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公开(公告)号:DE69432687T2
公开(公告)日:2003-11-06
申请号:DE69432687
申请日:1994-09-22
Applicant: ABBOTT LAB
Inventor: CLARK FREDERICK L , CLEMENS JOHN M , HANCE ROBERT B , HENDRICK KENDALL B , TAYI APPARAO , KANEWSKE III , LAGOCKI PETER A , MARTIN RICHARD R , MCDOWELL DOUGLAS D , MERRIAM RICHARD A , MOORE LARRY W , OLEKSAK CARL M , PENNINGTON CHARLES D , RAYMOURE WILLIAM J , RUMBAUGH WILLIAM D , SCHMIDT LINDA S , SCHRIER PAUL R , SMITH B JANE , SPRONK ADRIAN M , WALKER EDNA S , VAUGHT , VICKSTROM , WALKER , WATKINS III , WINTER , WOHLFORD , CLIFT , CLOONAN , MITCHELL , STANTON , YOST , HILLS
IPC: G01N33/483 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01N1/00 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04
Abstract: The invention relates to an automated liquid level sensing system for detecting the presence of liquid in a container, said liquid level sensing system comprising: a vertically oriented, electrically conductive probe positioned above said container; means for vertically moving said probe into and out of said container; a signal source electrically connected to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; a receiving antenna positioned below said container for receiving said transmitted electrical signal; means for analyzing said received electrical signal for indications that said probe has contacted liquid in said container; means for transferring said received electrical signal from said receiving antenna to said analyzing means; and means for indicating that liquid has been detected. Further, the invention also provides for a method for automatically detecting the presence of liquid in a container, said method comprising the steps of: vertically positioning an electrically conductive probe above said container; vertically moving said probe into and out of said container; electrically connecting a signal source to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; positioning a receiving antenna below said container for receiving said transmitted electrical signal; analyzing said received electrical signal for indications that said probe has contacted liquid in said container; transferring said received electrical signal from said receiving antenna to said analyzing means; and indicating that liquid has been detected.
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公开(公告)号:DE69432687D1
公开(公告)日:2003-06-18
申请号:DE69432687
申请日:1994-09-22
Applicant: ABBOTT LAB
Inventor: CLARK FREDERICK L , CLEMENS JOHN M , HANCE ROBERT B , HENDRICK KENDALL B , TAYI APPARAO , KANEWSKE III , LAGOCKI PETER A , MARTIN RICHARD R , MCDOWELL DOUGLAS D , MERRIAM RICHARD A , MOORE LARRY W , OLEKSAK CARL M , PENNINGTON CHARLES D , RAYMOURE WILLIAM J , RUMBAUGH WILLIAM D , SCHMIDT LINDA S , SCHRIER PAUL R , SMITH B JANE , SPRONK ADRIAN M , WALKER EDNA S , VAUGHT , VICKSTROM , WALKER , WATKINS III , WINTER , WOHLFORD , CLIFT , CLOONAN , MITCHELL , STANTON , YOST , HILLS
IPC: G01N33/483 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01N1/00 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10 , H01J49/04
Abstract: The invention relates to an automated liquid level sensing system for detecting the presence of liquid in a container, said liquid level sensing system comprising: a vertically oriented, electrically conductive probe positioned above said container; means for vertically moving said probe into and out of said container; a signal source electrically connected to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; a receiving antenna positioned below said container for receiving said transmitted electrical signal; means for analyzing said received electrical signal for indications that said probe has contacted liquid in said container; means for transferring said received electrical signal from said receiving antenna to said analyzing means; and means for indicating that liquid has been detected. Further, the invention also provides for a method for automatically detecting the presence of liquid in a container, said method comprising the steps of: vertically positioning an electrically conductive probe above said container; vertically moving said probe into and out of said container; electrically connecting a signal source to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; positioning a receiving antenna below said container for receiving said transmitted electrical signal; analyzing said received electrical signal for indications that said probe has contacted liquid in said container; transferring said received electrical signal from said receiving antenna to said analyzing means; and indicating that liquid has been detected.
