公开(公告)号：AU2009264385A1

公开(公告)日：2009-12-30

申请号：AU2009264385

申请日：2009-06-22

Applicant: BASF SE

Inventor： KEIL MICHAEL ,  WISSEL-STOLL KATHRIN ,  MAYWALD VOLKER ,  SCHMIDT-LEITHOFF JOACHIM ,  ALTENHOFF ANSGAR GEREON ,  SMIDT SEBASTIAN PEER

IPC: C07C205/11 ,  C07C205/12

Abstract: Preparation of substituted biphenyl compounds (I), comprises reacting halobenzene compounds (II) with phenyl boronic acid compounds (IVa) and/or diphenyl boronic acid compounds (IVb) in a solvent or a diluent in the presence of a base and a palladium catalyst, which comprises palladium and a bidentate phosphorus ligand (III). Preparation of substituted biphenyl compounds of formula (I), comprises reacting halobenzene compounds of the formula (II) with phenyl boronic acid compounds of formula (IVa) and/or diphenyl boronic acid compounds of formula (IVb) in a solvent or diluent in the presence of a base and a palladium catalyst, which comprises palladium and a bidentate phosphorus ligand of formula (((Ar1) 2P-CH 2-)(R5)C(R4)(-CH 2-P(Ar1) 2)) (III). R1 : NO 2or NH 2; R2 : CN, halo, 1-4C-haloalkyl, 1-4C-haloalkoxy or 1-4C-haloalkylthio; R3 : H, CN or halo; Hal : Cl or Br; Ar1 : phenyl, which optionally contains 1-3 substituents comprising CH 3, CH 3O, F or Cl; either R4, R5 : 1-5C-alkyl or 3-6C-cycloalkyl; or R4R5 : 2-7-membered bridge, which optionally carries 1-8C-alkyl; and n : 0-3. An independent claim is included for 3,4,5-trifluoro-2'-nitrobiphenyl. [Image].

公开(公告)号：AU2009245791A1

公开(公告)日：2009-11-12

申请号：AU2009245791

申请日：2009-05-06

Applicant: BASF SE

Inventor： KORADIN CHRISTOPHER ,  REICHERT WOLFGANG ,  KEIL MICHAEL ,  ZIERKE THOMAS ,  WOLF BERND ,  SMIDT SEBASTIAN PEER ,  MAYWALD VOLKER ,  RACK MICHAEL

IPC: C07D213/82 ,  C07C231/02 ,  C07C233/57 ,  C07C233/64 ,  C07D231/14 ,  C07D231/16

Abstract: A process for preparing arylcarboxamides of the formula (I) where Ar=a mono- to trisubstituted phenyl, pyridyl or pyrazolyl ring, where the substituents are selected from halogen, C1-C4-alkyl and C1-C4-haloalkyl; M=thienyl or phenyl, which may bear a halogen substituent; Q=direct bond, cyclopropylene, fused bicyclo[2.2.1]heptane or bicyclo[2.2.1]heptene ring; R1=hydrogen, halogen, C1-C6-alkyl, C1-C4-alkoxy, C1-C4-haloalkoxy, mono- to trisubstituted phenyl, where the substituents are selected from halogen and trifluoromethylthio, or cyclopropyl; by reacting an acid chloride of the formula (II) with an arylamine (III) in a suitable nonaqueous solvent, wherein, in the absence of an auxiliary base, a) the acid chloride (II) is initially charged, b) a pressure of from 0 to 700 mbar is established, c) the arylamine (III) is metered in an approximately stoichiometric amount and d) the product of value is isolated.

公开(公告)号：AU2009243550A1

公开(公告)日：2009-11-12

申请号：AU2009243550

申请日：2009-05-04

Applicant: BASF SE

Inventor： MAYWALD VOLKER ,  WOLF BERND ,  SUKOPP MARTIN ,  KORADIN CHRISTOPHER ,  ZIERKE THOMAS ,  RACK MICHAEL ,  KEIL MICHAEL

