公开(公告)号：DE3725273A1

公开(公告)日：1989-02-09

申请号：DE3725273

申请日：1987-07-30

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DR ,  SCHLECKER RAINER DR ,  GRIES JOSEF DR MED ,  PHILIPSBORN GERDA VON DR MED ,  UNGER LILIANE DR

IPC: A61K31/135 ,  A61P9/06 ,  A61P25/02

Abstract: The agents are prepared as described and used for certain groups of patients.

公开(公告)号：DE3425632A1

公开(公告)日：1986-01-16

申请号：DE3425632

申请日：1984-07-12

Applicant: BASF AG

Inventor： GEISS KARL-HEINZ DR ,  RASCHACK MANFRED DR ,  LEHMANN HANS DIETER PROF DR ,  GRIES JOSEF DR MED ,  RUEBSAMEN HANS DR ,  SCHMIED BERNHARD DR

IPC: A61K31/50 ,  A61K31/55 ,  A61P1/04 ,  A61P7/02 ,  A61P9/04 ,  A61P9/12 ,  C07D237/00 ,  C07D403/04 ,  C07D403/10 ,  C07D237/14 ,  A61K31/495

Abstract: Novel pyrrol-1-ylphenyldihydropyridazinones of the formula I their preparation and their use in the treatment of disorders.

公开(公告)号：DE3309595A1

公开(公告)日：1984-09-20

申请号：DE3309595

申请日：1983-03-17

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DR ,  GRIES JOSEF DR MED ,  MUELLER CLAUS D DR MED ,  LENKE DIETER PROF DR

IPC: C07D211/52 ,  A61K31/13 ,  A61K31/445 ,  A61K31/451 ,  A61P9/06 ,  C07C67/00 ,  C07C213/00 ,  C07C217/32 ,  C07C313/00 ,  C07C323/25 ,  C07D211/44 ,  C07D295/08 ,  C07D295/092 ,  C07D303/22 ,  C07C93/14 ,  A61K31/485

Abstract: Compounds of the general formula I where R1, R2, R3, R4 and n have the meanings given in the description, are useful for treating cardiac disorders.

公开(公告)号：DE3144138A1

公开(公告)日：1983-05-19

申请号：DE3144138

申请日：1981-11-06

Applicant: BASF AG

Inventor： KROPP RUDOLF ,  THYES MARCO DR ,  SCHLECKER RAINER DR ,  FRANKE ALBRECHT DR ,  REICHENEDER FRANZ DR ,  AMANN AUGUST DR MED ,  TESCHENDORF HANS-JUERGEN DR ME ,  KRETZSCHMAR ROLF PROF DR MED ,  TRAUT MARTIN DR ,  GRIES JOSEF DR MED

IPC: A61K31/50 ,  A61P9/02 ,  A61P25/00 ,  A61P25/24 ,  A61P25/26 ,  C07D237/20 ,  C07D237/22

公开(公告)号：DE3124699A1

公开(公告)日：1983-01-13

申请号：DE3124699

申请日：1981-06-24

Applicant: BASF AG

Inventor： ROSSY PHILLIP A DIPL CHEM DR ,  THYES MARCO DIPL CHEM DR ,  FRANKE ALBRECHT DIPL CHEM DR ,  KOENIG HORST PROF DIPL CHEM DR ,  GRIES JOSEF DR MED ,  LEHMANN HANS DIETER DR MED ,  LENKE DIETER PROF DR

IPC: A61K31/50 ,  A61K31/55 ,  A61P7/02 ,  A61P9/12 ,  C07D209/34 ,  C07D215/22 ,  C07D215/227 ,  C07D223/16 ,  C07D401/04 ,  C07D403/04 ,  C07D403/10 ,  A61K31/40 ,  A61K31/47 ,  C07D401/10

Abstract: 2-Aryl-3,4-diazabicyclo[4.n.O]alk-2-en-5-ones of the formula I I where m and n are identical or different and each is 1, 2 or 3, and R, R1 and R2 are identical or different and each is hydrogen or alkyl of 1 to 6 C atoms, said compounds are useful for treating high blood pressure and thrombo-embolic disorders.

