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公开(公告)号：KR1020130136381A
公开(公告)日：2013-12-12
申请号：KR1020130052956
申请日：2013-05-10
Applicant: 대한민국(관리부서:국립수산과학원)
CPC classification number: C12N15/70
Abstract: The present invention relates to an expression vector for controlling total expression of Active foreign proteins comprising 1) a promoter, 2) a restriction enzyme recognition unit for inserting polynucleotide encoding foreign proteins including translation termination codon, and 3) a gene construct in which trinucleotide repeated body of hexanucleotide are linked in a sequence manner.
Abstract translation: 本发明涉及用于控制活性外源蛋白质的总表达的表达载体，其包括1）启动子，2）用于插入编码包含翻译终止密码子的外源蛋白的多核苷酸的限制酶识别单元，和3）三核苷酸重复的基因构建体 六核苷酸体以序列方式连接。
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公开(公告)号：KR101185841B1
公开(公告)日：2012-10-17
申请号：KR1020090105447
申请日：2009-11-03
Applicant: 대한민국(관리부서:국립수산과학원)
Abstract: 본 발명은 리파아제를 생산하는 신규 포토박테리움 갯버리코라 Gung47(
Photobacterium
gaetbulicola
Gung47) 균주(기탁번호: KACC91494P)에 관한 것으로, 구체적으로 갯벌에서 분리한, 그람 음성이고, 포자를 형성하지 않으며, 혐기성 조건에서도 성장이 가능하고, 지방분해 활성이 있는 신규 포토박테리움 갯버리코라 Gung47에 관한 것이다. 상기 균주가 생산하는 리파아제는 지방을 분해함으로써 세제, 표백제 및 식품, 사료 첨가제 등으로 유용하게 이용될 수 있다.
리파아제(lipase), 포토박테리움(photobacterium), 그람음성-
公开(公告)号：KR101186150B1
公开(公告)日：2012-10-02
申请号：KR1020100113932
申请日：2010-11-16
Applicant: 대한민국(관리부서:국립수산과학원) , 씨제이제일제당 (주)
CPC classification number: A61K35/742 , A23K10/18 , A23K50/80 , C12R1/07
Abstract: 프로바이오틱스 활성을 갖는 신규 바실러스속 균주가 제공된다. 본 발명의 균주는 다양한 어류 병원성 세균에 대한 항균활성을 가지고 있을 뿐만 아니라, 프로테아제, 아밀라제, 셀룰라제, 리파제 등 사료의 소화흡수에 도움을 주는 유용한 효소를 분비하는 등 프로바이오틱스로서 기능을 하기 때문에, 어류 및 갑각류의 사료 첨가제로 유용하게 사용될 수 있다.
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公开(公告)号：KR1020120052667A
公开(公告)日：2012-05-24
申请号：KR1020100113932
申请日：2010-11-16
Applicant: 대한민국(관리부서:국립수산과학원) , 씨제이제일제당 (주)
CPC classification number: A61K35/742 , A23K10/18 , A23K50/80 , C12R1/07
Abstract: PURPOSE: A novel Bacillus strain with a probiotic activity is provided to ensure antibacterial activity to fish pathogenic bacteria and to secrete useful enzymes. CONSTITUTION: A novel Bacillus 2-4(KCCM11107P) strain has a probiotic activity. A probiotic formulation contains the strain as an active ingredient. A feed or feed additive for cultivating fishes and/or crustaceans contains the strain as an active ingredient. A method for preventing mass mortality caused by pathogen of cultured fishes and/or crustaceans comprises a step of feeding the feed to the fishes and/or crustaceans. The pathogen includes Edwardsiella tarda, Streptococcus iniae, Vibrio anguillarum, Vibrio harveyi or Streptococcus parauberis.
