公开(公告)号：DE3543496A1

公开(公告)日：1986-06-19

申请号：DE3543496

申请日：1985-12-09

Applicant: KAO CORP

Inventor： NAKAMURA KOICHI ,  HORI KIMIHIKO ,  HATTORI MICHIHIRO ,  TEJIMA TORU ,  IMOKAWA GENJI ,  TAKAISHI NAOTAKE

IPC: C07C65/32 ,  A61K8/368 ,  A61Q17/04 ,  C07C51/00 ,  C07C51/373 ,  C07C65/40 ,  C07C67/00 ,  A61K7/42

Abstract: 4-methoxy-2'-carboxydibenzoylmethane of the following general formula (I) (I) is prepared by reacting p-methoxyacetophenone (III) with phthalic anhydride (II) in accordance with the following reaction equation. +TR The compound (I) and its salts absorb both UV-A and UV-B, and exhibit prominent effects as a ultraviolet absorber for cosmetic formulations such as skin cosmetic formulations and hair cosmetic formulations.

公开(公告)号：DE69906856D1

公开(公告)日：2003-05-22

申请号：DE69906856

申请日：1999-01-14

Applicant: KAO CORP

Inventor： TSUJI NAOKO ,  MORIWAKI SHIGERU ,  OHUCHI ATSUSHI ,  TAKEMA YOSHINORI ,  SUZUKI YASUTO ,  IMOKAWA GENJI

IPC: A61K8/00 ,  A61K8/44 ,  A61K8/55 ,  A61K31/195 ,  A61K31/66 ,  A61K31/675 ,  A61K31/70 ,  A61K45/00 ,  A61P17/00 ,  A61Q5/00 ,  A61Q7/02 ,  A61Q9/04 ,  A61K7/06 ,  A61K7/155

Abstract: Disclosed herein are a method of inhibiting hair growth, which comprises administering an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor, and use of an inhibitor of elastase-like enzymes or a neutral endopeptidase inhibitor for the preparation of a hair-growth inhibitor.

公开(公告)号：DE69209513D1

公开(公告)日：1996-05-02

申请号：DE69209513

申请日：1992-09-22

Applicant: KAO CORP

Inventor： OHASHI YUKIHIRO ,  FUJIMORI TAKETOSHI ,  NAGAI MINORU ,  KAWAMATA AKIRA ,  YADA YUKIHIRO ,  HIGUCHI KAZUHIKO ,  IMOKAWA GENJI ,  TAKEMA YOSHINORI ,  SAKAINO YUKIKO ,  OGAWA AYUMI ,  FUJIMURA TSUTOMU

IPC: A61K8/41 ,  A61K31/13 ,  A61Q19/00 ,  A61Q19/08 ,  A61K7/48

Abstract: PCT No. PCT/JP92/01210 Sec. 371 Date Mar. 23, 1994 Sec. 102(e) Date Mar. 23, 1994 PCT Filed Sep. 22, 1992 PCT Pub. No. WO93/05763 PCT Pub. Date Apr. 1, 1993A composition for external skin care comprising an amine derivative represented by the following formula (1), (1) wherein R1 is a linear, branched, or cyclic saturated or unsaturated hydrocarbon group having 4-40 carbon atoms, and R2, R3, R4, R5 and R6 are individually a hydrogen atom or a hydrocarbon group having 1-10 carbon atoms, which may be substituted or unsubstituted by 1 or more hydroxy groups; or an acid addition salt thereof, in an amount from 0.0001 to less than 0.1% by weight; and a method of curing wrinkles and keratinization of the skin characterized by applying said amine derivative or its salt to the skin.

公开(公告)号：ES2012045B3

公开(公告)日：1990-03-01

申请号：ES86117200

申请日：1986-12-10

Applicant: KAO CORP

Inventor： KAWAMATA AKIRA ,  YANO SHINJI ,  HATTORI MICHIHIRO ,  AKAZAKI SHUICHI ,  IMOKAWA GENJI ,  TAKAISHI NAOTAKE

IPC: A61K8/30 ,  A61K8/00 ,  A61K8/42 ,  A61K8/68 ,  A61K31/16 ,  A61P17/00 ,  A61Q19/00 ,  C07C67/00 ,  C07C231/00 ,  C07C233/18 ,  C07C233/20 ,  C09K23/22 ,  F16K31/18

