-
公开(公告)号：WO2013049702A3
公开(公告)日：2013-10-10
申请号：PCT/US2012058096
申请日：2012-09-28
Applicant: LIFE TECHNOLOGIES CORP
Inventor： FREUDENTHAL JACOB K , DAHLHOFF GEOFFREY , MAHER KEVIN , CHEN MINGSONG , LIM GARY , DANEHY RONALD , FORTESCUE DAVID , SHEN MING , SOH WOON LIANG TERENCE , CHENG FRANCIS , WU RUOYUN , LEE THIAM CHYE , CHAPPELL GARY , LIM CHEE KIONG , DERE JEFF , STRAUB TED , FONSECA JORGE , BOO KUAN MOON , LAU SOO YONG
CPC classification number: C12Q1/686 , B01L3/50855 , B01L3/50857 , B01L7/52 , B01L2200/023 , B01L2200/025 , B01L2200/028 , B01L2200/143 , B01L2300/021 , B01L2300/046 , B01L2300/0654 , B01L2300/0829 , B01L2300/1827 , B01L2300/1844
Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lens can be a bi-convex lens.
Abstract translation: 提供生物分析系统。 该系统包括被配置为容纳多个样本保持器中的任何一个的可互换组件，每个相应样本保持器被配置为接收多个样本。 该系统还包括配置成循环多个样品通过一系列温度的控制系统。 该系统还包括配置成检测从多个样品发射的荧光信号的光学系统。 该光学系统尤其可以包括单个场透镜，激励源，光学传感器和多个滤波器组件。 激发源可以是一个或多个发光二极管。 场镜可以是双凸透镜。
-
公开(公告)号：WO2013049702A2
公开(公告)日：2013-04-04
申请号：PCT/US2012058096
申请日：2012-09-28
Applicant: LIFE TECHNOLOGIES CORP
Inventor： FREUDENTHAL JACOB K , DAHLHOFF GEOFFREY , MAHER KEVIN , CHEN MINGSONG , LIM GARY , DANEHY RONALD , FORTESCUE DAVID , SHEN MING , SOH WOON LIANG TERENCE , CHENG FRANCIS , WU RUOYUN , LEE THIAM CHYE , CHAPPELL GARY , LIM CHEE KIONG , DERE JEFF , STRAUB TED , FONSECA JORGE , BOO KUAN MOON , LAU SOO YONG
CPC classification number: C12Q1/686 , B01L3/50855 , B01L3/50857 , B01L7/52 , B01L2200/023 , B01L2200/025 , B01L2200/028 , B01L2200/143 , B01L2300/021 , B01L2300/046 , B01L2300/0654 , B01L2300/0829 , B01L2300/1827 , B01L2300/1844
Abstract: A biological analysis system is provided. The system comprises an interchangeable assembly configured to accommodate any one of a plurality of sample holders, each respective sample holder configured to receive a plurality of samples. The system also includes a control system configured to cycle the plurality of samples through a series of temperatures. The system further includes an optical system configured to detect fluorescent signals emitted from the plurality of samples. The optical system, in particular, can comprise a single field lens, an excitation source, an optical sensor, and a plurality of filter components. The excitation source can be one or more light emitting diodes. The field lens can be a bi-convex lens.
Abstract translation: 提供生物分析系统。 该系统包括被配置为容纳多个样品保持器中的任何一个的可互换组件，每个样品保持器被配置为接收多个样品。 该系统还包括被配置为使多个样品循环通过一系列温度的控制系统。 该系统还包括被配置为检测从多个样本发射的荧光信号的光学系统。 特别地，光学系统可以包括单个场透镜，激发源，光学传感器和多个滤光器组件。 激发源可以是一个或多个发光二极管。 场透镜可以是双凸透镜。
-
公开(公告)号：AU2013231910A1
公开(公告)日：2014-10-30
申请号：AU2013231910
申请日：2013-03-15
Applicant: LIFE TECHNOLOGIES CORP
Inventor： PALLAS MICHAEL C , NURSE JAMES , LIM GARY , STRAUB THEODORE , GHENCIU ELIODOR , FOSTER EVAN , FONSECA JORGE , MAHER KEVIN
Abstract: A system for performing biological reactions is provided. The system includes a chip including a substrate and a plurality of reaction sites. The plurality of reaction sites are each configured to include a liquid sample of at most one nanoliter. Further, the system includes a control system configured to initiate biological reactions within the liquid samples. The system further includes a detection system configured to detect biological reactions on the chip. According to various embodiments, the chip includes at least 20000 reaction sites. In other embodiments, the chip includes at least 30000 reaction sites.