Abstract translation: 目的：提供一种具有益生菌活性的新型芽孢杆菌菌株，以确保对病原菌的抗菌活性，并分泌有用的酶。 构成：一种新型的芽孢杆菌2-4（KCCM11107P）菌株具有益生菌活性。 益生菌制剂含有作为活性成分的菌株。 用于培养鱼类和/或甲壳类动物的饲料或饲料添加剂含有该菌株作为活性成分。 用于预防由鱼类和/或甲壳类动物的病原体引起的大量死亡的方法包括将饲料喂入鱼类和/或甲壳类动物的步骤。 病原体包括Edwardsiella tarda，Streptococcus iniae，Vibrio anguillarum，Vibrio harveyi或Streptococcus parauberis。
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25.发明公开
公开(公告)号：KR1020110076347A
公开(公告)日：2011-07-06
申请号：KR1020090133034
申请日：2009-12-29
Applicant: 대한민국(농촌진흥청장)
IPC: A61K36/258 , A61K36/48 , A61K36/82 , A61P13/08
CPC classification number: A61K36/258 , A23V2250/21 , A61K36/48 , A61K36/82 , A61K2236/331 , Y10S514/968
Abstract: PURPOSE: A composition containing ginseng extract is provided to significantly suppress prostatic hyperplasia and to remarkably suppress growth of benign prostate tissues. CONSTITUTION: A pharmaceutical composition for preventing or treating prostatic hyperplasia contains extract of ginseng, Rhynchosia Nulubilis, and green tea as an active ingredient. The ginseng extract is prepared by pulverizing 600g of ginseng, adding 12 L of water, performing hot water extraction at 100°C for 3 hours, concentrating in a vacuum condenser at 45°C, and freeze-drying. The Rhynchosia Nulubilis extract is prepared by pulverizing 600g of Rhynchosia Nulubilis, adding 12L of water, performing at 100°C for three hours, concentrating at 45°C, and freeze-drying.
Abstract translation: 目的：提供含有人参提取物的组合物，以显着抑制前列腺增生，显着抑制良性前列腺组织的生长。 构成：用于预防或治疗前列腺增生的药物组合物含有人参提取物，龙胆龙胆和绿茶作为活性成分。 人参提取物通过将600g人参粉碎，加入12L水，在100℃下进行热水提取3小时，在45℃的真空冷凝器中浓缩，并进行冷冻干燥。 通过将600g的Rhynchosia Nulubilis粉碎，加入12L水，在100℃下进行3小时，浓缩在45℃下进行冷冻干燥，从而制备Rhynchosia Nulubilis提取物。
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Patent Agency Ranking
公开(公告)号：KR1020110071057A
公开(公告)日：2011-06-28
申请号：KR1020110057469
申请日：2011-06-14
Applicant: 대한민국(관리부서:국립수산과학원)
Abstract: PURPOSE: A novel gene encoding Paralichthys olivaceus-derived beta-defensin is provided to ensure high antibacterial activity and to develop natural antibiotics. CONSTITUTION: A Paralichthys olivaceus-derived antibacterial peptide is a polymepeptide, mutant thereof, or active fragment thereof. The polypeptide is selected from: a polypeptide encoded by cDNA having one of nucleic acids of sequence number s 1-5; a polypeptide encoding a polynucleotide which is hybridized with cDNA having the one of nucleic acids of sequence numbers 1-5; a polypeptide encoded by gDNA having one or nucleic acids of sequence numbers 6-10; a polypeptide encoding the polynucleotide hybridized with the gDNA; or a polypeptide having an amino acid among amino acid sequences of sequence numbers 11-15.
