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公开(公告)号：KR1020140006509A
公开(公告)日：2014-01-16
申请号：KR1020120073600
申请日：2012-07-06
Applicant: (주)케비젠
CPC classification number: C12N1/20 , A23C9/123 , A23L33/10 , A23L33/135 , A61K35/74
Abstract: The present invention provides a Bifidobacterium longum CGB-C11 (deposition number KCTC 11979BP) strain, which is a strain producing conjugated linoleic acid (CLA). The strain of the present invention has excellent CLA production capacity, and strong resistance to acid including gastric acid and bile and an antibiotic. A composition containing the strain is formed into a capsule containing the strain and CLA and coated with a coating material formed of a dairy product, powder, and water soluble polysaccharide, and can be applied to food, drink, animal feed, functional food, and medicines.
Abstract translation: 本发明提供作为产生共轭亚油酸（CLA）的菌株的双歧杆菌CGB-C11（保藏号KCTC 11979BP）菌株。 本发明的菌株具有优异的CLA生产能力，并且对酸，包括胃酸和胆汁以及抗生素具有很强的耐受性。 将含有菌株的组合物形成为含有菌株和CLA的胶囊，并涂布由乳制品，粉末和水溶性多糖形成的涂层材料，并且可以应用于食品，饮料，动物饲料，功能性食品和 药品。
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公开(公告)号：KR1020120043369A
公开(公告)日：2012-05-04
申请号：KR1020100104645
申请日：2010-10-26
Applicant: 재단법인 전주농생명소재연구원 , (주)케비젠
Abstract: PURPOSE: A strain producing conjugated linoleic acid isolated from first milk is provided to ensure excellent conjugated linoleic acid producing ability without resistance to vancomycin antibiotic. CONSTITUTION: An Enterococcus faecalis strain produces conjugated linoleic acid. The deposit number of the strain is Enterococcus faecalis JBMI Ca009(deposit number KACC 91590P). The strain is isolated from human first milk and has one or more characteristic of acid resistance, bile acid resistance, and thermal resistance. A microorganism agent for producing the conjugated linoleic acid contains the Enterococcus faecalis or culture liquid thereof as an active ingredient. A functional food contains the strain or culture liquid thereof as an active ingredient.
Abstract translation: 目的：提供从第一奶中分离的产生共轭亚油酸的菌株，以确保对万古霉素抗生素无抗性的优异的共轭亚油酸生产能力。 构成：粪肠球菌菌株产生共轭亚油酸。 菌株的保藏号为粪肠球菌JBMI Ca009（保藏号KACC 91590P）。 该菌株与人类第一乳分离，具有耐酸性，耐胆汁酸性和耐热性的一个或多个特征。 用于生产共轭亚油酸的微生物剂含有粪肠球菌或其培养液作为活性成分。 功能性食品含有作为活性成分的菌株或培养液。
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公开(公告)号：KR1020090042105A
公开(公告)日：2009-04-29
申请号：KR1020070108023
申请日：2007-10-25
Applicant: (주)케비젠
CPC classification number: A61K48/005 , A61K38/005 , A61K38/16 , C12N15/113 , Y10S514/825 , Y10S514/866 , Y10S514/909
Abstract: A composition containing AROS(active regulator of sirt1) proteins or genes thereof is provided to treat or prevent diabetes, obesity, cancer, neurodegenerative diseases or aging-related diseases by regulating SIRT1 activity. A composition for regulating SIRT1 activity comprises AROS(ACTIVE REGULATOR OF SIRT1) proteins or genes coding the AROS proteins as active ingredients. The composition for regulating SIRT1 activity includes AROS protein antibody, AROS SiRNA, AROS antisense DNA or cell strain containing the DNA thereof. The AROS proteins or the genes coding the AROS proteins are administered to mammal to prevent and treat diabetes, obesity, cancer, neurodegenerative diseases or aging-related diseases.
