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    OPTICAL SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS
    3.
    发明专利
    OPTICAL SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS 未知

    公开(公告)号：IN3441DEN2014A

    公开(公告)日：2015-06-05

    申请号：IN3441DEN2014

    申请日：2014-04-29

    Applicant: LIFE TECHNOLOGIES CORP

    Inventor： MAHER KEVIN ,  CHEN MINGSONG ,  FREUDENTHAL JACOB ,  BOO KUAN MOON ,  LAU SOO YONG ,  FORTESCUE DAVID ,  SHEN MING ,  SOH WOON LIANG TERENCE

    IPC: G01N21/64

    Abstract: An instrument (1000) for processing and/or measuring a biological process contains an excitation source (110) a sample holder (204) an optical sensor (118) an excitation optical system (120) and an emission optical system (125). The sample holder (204) is configured to receive a plurality of biological samples. The optical sensor (118) is configured to receive an emission from the biological samples. The excitation optical system (120) is disposed along an excitation optical path (126) and is configured to direct the electromagnetic radiation from the excitation source (110) to the biological samples. The emission optical system (125) is disposed along an emission optical path (128) and is configured to direct electromagnetic emissions from the biological samples to the optical sensor (118). The instrument further contains a plurality of filter assemblies (130 132) configured to be interchangeably located along at least one of the optical paths. The plurality of filter components (131) includes a first filter component (138) characterized by a first optical power and a first filter (140) having a first filter function the first filter function characterized by at least one of a first low pass wavelength or a first high pass wavelength. The second filter assembly (142) is characterized by a second optical power and a second filter (145) having a second filter function the second filter function comprising at least one of a second low pass wavelength that is different than the first low pass wavelength or a second high pass wavelength that is different than the first high pass wavelength. The second optical power differs from the first optical power by an amount sufficient to at least partially compensate for an aberration introduced by the second filter (145) relative to the first filter (140).

    METHODS AND SYSTEMS FOR VISUALIZING AND EVALUATING DATA
    4.
    发明专利
    METHODS AND SYSTEMS FOR VISUALIZING AND EVALUATING DATA 未知

    公开(公告)号：SG10201604446PA

    公开(公告)日：2016-07-28

    申请号：SG10201604446P

    申请日：2012-09-28

    Applicant: LIFE TECHNOLOGIES CORP

    Inventor： JANAWAY GORDON ,  ALIMINATI MANJULA ,  WU RUOYUN ,  FORTESCUE DAVID ,  SHEN MING

    IPC: G16B45/00

    Abstract: A computer-implemented method of generating a digital polymerase chain reaction (dPCR) result is provided. The method includes detecting of emission data from a planiality of samples, each included in a sample region of a plurality of sample regions, at a first time amplification period. The method further includes determining a positive or negative amplification determination for each sample of the plurality of samples based in part on the first set of emission data, A dPCR result is generated based on the positive amplification determinations for the plurality of samples.

    METHODS AND SYSTEMS FOR VISUALIZING AND EVALUATING DATA
    6.
    发明专利
    METHODS AND SYSTEMS FOR VISUALIZING AND EVALUATING DATA 未知

    公开(公告)号：IN3407DEN2014A

    公开(公告)日：2015-06-05

    申请号：IN3407DEN2014

    申请日：2014-04-28

    Applicant: LIFE TECHNOLOGIES CORP

    Inventor： JANAWAY GORDON ,  ALIMINATI MANJULA ,  WU RUOYUN ,  FORTESCUE DAVID ,  SHEN MING

    IPC: C12Q1/68 ,  G16B45/00

    Abstract: A computer implemented method of generating a digital polymerase chain reaction (dPCR) result is provided. The method includes detecting a first set of emission data from a plurality of samples each included in a sample region of a plurality of sample regions at a first time during an amplification period. The method further includes determining a positive or negative amplification determination for each sample of the plurality of samples based in part on the first set of emission data. A dPCR result is generated based on the positive or negative amplification determinations for the plurality of samples.

    OPTICAL SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS
    8.
    发明专利
    OPTICAL SYSTEMS AND METHODS FOR BIOLOGICAL ANALYSIS 未知

    公开(公告)号：SG11201401919TA

    公开(公告)日：2014-10-30

    申请号：SG11201401919T

    申请日：2012-09-28

    Applicant: LIFE TECHNOLOGIES CORP

    Inventor： MAHER KEVIN ,  CHEN MINGSONG ,  FREUDENTHAL JACOB ,  BOO KUAN MOON ,  LAU SOO YONG ,  FORTESCUE DAVID ,  SHEN MING ,  SOH WOON LIANG TERENCE

    IPC: G01N21/64

    Abstract: An instrument for processing and/or measuring a biological process contains an excitation source, a sample holder, an optical sensor, an excitation optical system, and an emission optical system. The sample holder is configured to receive a plurality of biological samples. The optical sensor is configured to receive an emission from the biological samples. The excitation optical system is disposed along an excitation optical path and is configured to direct the electromagnetic radiation from the excitation source to the biological samples. The emission optical system is disposed along an emission optical path and is configured to direct electromagnetic emissions from the biological samples to the optical sensor. The instrument further contains a plurality of filter assemblies configured to be interchangeably located along at least one of the optical paths. The plurality of filter components includes a first filter assembly characterized by a first optical power and a first filter having a first filter function, the first filter function characterized by at least one of a first low-pass wavelength or a first high-pass wavelength. The second filter assembly is characterized by a second optical power and a second filter having a second filter function, the second filter function comprising at least one of a second low-pass wavelength that is different than the first low-pass wavelength or a second high-pass wavelength that is different than the first high-pass wavelength.

    METHODS AND SYSTEMS FOR VISUALIZING AND EVALUATING DATA
    9.
    发明专利
    METHODS AND SYSTEMS FOR VISUALIZING AND EVALUATING DATA 未知

    公开(公告)号：SG11201401917QA

    公开(公告)日：2014-09-26

    申请号：SG11201401917Q

    申请日：2012-09-28

    Applicant: LIFE TECHNOLOGIES CORP

    Inventor： JANAWAY GORDON ,  ALIMINATI MANJULA ,  WU RUOYUN ,  FORTESCUE DAVID ,  SHEN MING

    IPC: C12Q1/68 ,  G16B45/00

    Abstract: A computer-implemented method of generating a digital polymerase chain reaction (dPCR) result is provided. The method includes detecting of emission data from a planiality of samples, each included in a sample region of a plurality of sample regions, at a first time amplification period. The method further includes determining a positive or negative amplification determination for each sample of the plurality of samples based in part on the first set of emission data, A dPCR result is generated based on the positive amplification determinations for the plurality of samples.

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