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    BIOSENSOR CHIP
    11.
    发明申请
    BIOSENSOR CHIP 审中-公开
    生物传感器芯片

    公开(公告)号：WO0175141A3

    公开(公告)日：2002-05-10

    申请号：PCT/DE0101241

    申请日：2001-03-29

    Applicant: INFINEON TECHNOLOGIES AG ,  FREY ALEXANDER ,  THEWES ROLAND

    Inventor： FREY ALEXANDER ,  THEWES ROLAND

    IPC: G01N33/53 ,  C12M1/00 ,  C12N15/09 ,  G01N27/327 ,  G01N27/416 ,  G01N33/543 ,  C12Q1/68 ,  G01N27/403

    CPC classification number: G01N33/5438 ,  G01N27/3277

    Abstract: The invention relates to a biosensor chip that is provided with a first electrode and a second electrode. The first electrode is provided with a holding area for holding probe molecules which can bind macromolecular biopolymers. The invention also relates to an integrated electric differentiating circuit by means of which an electric current can be detected and can be differentiated according to time, whereby said current is generated during a reduction/oxidation recycling procedure.

    Abstract translation: 该生物传感器包括第一电极和第二电极。 所述第一电极具有用于保持可结合大分子生物聚合物的探针分子的保持区域。 此外，提供了一种集成电微分电路，其检测一个还原/氧化循环操作期间产生的，并且电流可以根据时间来区分。

    15.
    发明专利
    未知

    公开(公告)号：DE50212968D1

    公开(公告)日：2008-12-11

    申请号：DE50212968

    申请日：2002-07-10

    Applicant: INFINEON TECHNOLOGIES AG

    Inventor： BREDERLOW RALF ,  EVERSMANN BJOERN-OLIVER ,  KOREN IVO ,  PAULUS CHRISTIAN ,  THEWES ROLAND

    IPC: G01N33/487 ,  G01N27/414 ,  G01N27/416 ,  G01N33/483 ,  G01N37/00 ,  G11C27/02 ,  H03F3/45

    Abstract: A measuring cell for recording an electrical potential of an analyte situated on the measuring cell. The measuring cell has a sensor, a layer arranged above the sensor and electrically insulating the analyte from the sensor, and an amplifier circuit connected to the sensor on a substrate and having an input stage containing a field-effect transistor or a bipolar transistor, the sensor being at least indirectly connected to a control terminal of the field-effect transistor or of the bipolar transistor. An operating point of the amplifier circuit is set by means of a voltage or a current applied at the control terminal of the field-effect transistor or of the bipolar transistor of the input stage of the amplifier circuit.

    17.
    发明专利
    未知

    公开(公告)号：DE10259820B4

    公开(公告)日：2006-05-24

    申请号：DE10259820

    申请日：2002-12-19

    Applicant: SIEMENS AG ,  INFINEON TECHNOLOGIES AG

    Inventor： GUMBRECHT WALTER ,  MUND KONRAD ,  SCHIENLE MEINRAD ,  THEWES ROLAND

    IPC: G01N33/50 ,  C12M1/00 ,  C12Q1/68 ,  G01N33/543

    Abstract: A DNA chip includes a carrier and a microarray of spots containing immobilised catcher molecules which are arranged on the carrier. Each spot contains a microelectrode system for the impedance spectroscopic detection of binding events occurring between the catcher molecules and target molecules of an analyte solution applied to the spots. The microelectrode system has a pair of polarisation electrodes in order to produce an alternating electromagnetic field and a pair of sensor electrodes for measuring a voltage drop in the analyte.

    18.
    发明专利
    未知

    公开(公告)号：AT303594T

    公开(公告)日：2005-09-15

    申请号：AT01987879

    申请日：2001-10-16

    Applicant: INFINEON TECHNOLOGIES AG

    Inventor： FREY ALEXANDER ,  PAULUS CHRISTIAN ,  THEWES ROLAND

    IPC: G01N33/53 ,  G01D3/02 ,  G01N27/02 ,  G01N27/22 ,  G01N27/327 ,  G01N27/333 ,  G01N27/414 ,  G01N27/416 ,  G01N27/49 ,  G01N37/00

    Abstract: In a first phase a first sensor signal, essentially comprising the current offset signal of the sensor, is applied to the input of an electronic circuit. The first sensor signal is fed to a first signal path and stored therein. In a second phase a second sensor signal, comprising the current offset signal and a time-dependent measured signal, is applied to the input and the stored first sensor signal is fed to the input by means of the first signal path, such that essentially the time dependent measured signal is fed by means of a second signal path coupled to the input.

    19.
    发明专利
    未知

    公开(公告)号：DE10204652B4

    公开(公告)日：2004-07-22

    申请号：DE10204652

    申请日：2002-02-05

    Applicant: INFINEON TECHNOLOGIES AG

    Inventor： PAULUS CHRISTIAN ,  SCHIENLE MEINRAD ,  THEWES ROLAND ,  FREY ALEXANDER

    IPC: G01N27/416 ,  G01N27/02 ,  G01N27/327 ,  G01N27/403 ,  G01N37/00 ,  G01N33/50 ,  C12Q1/68

    Abstract: Circuit arrangement having a sensor electrode, a first circuit unit, which is electrically coupled to the sensor electrode, and a second circuit unit, which has a first capacitor. The first circuit unit holds an electrical potential of the sensor electrode in a predetermined first reference range around a predetermined electrical desired potential by coupling the first capacitor and the sensor electrode such that there is a matching of their electrical potentials. If the second circuit unit detects the electrical potential of the first capacitor being outside a second reference range, the second circuit unit brings the first capacitor to a first electrical reference potential.

    20.
    发明专利
    未知

    公开(公告)号：DE10259820A1

    公开(公告)日：2004-07-01

    申请号：DE10259820

    申请日：2002-12-19

    Applicant: SIEMENS AG ,  INFINEON TECHNOLOGIES AG

    Inventor： GUMBRECHT WALTER ,  MUND KONRAD ,  SCHIENLE MEINRAD ,  THEWES ROLAND

    IPC: C12Q1/68 ,  G01N33/543 ,  G01N33/50 ,  C12M1/00

    Abstract: A DNA chip includes a carrier and a microarray of spots containing immobilised catcher molecules which are arranged on the carrier. Each spot contains a microelectrode system for the impedance spectroscopic detection of binding events occurring between the catcher molecules and target molecules of an analyte solution applied to the spots. The microelectrode system has a pair of polarisation electrodes in order to produce an alternating electromagnetic field and a pair of sensor electrodes for measuring a voltage drop in the analyte.

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