Abstract translation: 提供含有AROS（sirt1活性调节剂）蛋白质或其基因的组合物，以通过调节SIRT1活性来治疗或预防糖尿病，肥胖症，癌症，神经变性疾病或老化相关疾病。 用于调节SIRT1活性的组合物包括AROS（SIRT1的活性调节因子）或编码AROS蛋白的基因作为活性成分。 用于调节SIRT1活性的组合物包括AROS蛋白抗体，AROS SiRNA，AROS反义DNA或含有其DNA的细胞株。 将AROS蛋白或编码AROS蛋白的基因施用于哺乳动物以预防和治疗糖尿病，肥胖症，癌症，神经变性疾病或老化相关疾病。
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公开(公告)号：KR100782984B1
公开(公告)日：2007-12-07
申请号：KR1020060036360
申请日：2006-04-21
Applicant: (주)케비젠
Abstract: 본 발명은 (a) 유청분말, 저지방탈지분유, 글루코오스 또는 박토트립톤 중에서 선택된 1종, 글리세린 및 배지용액을 멸균 호화시킨 후 유산균을 부가하여 이를 균질화시켜 1차 코팅 물질을 제조하는 단계; (b) 상기에서 제조된 1차 코팅 물질에 정제 가공유와 폴리글리세린지방산 에스테르 및 글리세린호박산지방산 에스테르를 혼합 균질화시켜 2차 코팅 물질을 제조하는 단계; (c) 탄수화물, 단백질 성분 및 검류 증점제, 유화제를 혼합하여 호화 균질화시킨 후, 2차 코팅물질을 부가하여 균질시켜 3차 코팅 물질을 제조하여 멸균된 냉각수 속에 분무하는 단계를 포함하는 유산균 다중 마이크로캡슐 제조방법, 이 방법으로 제조된 마이크로캡슐, 이 마이크로캡슐을 포함하는 제품에 관한 것이다. 상기 방법으로 제조된 마이크로캡슐은 4℃에서 3개월 이상 유산균 생균수가 10
8 CFU/mL 이상으로 유지되는 작용효과를 나타낸다.
CLA 생산 특허균주, 유산균, 다중 마이크로캡슐, 생균수-
25.发明授权유산균-불포화지방산 마이크로캡슐-크릴분말 제조방법, 이방법에 의해 제조된 분말 및 이를 함유하는 장류 失效制备酸乳杆菌不饱和脂肪酸微球蛋白粉的方法，由该方法制备的粉末和包含粉末的SPICER
公开(公告)号：KR100777210B1
公开(公告)日：2007-11-28
申请号：KR1020060048084
申请日：2006-05-29
CPC classification number: A23P10/30 , A23L11/20 , A23L33/00 , A23L33/135 , A23P10/20 , A23P10/40 , A23V2002/00 , A23V2200/222 , A23V2250/194 , A23Y2220/00 , A23Y2300/00
Abstract: A lactobacillus-unsaturated fatty acid microcapsulated-krill powder is provided to be used as a functional additive having merits of lactobacillus-unsaturated fatty and krill, and a method for preparing the soy containing the lactobacillus-unsaturated fatty acid microcapsulated-krill powder are provided to improve the storage stability even at a room temperature. A method for preparing a lactobacillus-unsaturated fatty acid microcapsulated-krill powder comprises the steps of mixing carbohydrate, protein, gum thickener and water to prepare a microcoating material; mixing an emulsifier and a hardened oil, heating them, and adding a lactobacillus and an unsaturated fatty acid to it to homogenize them, thereby preparing an encapsulating material; mixing the microcoating material and the encapsulating material in the presence of an emulsifier; spraying the obtained one into cooling water to prepare microcapsules; and mixing the microcapsules by using a krill powder as a stabilizer to obtain a powder.
Abstract translation: 提供乳酸杆菌不饱和脂肪酸微囊化磷虾粉末作为具有乳酸杆菌不饱和脂肪和磷虾的优点的功能性添加剂，并且提供含有乳酸杆菌不饱和脂肪酸微胶囊化磷酸粉末的大豆的方法 即使在室温下也能提高储存稳定性。 一种制备乳杆菌不饱和脂肪酸微胶囊化磷酸钙粉末的方法包括将碳水化合物，蛋白质，胶增稠剂和水混合以制备微包衣材料的步骤; 混合乳化剂和硬化油，加热，并向其中加入乳杆菌和不饱和脂肪酸使其均化，由此制备包封材料; 在乳化剂存在下混合微包衣材料和包封材料; 将得到的粉末喷入冷却水中以制备微胶囊; 并通过使用磷虾粉末作为稳定剂将微胶囊混合，得到粉末。
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Patent Agency Ranking26.发明公开내열성 아라비노오스 이성화효소 활성을 갖는 신규한지오바실러스 더모디니트리피컨스 CBG-Al 균주, 그 효소 및타가토오스의 생산방법 有权氨基甜菜碱热休克蛋白CBG-AL菌株，表达可热解的L-阿拉伯糖异构酶活性，该酶和标签产生方法
公开(公告)号：KR1020060120197A
公开(公告)日：2006-11-24
申请号：KR1020067011632
申请日：2003-11-15
Applicant: (주)케비젠
Abstract: A Noble Geobacillus thermodenitrificans CBG-Al strain is provided to be able to stably produce D-tagatose at high temperature of 70 more than deg.C. And a method for producing tagatose is provided to be able to economically and significantly increase the tagatose production amount by using environment-friendly and relatively cheap substrate. The Geobacillus thermodenitrificans CBG-Al strain has more than 2.8 unit/mg of thermostable L-arabinose isomerase activity at a temperature of 70 deg.C and is deposited as a deposition number of KCTC 10399BP. The thermostable arabinose isomerase enzyme is produced by the Geobacillus thermodenitrificans CBG-Al strain and has a molecular weight of 56kDa, an isoelectric point of 5.3, an optimum enzymatic reaction pH of 8.0 and maximum thermostability at 60 deg.C. To produce tagatose from galactose, the Geobacillus thermodenitrificans CBG-Al strain is used.