-
公开(公告)号：WO2013138706A3
公开(公告)日：2014-01-16
申请号：PCT/US2013032002
申请日：2013-03-15
Applicant: LIFE TECHNOLOGIES CORP
Inventor： PALLAS MICHAEL , NURSE JAMES C , MAHER KEVIN , FONSECA JORGE , GHENCIU ELIODOR , FOSTER EVAN
CPC classification number: B01L3/50857 , B01L3/50 , B01L3/50851 , B01L2200/141 , B01L2300/0893 , B01L2300/0896 , B01L2300/161 , C12Q1/6806 , C12Q1/686 , G03F7/2002
Abstract: An article for holding a plurality of biological samples includes a substrate a substrate comprising a first surface and an opposing second surface and a plurality of reaction sites in the substrate. Each of the reaction sites extends from an opening in the first surface to an opening in the second surface. The reaction sites comprise a hexagonal shape and are configured to provide sufficient surface tension by capillary action to hold respective biological samples. The reaction sites have a density over at least a portion of the surfaces that is at least 170 holes per square millimeter. At least one of the surfaces may have a surface roughness characterized by an arithmetic average roughness (Ra) that is less than or equal to 5 nanometers.
Abstract translation: 用于保持多个生物样品的制品包括基材，其包含基材中的第一表面和相对的第二表面和多个反应位点。 每个反应位点从第一表面中的开口延伸到第二表面中的开口。 反应位点包括六边形形状并且被配置为通过毛细作用提供足够的表面张力以保持各自的生物样品。 反应部位的表面密度至少在每平方毫米170个孔以上。 至少一个表面可以具有由小于或等于5纳米的算术平均粗糙度（Ra）表征的表面粗糙度。
-
公开(公告)号：WO2012006084A2
公开(公告)日：2012-01-12
申请号：PCT/US2011042176
申请日：2011-06-28
Applicant: LIFE TECHNOLOGIES CORP , DANEHY RONALD , FONSECA JORGE , PRASAD JAYANTHI
Inventor： DANEHY RONALD , FONSECA JORGE , PRASAD JAYANTHI
CPC classification number: B01L3/56 , B01L3/0275 , B01L3/0293 , B01L2200/025 , B01L2300/161 , G01N35/1011 , G01N35/1074 , G01N2035/103
Abstract: A system for preparing biological sample contains a body including a proximal side and a distal side, a plurality of mandrels, a plurality of resilient elements, a plurality of fluid dispensers, and one or more samples. The mandrels are moveably positioned within the body, where each resilient element engages a respective one of the mandrels. Each of the fluid dispensers is configured to engage a distal end of a corresponding one of the mandrels. Each sample comprises a solution containing one or more nucleic acid sequences contained within at least one of the fluid dispensers.
