公开(公告)号：AU5145396A

公开(公告)日：1996-10-16

申请号：AU5145396

申请日：1996-03-18

Applicant: BASF AG

Inventor： SPENGLER REINHARD ,  ROSENBERG JOERG ,  BREITENBACH JORG

IPC: A61K9/28 ,  A61K9/14

公开(公告)号：AU5105196A

公开(公告)日：1996-10-08

申请号：AU5105196

申请日：1996-03-09

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  RIEGER JENS ,  ROSENBERG JOERG ,  SANNER AXEL

IPC: A61K9/20 ,  A61K9/16 ,  A61K47/30

公开(公告)号：AU4434196A

公开(公告)日：1996-07-19

申请号：AU4434196

申请日：1995-12-22

Applicant: BASF AG

Inventor： ROSENBERG JORG ,  MAIER WERNER ,  FRICKE HELMUT ,  BREITENBACH JORG

IPC: A61J3/10 ,  A61K9/20 ,  B30B11/16

Abstract: PCT No. PCT/EP95/05117 Sec. 371 Date Jun. 18, 1997 Sec. 102(e) Date Jun. 18, 1997 PCT Filed Dec. 22, 1995 PCT Pub. No. WO96/19962 PCT Pub. Date Jul. 4, 1996A process for the production of divisible tablets by melt calendering in which two molding rolls are combined together, at least one of which has depressions with at least one bar which extends up to the surface line of the molding roll and forms a score.

公开(公告)号：CA2408915C

公开(公告)日：2010-07-27

申请号：CA2408915

申请日：2001-05-29

Applicant: BASF AG

Inventor： BERNDL GUNTHER ,  BREITENBACH JORG ,  HEGER ROBERT ,  STADLER MICHAEL ,  WILKE PETER ,  ROSENBERG JORG

IPC: A61F13/53 ,  A61K9/107 ,  A23P1/02 ,  A23P1/08 ,  A61F13/49 ,  A61K9/16 ,  A61K47/00 ,  A61K47/10 ,  A61K47/12 ,  A61K47/14 ,  A61K47/26 ,  A61K47/32 ,  A61K47/34 ,  A61K47/38

Abstract: The invention relates to self-emulsifying formulations based on an active substance constituent and on a formulation base with a lipid constituent and with a binding agent constituent. The invention also relates to the use of this formulation as a dosed form in the area of life science. The invention also relates to a method for producing self-emulsifying formulations by mixing the formulation constituents while forming a plastic mixture and optionally while preparing the formulations as a dosed form, advantageously while using melt extrusion. The formulations spontaneously form emulsions in water or in aqueous fluids.

公开(公告)号：CA2268077C

公开(公告)日：2007-12-18

申请号：CA2268077

申请日：1997-10-07

Applicant: BASF AG

Inventor： KRATZ DETLEF ,  BREITENBACH JORG ,  LANG SIEGFRIED

IPC: C07D223/10 ,  C07D413/06 ,  A61K8/49 ,  A61K9/00 ,  A61K9/08 ,  A61K31/42 ,  A61K31/445 ,  A61K31/535 ,  A61K31/55 ,  A61K47/06 ,  A61K47/16 ,  A61K47/22 ,  A61Q19/00 ,  C07D207/26 ,  C07D207/263 ,  C07D207/267 ,  C07D207/27 ,  C07D211/40 ,  C07D211/76 ,  C07D227/087 ,  C07D263/18 ,  C07D265/28 ,  C07D265/32 ,  C07D401/06 ,  C07D403/06

Abstract: The present invention relates to a 1,3-bis-(N-lactamyl)propane of general formula (I), wherein radicals R1, R2, R3, R4, R5 and R6 independently stand for hydrogen, alkyl, cycloalkyl, aryl or aralkyl and at least one of said radicals does not stand for hydrogen, (NLac) and (NLac') are the same or different and stand for N-lactamyl radicals. The invention also relates to the use of said substances as a solvent in pharmaceutical and cosmetic agents. Disclosed are novel compounds of formula (I), wherein R1 and methyl and R2-R6 stand for hydrogen.

公开(公告)号：CA2227272C

公开(公告)日：2007-12-11

申请号：CA2227272

申请日：1996-08-21

Applicant: BASF AG

Inventor： BREITENBACH JORG ,  ROSENBERG JOERG

IPC: A61K47/24 ,  A61K9/20 ,  A61K47/44

Abstract: Use of lipids as adjuvents in the production of solid medicinal forms by the melt extrusion process.

公开(公告)号：CA2298659C

公开(公告)日：2007-09-11

申请号：CA2298659

申请日：1998-07-21

Applicant: BASF AG

Inventor： NEUMANN JORG ,  LIEPOLD BERND ,  VOLLGRAF CHRISTIANE ,  ROSENBERG JORG ,  ZEIDLER JURGEN ,  BREITENBACH JORG ,  BERNDL GUNTHER

IPC: A61K31/192 ,  A61J3/00 ,  A61K9/20 ,  A61K47/02 ,  A61K47/22 ,  A61K47/32 ,  A61P29/00

Abstract: The invention relates to a fast acting analgesic, containing ibuprofen as th e active analgesic substance in an auxiliary substance matrix, with a porous structure and a density of greater than 1 - 2.5 g/cm3.

公开(公告)号：CA2211033C

公开(公告)日：2005-04-26

申请号：CA2211033

申请日：1996-02-01

Applicant: BASF AG

Inventor： GRABOWSKI SVEN ,  BREITENBACH JORG ,  ROSENBERG JOERG ,  SANNER AXEL

IPC: A61K9/22 ,  A61K9/20

Abstract: Solid preparations obtainable by the melt extrusion of A) at least one activ e agent, B) a mixture of B1) 10 to 90 wt.% of a water-soluble, thermoplastic polymer and B2) 10 to 90 wt.% of a low-substituted hydroxyprop yl cellulose and C) 0 to 50 wt.% in relation to the total quantity of the preparation of common pharmaceutical auxiliaries.

公开(公告)号：ES2178216T3

公开(公告)日：2002-12-16

申请号：ES98924139

申请日：1998-04-17

Applicant: BASF AG

Inventor： ERNST ANDREAS ,  BREITENBACH JORG ,  SANNER AXEL

IPC: A01N25/04 ,  A01N59/12

Abstract: A process for preparing liquid iodophores with poly-N-vinyllactams and dextrins as carrier materials, which comprises heating a mixture of the carrier materials, iodine and iodide ions or, in place of the iodide ions, a reducing agent in aqueous medium in the presence of a monohydric or polyhydric alcohol having 1 to 6 carbon atoms at from 40 to 100° C.

公开(公告)号：PT809488E

公开(公告)日：2002-11-29

申请号：PT96903958

申请日：1996-02-01

Applicant: BASF AG

Inventor： GRABOWSKI SVEN ,  AXEL SANNER DR ,  ROSENBERG JOERG ,  BREITENBACH JORG

IPC: A61K9/22 ,  A61K9/20

Abstract: PCT No. PCT/EP96/00417 Sec. 371 Date Jul. 30, 1997 Sec. 102(e) Date Jul. 30, 1997 PCT Filed Feb. 1, 1996 PCT Pub. No. WO96/25151 PCT Pub. Date Aug. 22, 1996Solid preparations are obtainable by melt extrusion of A) at least one active compound, B) a mixture of B1) from 10 to 90% by weight of a water-soluble, thermoplastic polymer, and B2) from 10 to 90% by weight of a low-substituted hydroxypropylcellulose, and C) from 0 to 50% by weight, based on the total amount of the preparation, of customary pharmaceutical auxiliaries.