SYSTEM FOR METERING NUTRIENT MEDIA TO CELL CULTURE CONTAINERS AND METHOD

    公开(公告)号:CA1270467A

    公开(公告)日:1990-06-19

    申请号:CA536719

    申请日:1987-05-08

    Applicant: BAXTER INT

    Abstract: SYSTEM FOR METERING NUTRIENT MEDIA TO CELL CULTURE CONTAINERS AND METHOD A system for metering nutrient media to cell culture containers includes a media flow conduit which defines at one end means for substantially aseptic communication with the source of the media. In a preferred embodiment, sterile connectors may be used from essentially sterile conditions. A branch conduit extends from the flow conduit at a location spaced from the ends. The branch conduit communicates with means for receiving a predetermined-volume aliquot of media through the media flow conduit from said one end. The flow conduit also defines a portion downstream from the branch conduit, which communicates with at least one cell culture container, each container being a flexible bag. At least part of the flexible bag is made of a material capable of providing at least 2 times the oxygen diffusion and at least 2 times the carbon dioxide diffusion between the bag interior and exterior, compared with an identically-sized, scaled bag having polyethylene walls 0.013 inch thick.

    15.
    发明专利
    未知

    公开(公告)号:DE69815481T3

    公开(公告)日:2008-03-06

    申请号:DE69815481

    申请日:1998-12-16

    Applicant: BAXTER INT

    Abstract: A resealable access site (10) is provided for allowing a cannula (18) multiple accesses to an internal cavity (35) defined by a container (12). The access site (10) includes a first conduit (28) defining a passageway (29) forming a fluid path to the cavity within the container. Sealingly attached to the conduit (28) is a housing (26) with a lower portion (26a) and a lower flange (68) attached to a lower end of the lower portion and extending radially inward from the lower portion. A septum (24) is disposed and compressed within the lower portion, with the septum defining an opening (46) extending upward through at least a portion of the septum. The opening (46) is sized for insertion of the cannula (18) through the septum (24) with the septum sealing about the exterior of the cannula. The septum (24) is maintained in the housing by the support provided by the opposing flange (68) and conduit (28).

    DISTRIBUIDOR DE LIQUIDO Y BOLSA FLEXIBLE ASOCIADA.

    公开(公告)号:ES2289577T3

    公开(公告)日:2008-02-01

    申请号:ES04801900

    申请日:2004-07-21

    Applicant: BAXTER INT

    Abstract: Recipiente flexible (9) para distribuir cantidades dosificadas de material fluido, comprendiendo el recipiente: una primera hoja flexible (55, 655); una segunda hoja flexible (57, 657) al menos parcialmente opuesta a la primera hoja de manera que las hojas primera y segunda definen como mínimo una célula (69) que puede contener el material fluido, pudiendo las hojas primera y segunda acercarse y alejarse entre sí a fin de poder utilizarlas para aspirar material fluido en la célula y descargar material fluido de la célula; un colector (95, 495, 695) situado entre las hojas primera y segunda para hacer pasar el material fluido al interior del recipiente, incluyendo el colector una estructura de orificio que se extiende hasta el interior de dicha célula y definiendo un orificio (101) que proporciona comunicación fluida entre la célula y el colector, caracterizado porque la estructura de orificio es sustancialmente rígida para separar las hojas primera y segunda y mantener el orificio abierto.

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