir and diluted within other cells in the bag for dispensing to a cup or the like. A valve system allows for the particulates in the liquid without compromising the function of the valve.
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公开(公告)号:CA2195628A1
公开(公告)日:1996-12-19
申请号:CA2195628
申请日:1996-04-30
Applicant: BAXTER INT
Inventor: ROSENBAUM LARRY A , GIOVANETTO STEVEN , SMITH SIDNEY T , BACEHOWSKI DAVID V , NEBGEN GREGG , KALYANKAR VARSHA
IPC: B32B27/28 , B32B27/08 , B32B27/30 , B32B27/32 , C08L23/08 , C08L23/10 , C08L25/04 , C08L53/00 , C08L53/02 , C08L77/00
Abstract: A multiple layer structure comprising a skin layer, a barrier layer, a radio frequency susceptible layer having a first polyolefin in an amount within a range of 30-60% by weight, a second polyolefin in an amount within the range of 25-50% by weight, a radio frequency susceptible polymer in an amount within the range of 3-40% by weight, a styrene and hydrocarbon block copolymer in an amount within the range of 5-40% by weight of the sealant layer.
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