公开(公告)号：GB2213723A

公开(公告)日：1989-08-23

申请号：GB8905357

申请日：1989-03-09

Applicant: KAO CORP

Inventor： HATTORI MICHIHIRO ,  AKAZAKI SHUICHI ,  YOSHIZUKA NAONOBU ,  IMOKAWA GENJI

IPC: A61K8/96 ,  A61K8/00 ,  A61K8/06 ,  A61K8/34 ,  A61K8/92 ,  A61K8/98 ,  A61K31/00 ,  A61K35/36 ,  A61Q19/00

公开(公告)号：FR2574399B1

公开(公告)日：1989-05-05

申请号：FR8518341

申请日：1985-12-11

Applicant: KAO CORP

Inventor： NAKAMURA KOICHI ,  HORI KIMIHIKO ,  HATTORI MICHIHIRO ,  TEJIMA TORU ,  IMOKAWA GENJI ,  TAKAISHI NAOTAKE

IPC: C07C65/32 ,  A61K8/368 ,  A61Q17/04 ,  C07C51/00 ,  C07C51/373 ,  C07C65/40 ,  C07C67/00 ,  C07C51/083 ,  A61K7/44

Abstract: 4-methoxy-2'-carboxydibenzoylmethane of the following general formula (I) (I) is prepared by reacting p-methoxyacetophenone (III) with phthalic anhydride (II) in accordance with the following reaction equation. +TR The compound (I) and its salts absorb both UV-A and UV-B, and exhibit prominent effects as a ultraviolet absorber for cosmetic formulations such as skin cosmetic formulations and hair cosmetic formulations.

公开(公告)号：CH665205A5

公开(公告)日：1988-04-29

申请号：CH526985

申请日：1985-12-10

Applicant: KAO CORP

Inventor： NAKAMURA KOICHI ,  HORI KIMIHIKO ,  HATTORI MICHIHIRO ,  TEJIMA TORU ,  IMOKAWA GENJI ,  TAKAISHI NAOTAKE

IPC: C07C65/32 ,  A61K8/368 ,  A61Q17/04 ,  C07C51/00 ,  C07C51/373 ,  C07C65/40 ,  C07C67/00 ,  A61K7/44

公开(公告)号：FR2555167B1

公开(公告)日：1987-07-24

申请号：FR8417487

申请日：1984-11-16

Applicant: KAO CORP

Inventor： TEJIMA TOHRU ,  NAKAMURA KOICHI ,  HATTORI MICHIHIRO ,  MASUDA SHINICHI ,  IMOKAWA GENJI ,  TAKAISHI NAOTAKE

IPC: C07C69/28 ,  A61K8/00 ,  A61K8/33 ,  A61K8/37 ,  A61K31/235 ,  A61Q17/04 ,  C07C69/017 ,  C07C69/035 ,  C07C69/24 ,  C07C69/527 ,  C07C69/533 ,  C09K3/00 ,  A61K7/42

公开(公告)号：AT27230T

公开(公告)日：1987-06-15

申请号：AT84107662

申请日：1984-07-02

Applicant: KAO CORP

Inventor： YOSHIZUKA NAONOBU ,  TAKEUCHI EIJIRO ,  IMOKAWA GENJI

IPC: A61K31/575 ,  A61K8/63 ,  A61P3/00 ,  A61P3/06 ,  A61P17/00 ,  A61Q19/00 ,  C07J9/00 ,  A61K7/48

Abstract: Sebum secretion accelerator composition comprising a cholesteryl ester of a branched fatty acid represented by the formula (I): (I) in which R represents a saturated aliphatic hydrocarbon group having from 11 to 23 carbon atoms and at least one alkyl substituent at a position between the carboxyl bond and the center of the main chain. The cholesteryl ester should be contained not smaller than 25 wt % of the total composition. The composition according to the invention promotes sebum secretion, and is effective in keeping healthy and beautiful skin. The composition is further advantageous in that it can be readily formed into various types of cosmetics such as lotions, creams and ointments.

公开(公告)号：GB2149789B

公开(公告)日：1987-05-07

申请号：GB8427998

申请日：1984-11-06

Applicant: KAO CORP

Inventor： TEJIMA TOHRU ,  NAKAMURA KOICHI ,  HATTORI MICHIHIRO ,  MASUDA SHINICHI ,  IMOKAWA GENJI ,  TAKAISHA NAOTAKE

IPC: C07C69/28 ,  A61K8/00 ,  A61K8/33 ,  A61K8/37 ,  A61K31/235 ,  A61Q17/04 ,  C07C69/017 ,  C07C69/035 ,  C07C69/24 ,  C07C69/527 ,  C07C69/533 ,  C09K3/00 ,  A61K7/42