IPC: C07D231/14

Abstract: The present invention relates to a process for preparing 1,3-substituted pyrazole compounds of the formula I in which X is especially a CX1X2X3 group in which X1, X2 and X3 are each independently especially hydrogen, fluorine or chlorine, R1 is C1-C4-alkyl or cyclopropyl, and R2 is hydrogen, CN or a CO2R2a group in which R2a is especially C1-C6-alkyl, comprising the following steps: i) reacting a compound of the formula II with a hydrazone of the formula III where the variables X and R2 in formula II are each as defined for formula I, Y is oxygen, an NRy1 group or an [NRy2Ry3]+Z- group, R3 is OR3a or an NR3bR3c group, and where the variable R1 in formula III is as defined for formula I, R4 and R5 are each independently hydrogen, C1-C6-alkyl, optionally substituted phenyl, where at least one of the R4 and R5 radicals is different from hydrogen, and where R4 and R5 together with the carbon atom to which they are bonded may also be a 5- to 10-membered saturated carbocycle; ii) treating the reaction product obtained with an acid in the presence of water.

公开(公告)号：MX2009003431A

公开(公告)日：2009-04-14

申请号：MX2009003431

申请日：2007-10-12

Applicant: BASF SE

Inventor： MICHEL ALFRED ,  WEVERS JAN HENDRIK ,  ZAGAR CYRILL ,  SIEVERNICH BERND ,  KEIL MICHAEL ,  REINHARD ROBERT ,  HAMPRECHT GERHARD ,  SEITZ WERNER ,  WOLF BERND ,  GEBHARDT JOACHIM ,  MAYER GUIDO ,  ERK PETER ,  SCHMIDT THOMAS ,  COX GERHARD ,  LOEHR SANDRA ,  SAXELL HEIDI EMILIA

IPC: C07D239/54 ,  A01N43/48

Abstract: Hidratos de 2-cloro-5-[3,6-dihidro-3-metil-2,6-dioxo-4-(trifluorom etil)-1-(2H)-pirimidinil]-4-flúor-N-[[metil-(1-metiletil)amino]su lfonil]benzamida. También un proceso para la preparación de estos hidratos y formulaciones destinadas a la fitoprotección que comprenden hidratos del feniluracilo I.

公开(公告)号：SI1893586T1

公开(公告)日：2008-12-31

申请号：SI200630086

申请日：2006-05-18

Applicant: BASF SE

Inventor： GEBHARDT JOACHIM ,  LOHR SANDRA ,  KEIL MICHAEL ,  SCHMIDT THOMAS ,  WEVERS JAN HENDRIK ,  ZECH HELMUT ,  HABERLE RUDOLF

IPC: C07D239/00

公开(公告)号：AT408604T

公开(公告)日：2008-10-15

申请号：AT06755248

申请日：2006-05-18

Applicant: BASF SE

Inventor： GEBHARDT JOACHIM ,  LOEHR SANDRA ,  KEIL MICHAEL ,  SCHMIDT THOMAS ,  WEVERS JAN HENDRIK ,  ZECH HELMUT ,  HAEBERLE RUDOLF

IPC: C07D239/54

Abstract: The present invention relates to a process for preparing 1-alkyl-3-phenyluracils of the formula I where the variables R1 to R7 are as defined in the description by reacting 3-phenyluracils of the formula II and alkylating agents of the formula III R1-L1  III, with one another, wherein during the entire reaction the pH is kept in a range from 1 to 6 by adding base a little at a time.

公开(公告)号：AU2007316720A1

公开(公告)日：2008-05-15

申请号：AU2007316720

申请日：2007-11-05

Applicant: BASF SE

Inventor： KEIL MICHAEL ,  KUHN OLIVER ,  LONGLET JON J ,  SUKOPP MARTIN ,  GRONING CARSTEN

IPC: C07D231/44 ,  A01N43/00 ,  A01N43/56 ,  A61K31/415 ,  A61P33/00

Abstract: The present invention relates to a process for the sulfinylation of a pyrazole derivative, characterized in that 5-amino-1-[2,6-dichloro-4-(trifluoromethyl)phenyl]-1H-pyrazole-3-carbonitrile (II) is reacted with a sulfinylating agent S in the presence of at least one amine acid complex wherein the amine(s) are selected from cyclic secondary amines and the acid(s) are selected from sulfonic acid derivatives, and with the addition of a halogenating agent, wherein S is [CF3S(O)]2O; or CF3S(O)X wherein X means fluoro, chloro, bromo, iodo, a hydroxy group, or an alkaline or alkaline earth metal salt of the hydroxy group; or mixtures thereof.