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公开(公告)号:ES2068844T3
公开(公告)日:1995-05-01
申请号:ES89105114
申请日:1989-03-22
Applicant: ABBOTT LAB
Inventor: BROWN WILLIAM E III , SAFFORD SARAH E , CLEMENS JOHN M
IPC: G01N33/52 , G01N33/543 , G01N33/569 , G01N33/576 , G01N33/76 , G01N33/558
Abstract: A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens, antibodies, or other ligands or DNA segments. The material and device comprises a reaction site having procedural controls and an analyte binding area capable of being simultaneously contacted by the sample and reagent used in the performance of the assay. The procedural controls and analyte binding areas operate to provide readable results as to the presence or absence of analyte and simultaneously verify the assay procedure and therefore the assay result.
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公开(公告)号:DE68920176D1
公开(公告)日:1995-02-09
申请号:DE68920176
申请日:1989-03-22
Applicant: ABBOTT LAB
Inventor: BROWN WILLIAM E , SAFFORD SARAH E , CLEMENS JOHN M
IPC: G01N33/52 , G01N33/543 , G01N33/569 , G01N33/576 , G01N33/76 , G01N33/558
Abstract: A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens, antibodies, or other ligands or DNA segments. The material and device comprises a reaction site having procedural controls and an analyte binding area capable of being simultaneously contacted by the sample and reagent used in the performance of the assay. The procedural controls and analyte binding areas operate to provide readable results as to the presence or absence of analyte and simultaneously verify the assay procedure and therefore the assay result.
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公开(公告)号:CA1332807C
公开(公告)日:1994-11-01
申请号:CA594550
申请日:1989-03-23
Applicant: ABBOTT LAB
Inventor: BROWN WILLIAM E III , SAFFORD SARAH E , CLEMENS JOHN M
IPC: G01N33/52 , G01N33/543 , G01N33/569 , G01N33/576 , G01N33/76 , G01N33/558
Abstract: A novel material and device useful in solid-phase binding assays to determine the presence or amount of an analyte in a test sample, particularly antigens, antibodies, or other ligands or DNA segments. The material and device comprises a reaction site having procedural controls and an analyte binding area capable of being simultaneously contacted by the sample and reagent used in the performance of the assay. The procedural controls and analyte binding areas operate to provide readable results as to the presence or absence of analyte and simultaneously verify the assay procedure and therefore the assay result.
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36.
公开(公告)号:CA2142872A1
公开(公告)日:1994-03-03
申请号:CA2142872
申请日:1993-08-03
Applicant: ABBOTT LAB
Inventor: LENNARTZ LIESELOTTE , MICHEL GERD , METHTA SMRITI U , TASKAR SUHAS , CLEMENS JOHN M , MIMMS LARRY T , CHAU KURT H , VALLARI DAVID S
IPC: A61K39/395 , C12N15/09 , C12Q1/70 , G01N33/576
Abstract: 2142872 9404922 PCTABS00030 A means for determining the effectiveness of interferon therapy in individuals who are infected with Hepatitis C Virus (HCV) and are receiving such therapy. Monitoring the level of anti-HCV IgM and/or anti-GOR IgG provide means for establishing whether or not the infected patient is responding to interferon therapy; such monitoring is especially useful for patients diagnosed with chronic acute HCV infections.
