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30 records (took 0.022 seconds)

    25.
    发明专利
    未知

    公开(公告)号：DE102005044736A1

    公开(公告)日：2007-03-22

    申请号：DE102005044736

    申请日：2005-09-19

    Applicant: BASF AG

    Inventor： BREUER MICHAEL ,  FRIEDRICH THOMAS ,  KESELER MARIA

    IPC: C12N9/04 ,  C12N15/53 ,  C12N15/63 ,  C12P7/02 ,  C12P7/22 ,  C12P17/00

    Abstract: The present invention relates to proteins having an enzymatic activity of reducing substituted alkanones such as 3-methylamino-1-(2-thienyl)-propan-1-one. The invention furthermore relates to nucleic acids coding for said proteins, nucleic acid constructs, vectors, genetically modified microorganisms and to methods for preparing optically active substituted alkanols, such as, for example, (S)-3-methylamino-1-(2-thienyl)-(S)-propanol.

    28.
    发明专利
    未知

    公开(公告)号：DE102004022686A1

    公开(公告)日：2005-11-24

    申请号：DE102004022686

    申请日：2004-05-05

    Applicant: BASF AG

    Inventor： STUERMER RAINER ,  KESELER MARIA ,  HAUER BERNHARD ,  FRIEDRICH THOMAS ,  BREUER MICHAEL ,  SCHROEDER HARTWIG

    IPC: C07D333/16 ,  C12N9/04 ,  C12P20060101 ,  C12P7/02 ,  C12P13/00 ,  C12P17/00

    Abstract: The invention relates to a method for producing the optically active alkanols of formula (I), wherein n is an integer of from 0 to 5; Cyc represents an optionally substituted, mononuclear or polynuclear, saturated or unsaturated, carbocylic or heterocyclic ring, and R1 represents halogen, SH, OH, NO2, NR2R3 or NR2R3R4+X−, wherein R2, R3 and R4 independently represent H or a lower alkyl or lower alkoxy group and X− represents a counterion. According to the invention, an enzyme (E) selected from the groups of dehydrogenases, aldehyde reductases and carbonyl reductases is incubated in a medium containing the alkanone of formula (II), wherein n, Cyc and R1 are defined as above, in the presence of reduction equivalents. The compound of formula (II) is enzymatically reduced to the compound of formula (I) and the reduction equivalents consumed during reaction are regenerated by reacting a sacrificial alcohol to the corresponding sacrificial ketone using enzyme (E) and at least partially removing the sacrificial ketone from the reaction medium, and then isolating the product (I) so produced.

    METHOD FOR REMOVING HORN SUBSTANCES FROM ANIMAL SKIN
    29.
    发明专利
    METHOD FOR REMOVING HORN SUBSTANCES FROM ANIMAL SKIN 未知

    公开(公告)号：AU2003273997A1

    公开(公告)日：2004-05-13

    申请号：AU2003273997

    申请日：2003-10-14

    Applicant: BASF AG

    Inventor： TAEGER TILMAN LUDECKE ,  PABST GUNTHER ,  LAMALLE PHILIPPE ,  BREUER MICHAEL ,  KROGER BURKHARD ,  SUBKOWSKI THOMAS ,  LEMAIRE HANS-GEORG

    IPC: C14C1/06

    Abstract: Horny substances are removed from animal hides by a process wherein animal hides are treated in a liquor comprising from 0.05 to 5% by weight, based on the salted weight, of one or more compounds of the formula I or the corresponding alkali metal or alkaline earth metal or ammonium or phosphonium salts thereof, the variables being defined as follows: R 1 is selected from hydrogen and C 1 -C 12 -alkyl, unsubstituted or substituted by one or more S-H or O-H groups; X 1 to X 4 are identical or different and are selected from hydrogen, C 1 -C 4 -alkyl, O-H, S-H and N-HR 2 , R 2 is hydrogen or C 1 -C 12 -alkyl or a C 1 -C 4 -alkyl-C-O group, at least one of the radicals X 1 to X 4 being S-H, and, if R 1 contains neither O-H nor S-H, at least one further radical from among X 1 to X 4 is selected from S-H, OH and NH-R 2 , and furthermore with at least one compound which catalyzes the hydrolysis of peptide bonds.

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