Abstract translation: 用于制备生物样品的系统包含主体，其包括近侧和远侧，多个心轴，多个弹性元件，多个流体分配器和一个或多个样品。 心轴可移动地定位在体内，其中每个弹性元件接合相应的一个心轴。 每个流体分配器构造成接合相应的一个心轴的远端。 每个样品包含含有至少一种流体分配器中的一种或多种核酸序列的溶液。
-
Patent Agency Ranking
公开(公告)号：IN8135DEN2014A
公开(公告)日：2015-05-01
申请号：IN8135DEN2014
申请日：2014-09-29
Applicant: LIFE TECHNOLOGIES CORP
Inventor： PALLAS MICHAEL C , NURSE JAMES , LIM GARY , STRAUB THEODORE , GHENCIU ELIODOR , FOSTER EVAN , FONSECA JORGE , MAHER KEVIN
Abstract: A system for performing biological reactions is provided. The system includes a chip including a substrate and a plurality of reaction sites. The plurality of reaction sites are each configured to include a liquid sample of at most one nanoliter. Further the system includes a control system configured to initiate biological reactions within the liquid samples. The system further includes a detection system configured to detect biological reactions on the chip. According to various embodiments the chip includes at least 20000 reaction sites. In other embodiments the chip includes at least 30000 reaction sites.
-
公开(公告)号：CA2915475A1
公开(公告)日：2014-11-27
申请号：CA2915475
申请日：2014-05-27
Applicant: LIFE TECHNOLOGIES CORP
Inventor： PALLAS MICHAEL , FOSTER EVAN , FONSECA JORGE , NURSE JAMES , STRAUB THEODORE
IPC: B01L3/00
Abstract: A system for processing a plurality of biological samples contains a support and a temperature controller. The support is configured to hold a case that includes an inner chamber and a substrate located within the inner chamber, the substrate containing a plurality of isolated reaction sites containing one or more biological samples. The temperature controller is configured to maintain or control a temperature of at least one of the support, the case, or the one or more biological samples during an assay or reaction on the one or more biological samples. The support is also configured to maintain at least one of the surfaces of substrate at a positive angle relative to a horizontal plane during the assay or reaction.
-
公开(公告)号：SG11201406039WA
公开(公告)日：2014-11-27
申请号：SG11201406039W
申请日：2013-03-15
Applicant: LIFE TECHNOLOGIES CORP
Inventor： PALLAS MICHAEL , NURSE JAMES C , MAHER KEVIN , FONSECA JORGE , GHENCIU ELIODOR , FOSTER EVAN
Abstract: A system for performing biological reactions is provided. The system includes a chip including a substrate and a plurality of reaction sites. The plurality of reaction sites are each configured to include a liquid sample of at most one nanoliter. Further, the system includes a control system configured to initiate biological reactions within the liquid samples. The system further includes a detection system configured to detect biological reactions on the chip. According to various embodiments, the chip includes at least 20000 reaction sites. In other embodiments, the chip includes at least 30000 reaction sites.
-
公开(公告)号：AU2006292354A1
公开(公告)日：2007-03-29
申请号：AU2006292354
申请日：2006-09-15
Applicant: LIFE TECHNOLOGIES CORP
Inventor： YODER KARL , FONSECA JORGE , MORRISON TOM , ELLIS ROBERT , LINTON JOHN , KATZ ARRIN , HASAN LEILA , BRENAN COLIN
Abstract: A system for thermal cycling a plurality of samples. The system includes a case having a fluid-tight cavity defining an interior volume. A microfluidic array is disposed in the interior volume, the array including a sheet of material having a pair of opposed surfaces, a thickness, and a plurality of through-holes running through the thickness between the surfaces. A thermal cycler having at least one thermally controlled surface is adapted to thermally contact the case.
-
公开(公告)号：SG10201602113TA
公开(公告)日：2016-04-28
申请号：SG10201602113T
申请日：2012-09-28
Applicant: LIFE TECHNOLOGIES CORP
Inventor： FREUDENTHAL JACOB K , DAHLHOFF GEOFFREY , MAHER KEVIN , CHEN MINGSONG , LIM GARY , DANEHY RONALD , FORTESCUE DAVID , SHEN MING , SOH WOON LIANG TERENCE , CHENG FRANCIS , WU RUOYUN , LEE THIAM CHYE , CHAPPELL GARY , LIM CHEE KIONG , DERE JEFF , STRAUB TED , FONSECA JORGE , BOO KUAN MOON , LAU SOO YONG
-
-
-
-
-
-
-
-
-
Search Results
17
records
(took 0.035 seconds)
