Abstract:
PURPOSE: A composition containing biochanin A or pharmaceutically acceptable salt thereof for treating angiogenesis-associated diseases is provided to treat various diseases. CONSTITUTION: A composition for treating angiogenesis-associated diseases contains biochanin A or pharmaceutically acceptable salt thereof as an active ingredient. The angiogenesis-associated diseases are cancer, diabetetic retinopathy, rheumatic arthritis, psoriasis, inflammation, endometriosis, aging or hemandioma. A pharmaceutical composition for suppressing angiogenesis contains biochanin A or pharmaceutically acceptable salt thereof as an active ingredient.
Abstract:
PURPOSE: A composition containign sesamol or pharmaceutically acceptable salt is provided to suppress angiogenesis and to treat cancer, diabetic retinopathy, rheumatic arthritis, and psoriasis. CONSTITUTION: A composition for treating angiogenesis-associated diseases contains sesemol or pharmaceutically acceptable salt thereof as an active ingredient. The angiogenesis-associated diseases are cancer, diabetic retinopaghy, rheumatic arthritis, psoriasis, inflammation, endometriosis, and hemandioma. The sesamol or pharmaceutically acceptable salt thereof is contained in 0.1-10 wt%.
Abstract:
PURPOSE: A composition containing poly gamma glutamic acid for preventing and treating obesity is provided to suppress differentiation of adipocytes and to activate AMPK(5'AMP-activated protein kinase). CONSTITUTION: A composition for preventing and treating obesity contains poly gamma glutamic acid(PGA) as an active ingredient. The molecular weight of PGA is 100kDa to 15,000kDa. The composition is a pharmaceutical composition or food additive. The composition further contains pharmacologically acceptable carrier. The composition is manufactured in the form of powder, granules, tablets, capsules, suspension, emulsion, syrup, external use, suppository, or sterilized injection solution.
Abstract:
PURPOSE: A composition containing derivatives synthesized from decursin for preventing or treating obesity is provided to suppress fatty acid synthesis. CONSTITUTION: A composition for preventing or treating obesity contains decursinol benzoate which is synthedized from decursin. The decursinol benzoate suppresses fatty acid synthesis by AMPK(5' adenosine monophosphate-activated protein kinase) activity. A method for synthesizing decursinol benzoate comprises: a step of performing enfleurage of dried Angelicae gigantis Radix in methanol at room temperature for seven days and filtering; a step of suspending the methanol extract in distilled water and isolating dichloromethane; and a step of freeze-drying and performing silicagel column chromatography to prepare six fraction.
Abstract:
본발명은이퀄을유효성분으로함유하는후각과민증예방또는치료용약학조성물에관한것이다. 또한, 본발명은이퀄을유효성분으로함유하는후각과민증예방또는개선용건강기능식품에관한것이다. 또한, 본발명은이퀄을함유하는악취억제용방향제조성물에관한것이다. 본발명의이퀄을함유하는조성물은후각자극에의한 cAMP의생성을억제내지감소시켜다양한후각자극물질에대해뇌에서냄새인지를못하게하는역할을한다.
Abstract:
본 발명은 십자화과 또는 산형과 식물 추출물을 포함하는 조성물의 hTRPA1 활성 증가와 관련된 다양한 용도, 예를 들어 자극성 향미제, 비만 치료제 및 hTRPA1 길항제 스크리닝에 대한 용도를 제공한다. 본 발명의 십자화과 또는 산형과 식물 추출물은 hTRPA1 활성화와 관련된 다양한 용도를 제공하며, 천연 화합물로서 인체에 부작용이 비교적 적고 산업적 이용 가능성이 크다. 본 발명의 십자화과 또는 산형과 식물 추출물은 hTRPA1의 활성화와 관련된 인체내 항상성 유지에 도움이 되는 신규한 의약 또는 식품 소재일 뿐만 아니라, hTRPA1의 길항제의 스크리닝에 유용하게 이용될 수 있다.