公开(公告)号：DE3101456A1

公开(公告)日：1982-09-02

申请号：DE3101456

申请日：1981-01-19

Applicant: BASF AG

Inventor： FRANKE ALBRECHT DIPL CHEM DR ,  STEINER GERD DIPL CHEM DR ,  THIEME PETER C DIPL CHEM DR ,  LENKE DIETER PROF DR ,  GRIES JOSEF DR MED ,  TESCHENDORF HANS-JUERGEN DR ME

IPC: C07D249/08 ,  A61K31/41 ,  A61K31/415 ,  A61K31/42 ,  A61K31/495 ,  A61K31/496 ,  A61K31/505 ,  A61P9/02 ,  A61P11/08 ,  A61P25/08 ,  A61P25/20 ,  C07D231/12 ,  C07D231/38 ,  C07D233/60 ,  C07D233/88 ,  C07D239/42 ,  C07D261/08 ,  C07D295/06 ,  C07D295/092 ,  C07D521/00 ,  C07D403/12 ,  C07D403/10 ,  C07D413/12 ,  C07D413/10

Abstract: Novel (hetarylphenoxy)-(phenylpiperazinyl)-propanols of the formula I where R1 is hydrogen, amino or alkyl of 1 to 4 carbon atoms, R2 is hydrogen, halogen, alkyl of 1 to 4 carbon atoms or alkoxy where alkyl is of 1 to 3 carbon atoms, the phenyl ring can be monosubstituted or disubstituted by R2, and the heterocyclic structure Het. is pyrimidinyl, triazol-1-yl, imidazol-1-yl, pyrazol-3-yl or isoxazol-3-yl, and their physiologically tolerated addition salts with acids, processes for their preparation, and pharmaceutical formulations which contain these compounds and exhibit predominantly hypotensive, sedative, neuroleptic and broncholytic properties.

公开(公告)号：DE3006809A1

公开(公告)日：1981-09-24

申请号：DE3006809

申请日：1980-02-23

Applicant: BASF AG

Inventor： SCHLECKER RAINER DIPL CHEM DR ,  FRICKEL FRITZ-FRIEDER DIPL CHE ,  FRANKE ALBRECHT DIPL CHEM DR ,  LENKE DIETER PROF DR ,  GRIES JOSEF DR MED

IPC: A61K31/42 ,  A61P9/00 ,  A61P9/12 ,  A61P25/02 ,  C07D261/08 ,  C07D261/10 ,  C07D261/18 ,  C07F9/653 ,  C07D261/06

公开(公告)号：DE2943406A1

公开(公告)日：1981-05-07

申请号：DE2943406

申请日：1979-10-26

Applicant: BASF AG

Inventor： FRICKEL FRITZ-FRIEDER DIPL CHE ,  THIEME PETER C DIPL CHEM DR ,  FRANKE ALBRECHT DIPL CHEM DR ,  HAGEN HELMUT DIPL ING ,  LENKE DIETER PROF DR ,  GRIES JOSEF DR MED

IPC: A61K31/41 ,  A61K31/433 ,  A61P9/00 ,  A61P9/12 ,  A61P25/02 ,  C07D285/12 ,  A61K31/425

Abstract: Novel aminopropanol derivatives of 2-methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole and their addition salts with acids, their preparation, pharmaceutical formulations containing these compounds, and their use as drugs in the treatment of coronary heart disease, hypertonia and cardiac arrhythmias.

公开(公告)号：DE2818765A1

公开(公告)日：1979-11-08

申请号：DE2818765

申请日：1978-04-28

Applicant: BASF AG

Inventor： THIEME PETER C DIPL CHEM DR ,  FRICKEL FRITZ-FRIEDER DIPL CHE ,  HAGEN HELMUT DIPL ING DR ,  FRANKE ALBRECHT DIPL CHEM DR ,  LENKE DIETER PROF DR ,  GRIES JOSEF DR MED

IPC: A61K31/41 ,  A61K31/433 ,  A61P9/00 ,  A61P9/06 ,  A61P9/12 ,  C07D285/12 ,  C07D417/12 ,  A61K31/425

Abstract: Alkylaminopropanol derivatives of 2-methyl-5-(2-hydroxystyryl)-1,3,4-thiadiazole and their addition salts with acids, their preparation, and pharmaceutical formulations, containing these compounds, which may be used for the treatment of coronary diseases of the heart, of hypertonia and of cardiac arrhythmias.