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公开(公告)号:ES2351337T3
公开(公告)日:2011-02-03
申请号:ES04010960
申请日:1994-09-22
Applicant: ABBOTT LAB
Inventor: TAYI APPARAO , MITCHELL JAMES E , HANCE ROBERT B , WATKINS WILLIAM E III , CLARK FREDERICK L , MCDOWELL DOUGLAS D , RAYMOURE WILLIAM J , HILLS DAVID B , CLIFT GILBERT , STANTON ALYN K , SPRONK ADRIAN M , KANEWSKE WILLIAM J III , MARTIN RICHARD R , VAUGHT JAMES A , OLEKSAK CARL M , HENDRICK KENDALL B , SCHRIER PAUL R , PENNINGTON CHARLES D , MOORE LARRY W , CLEMENS JOHN M , WALKER EDNA S , SMITH JANE B , CLOONAN KEVIN M , WOHLFORD ROBERT A , WALKER DONNY RAY , YOST DAVID A , MERRIAM RICHARD A , SCHMIDT LINDA S , VICKSTROM RICHARD L , LAGOCKI PETER A , WINTER GARY E , RUMBAUGH WILLIAM D
IPC: G01N33/483 , G01N35/02 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01N1/00 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/04 , G01N35/10 , H01J49/04
Abstract: Un método para realizar simultáneamente al menos dos análisis, comprendiendo dichos análisis una pluralidad de actividades, para una pluralidad de muestras líquidas en un sistema analítico continuo, comprendiendo dicho método las etapas de: combinar una alícuota de una primera muestra líquida con al menos un reactivo en un primer contenedor de reacción para formar una primera mezcla de reacción de análisis para dicha primera muestra líquida; combinar una alícuota de una segunda muestra líquida con al menos un reactivo en un segundo contenedor de reacción para formar una segunda mezcla de reacción de análisis para dicha segunda muestra líquida; incubar dichas primera y dicha segunda mezcla de reacción de análisis al menos un tiempo; realizar las actividades asociadas con cada análisis distintas de dicha combinación y dicha incubación de la primera y la segunda mezclas de reacción de análisis para completar cada análisis, incluyendo dichas otras actividades analizar las mezclas de reacción de análisis incubadas; y programar las etapas de dicha combinación, dicha incubación, y dichas actividades de realización distintas de dicha combinación y dicha incubación asociadas con cada uno de los análisis de acuerdo con un protocolo predeterminado, especificando dicho protocolo: (a) qué actividades se van a realizar para un análisis dado; (b) el orden en el que se van a realizar dichas actividades de (a); (c) al menos un período de incubación entre dichas actividades de (a), comprendiendo dicho al menos un período de incubación un período nominal de tiempo para la realización de una etapa de incubación entre las actividades de (a) y una ventana de tiempo especificada para añadirla o restarla al período de incubación nominal para variar la duración del período nominal entre las actividades de (a) para optimizar el funcionamiento; (d) cómo se van a realizar dichas actividades de (a); y (e) la duración de dichas actividades de (a).
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公开(公告)号:AT348660T
公开(公告)日:2007-01-15
申请号:AT99951904
申请日:1999-10-12
Applicant: ABBOTT LAB
Inventor: BACH MARK C , BAY DANIEL , CARTER MICHAEL K , CLEMENS JOHN M , DAHLKE DANIEL G , GALITZ CHARLES M , GRAY ROBERT C , HALAKA FOLIM , HERCHENBACH STEVE , KUKLA RONALD E , PEPE CURTIS J , PIERCE MARK , SAFAR SCOTT G , TOTH JULIUS , ZUCK GARY
Abstract: A method of performing a determination of an item of interest in a sample using a single structure is disclosed. A sample is provided accessible to the single structure. A first container for processing the sample is placed in a first process path on the single structure. The sample is transferred to the first container in the first process path. A reagent is added to the first container in the first process path. Contents of the first container is mixed in the first process path. The item of interest in the sample is separated from the contents of the first container in the first process path. The separated item of interest in the sample is transferred from the first container in the first process path to a second container in a second process path on the single structure. Contents of the second container is brought to a first temperature different from a temperature of the first process path in the second process path. The item of interest in the second container is detected in the second process path.
