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公开(公告)号：AU2014348203A1
公开(公告)日：2016-07-07
申请号：AU2014348203
申请日：2014-11-18
Applicant: LIFE TECHNOLOGIES CORP
Inventor： LIM GARY , STRAUB THEODORE
IPC: B01L3/02
Abstract: A sample loader for loading a liquid sample into a plurality of reaction sites within a substrate is provided. The sample loader includes a first blade, and a second blade coupled to the first blade. The sample loader further comprises a flow path between the first blade and second blade configured to dispense a liquid sample to a substrate including a plurality of reaction sites. Further, in various embodiments the liquid sample has an advancing contact angle of 85 +/- 15 degrees with the first and second blade. Furthermore, loading of the liquid sample dispensed from the flow path to the plurality of reaction sites may be based on capillary action. The first and second blade may dispense the liquid by laterally moving over the plurality of reaction sites, where a motor laterally moves the first and second blade.
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公开(公告)号：CA2934187A1
公开(公告)日：2015-05-21
申请号：CA2934187
申请日：2014-11-18
Applicant: LIFE TECHNOLOGIES CORP
Inventor： LIM GARY , STRAUB THEODORE
IPC: B01L3/02
Abstract: A sample loader for loading a liquid sample into a plurality of reaction sites within a substrate is provided. The sample loader includes a first blade, and a second blade coupled to the first blade. The sample loader further comprises a flow path between the first blade and second blade configured to dispense a liquid sample to a substrate including a plurality of reaction sites. Further, in various embodiments the liquid sample has an advancing contact angle of 85 +/- 15 degrees with the first and second blade. Furthermore, loading of the liquid sample dispensed from the flow path to the plurality of reaction sites may be based on capillary action. The first and second blade may dispense the liquid by laterally moving over the plurality of reaction sites, where a motor laterally moves the first and second blade.
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公开(公告)号：AU2013231910A1
公开(公告)日：2014-10-30
申请号：AU2013231910
申请日：2013-03-15
Applicant: LIFE TECHNOLOGIES CORP
Inventor： PALLAS MICHAEL C , NURSE JAMES , LIM GARY , STRAUB THEODORE , GHENCIU ELIODOR , FOSTER EVAN , FONSECA JORGE , MAHER KEVIN
Abstract: A system for performing biological reactions is provided. The system includes a chip including a substrate and a plurality of reaction sites. The plurality of reaction sites are each configured to include a liquid sample of at most one nanoliter. Further, the system includes a control system configured to initiate biological reactions within the liquid samples. The system further includes a detection system configured to detect biological reactions on the chip. According to various embodiments, the chip includes at least 20000 reaction sites. In other embodiments, the chip includes at least 30000 reaction sites.
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Patent Agency Ranking
公开(公告)号：SG11201405787SA
公开(公告)日：2014-11-27
申请号：SG11201405787S
申请日：2013-03-15
Applicant: LIFE TECHNOLOGIES CORP
Inventor： PALLAS MICHAEL C , NURSE JAMES , LIM GARY , STRAUB THEODORE , FOSTER EVAN
Abstract: An apparatus for biological reactions is provided. The apparatus includes a substrate and a plurality of reaction sites within the substrate. A surface of the substrate is configured to have a first hydrophilicity and each surface of the plurality of reaction sites is configured to have a second hydrophilicity to load a substantial number of reaction sites with a sample volume. The sample volume of each loaded reaction site is substantially confined to its respective reaction site. The sample volume is configured to undergo a biological reaction within the reaction site.
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公开(公告)号：SG11201405785WA
公开(公告)日：2014-11-27
申请号：SG11201405785W
申请日：2013-03-15
Applicant: LIFE TECHNOLOGIES CORP
Inventor： PALLAS MICHAEL C , NURSE JAMES , LIM GARY , STRAUB THEODORE , GHENCIU ELIODOR , FOSTER EVAN , FONSECA JORGE , MAHER KEVIN
Abstract: A system for performing biological reactions is provided. The system includes a chip including a substrate and a plurality of reaction sites. The plurality of reaction sites are each configured to include a liquid sample of at most one nanoliter. Further, the system includes a control system configured to initiate biological reactions within the liquid samples. The system further includes a detection system configured to detect biological reactions on the chip. According to various embodiments, the chip includes at least 20000 reaction sites. In other embodiments, the chip includes at least 30000 reaction sites.
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公开(公告)号：AU2013231955A1
公开(公告)日：2014-10-30
申请号：AU2013231955
申请日：2013-03-15
Applicant: LIFE TECHNOLOGIES CORP
Inventor： PALLAS MICHAEL C , NURSE JAMES , LIM GARY , STRAUB THEODORE , FOSTER EVAN
IPC: B01L3/02
Abstract: A sample loader for loading a liquid sample into a plurality of reaction sites within a substrate is provided. The sample loader includes a first blade, and a second blade coupled to the first blade. The sample loader further comprises a flow path between the first blade and second blade configured to dispense a liquid sample to a substrate including a plurality of reaction sites. Further, in various embodiments the liquid sample has an advancing contact angle of 85 +/- 15 degrees with the first and second blade. Furthermore, loading of the liquid sample dispensed from the flow path to the plurality of reaction sites may be based on capillary action.
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公开(公告)号：SG11201401913YA
公开(公告)日：2014-09-26
申请号：SG11201401913Y
申请日：2012-09-28
Applicant: LIFE TECHNOLOGIES CORP
Inventor： FREUDENTHAL JACOB K , DAHLHOFF GEOFFREY , MAHER KEVIN , CHEN MINGSONG , LIM GARY , DANEHY RONALD , FORTESCUE DAVID , SHEN MING , SOH WOON LIANG TERENCE , CHENG FRANCIS , WU RUOYUN , LEE THIAM CHYE , CHAPPELL GARY , LIM CHEE KIONG , DERE JEFF , STRAUB TED , FONSECA JORGE , BOO KUAN MOON , LAU SOO YONG
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公开(公告)号：EP2170514A4
公开(公告)日：2011-08-03
申请号：EP08768740
申请日：2008-06-25
Applicant: LIFE TECHNOLOGIES CORP
Inventor： LIU DAVID M , LIM GARY , YEE VICTOR H
IPC: B01L3/00
CPC classification number: B01L3/5085 , B01L3/50851 , B01L2200/12 , B01L2300/0829 , B01L2300/0851 , B01L2300/12 , B29C45/16 , B29C2045/002 , B29L2031/756
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