Abstract translation: 目的：提供一种编码Paralichthys olivaceus来源的β-防御素的新基因，以确保高抗菌活性和开发天然抗生素。 构成：来自Paralichthys olivaceus的抗菌肽是多肽，其突变体或其活性片段。 所述多肽选自：由具有序列号为1-5的核酸之一的cDNA编码的多肽; 编码与序列号为1-5的核酸的cDNA杂交的多核苷酸的多肽; 由具有序列号6-10的一个或核酸的gDNA编码的多肽; 编码与所述gDNA杂交的多核苷酸的多肽; 或在序列号11-15的氨基酸序列中具有氨基酸的多肽。
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27.发明公开두충 추출물을 유효성분으로 함유하는 류마티스 관절염의 예방 또는 치료용 약학 조성물 및 건강식품 조성물 有权药物和健康食品组合物，用于预防或治疗包含作为有效成分的EUCOMMIA ULMOID提取物的炎热性脑膜炎
公开(公告)号：KR1020110066263A
公开(公告)日：2011-06-17
申请号：KR1020090122833
申请日：2009-12-11
Applicant: 대한민국(농촌진흥청장)
Abstract: PURPOSE: A pharmaceutical composition containing Eucommia ulmoides extract is provided to ensure anti-inflammation and to develop a agent for preventing and treating rheumatoid arthritis. CONSTITUTION: An Eucommia ulmoides extract has anti-inflammatory activation and osteoclast suppression effect. A pharmaceutical composition for preventing or treating rheumatoid arthritis contains the Eucommia ulmoides extract as an active ingredient. The Eucommia ulmoides extract is a hot water extract of Eucommia ulmoides bark. A health food for preventing or treating rheumatoid arthritis contains the Eucommia ulmoides extract as an active ingredient.
Abstract translation: 目的：提供含有杜仲脂提取物的药物组合物，以确保抗炎和开发用于预防和治疗类风湿性关节炎的药剂。 构成：杜仲提取物具有抗炎活化和破骨细胞抑制作用。 用于预防或治疗类风湿性关节炎的药物组合物含有杜仲脂提取物作为活性成分。 杜仲提取物是杜仲杜鹃树皮的热水提取物。 用于预防或治疗类风湿性关节炎的保健食品含有杜仲脂提取物作为活性成分。
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公开(公告)号：KR1020110005144A
公开(公告)日：2011-01-17
申请号：KR1020090062697
申请日：2009-07-09
Applicant: 대한민국(농촌진흥청장)
IPC: A61K36/258 , A61P25/28 , A23L1/30 , A61P25/16
Abstract: PURPOSE: A composition containing ginseng extract with a nerve protective action is provided to treat and prevent brain-associated diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating nerve diseases contains ginseng extract. The ginseng extract is a crude extract obtained using purified water, ethanol or mixture solvent thereof or non-polar soluble extract obtained using ethanol. The pharmaceutical composition is used in the form of injection formulation, tablet, capsule, liquid or pill. A health food composition for improving brain function contains ginseng extract. The health food composition is used in the form of granule, beverage, gum or tea.
Abstract translation: 目的：提供含有神经保护作用的人参提取物的组合物，用于治疗和预防脑相关疾病。 构成：用于预防和治疗神经疾病的药物组合物含有人参提取物。 人参提取物是使用纯化水，乙醇或其混合溶剂或使用乙醇得到的非极性可溶性提取物获得的粗提取物。 药物组合物以注射制剂，片剂，胶囊，液体或丸剂的形式使用。 用于改善脑功能的保健食品组合物含有人参提取物。 保健食品组合物以颗粒，饮料，口香糖或茶的形式使用。
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公开(公告)号：KR102239382B1
公开(公告)日：2021-04-12
申请号：KR1020200088020
申请日：2020-07-16
Applicant: 대한민국(관리부서:국립수산과학원)
IPC: A01N43/38 , A23K20/132 , C12N1/20 , C12P17/10 , C12R1/01
Abstract: 본발명은독성이없고어병세균및 식중독균에높은항균활성뿐만아니라스쿠티카충에대한항충활성을나타내는항균물질인비올라세인생산능이우수한신규마실리아속(Massilia sp.) 균주및 그의용도를제공한다.
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公开(公告)号：KR102019153B1
公开(公告)日：2019-09-10
申请号：KR1020170154447
申请日：2017-11-20
Applicant: 대한민국(관리부서:국립수산과학원)
IPC: C07K7/06 , A01N63/00 , A23K20/147 , A61K38/00
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