Abstract translation: 提供了一种高贵的地热芽孢杆菌CBG-Al菌株，能够在70℃以上的高温下稳定地生产D-塔格糖。 提供生产塔格糖的方法能够通过使用环境友好且相对廉价的基材来经济地且显着地增加塔格糖的产生量。 热过氧亚硝酸芽孢杆菌CBG-A1菌株在70℃的温度下具有高于2.8单位/ mg的热稳定的L-阿拉伯糖异构酶活性，并以KCTC 10399BP的沉积数存入。 热稳定性阿拉伯糖异构酶由热裂解芽孢杆菌CBG-Al菌株产生，分子量为56kDa，等电点为5.3，最适酶反应pH为8.0，最高热稳定性为60℃。 为了从半乳糖生产塔格糖，使用热过氧硝酸芽孢杆菌CBG-A1菌株。
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公开(公告)号：KR1020060104178A
公开(公告)日：2006-10-09
申请号：KR1020050026100
申请日：2005-03-29
CPC classification number: A61K8/97 , A61K8/19 , A61K36/40 , A61K36/73 , A61K36/815 , A61K2236/33 , A61Q19/02 , Y10S514/844
Abstract: 본 발명은 산수유, 구기자, 복분자, 해송자, 진주가루 추출물을 함유하는 미백용 화장료 조성물을 제공한다.
본 발명의 미백용 화장료 조성물은 티로시나제 활성을 억제하는 효과가 있고, 멜라닌 생성을 억제하는 효과가 있으며, 세포독성이 낮아 피부에 자극이 없어 안전하므로 피부 미백용 화장품에 유용하게 사용될 수 있다.-
公开(公告)号：KR100514593B1
公开(公告)日：2005-09-13
申请号：KR1020050004128
申请日：2005-01-17
Applicant: (주)케비젠
IPC: C12N1/20
CPC classification number: C12P7/6427 , A23C9/1234 , A23C11/106 , A23L33/12 , A23L33/135 , A23P10/30 , A23Y2300/59 , A61K35/744 , A61K35/745 , C12R1/13
Abstract: 본 발명은 공역화 리놀레인산(CLA)을 생산할 수 있는 신규한 균주에 관한 것이다.
본 발명의 균주에는 비피도박테리움 브레베(
Bifidobacterium breve ) CBG-C2 균주, 비피도박테리움 슈도카르테눌라툼(
Bifidobacterium pseudocartenulatum ) CBG-C4 균주 및 엔테로코커스 패시움(
Enterococcus faecium ) CBG-C5 균주가 포함된다.
본 발명의 균주는 CLA 생산 능력이 우수하며, CLA를 생성하여 배지로 분비하는 한편 균체 내에 축적할 수 있다. 또한 본 발명의 균주는 위산이나 담즙 등의 산과 항생물질에 대해 강한 내성을 지닌다.
본 발명의 균주를 포함하는 조성물은 수용성 다당류로 이루어진 피복물질 내에 본 발명의 균주와 CLA를 포함하는 캡슐제 형태로 제조되어, 기능성 식품 및 의약품으로 사용될 수 있다.-
公开(公告)号：KR1020030089396A
公开(公告)日：2003-11-21
申请号：KR1020020066071
申请日：2002-10-29
Applicant: (주)케비젠
IPC: A61K36/488 , A61P35/00
Abstract: PURPOSE: Provided is an anticancer composition comprising the alcohol extract of Pueraria sp. roots, which has excellent anticancer activity with less adverse effect and is thus useful for the prevention and treatment of cancer. CONSTITUTION: An anticancer composition is characterized by containing the alcohol extract of Pueraria sp. roots including Pueraria mirifica and Pueraria lobata. The alcohol extract is selected from PE1, PE2, PE3, PE4, Sub PE-A, Sub PE-B, Sub PE-C, Sub PE-D, Sub PE-E, Sub PE-F, Sub PE-G, Sub PE-H, Sub PE-D1, Sub PE-D2, and Sub PE-D3.
Abstract translation: 目的：提供包含葛根属酒精提取物的抗癌组合物。 根，具有优异的抗癌活性，副反应较少，因此可用于预防和治疗癌症。 构成：抗癌组合物的特征在于含有葛根属的酒精提取物。 根系包括葛根和葛根。 酒精提取物选自PE1，PE2，PE3，PE4，Sub PE-A，Sub PE-B，Sub PE-C，Sub PE-D，Sub PE-E，Sub PE-F，Sub PE-G，Sub PE-H，Sub-PE-D1，Sub-PE-D2，Sub-PE-D3。
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