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公开(公告)号:DE69434702D1
公开(公告)日:2006-05-24
申请号:DE69434702
申请日:1994-09-22
Applicant: ABBOTT LAB
Inventor: CLARK FREDERICK L , CLEMENS JOHN M , HANCE ROBERT B , HENDRICK KENDALL B , TAYI APPARAO , KANEWSKE WILLIAM J III , LAGOCKI PETER A , MARTIN RICHARD R , MCDOWELL DOUGLAS D , MERRIAM RICHARD A , MOORE LARRY W , OLEKSAK CARL M , PENNINGTON CHARLES D , RAYMOURE WILLIAM J , RUMBAUGH WILLIAM D , SCHMIDT LINDA S , SCHRIER PAUL R , SMITH B JANE , SPRONK ADRIAN M , WALKER EDNA S , VAUGHT JAMES A , VICKSTROM RICHARD L , WALKER DONNY RAY , WATKINS WILLIAM E III , WINTER GARY E , WOHLFORD ROBERT A , CLIFT GILBERT , CLOONAN KEVIN M , MITCHELL JAMES E , STANTON ALYN K , YOST DAVID A , HILLS DAVID B
IPC: G01N33/483 , G01N35/10 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01F23/284 , G01N1/00 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/02 , G01N35/04 , H01J49/04
Abstract: The invention relates to an automated liquid level sensing system for detecting the presence of liquid in a container, said liquid level sensing system comprising: a vertically oriented, electrically conductive probe positioned above said container; means for vertically moving said probe into and out of said container; a signal source electrically connected to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; a receiving antenna positioned below said container for receiving said transmitted electrical signal; means for analyzing said received electrical signal for indications that said probe has contacted liquid in said container; means for transferring said received electrical signal from said receiving antenna to said analyzing means; and means for indicating that liquid has been detected. Further, the invention also provides for a method for automatically detecting the presence of liquid in a container, said method comprising the steps of: vertically positioning an electrically conductive probe above said container; vertically moving said probe into and out of said container; electrically connecting a signal source to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; positioning a receiving antenna below said container for receiving said transmitted electrical signal; analyzing said received electrical signal for indications that said probe has contacted liquid in said container; transferring said received electrical signal from said receiving antenna to said analyzing means; and indicating that liquid has been detected.
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公开(公告)号:DE69434638D1
公开(公告)日:2006-04-27
申请号:DE69434638
申请日:1994-09-22
Applicant: ABBOTT LAB
Inventor: CLARK FREDERICK L , CLEMENS JOHN M , HANCE ROBERT B , HENDRICK KENDALL B , TAYI APPARAO , KANEWSKE WILLIAM J III , LAGOCKI PETER A , MARTIN RICHARD R , MCDOWELL DOUGLAS D , MERRIAM RICHARD A , MOORE LARRY W , OLEKSAK CARL M , PENNINGTON CHARLES D , RAYMOURE WILLIAM J , RUMBAUGH WILLIAM D , SCHMIDT LINDA S , SCHRIER PAUL R , SMITH B JANE , SPRONK ADRIAN M , WALKER EDNA S , VAUGHT JAMES A , VICKSTROM RICHARD L ALGONQUIN , WALKER DONNY RAY , WATKINS WILLIAM E III , WINTER GARY E , WOHLFORD ROBERT A , CLIFT GILBERT , CLOONAN KEVIN M , MITCHELL JAMES E , STANTON ALYN K , YOST DAVID A , HILLS DAVID B
IPC: G01N33/483 , G01N35/02 , B01F11/00 , B01L3/00 , B29C45/00 , G01F23/22 , G01F23/26 , G01N1/00 , G01N21/25 , G01N21/64 , G01N21/76 , G01N21/78 , G01N33/53 , G01N33/542 , G01N33/543 , G01N33/553 , G01N35/00 , G01N35/04 , G01N35/10 , H01J49/04
Abstract: The invention relates to an automated liquid level sensing system for detecting the presence of liquid in a container, said liquid level sensing system comprising: a vertically oriented, electrically conductive probe positioned above said container; means for vertically moving said probe into and out of said container; a signal source electrically connected to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; a receiving antenna positioned below said container for receiving said transmitted electrical signal; means for analyzing said received electrical signal for indications that said probe has contacted liquid in said container; means for transferring said received electrical signal from said receiving antenna to said analyzing means; and means for indicating that liquid has been detected. Further, the invention also provides for a method for automatically detecting the presence of liquid in a container, said method comprising the steps of: vertically positioning an electrically conductive probe above said container; vertically moving said probe into and out of said container; electrically connecting a signal source to said probe, said signal source energizing said probe with an electrical signal and causing said probe to transmit said electrical signal; positioning a receiving antenna below said container for receiving said transmitted electrical signal; analyzing said received electrical signal for indications that said probe has contacted liquid in said container; transferring said received electrical signal from said receiving antenna to said analyzing means; and indicating that liquid has been detected.
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